+

WO1998051345A3 - Methode permettant de chasser les leucocytes infiltres dans un tissu - Google Patents

Methode permettant de chasser les leucocytes infiltres dans un tissu Download PDF

Info

Publication number
WO1998051345A3
WO1998051345A3 PCT/IB1998/000860 IB9800860W WO9851345A3 WO 1998051345 A3 WO1998051345 A3 WO 1998051345A3 IB 9800860 W IB9800860 W IB 9800860W WO 9851345 A3 WO9851345 A3 WO 9851345A3
Authority
WO
WIPO (PCT)
Prior art keywords
tissue
infiltrated
leukocytes
dislodging
infiltrated leukocytes
Prior art date
Application number
PCT/IB1998/000860
Other languages
English (en)
Other versions
WO1998051345A2 (fr
Inventor
Bosco M C Chan
Bhagirath Singh
Original Assignee
Robarts John P Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robarts John P Res Inst filed Critical Robarts John P Res Inst
Priority to AU73487/98A priority Critical patent/AU7348798A/en
Publication of WO1998051345A2 publication Critical patent/WO1998051345A2/fr
Publication of WO1998051345A3 publication Critical patent/WO1998051345A3/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2806Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne une méthode qui permet de diminuer le nombre de leucocytes infiltrant les tissus. Cette méthode peut être utilisée pour diminuer le nombre de leucocytes qui infiltrent un greffon après une greffe ou bien un tissu cible chez un individu atteint d'une maladie auto-immune. Elle peut également être employée pour identifier des molécules de la surface cellulaire impliquées dans la production et la persistance des leucocytes infiltrant les tissus.
PCT/IB1998/000860 1997-05-09 1998-05-08 Methode permettant de chasser les leucocytes infiltres dans un tissu WO1998051345A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU73487/98A AU7348798A (en) 1997-05-09 1998-05-08 Method for dislodging infiltrated leukocytes from a tissue

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4603697P 1997-05-09 1997-05-09
US60/046,036 1997-05-09

Publications (2)

Publication Number Publication Date
WO1998051345A2 WO1998051345A2 (fr) 1998-11-19
WO1998051345A3 true WO1998051345A3 (fr) 1999-03-04

Family

ID=21941235

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB1998/000860 WO1998051345A2 (fr) 1997-05-09 1998-05-08 Methode permettant de chasser les leucocytes infiltres dans un tissu

Country Status (2)

Country Link
AU (1) AU7348798A (fr)
WO (1) WO1998051345A2 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995019790A1 (fr) * 1994-01-25 1995-07-27 Athena Neurosciences, Inc. Anticorps humanises diriges contre la molecule d'adhesion leucocytaire vla-4
WO1996024673A1 (fr) * 1995-02-10 1996-08-15 Leukosite, Inc. Adressines vasculaires de muqueuses et leurs utilisations
WO1997025351A2 (fr) * 1996-01-04 1997-07-17 Leukosite, Inc. INHIBITEURS D'INTERACTIONS INDUITES PAR MAdCAM-1 ET PROCEDE D'UTILISATION DE CEUX-CI

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995019790A1 (fr) * 1994-01-25 1995-07-27 Athena Neurosciences, Inc. Anticorps humanises diriges contre la molecule d'adhesion leucocytaire vla-4
WO1996024673A1 (fr) * 1995-02-10 1996-08-15 Leukosite, Inc. Adressines vasculaires de muqueuses et leurs utilisations
WO1997025351A2 (fr) * 1996-01-04 1997-07-17 Leukosite, Inc. INHIBITEURS D'INTERACTIONS INDUITES PAR MAdCAM-1 ET PROCEDE D'UTILISATION DE CEUX-CI

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
AMARTEY J K ET AL: "The Effect of Antibodies Against Cell-Surface Adhesion Molecules (LFA-1alpha and ICAM-1) on the Migration and Localization of Tc -Labeled Leukocytes in Acute Infection", NUCLEAR MEDICINE AND BIOLOGY, vol. 24, no. 6, August 1997 (1997-08-01), pages 603-605, XP004089535 *
BERLIN P J ET AL: "MONOCLONAL ANTIBODIES AGAINST HUMAN T CELL ADHESION MOLECULES MODULATION OF IMMUNE FUNCTION IN NONHUMAN PRIMATES.", TRANSPLANTATION (BALTIMORE) 53 (4). 1992. 840-849. CODEN: TRPLAU ISSN: 0041-1337, XP002078067 *
CARRENO M P ET AL: "[Cell adhesion molecules and the immune system]. Les molecules d'adhesion et le syst eme immunitaire.", ALLERGIE ET IMMUNOLOGIE, vol. 27, no. 4, April 1995 (1995-04-01), pages 106 - 110, XP002078019 *
TANAKA, YOSHITAKA ET AL: "Inhibition of inflammatory liver injury by a monoclonal antibody against lymphocyte function-associated antigen-1", J. IMMUNOL. (1993), 151 5088-95 CODEN: JOIMA3;ISSN: 0022-1767, XP002078020 *

Also Published As

Publication number Publication date
WO1998051345A2 (fr) 1998-11-19
AU7348798A (en) 1998-12-08

Similar Documents

Publication Publication Date Title
EP1295952A3 (fr) Méthodes de criblage de peptides effecteurs transdominantes et des molécules ARN
EP0858039A3 (fr) Microprocesseur
DE69839437D1 (de) Aus der embryonalhülle hergestellte transplantate, verfahren zur abtrennung, derkonservierung und verwendung solcher transplantate in der chirurgie
ZA983496B (en) Methods for processing activated protein C.
HK1044588A1 (en) Method and kit for extracting prion protein.
NO984369D0 (no) Immunmodulering ved Õ anvende B7-bindende og CD40-bindende molkyler
EP1591789A3 (fr) Procédés permettant une meilleure récuperation de Troponine I et T
AU1575097A (en) Penetration hardness tester
PL346653A1 (en) Methods, instruments and materials for chondrocyte cell transplantation
JP2000500033A5 (fr)
ZA99452B (en) Antibodies against human IL-12.
JP2000500051A5 (fr)
JP2002515968A5 (fr)
JP2000500019A5 (fr)
EP0861592A3 (fr) Dispositif clarificatoir pour aquarium
JP2000500044A5 (fr)
ZA9811026B (en) Selective B3 adrenergic agonists.
JP2000500069A5 (fr)
JP2000500088A5 (fr)
JP2000500089A5 (fr)
WO1998051345A3 (fr) Methode permettant de chasser les leucocytes infiltres dans un tissu
EP1117675A4 (fr) Proteine-1 d'asymetrie analogue a la cadherine, et ses procedes d'utilisation
AU2927299A (en) Method for extracting polyamide particles
EP1032821A4 (fr) Procedes d'identification des interactions de macromolecules biologiques avec des composes
AU1170000A (en) Messaging platform

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

AK Designated states

Kind code of ref document: A3

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT GH

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
NENP Non-entry into the national phase

Ref country code: JP

Ref document number: 1998548986

Format of ref document f/p: F

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: CA

点击 这是indexloc提供的php浏览器服务,不要输入任何密码和下载