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WO1997028840A1 - Dispositif d'expansion de tissus prostatiques - Google Patents

Dispositif d'expansion de tissus prostatiques Download PDF

Info

Publication number
WO1997028840A1
WO1997028840A1 PCT/US1996/002500 US9602500W WO9728840A1 WO 1997028840 A1 WO1997028840 A1 WO 1997028840A1 US 9602500 W US9602500 W US 9602500W WO 9728840 A1 WO9728840 A1 WO 9728840A1
Authority
WO
WIPO (PCT)
Prior art keywords
balloon
catheter
tissue
expander
prostatic
Prior art date
Application number
PCT/US1996/002500
Other languages
English (en)
Inventor
Christopher J. Conway
Terance M. Fogarty
Original Assignee
Mentor Urology, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mentor Urology, Inc. filed Critical Mentor Urology, Inc.
Priority to CA002246434A priority Critical patent/CA2246434A1/fr
Priority to PCT/US1996/002500 priority patent/WO1997028840A1/fr
Priority to EP96908513A priority patent/EP0883417A1/fr
Priority to JP09528472A priority patent/JP2001500023A/ja
Priority to AU51732/96A priority patent/AU5173296A/en
Publication of WO1997028840A1 publication Critical patent/WO1997028840A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M2025/1043—Balloon catheters with special features or adapted for special applications
    • A61M2025/1075—Balloon catheters with special features or adapted for special applications having a balloon composed of several layers, e.g. by coating or embedding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/1018—Balloon inflating or inflation-control devices
    • A61M25/10181—Means for forcing inflation fluid into the balloon
    • A61M25/10183—Compressible bulbs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/1018—Balloon inflating or inflation-control devices
    • A61M25/10184—Means for controlling or monitoring inflation or deflation
    • A61M25/10185—Valves
    • A61M25/10186—One-way valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/1018—Balloon inflating or inflation-control devices
    • A61M25/10184—Means for controlling or monitoring inflation or deflation
    • A61M25/10187—Indicators for the level of inflation or deflation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M29/00—Dilators with or without means for introducing media, e.g. remedies
    • A61M29/02—Dilators made of swellable material

Definitions

  • This invention relates to medical tissue expansion, and more particularly it pertains to a prostatic tissue expander balloon catheter for expanding the prostatic urethra over a period of time. Inflation balloon pressure is maintained by valves in the inflation lumens. The tissue expander catheter is used to expand the prostatic urethra for the treatment of BPH (Benign Prostatic Hypertrophy).
  • BPH Breast Prostatic Hypertrophy
  • the sheath enclosed catheter of the dilator is inserted into the urethra.
  • the balloons are moved out of the sheath and into working position with the locating balloon in the bulbous urethra, resting against the external sphincter. Positioning is accomplished by palpation, fluoroscopy or by placing a rod lens along side of the PTFE sheath and looking through the transparent locating balloon to confirm diat the dilation balloon is in the proper location.
  • the dilation balloon is inflated up to 60 PSI for 10 to 15 minutes, after which both balloons are deflated. The catheter is then drawn back into the sheath and removed.
  • Another known device is the Dowd catheter manufactured by Mic ovasive, Inc., which also has a non-distensible dilation balloon measuring 30mm in diameter and 85mm in length.
  • a palpation nodule is mounted proximal of the balloon near the proximal end of the shaft.
  • a knob is affixed to the shaft to provide a means of maintaining the position of the balloon during inflation.
  • the Dowd catheter is manually inserted without benefit of introducers or otiier sheaths. Throughout the entire procedure, the physician has a finger in the rectum against the nodule to judge positioning of the catheter.
  • the balloon is inflated up to 60 PSI for the duration of the 10 to 15 minute procedure. During this time d e urologist must maintain traction of the shaft to prevent the balloon from migrating into the bladder. The balloon is removed following deflation by twisting and pulling.
  • Distensible balloons as suggested for use in this invention increase in size in proportion to the inflation pressure and shrink or constrict approximately to their original shape upon deflation; non-distensible balloons as used in the prior art are of fixed surface area (the envelope does not readily shrink on deflation) and can cause trauma upon removal.
  • Figure 2c is a cross-sectional view of the 2b valve taken along line 2c-2c in Figure 2b
  • Figure 3 illustrates a cross-sectional view of the catheter shaft taken along line 3-3 of Figure 1 ;
  • Figure 11 shows a syringe with pressure indicator for use with the pump of Figure 9.
  • the preferred prostatic tissue expander of this invention as illustrated in Figure 1 includes two inflatable balloons: A first positioning balloon, preferably a Foley balloon, located at the distal tip and a second balloon, a distensible tissue expansion balloon, located proximal of the first balloon.
  • a first positioning balloon preferably a Foley balloon, located at the distal tip and a second balloon
  • a distensible tissue expansion balloon located proximal of the first balloon.
  • the tissue expansion balloon will be available in a range of lengths and sizes for each patient. Being distensible, the diameter of the tissue expansion balloon increases as internal pressure is raised by inflation.
  • the catheter shaft upon which the balloons are mounted is of a flexible material and may be reinforced in the region of the tissue expansion balloon to prevent occlusion of the catheter lumens, if required.
  • the catheter shaft of this embodiment is equipped with two lumens to connect the balloons to pressure retaining valves located at the proximal end of the device.
  • a center lumen is also provided having a proximal connector to attach to a urine collection device, such as a leg bag.
  • Insertion of the device into the urethra is similar to the procedure used with a standard Foley catheter: The shaft is lubricated and manually inserted until the distal tip is in the bladder. The positioning balloon is inflated and mild traction is appli d while the tissue expansion balloon is partially inflated. With both balloons inflated, the device is anchored in place. Since no part of the second balloon is in the bladder, there is no tendency of the device to migrate into the bladder. Inflation of the second balloon may be increased gradually over a period of days or weeks to effect tissue expansion. After the expansion reaches a desired level, the balloon may be left in place while the prostate adjusts to the increased size of the urethra and establishes tissue stability. Upon completion of the treatment, the balloons are deflated and returned to their original diameter, approximately that of the device shaft. The device is then withdrawn from the urethra.
  • An inflation syringe generally indicated at 32 may be used to inflate the Foley balloon 16 as shown and the distensible tissue expander balloon 18 by connection to the proper inflation port 22 as shown or 26 by means of, for example, Luer fittings. Such fittings are well known in the art.
  • Proximal end 21 includes a branched body 34 having a central urine drainage lumen 36 flanked by lumens 38 and 40, all of which extend longitudinally through the catheter shaft 12 of Figure 1.
  • Urine drainage lumen 36 is a requisite feature of the device since the device is in place over a period of time extending from days to weeks and provision must be made for urination during that extended time.
  • Valvcs 24 and 28 are shown in a preferred construction in Figures 2b and 2a, respectively and in 2c.
  • Valve 24 is shown with a standard tapered Leur fitting by means of which the syringe pump of Figure 1 is attached to port 22, as is known in the art. Because the attachment is of relatively short duration, this arrangement is considered to be satisfactory although not critical.
  • valve 28 includes a hub fitting 29, another standard Leur fitting known in the art, because a pump ( as will be described further hereinbelow) is attached to port 26 for long term association with the device.
  • the two valves 24 and 28 are essentially identical and include the same elements, all of which are preferably formed of any suitable thermoplastic. Many specific materials will be readily apparent to those familiar with the medical device art, including materials other than thermoplastics.
  • Both valves include valve bodies 31, a retainer 33 which holds the valve body in place as shown in the respective branch of body 34.
  • Valve bodies 31 respectively define the inflation ports 22 or 26 and contain a flexible multi-fingered valve actuator retainer 35 and valve actuator rod 43.
  • Actuator rod 43 seats against seat 45 to normally close the valve and is held in place normally by actuator retainer 35 as shown.
  • Figure 3 illustrates in cross-sectional view the lumened catheter shaft 12 taken along line 3-3 of Figure 1 where all numerals correspond to those elements previously described. Illustrated in particular are the inflation lumens 38 and 40 flanking the central urine drainage lumen 36. The inflated distensible tissue expander balloon 18 and the positioning balloon 16 at the distal end 14 of the prostatic tissue expander 10 is illustrated in Figure 4 where all numerals correspond to those elements previously described.
  • FIG. 5 the cross-section is taken longitudinally and parallel to line 5-5 of Figure 1 in which the positioning balloon 16 and the distensible tissue expander balloon 18 are slightly expanded and in which all numerals correspond to those elements previously described.
  • Figure 6 the cross-section is taken along line 6-6 in Figure 5 of the partially inflated - 10- distcnsiblc tissue expander balloon 18 of Figure 5 in which all numerals correspond to those elements previously described.
  • Figure 7 the cross-section is taken along line 7-7 of the partially inflated Foley balloon 16 of Figure 5 where all numerals correspond to those elements previously described.
  • Illustrated in particular is a reinforcement tube 50 located in the urine lumen 36.
  • the positioning balloon 16 (preferably the Foley type) and distensible tissue expander balloon 18 arc shown bonded to or otherwise suitably secured around and about the lumened catheter shaft 12 in communication with their respective balloon ports 44 and 48.
  • Inflation lumen 38 is ported to the interior 42 of the positioning balloon 16 by port 44.
  • Inflation lumen 40 is ported to the interior 46 of the distensible tissue expander balloon 18 by port 48.
  • Optional reinforcement tubes 50 and 52 having interior lumen passageways 50a and 52a respectively, are located and suitably secured in the urine lumen 36 within the Foley balloon 16 and the distensible tissue expander balloon 18, respectively. These may be of a higher modulus elastomer, a thermoplastic or metal.
  • a locating nodule 62 as earlier referred to may be included on catheter shaft 12 as shown in Figure 5 and as is known in the art.
  • one basic embodiment of the invention comprises the following elements:
  • the proximal end of the catheter shaft 12 terminates at the urine drainage funnel end portion 37 and the branched funnels 39 and 41 connected to the minor catheter lumens 38 and 40.
  • the urine drainage funnel 37 is preferably the central funnel end portion because it connects to the major lumen 36.
  • the funnel length is about 25-60 mm long and is preferably cylindrical, conical or a combination thereof.
  • An appropriate connector joins the drainage funnel to a urine collection device (not shown).
  • the material used for the funnel is preferably the same as the catheter shaft.
  • Inflation funnels 39 and 41 and valves 24 and 28 for positioning and expander balloons 16 and 18 The branched funnels 39 and 41 , preferably cylindrical, 1 are used to connect the minor lumens 38 and 40 to the inflation valves 24 and 28.
  • the tissue expander device may include a hydrophilic surface which is bonded to the catheter shaft and balloons.
  • a prophylactic antibiotic may be inco ⁇ orated in the hydrophilic surface.
  • the antibiotic may be applied by the physician who would soak the expander in an antibiotic solution before placing it in the patient.
  • hydrophilic (Hydrogel) materials are listed:
  • PV ⁇ Poly Vinyl Alcohol
  • Hydrophilic Copolymers are:
  • Copolymerization of hydrogels affords the opportunity to tailor the properties such as water content, processing characteristics, and physical properties in die unhydrated state.
  • the time release characteristics for the release of antibiotics may also be tailored with copolymerization of the hydrogel surface component.
  • the following are examples of antibiotics which have obtained acceptance in the treatment of urinary tract infections, which may be incorporated into a hydrophilic surface:
  • the physician can determine if the nodule 62 is at the apex of the prostate, which indicates correct sizing of the expander. While maintaining gentle traction on the positioning balloon, the expander balloon 18 is inflated. To fill the expander the physician uses a syringe with sterile fluid and engages it to the Luer fitting on the check valve 28 for the expander balloon. The syringe is equipped with a pressure gauge to indicate the intraluminal pressure of the expander balloon. Fluid should be introduced into the expander and withdrawn several times, with the external sphincter positioned superior to the prostate, to evacuate any air. The physician then inflates the expander to recommended pressure; checks the fit of the expander after inflation by palpating the locating nodule 62; and disengages the syringe which closes the expander balloon check valve

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)
  • External Artificial Organs (AREA)

Abstract

Dispositif d'expansion de tissus prostatiques et procédé de traitement de l'hypertrophie prostatique bénigne, faisant appel à un cathéter souple comportant un ballonnet d'expansion de tissus se prêtant à une distension, un ballonnet de Foley gonflable à l'extrémité distale, un passage destiné aux urines, des passages de gonflage de ballonnets et des clapets aux extrémités desdits passages permettant de maintenir les ballonnets à l'état gonflé.
PCT/US1996/002500 1996-02-12 1996-02-12 Dispositif d'expansion de tissus prostatiques WO1997028840A1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA002246434A CA2246434A1 (fr) 1996-02-12 1996-02-12 Dispositif d'expansion de tissus prostatiques
PCT/US1996/002500 WO1997028840A1 (fr) 1996-02-12 1996-02-12 Dispositif d'expansion de tissus prostatiques
EP96908513A EP0883417A1 (fr) 1996-02-12 1996-02-12 Dispositif d'expansion de tissus prostatiques
JP09528472A JP2001500023A (ja) 1996-02-12 1996-02-12 前立腺組織イクスパンダー
AU51732/96A AU5173296A (en) 1996-02-12 1996-02-12 Prostatic tissue expander

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1996/002500 WO1997028840A1 (fr) 1996-02-12 1996-02-12 Dispositif d'expansion de tissus prostatiques

Publications (1)

Publication Number Publication Date
WO1997028840A1 true WO1997028840A1 (fr) 1997-08-14

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PCT/US1996/002500 WO1997028840A1 (fr) 1996-02-12 1996-02-12 Dispositif d'expansion de tissus prostatiques

Country Status (5)

Country Link
EP (1) EP0883417A1 (fr)
JP (1) JP2001500023A (fr)
AU (1) AU5173296A (fr)
CA (1) CA2246434A1 (fr)
WO (1) WO1997028840A1 (fr)

Cited By (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000025848A3 (fr) * 1998-11-02 2000-10-05 Mentor Corp Expansion de tissu prostatique
WO2001089619A1 (fr) * 2000-05-26 2001-11-29 Wallsten Medical S.A. Catheter a ballonnet
WO2001076514A3 (fr) * 2000-04-05 2002-05-02 Kyphon Inc Methodes et dispositifs destines au traitement d'os fractures et/ou malades
US6440127B2 (en) 1998-02-11 2002-08-27 Cosman Company, Inc. Method for performing intraurethral radio-frequency urethral enlargement
JP2002538888A (ja) * 1999-03-15 2002-11-19 イノベイションズ インコーポレーテッド 膀胱内バルーン
US6517534B1 (en) 1998-02-11 2003-02-11 Cosman Company, Inc. Peri-urethral ablation
US6743226B2 (en) 2001-02-09 2004-06-01 Cosman Company, Inc. Adjustable trans-urethral radio-frequency ablation
US6899719B2 (en) 1994-01-26 2005-05-31 Kyphon Inc. Systems and methods for treating fractured or diseased bone using expandable bodies
US7153306B2 (en) 2000-10-25 2006-12-26 Kyphon Inc. Systems and methods for reducing fractured bone using a fracture reduction cannula
US7815649B2 (en) 2000-04-07 2010-10-19 Kyphon SÀRL Insertion devices and method of use
US8092480B2 (en) 2000-04-07 2012-01-10 Kyphon Sarl Platform cannula for guiding the expansion of expandable bodies and method of use
US8425489B2 (en) 2009-05-08 2013-04-23 Medela Holding Ag Drainage tube device and coupling unit
WO2017049823A1 (fr) * 2015-09-21 2017-03-30 北京优尼康通医疗科技有限公司 Cathéter de dilatation de la prostate
WO2018204782A1 (fr) * 2017-05-05 2018-11-08 Urotronic, Inc. Cathéters à ballonnet revêtus de médicament pour lumières corporelles
US10173039B2 (en) 2013-11-11 2019-01-08 Yong Chul Ahn Balloon catheter
US20190015640A1 (en) * 2012-10-26 2019-01-17 Urotronic, Inc. Drug-coated balloon catheters for body lumens
US20190015639A1 (en) * 2012-10-26 2019-01-17 Urotronic, Inc. Drug-coated balloon catheters for body lumens
US10433928B2 (en) 2015-03-10 2019-10-08 Allergan Pharmaceuticals Holdings (Ireland) Unlimited Company Multiple needle injector
USD865950S1 (en) 2017-03-24 2019-11-05 Allergan, Inc. Syringe device
US10596321B2 (en) 2016-04-08 2020-03-24 Allergan, Inc. Aspiration and injection device
US10668188B2 (en) 2012-10-26 2020-06-02 Urotronic, Inc. Drug coated balloon catheters for nonvascular strictures
US10772755B2 (en) 2003-09-09 2020-09-15 Convatec Technologies Inc. Fecal management appliance and method and apparatus for introducing same
US10792427B2 (en) 2014-05-13 2020-10-06 Allergan, Inc. High force injection devices
US10850076B2 (en) 2012-10-26 2020-12-01 Urotronic, Inc. Balloon catheters for body lumens
US10888640B2 (en) 2015-04-24 2021-01-12 Urotronic, Inc. Drug coated balloon catheters for nonvascular strictures
US10898700B2 (en) 2012-10-26 2021-01-26 Urotronic, Inc. Balloon catheters for body lumens
US11185641B2 (en) 2014-10-01 2021-11-30 Allergan, Inc. Devices for injection and dosing
CN114748768A (zh) * 2021-09-13 2022-07-15 王江河 一种气囊式扩张导管
US11504450B2 (en) 2012-10-26 2022-11-22 Urotronic, Inc. Drug-coated balloon catheters for body lumens
US11684719B2 (en) 2013-05-23 2023-06-27 Allergan, Inc. Methods of treatment using a syringe extrusion accessory
US11730864B2 (en) 2015-04-24 2023-08-22 Urotronic, Inc. Drug coated balloon catheters for nonvascular strictures
WO2024006067A1 (fr) * 2022-06-28 2024-01-04 Growth Armor, LLC Dispositifs de dilatation améliorés incorporant des caractéristiques améliorées
US11938287B2 (en) 2012-10-26 2024-03-26 Urotronic, Inc. Drug-coated balloon catheters for body lumens
US11957853B2 (en) 2019-02-22 2024-04-16 Urotronic, Inc. Drug-coated balloon catheters for body lumens
US11992668B2 (en) 2008-12-02 2024-05-28 Allergan, Inc. Injection device

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DE60326495D1 (de) 2003-08-21 2009-04-16 Tsukada Medical Res Co Ltd Intermittierendes selbsthaltendes harnröhren-katheterset
GB2448892B (en) 2007-05-01 2009-04-29 Jotillou Entpr Ltd Catheter
KR101481887B1 (ko) * 2013-03-27 2015-01-21 전북대학교산학협력단 삽입 가이드를 이용하는 카테터 및 카테터 삽입 방법
KR101487594B1 (ko) * 2013-03-27 2015-01-29 전북대학교산학협력단 전립선 치료용 벌룬 카테터
KR101610282B1 (ko) * 2013-11-11 2016-04-07 (주)쓰리에이엠 벌룬 카테터
KR20150136379A (ko) * 2014-05-27 2015-12-07 이제범 전립선 고정용 카테타
US11160960B2 (en) 2016-09-19 2021-11-02 Boston Scientific Scimed, Inc. Anastomotic drainage stent
WO2018119442A1 (fr) * 2016-12-22 2018-06-28 Applied Tissue Technologies Llc Dispositifs et procédés pour le traitement des plaies
KR102329622B1 (ko) * 2019-12-18 2021-11-22 충북대학교 산학협력단 와상 환자용 자동 배뇨 장치
KR20230002291U (ko) * 2022-05-25 2023-12-04 박종윤 두개의 풍선을 소유한 요도도뇨관과 요도스텐트용 밀대
CN116236676B (zh) * 2023-02-20 2024-07-23 中国医学科学院北京协和医院 用于泌尿外科腔镜手术的球囊扩展器

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US4932958A (en) * 1988-05-10 1990-06-12 American Medical Systems, Inc. Prostate balloon dilator
US5007897A (en) * 1989-05-30 1991-04-16 Kalb Irvin M Drug delivery catheter
US5002558A (en) * 1989-08-23 1991-03-26 The Beth Israel Hospital Association Adjustable urethral catheter and method for treating obstructive prostatism
EP0449472A1 (fr) * 1990-03-22 1991-10-02 Argomed Ltd Appareil pour thermothérapie localisée pour les mammifères
WO1992004934A1 (fr) * 1990-09-14 1992-04-02 American Medical Systems, Inc. Catheter d'hyperthermie et de dilatation combines
WO1992008512A1 (fr) * 1990-11-09 1992-05-29 Boston Scientific Corporation Ballonnet pour catheter a usage medical

Cited By (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6899719B2 (en) 1994-01-26 2005-05-31 Kyphon Inc. Systems and methods for treating fractured or diseased bone using expandable bodies
US7959638B2 (en) 1997-06-09 2011-06-14 Kyphon Sarl Methods and devices for treating bone after high velocity and/or trauma fracture
US6517534B1 (en) 1998-02-11 2003-02-11 Cosman Company, Inc. Peri-urethral ablation
US6692493B2 (en) 1998-02-11 2004-02-17 Cosman Company, Inc. Method for performing intraurethral radio-frequency urethral enlargement
US6440127B2 (en) 1998-02-11 2002-08-27 Cosman Company, Inc. Method for performing intraurethral radio-frequency urethral enlargement
US7927339B2 (en) 1998-08-14 2011-04-19 Kyphon Sarl Systems and methods for reducing fractured bone using a fracture reduction cannula with a side discharge port
US6726691B2 (en) 1998-08-14 2004-04-27 Kyphon Inc. Methods for treating fractured and/or diseased bone
US8454620B2 (en) 1998-08-14 2013-06-04 Kyphon Sarl Systems and methods for reducing fractured bone using a fracture reduction cannula with a side discharge port
WO2000025848A3 (fr) * 1998-11-02 2000-10-05 Mentor Corp Expansion de tissu prostatique
JP2002538888A (ja) * 1999-03-15 2002-11-19 イノベイションズ インコーポレーテッド 膀胱内バルーン
KR100717224B1 (ko) * 2000-04-05 2007-05-11 키폰 인크. 골절되거나 병든 뼈를 치료하는 방법 및 장치
WO2001076514A3 (fr) * 2000-04-05 2002-05-02 Kyphon Inc Methodes et dispositifs destines au traitement d'os fractures et/ou malades
US7815649B2 (en) 2000-04-07 2010-10-19 Kyphon SÀRL Insertion devices and method of use
US8092480B2 (en) 2000-04-07 2012-01-10 Kyphon Sarl Platform cannula for guiding the expansion of expandable bodies and method of use
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EP0883417A1 (fr) 1998-12-16
CA2246434A1 (fr) 1997-08-14
JP2001500023A (ja) 2001-01-09
AU5173296A (en) 1997-08-28

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