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WO1998057983A3 - Mammalian neuro-growth factor like protein - Google Patents

Mammalian neuro-growth factor like protein Download PDF

Info

Publication number
WO1998057983A3
WO1998057983A3 PCT/US1998/012763 US9812763W WO9857983A3 WO 1998057983 A3 WO1998057983 A3 WO 1998057983A3 US 9812763 W US9812763 W US 9812763W WO 9857983 A3 WO9857983 A3 WO 9857983A3
Authority
WO
WIPO (PCT)
Prior art keywords
growth factor
protein
neuro
mammalian
mammalian neuro
Prior art date
Application number
PCT/US1998/012763
Other languages
French (fr)
Other versions
WO1998057983A2 (en
Inventor
Paul O Sheppard
Laura J Jelinek
Theodore E Whitmore
Hal Blumberg
Joyce M Lehner
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to JP50483699A priority Critical patent/JP2002506349A/en
Priority to IL13358298A priority patent/IL133582A0/en
Priority to AU79798/98A priority patent/AU737132B2/en
Priority to CA002295439A priority patent/CA2295439A1/en
Priority to NZ501873A priority patent/NZ501873A/en
Priority to EP98930397A priority patent/EP0996628A2/en
Publication of WO1998057983A2 publication Critical patent/WO1998057983A2/en
Publication of WO1998057983A3 publication Critical patent/WO1998057983A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Novel mammalian neuro-growth factor like polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods including antibodies and anti-idiotypic antibodies.
PCT/US1998/012763 1997-06-18 1998-06-18 Mammalian neuro-growth factor like protein WO1998057983A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP50483699A JP2002506349A (en) 1997-06-18 1998-06-18 Mammalian nerve growth factor-like protein
IL13358298A IL133582A0 (en) 1997-06-18 1998-06-18 Mammalian neuro-growth factor like protein
AU79798/98A AU737132B2 (en) 1997-06-18 1998-06-18 Mammalian neuro-growth factor like protein
CA002295439A CA2295439A1 (en) 1997-06-18 1998-06-18 Mammalian neuro-growth factor like protein
NZ501873A NZ501873A (en) 1997-06-18 1998-06-18 Mammalian neuro-growth factor like protein
EP98930397A EP0996628A2 (en) 1997-06-18 1998-06-18 Mammalian neuro-growth factor like protein

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US5014397P 1997-06-18 1997-06-18
US87832297A 1997-06-18 1997-06-18
US60/050,143 1997-06-18
US08/878,322 1997-06-18

Publications (2)

Publication Number Publication Date
WO1998057983A2 WO1998057983A2 (en) 1998-12-23
WO1998057983A3 true WO1998057983A3 (en) 1999-03-18

Family

ID=26727933

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/012763 WO1998057983A2 (en) 1997-06-18 1998-06-18 Mammalian neuro-growth factor like protein

Country Status (7)

Country Link
EP (1) EP0996628A2 (en)
JP (1) JP2002506349A (en)
AU (1) AU737132B2 (en)
CA (1) CA2295439A1 (en)
IL (1) IL133582A0 (en)
NZ (1) NZ501873A (en)
WO (1) WO1998057983A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000053756A2 (en) * 1999-03-08 2000-09-14 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
NZ525914A (en) * 1998-03-10 2004-03-26 Genentech Inc Novel polypeptides and nucleic acids encoding the same
US7723488B2 (en) 1998-03-27 2010-05-25 Genentech, Inc. Monoclonal antibodies to secreted and transmembrane polypeptides
ATE415422T1 (en) * 1998-04-22 2008-12-15 Genentech Inc HUMAN GAS-6 (GROWTH ARREST-SPECIFIC GENE 6) PROTEIN AND NUCLEIC ACIDS CODING THEREOF
WO1999054437A2 (en) * 1998-04-23 1999-10-28 Millennium Pharmaceuticals, Inc. Novel molecules of the t125-related protein family and uses thereof
AU2224800A (en) * 1999-03-08 2000-09-28 Genentech Inc. Compositions and methods for the treatment of tumor
US7217554B2 (en) 1999-08-31 2007-05-15 Novozymes A/S Proteases and variants thereof
AU6820000A (en) 1999-08-31 2001-03-26 Novozymes A/S Novel proteases and variants thereof
AU7377300A (en) * 1999-09-13 2001-04-17 Curagen Corporation Novel human proteins, polynucleotides encoding them and methods of using the same
EP2275549A1 (en) * 2000-06-23 2011-01-19 Genentech, Inc. Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
FR2851249A1 (en) * 2003-02-17 2004-08-20 Commissariat Energie Atomique Using VE-statins to inhibit recruitment of perivascular smooth muscle cells, for treating e.g. cancer and retinopathy, also new VE-statins, related nucleic acids and antibodies
ZA200608615B (en) * 2004-04-14 2008-05-28 Genentech Inc Compositions and methods comprising an EGFL7 antagonist for modulating vascular development
DE102007019162A1 (en) * 2007-04-20 2008-10-23 Johann Wolfgang Goethe-Universität Frankfurt am Main Use of EGFL7 to modulate cells
EP2427493A1 (en) 2009-05-08 2012-03-14 F. Hoffmann-La Roche AG Humanized anti-egfl7 antibodies and methods using same
KR20140142733A (en) * 2012-03-27 2014-12-12 런던 헬스 사이언시스 센터 리서치 인코포레이티드 Egfl7 targeting and/or binding polypeptides and methods for inhibiting angiogenesis

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993012141A1 (en) * 1991-12-11 1993-06-24 Yale University Nucleotide and protein sequences of the serrate gene and methods based thereon
WO1997001571A1 (en) * 1995-06-28 1997-01-16 Imperial Cancer Research Technology, Ltd. Nucleotide and protein sequences of vertebrate delta genes and methods based thereon
WO1997019172A1 (en) * 1995-11-17 1997-05-29 Asahi Kasei Kogyo Kabushiki Kaisha Differentiation-suppressive polypeptide

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993012141A1 (en) * 1991-12-11 1993-06-24 Yale University Nucleotide and protein sequences of the serrate gene and methods based thereon
WO1997001571A1 (en) * 1995-06-28 1997-01-16 Imperial Cancer Research Technology, Ltd. Nucleotide and protein sequences of vertebrate delta genes and methods based thereon
WO1997019172A1 (en) * 1995-11-17 1997-05-29 Asahi Kasei Kogyo Kabushiki Kaisha Differentiation-suppressive polypeptide

Non-Patent Citations (13)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL NUCLEOTIDE AND PROTEIN SEQUENCES, - 17 February 1997 (1997-02-17), HINXTON, GB, XP002085645 *
DATABASE EMBL NUCLEOTIDE AND PROTEIN SEQUENCES, - 29 April 1996 (1996-04-29), HINXTON, GB, XP002085644 *
DATABASE EMBL NUCLEOTIDE AND PROTEIN SEQUENCES, 6 November 1996 (1996-11-06), HINXTON, GB, XP002085643 *
DATABASE WPI Week 9727, Derwent World Patents Index; AN 97-298110 [27], XP002085646 *
JOUTEL A ET AL: "NOTCH3 MUTATIONS IN CADASIL, A HEREDITATY ADULT-ONSET CONDITION CAUSING STROKE AND DEMENTIA", NATURE, vol. 383, no. 6602, 24 October 1996 (1996-10-24), pages 707 - 710, XP002029077 *
KATSANIS N ET AL: "Paralogy mapping: identification of a region in the human MHC triplicated onto human chromosomes 1 and 9 allows the prediction and isolation of novel PBX and NOTCH loci", TRENDS IN GENETICS, vol. 12, no. 9, September 1996 (1996-09-01), pages 344, XP004037158 *
LARDELLI M ET AL: "THE NOVEL NOTCH HOMOLOGUE MOUSE NOTCH 3 LACKS SPECIFIC EPIDERMAL GROWTH FACTOR-REPEATS AND IS EXPRESSED IN PROLIFERATING NEUROEPITHELIUM", MECHANISMS OF DEVELOPMENT, vol. 46, no. 2, May 1994 (1994-05-01), pages 123 - 136, XP000670102 *
LINDSELL C E ET AL: "EXPRESSION PATTERNS OF JAGGED, DELTA1, NOTCH1, NOTCH2, AND NOTCH3 GENES IDENTIFY LIGAND-RECEPTOR PAIRS THAT MAY FUNCTION IN NEURAL DEVELOPMENT", MOLECULAR AND CELLULAR NEUROSCIENCES, vol. 8, no. 1, 1996, pages 14 - 27, XP000670030 *
ROBEY E ET AL: "A MATTER OF CHOICE: NOTCH AND CD8 T-CELL DEVELOPMENT", IMMUNOLOGY TODAY, vol. 18, no. 2, February 1997 (1997-02-01), pages 55, XP004034263 *
ROBEY E ET AL: "AN ACTIVATED FORM OF NOTCH INFLUENCES THE CHOICE BETWEEN CD4 AND CD8 T CELL LINEAGES", CELL, vol. 87, 1 November 1996 (1996-11-01), pages 483 - 492, XP002056588 *
ROBEY E: "NOTCH IN VERTEBRATES", CURRENT OPINION IN GENETICS & DEVELOPMENT, vol. 7, no. 4, August 1997 (1997-08-01), pages 551 - 557, XP002056593 *
SUGAYA K ET AL: "THREE GENES IN THE HUMAN MHC CLASS III REGION NEAR THE JUNCTION WITH THE CLASS II: GENE FOR RECEPTOR OF ADVANCED GLYCOSYLATION END PRODUCTS, PBX HOMEBOX GENE AND A NOTCH HOMOLOG, HUMAN COUNTERPART OF MOUSE MAMMARY TUMOR GENE INT-3", GENOMICS, vol. 23, 1994, pages 408 - 419, XP002037612 *
WEINMASTER G ET AL: "NOTCH2: A SECOND MAMMALIAN NOTCH GENE", DEVELOPMENT, vol. 116, no. 4, 1992, pages 931 - 941 (938, 938A-938D), XP000618731 *

Also Published As

Publication number Publication date
CA2295439A1 (en) 1998-12-23
WO1998057983A2 (en) 1998-12-23
JP2002506349A (en) 2002-02-26
AU7979898A (en) 1999-01-04
AU737132B2 (en) 2001-08-09
NZ501873A (en) 2002-02-01
EP0996628A2 (en) 2000-05-03
IL133582A0 (en) 2001-04-30

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