+

WO1998053800A8 - Compositions et procedes destines a empecher les adherences - Google Patents

Compositions et procedes destines a empecher les adherences

Info

Publication number
WO1998053800A8
WO1998053800A8 PCT/US1998/009903 US9809903W WO9853800A8 WO 1998053800 A8 WO1998053800 A8 WO 1998053800A8 US 9809903 W US9809903 W US 9809903W WO 9853800 A8 WO9853800 A8 WO 9853800A8
Authority
WO
WIPO (PCT)
Prior art keywords
composition
adhesion formation
methods
compositions
fibrosis
Prior art date
Application number
PCT/US1998/009903
Other languages
English (en)
Other versions
WO1998053800A1 (fr
Inventor
Michael V Koroly
Original Assignee
Applied Biotechnology Inc
Michael V Koroly
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Biotechnology Inc, Michael V Koroly filed Critical Applied Biotechnology Inc
Priority to AU76857/98A priority Critical patent/AU7685798A/en
Publication of WO1998053800A1 publication Critical patent/WO1998053800A1/fr
Publication of WO1998053800A8 publication Critical patent/WO1998053800A8/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Composition et méthode permettant de prévenir, réduire ou éliminer la fibrose ou la formation ou reformation d'adhérences chez des mammifères à la suite de lésions chirurgicales, traumatiques, organiques ou de radiothérapie subies par des organes internes, la membrane péritonéale et d'autres espaces corporels. Ladite composition contient des phospholipides qui peuvent être sélectionnés dans le groupe constitué par phosphatidylglycérol, phosphatidylinositol ou phosphatidylsérine, phosphatidylcholine et phosphatidyléthanolamine. La présente invention concerne également une composition et des méthodes permettant d'inhiber la fibrose, la cicatrisation et la formation d'adhérences, du fait que ladite composition permet la restauration de la lubrification naturelle, présente des propriétés de l'activateur tissulaire du plasminogène naturel et une résistance à la alpha phospholipase A2. On inhibe la formation d'adhérences en appliquant ladite composition sur les cavités du corps ayant subi des traumatismes ou susceptibles de les subir.
PCT/US1998/009903 1997-05-29 1998-05-22 Compositions et procedes destines a empecher les adherences WO1998053800A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU76857/98A AU7685798A (en) 1997-05-29 1998-05-22 Compositions and methods for preventing adhesion

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US4801397P 1997-05-29 1997-05-29
US60/048,013 1997-05-29
US5608697P 1997-08-27 1997-08-27
US60/056,086 1997-08-27
US6449597P 1997-11-05 1997-11-05
US60/064,495 1997-11-05

Publications (2)

Publication Number Publication Date
WO1998053800A1 WO1998053800A1 (fr) 1998-12-03
WO1998053800A8 true WO1998053800A8 (fr) 1999-03-25

Family

ID=27367253

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/009903 WO1998053800A1 (fr) 1997-05-29 1998-05-22 Compositions et procedes destines a empecher les adherences

Country Status (2)

Country Link
AU (1) AU7685798A (fr)
WO (1) WO1998053800A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9807298D0 (en) * 1998-04-03 1998-06-03 Britannia Pharmaceuticals Ltd Medicament
GB0115505D0 (en) * 2001-06-25 2001-08-15 Britannia Pharmaceuticals Ltd Prevention of surgical adhesions
GB0207653D0 (en) * 2002-04-03 2002-05-15 Lamellar Therapeutics Ltd Methods of using lamellar bodies for therapeutic purposes
EP1549293A1 (fr) * 2002-09-16 2005-07-06 Vasogen Ireland Limited Acceleration du retablissement suite a des traumas
WO2004082688A1 (fr) * 2003-03-20 2004-09-30 Vasogen Ireland Limited Agonistes et antagonistes de recepteur de phosphatidylglycerol (pg)
GB0322448D0 (en) 2003-09-25 2003-10-29 Lamellar Therapeutics Ltd Using lamellar bodies to modify linear biological macro molecules
US7332179B2 (en) 2003-12-12 2008-02-19 Kimberly-Clark Worldwide, Inc. Tissue products comprising a cleansing composition
GB0426010D0 (en) * 2004-11-26 2004-12-29 Britannia Pharmaceuticals Ltd Improvements in or relating to organic materials
US7642395B2 (en) 2004-12-28 2010-01-05 Kimberly-Clark Worldwide, Inc. Composition and wipe for reducing viscosity of viscoelastic bodily fluids
US9119901B2 (en) 2005-04-28 2015-09-01 Warsaw Orthopedic, Inc. Surface treatments for promoting selective tissue attachment to medical impants
GB0803969D0 (en) * 2008-03-04 2008-04-09 Britannia Pharmaceuticals Ltd Improved phospholipid and method for its production
JP6073552B2 (ja) * 2008-11-14 2017-02-01 アーチャー−ダニエルズ−ミッドランド カンパニー オルガノゲル組成物及び製造方法
EP2568963A4 (fr) 2010-05-14 2014-03-12 Archer Daniels Midland Co Compositions alimentaires comprenant des organogels
GB201511058D0 (en) * 2015-06-23 2015-08-05 Lamellar Biomedical Ltd Compositions and methods for using lamellar bodies for therapeutic purposes
CN114788899B (zh) * 2022-05-07 2023-04-07 西安德诺海思医疗科技有限公司 光固化防粘连凝胶及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5403592A (en) * 1987-08-25 1995-04-04 Macnaught Pty Limited Lubricant composition for rheumatism
GB9112267D0 (en) * 1991-06-07 1991-07-24 Biocompatibles Ltd Polymeric coating
JPH0646831A (ja) * 1992-07-30 1994-02-22 Sumitomo Bakelite Co Ltd 細胞培養基材及びその製造方法
US5462752A (en) * 1994-07-28 1995-10-31 Prp, Inc. Inhibition of platelet binding
US5534261A (en) * 1995-01-17 1996-07-09 University Of Southern California Retinoid-based compositions and method for preventing adhesion formation using the same

Also Published As

Publication number Publication date
WO1998053800A1 (fr) 1998-12-03
AU7685798A (en) 1998-12-30

Similar Documents

Publication Publication Date Title
WO1998053800A8 (fr) Compositions et procedes destines a empecher les adherences
Hills Surface‐active phospholipid: a Pandora’s box of clinical applications. Part II. Barrier and lubricating properties
US5403592A (en) Lubricant composition for rheumatism
Munder et al. Lysophosphatidylcholine (lysolecithin) and its synthetic analogues. Immunemodulating and other biologic effects
IL131348A0 (en) Treatment and prevention of adhesions
MX9703609A (es) Uso de fragmentos de angiotensina ii y analogos de la misma para la preparacion de composiciones en la preparacion de tejido.
AU6062396A (en) Lipids for epidermal moisturization and repair of barrier function
WO2003015612A3 (fr) Materiaux et techniques favorisant la reparation de tissus nerveux
CA2327693A1 (fr) Utilisation de phospholipides pour la fabrication d'un medicament servant a prevenir les adhesions
BR9907189A (pt) Produtos da fração lipìdica do carotenóide de pepino do mar e métodos de uso
PT1121102E (pt) Inibidores da topoisomerase aprisionados em lipossoma
BR0014205A (pt) Composição de tratamento para aplicação em e penetração para dentro de tecido lesionado
CA2467064A1 (fr) Compositions a vecteurs lipidiques a stabilite sanguine accrue
AUPR177300A0 (en) Therapeutic methods
WO2001045641A3 (fr) Inhibiteurs d'agregation de plaquettes induite par thrombine
AU2002319961A1 (en) Enteral compositions for the prevention and/or treatment of sepsis
AU2731200A (en) Composition and method for treating nails and adjacent tissues
AU1023497A (en) Tissue factor - kunitz domain fusion proteins as factor viia inhibitors
TR199701121T1 (xx) Benazepril veya benazeprilat ve valsartan i�eren kombinasyon bile�imleri.
WO1998009668A3 (fr) Inhibiteurs de la synthese de la phosphatidylcholine
ATE218872T1 (de) Verfahren zur erhöhung der therapeutischen wirkung von nsaids und dazu verwendbare zwitterionische phospholipidhaltige zusammensetungen
WO1991012026A1 (fr) Procede servant a reduire les phenomenes post-operatoires d'adhesions entre tissus
WO2001005356A3 (fr) Produit de surveillance de poids a base d'un melange synergique d'extrait de guggul, de sel de phosphate et un stimulant metabolique
WO2006125970A3 (fr) Phospholipides a utiliser pour traiter un trouble inflammatoire allergique
CA2093133A1 (fr) Surfactant synthetique du poumon

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: C1

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: C1

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

WR Later publication of a revised version of an international search report
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 09424153

Country of ref document: US

NENP Non-entry into the national phase in:

Ref country code: JP

Ref document number: 1999500724

Format of ref document f/p: F

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase in:

Ref country code: CA

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载