WO1997028255B1 - Lignees de cellules epitheliales immortalisees provenant de prostate d'origine humaine, clones correspondants et leurs applications s'agissant de recherche et de therapie du cancer de la prostate - Google Patents
Lignees de cellules epitheliales immortalisees provenant de prostate d'origine humaine, clones correspondants et leurs applications s'agissant de recherche et de therapie du cancer de la prostateInfo
- Publication number
- WO1997028255B1 WO1997028255B1 PCT/US1997/001430 US9701430W WO9728255B1 WO 1997028255 B1 WO1997028255 B1 WO 1997028255B1 US 9701430 W US9701430 W US 9701430W WO 9728255 B1 WO9728255 B1 WO 9728255B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- immortalized
- epithelial cell
- cell line
- prostate epithelial
- malignant
- Prior art date
Links
- 210000000064 prostate epithelial cell Anatomy 0.000 title claims abstract 27
- 206010060862 Prostate cancer Diseases 0.000 title claims abstract 3
- 208000000236 Prostatic Neoplasms Diseases 0.000 title claims abstract 3
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 230000003211 malignant effect Effects 0.000 claims abstract 21
- 210000004027 cell Anatomy 0.000 claims abstract 11
- 210000000349 chromosome Anatomy 0.000 claims 8
- 230000002163 immunogen Effects 0.000 claims 6
- 238000000034 method Methods 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 102000019034 Chemokines Human genes 0.000 claims 3
- 108010012236 Chemokines Proteins 0.000 claims 3
- 102000004127 Cytokines Human genes 0.000 claims 3
- 108090000695 Cytokines Proteins 0.000 claims 3
- 239000013256 coordination polymer Substances 0.000 claims 3
- 230000000139 costimulatory effect Effects 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 3
- 230000028993 immune response Effects 0.000 claims 3
- 239000002671 adjuvant Substances 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 229940030749 prostate cancer vaccine Drugs 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102100023057 Neurofilament light polypeptide Human genes 0.000 claims 1
- 230000003013 cytotoxicity Effects 0.000 claims 1
- 231100000135 cytotoxicity Toxicity 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000008348 humoral response Effects 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 230000017095 negative regulation of cell growth Effects 0.000 claims 1
- 108010090677 neurofilament protein L Proteins 0.000 claims 1
- 229940124606 potential therapeutic agent Drugs 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 230000004044 response Effects 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 abstract 2
- 206010061764 Chromosomal deletion Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000012512 characterization method Methods 0.000 abstract 1
- 210000002307 prostate Anatomy 0.000 abstract 1
Abstract
La présente invention se rapporte à des lignées de cellules épithéliales provenant de prostate adulte d'origine humaine, malignes et immortalisées ou de lignées cellulaires dérivées, utiles dans le diagnostic et le traitement du cancer de la prostate. Plus particulièrement, l'invention se rapporte à des lignées de cellules épithéliales provenant de prostate adulte d'origine humaine, malignes, immortalisées et clonées, destinées au diagnostic et au traitement du cancer de la prostate. La présente invention se rapporte en outre à la caractérisation desdites lignées cellulaires par analyse de suppressions chromosomiques spécifiques.
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002245099A CA2245099C (fr) | 1996-02-02 | 1997-01-30 | Lignees de cellules epitheliales immortalisees provenant de prostate d'origine humaine, clones correspondants et leurs applications s'agissant de recherche et de therapie du cancer de la prostate |
| AT97904061T ATE239781T1 (de) | 1996-02-02 | 1997-01-30 | Immortalisierte menschliche prostata- epithelzellen und klone und ihre verwendungen zur untersuchung und therapie von prostata-krebs |
| EP97904061A EP0877798B1 (fr) | 1996-02-02 | 1997-01-30 | Lignees de cellules epitheliales immortalisees provenant de prostate d'origine humaine, clones correspondants et leurs applications s'agissant de recherche et de therapie du cancer de la prostate |
| JP9527794A JP2000506379A (ja) | 1996-02-02 | 1997-01-30 | ヒト前立腺上皮不死細胞の細胞株およびクローンおよびそれらの研究および前立腺癌治療に対する応用 |
| US08/913,770 US6982168B1 (en) | 1996-02-02 | 1997-01-30 | Immortal human prostate epithelial cell lines and clones and their applications in the research and therapy of prostate cancer |
| DE69721731T DE69721731T2 (de) | 1996-02-02 | 1997-01-30 | Immortalisierte menschliche prostata-epithelzellen und klone und ihre verwendungen zur untersuchung und therapie von prostata-krebs |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1104296P | 1996-02-02 | 1996-02-02 | |
| US60/011,042 | 1996-02-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO1997028255A1 WO1997028255A1 (fr) | 1997-08-07 |
| WO1997028255B1 true WO1997028255B1 (fr) | 1997-09-18 |
Family
ID=21748614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US1997/001430 WO1997028255A1 (fr) | 1996-02-02 | 1997-01-30 | Lignees de cellules epitheliales immortalisees provenant de prostate d'origine humaine, clones correspondants et leurs applications s'agissant de recherche et de therapie du cancer de la prostate |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6982168B1 (fr) |
| EP (1) | EP0877798B1 (fr) |
| JP (2) | JP2000506379A (fr) |
| AT (1) | ATE239781T1 (fr) |
| AU (1) | AU755554B2 (fr) |
| CA (1) | CA2245099C (fr) |
| DE (1) | DE69721731T2 (fr) |
| WO (1) | WO1997028255A1 (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9827104D0 (en) * | 1998-12-10 | 1999-02-03 | Onyvax Ltd | New cancer treatments |
| GB9827102D0 (en) * | 1998-12-10 | 1999-02-03 | Onyvax Ltd | New cancer treatments |
| GB9827103D0 (en) | 1998-12-10 | 1999-02-03 | Onyvax Ltd | New cancer treatments |
| WO2000071156A2 (fr) * | 1999-05-21 | 2000-11-30 | Onyvax Limited | Nouvelles formulations vaccinales-3 |
| GB9911823D0 (en) * | 1999-05-21 | 1999-07-21 | Onyvax Ltd | New vaccine formulations |
| ATE259655T1 (de) * | 1999-05-21 | 2004-03-15 | Onyvax Ltd | Aus ganzen zellen bestehender krebs-impfstoff, enthaltend ko-kultivierte maligne und nicht- maligne zellen |
| US7303911B2 (en) | 2000-04-01 | 2007-12-04 | Onyvax Limited | Prostate cell lines |
| US20050019336A1 (en) | 2003-07-23 | 2005-01-27 | Dalgleish Angus George | Human prostate cell lines in cancer treatment |
| WO2005083060A1 (fr) | 2004-03-01 | 2005-09-09 | Kitakyushu Foundation For The Advancement Of Industry, Science And Technology | Lignées de cellules humaines servant à la production d'une protéine, fournies en choisissant des lignées ayant une teneur élevée en protéines intracellulaires et en les mutant avec des produits cancerigènes |
| WO2008013918A2 (fr) * | 2006-07-26 | 2008-01-31 | Myelin Repair Foundation, Inc. | Régulation du cycle cellulaire et différenciation |
| US8715732B2 (en) * | 2009-01-05 | 2014-05-06 | Cornell University | Nucleic acid hydrogel via rolling circle amplification |
| US20130219531A1 (en) * | 2011-08-19 | 2013-08-22 | Tuskegee University | Immortalized human prostate cell lines |
| WO2018119295A1 (fr) * | 2016-12-22 | 2018-06-28 | Ventana Medical Systems, Inc. | Procédé entièrement automatisé d'extraction d'acide nucléique destiné à des échantillons de tissu |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5443954A (en) | 1987-10-30 | 1995-08-22 | The United States Of America As Represented By The Department Of Health And Human Services | Immortalized non-tumorigenic human bronchial epithelial cell lines |
| US5026637A (en) | 1989-02-28 | 1991-06-25 | Herbert Soule | Immortal human mammary epithelial cell lines |
| GB9105532D0 (en) | 1991-03-15 | 1991-05-01 | Imutran Ltd | Antibody production |
| US5376542A (en) | 1992-04-27 | 1994-12-27 | Georgetown University | Method for producing immortalized cell lines using human papilluma virus genes |
| US5462870A (en) | 1993-04-23 | 1995-10-31 | Wayne State University | Human diploid salivary gland epithelial cell lines |
| US5610043A (en) | 1994-04-28 | 1997-03-11 | The United States Of America As Represented By The Department Of Health And Human Services | Human prostatic cell lines immortalized by adenovirus 12-simian virus 40 (AD12/SV40) hybrid virus |
| US5824488A (en) * | 1994-04-28 | 1998-10-20 | Board Of Trustees Operating Michigan State University | Immortalized and malignant human prostatic cell lines |
-
1997
- 1997-01-30 US US08/913,770 patent/US6982168B1/en not_active Expired - Fee Related
- 1997-01-30 DE DE69721731T patent/DE69721731T2/de not_active Expired - Lifetime
- 1997-01-30 EP EP97904061A patent/EP0877798B1/fr not_active Expired - Lifetime
- 1997-01-30 WO PCT/US1997/001430 patent/WO1997028255A1/fr active IP Right Grant
- 1997-01-30 JP JP9527794A patent/JP2000506379A/ja active Pending
- 1997-01-30 AT AT97904061T patent/ATE239781T1/de not_active IP Right Cessation
- 1997-01-30 CA CA002245099A patent/CA2245099C/fr not_active Expired - Fee Related
-
1998
- 1998-07-24 AU AU77493/98A patent/AU755554B2/en not_active Ceased
-
2005
- 2005-11-10 JP JP2005326161A patent/JP2006122052A/ja active Pending
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