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WO1997018902A1 - Distributeur de fluides protegeant ces derniers contre une contamination - Google Patents

Distributeur de fluides protegeant ces derniers contre une contamination Download PDF

Info

Publication number
WO1997018902A1
WO1997018902A1 PCT/EP1996/004356 EP9604356W WO9718902A1 WO 1997018902 A1 WO1997018902 A1 WO 1997018902A1 EP 9604356 W EP9604356 W EP 9604356W WO 9718902 A1 WO9718902 A1 WO 9718902A1
Authority
WO
WIPO (PCT)
Prior art keywords
fluid
air
sterilizing
dispensing device
germ
Prior art date
Application number
PCT/EP1996/004356
Other languages
German (de)
English (en)
Inventor
Günter Geimer
Original Assignee
Ursatec Verpackung-Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE29518284U external-priority patent/DE29518284U1/de
Application filed by Ursatec Verpackung-Gmbh filed Critical Ursatec Verpackung-Gmbh
Priority to DE59610157T priority Critical patent/DE59610157D1/de
Priority to US09/068,801 priority patent/US6053368A/en
Priority to EP96934570A priority patent/EP0861128B1/fr
Publication of WO1997018902A1 publication Critical patent/WO1997018902A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/04—Deformable containers producing the flow, e.g. squeeze bottles
    • B05B11/047—Deformable containers producing the flow, e.g. squeeze bottles characterised by the outlet or venting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0039—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means
    • B05B11/0044—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0039—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means
    • B05B11/0044—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means
    • B05B11/00444—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means with provision for filtering or cleaning the air flow drawn into the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0062—Outlet valves actuated by the pressure of the fluid to be sprayed
    • B05B11/0072—A valve member forming part of an outlet opening
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1001—Piston pumps

Definitions

  • the invention relates to dispensing devices for fluids in which air flows back to equalize pressure, according to the preamble of claim 1.
  • Dispensing devices of this type are fastened on a storage container for the fluid to be dispensed.
  • ambient air flows into the storage container.
  • the disadvantage of such dispensing devices is that the inflowing air is contaminated and thus contaminates the fluid in the storage container.
  • the fluid germs at the outlet opening through contact with the environment. This contamination can grow through the outlet path of the fluid into the reservoir to the reservoir fluid and contaminate it. Such contamination leads to spoilage and danger to the user in pharmaceuticals and cosmetics.
  • Preservatives have harmful effects for consumers regardless of the price level of the products. They are questionable substances and lead to undesirable side effects.
  • the invention has for its object to provide a device of the type mentioned above for multiple dispensing of fluids from a supply with a pressure equalization by air, which protects the supply fluid from contamination with nobody and thus can be dispensed with the use of preservatives.
  • Another object of the present invention is to provide a dispensing device for fluids which can be adapted to conventional storage containers and which can be produced inexpensively.
  • the present invention uses a fluid dispenser in which the fluid exit path is at least in part separate from the air entry path for the
  • Air that is to enter the storage vessel for pressure equalization is guided.
  • the air germs and fluid germs can be rendered ineffective separately from one another.
  • This has the advantage that different methods can be used for the disinfection of the fluid or the air, each of which can be adapted to the different needs.
  • the disinfection or germ reduction of the fluid takes place in the area of the outlet path of the fluid by oligodynamically active substances. Heavy metal and / or heavy metal alloys in metallic and / or ionic form can be used. The use of silver has proven to be particularly advantageous.
  • the disinfection or germ reduction of the fluid in the region of the exit path of the fluid has the effect that no germs from the one with the
  • Outlet opening coming into contact with the environment in the opposite direction of the flow of the fluid past the valve (for example through growth) into the storage container and that the aseptic fluid from the storage container is not contaminated with contaminated residual quantities (for example at the outlet opening) when it is being dispensed, and the microbiological quality thereby becomes unsafe for the consumer. Furthermore, growth of the germs at the outlet opening and in all areas of the dispensing device is prevented, in particular in the case of a pump or a valve.
  • the disinfection of the air flowing into the storage container for pressure equalization can furthermore be achieved by other methods which are matched to the airborne germs.
  • the air can be passed through a sterile filter on its entry path or can reach the storage container through permeation through a membrane located in the airway. In this way, the airborne germs can be effectively retained.
  • the air can be guided past absorbent or adsorbing materials on their entry path, which hold the airborne germs.
  • electrostatic forces can be used here.
  • air disinfection can also be achieved by means of oiigodynamically active substances which are arranged in the air inlet path. It is also important that these agents can be combined, e.g. germs are absorbed by agents that also have microbicidal properties.
  • Another advantage that results from the separate disinfection of the fluid and the air is that substances that are used for air disinfection do not come into contact with the fluid. This prevents any foreign substances from getting into the fluid and thus being supplied to the consumer.
  • the dispensing device can be a pump which is placed on a conventional storage container.
  • the fluid outlet and air inlet paths which are routed separately in at least one part, can be integrated in the pump.
  • the reservoir can be designed as a squeeze bottle for dispensing the fluid, in which case a valve is advantageously provided at the fluid outlet.
  • FIG. 1 shows an example of a dispensing device in which means for disinfecting the fluid and, separately therefrom, means for disinfecting the inflowing air are used.
  • FIG. 2 shows a further exemplary embodiment in which the storage container is designed as a squeeze bottle as the dispensing device.
  • a suction / pressure pump 2 is used as the dispensing device, the structure of which is explained with reference to the drawing.
  • the suction / pressure pump 2 is placed by means of the sealing ring 12 in a sealing manner on the fluid reservoir 1 which is only partially shown here.
  • a piston 3 with an axial pump channel 7 runs in the pressure cylinder 8.
  • the piston 3 is held by a spring 6 at a stop in its upper rest position.
  • the pressure chamber 4, which is connected to the axial pump channel 7, is located between the piston 3 and the ball valve 5.
  • the piston 3 has a smaller outer diameter than the inner diameter of the pressure cylinder 8, so that a gap 14 remains between the outer wall of the piston and the inner wall of the cylinder, which, however, is closed at the bottom by the circumferential sealing lip 9 of the piston.
  • the pressure cylinder 8 In the lower region of the pressure chamber 4, the pressure cylinder 8 has a section 10 with a larger inner diameter, in which the sealing lip 9 does not have a sealing effect.
  • An actuating element 20 placed on the piston 3 has a riser pipe 21 with a pressure relief valve 22 for dispensing the fluid through an outlet opening 23. In the upper rest position of the piston 3 shown in the drawing, the sealing lip 9 seals the pressure chamber 4 from the openings 13 to the fluid container 1.
  • the plunger 11 is firmly connected to the piston 3, the section 15 with a star-shaped cross section leaving a connection between the pressure chamber 4 and the pump channel 7 free. In the rest position of the pump, the plunger 11 is at a distance from the ball valve 5, so that it opens in the pressure chamber 4 with respect to the fluid container 1 when the pressure is high and closes when the pressure is low.
  • the path of the fluid from the fluid container 1 through the dispensing device 2 is shown schematically by the arrow beginning at 27. When the ball valve 5 is open, the fluid passes through it into the Pump channel 7 and passes through the open pressure relief valve 22 to the outlet opening
  • oiigodynamically active substances are arranged on the exit path of the fluid just described. So these substances can, for example, on the spring 6, the inner walls of the pump channel 7, in the pressure relief valve 22 or at the outlet opening
  • at least part of the circumference is between the piston 3 and the section 18 a gap 19.
  • means are provided in the area of the air inlet path which disinfect the air.
  • Such means are a sterile filter, a membrane through which the air passes through permeation, germ-absorbing or germ-adsorbing materials, oiigodynamically active or microbicidal substances and combinations thereof.
  • a sterile filter 25, through which the air must pass on its entry path, can be arranged in area 24.
  • the very narrow gap 19 is suitable, e.g. to attach metallic silver as an oiigodynamically effective substance.
  • the fluid is dispensed by means of a squeeze bottle 31.
  • the fluid is dispensed by squeezing the squeeze bottle 31 through the fluid outlet 29.
  • a valve 28 for example a check valve, is provided at the fluid outlet 29.
  • means for disinfecting or reducing the germs of the fluid are provided in the fluid-contacting parts.
  • the dispensing device of this exemplary embodiment has an air inlet 30 which is guided separately from the fluid outlet 29.
  • Means 32 for sterilizing, sterilizing or reducing the germs of the inflowing air are also provided at the air inlet 30.
  • a sterile filter 32 can be used for air disinfection, and substances such as silver, for example, which have an oligodynamic effect, can be used for germ reduction or disinfection of the fluid. It should be emphasized that the disinfection of the fluid is carried out separately from the disinfection of the air. This makes it possible to provide and selectively use various means for fluid or air disinfection.
  • the dispensing devices of these exemplary embodiments are designed in such a way that they can be adapted to any conventional storage bottles and various pump versions for vertical and horizontal dispensing can be converted with this system.
  • the fluid in the storage container is effectively protected against contamination in an inexpensive manner, so that preservatives can be dispensed with. Preservatives are questionable substances and lead to undesirable side effects.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

L'invention a pour objet un distributeur destiné à distribuer des fluides à partir d'un réservoir, distributeur dans lequel de l'air pénétre dans le réservoir (1) en vue d'équilibrer la pression lorsque le fluide est distribué. Dans un tel distributeur, il est prévu, dans la zone d'admission de l'air, des moyens de stérilisation et d'élimination ou de réduction des germes, de tels moyens étant également prévus, séparément de cette zone, au moins dans une partie de la sortie du fluide. On dispose ainsi d'un distributeur qui, d'une part, peut être adapté aux réservoirs et systèmes de remplissage classiques existants et, d'autre part, protège le fluide dans le réservoir de toute contamination, efficacement et économiquement, ce qui rend inutile l'emploi de conservateurs. Le distributeur peut se présenter sous la forme d'une pompe (2) ou peut être réalisé de façon que le réservoir soit une bouteille pressable (31).
PCT/EP1996/004356 1995-11-17 1996-10-08 Distributeur de fluides protegeant ces derniers contre une contamination WO1997018902A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE59610157T DE59610157D1 (de) 1995-11-17 1996-10-08 Vor kontamination schützende abgabevorrichtung für fluide
US09/068,801 US6053368A (en) 1995-11-17 1996-10-08 Anti-contamination dispensing apparatus for fluids
EP96934570A EP0861128B1 (fr) 1995-11-17 1996-10-08 Distributeur de fluides protegeant ces derniers contre une contamination

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19542959A DE19542959C1 (de) 1995-11-17 1995-11-17 Vor Kontamination schützende Abgabevorrichtung für Fluide
DE29518284U DE29518284U1 (de) 1995-11-17 1995-11-17 Vor Kontamination schützende Abgabevorrichtung für Fluide
DE19542959.1 1995-11-17
DE19609880.7 1996-03-13
DE19609880A DE19609880A1 (de) 1995-11-17 1996-03-13 Vor Kontamination schützende Abgabevorrichtung für Fluide

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US09/009,721 Continuation US6187528B1 (en) 1995-07-18 1998-01-20 Photothermographic recording material coatable from an acqueous medium

Publications (1)

Publication Number Publication Date
WO1997018902A1 true WO1997018902A1 (fr) 1997-05-29

Family

ID=26020453

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1996/004356 WO1997018902A1 (fr) 1995-11-17 1996-10-08 Distributeur de fluides protegeant ces derniers contre une contamination

Country Status (2)

Country Link
DE (2) DE19542959C1 (fr)
WO (1) WO1997018902A1 (fr)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000024444A1 (fr) * 1998-10-27 2000-05-04 Webb Garth T Dispositif de vaporisation pour administrer des medicaments steriles
GB2344857A (en) * 1998-12-15 2000-06-21 Bespak Plc Pump dispenser ventilation filter
WO2001017690A1 (fr) 1999-09-09 2001-03-15 Valois S.A. Pompe de distribution de produit fluide amelioree, et dispositif de distribution de produit fluide comportant une telle pompe
WO2002034411A1 (fr) * 2000-10-28 2002-05-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Atomiseur destine a des liquides
WO2003002265A1 (fr) * 2001-06-29 2003-01-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg Nebuliseurs servant a appliquer des liquides sur la surface oculaire ou sur le tissu conjonctif de l'oeil
JP2003502361A (ja) * 1999-06-22 2003-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 安定なキシロメタゾリン及びオキシメタゾリン溶液
WO2004052434A1 (fr) 2002-12-07 2004-06-24 Boehringer Ingelheim Pharma Gmbh & Co.Kg Atomiseur de liquides
DE102004044344A1 (de) * 2004-09-09 2006-03-30 Ing. Erich Pfeiffer Gmbh Dosiervorrichtung
JP2008515630A (ja) * 2004-10-13 2008-05-15 インジ エリッヒ プファイファ ゲーエムベーハ 配量装置
DE102010048986A1 (de) 2010-10-20 2012-04-26 Ursapharm Arzneimittel Gmbh Dosierpumpe
EP3103498A1 (fr) * 2015-06-12 2016-12-14 AP Pharma Systems Atomizadores e Dispensadores Ltda Distributeur par pulvérisation de médicaments par voie nasale

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2307478A1 (fr) * 2000-05-03 2001-11-03 Garth T. Webb Distributeur antimicrobien
AT413028B (de) * 2004-04-05 2005-10-15 Kuehtreiber Franz Verfahren und vorrichtung zur weitgehenden keimfreihaltung von abfüllvorrichtungen
DE102008001312B4 (de) * 2008-04-22 2015-03-05 Hpt Hochwertige Pharmatechnik Gmbh & Co. Kg Mehrkomponentenverpackungs- und Spendersystem
DE102014221393A1 (de) * 2014-10-21 2016-04-21 F. Holzer Gmbh Pumpkopf für eine Dosiervorrichtung, Dosiervorrichtung sowie Verwendungsmöglichkeiten

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5154325A (en) * 1991-01-09 1992-10-13 Ryder International Corporation Solution delivery nozzle and system with antimicrobial features
US5232687A (en) * 1990-08-29 1993-08-03 Ursapharm Arzneimittel Gmbh Fluid dispenser for germ-free fluid
WO1994011115A1 (fr) * 1992-11-11 1994-05-26 Tee Enterprises Limited Atomiseur

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5232687A (en) * 1990-08-29 1993-08-03 Ursapharm Arzneimittel Gmbh Fluid dispenser for germ-free fluid
US5154325A (en) * 1991-01-09 1992-10-13 Ryder International Corporation Solution delivery nozzle and system with antimicrobial features
WO1994011115A1 (fr) * 1992-11-11 1994-05-26 Tee Enterprises Limited Atomiseur

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000024444A1 (fr) * 1998-10-27 2000-05-04 Webb Garth T Dispositif de vaporisation pour administrer des medicaments steriles
US6745763B2 (en) * 1998-10-27 2004-06-08 Garth T. Webb Vaporizing device for administering sterile medication
US6237814B1 (en) 1998-12-15 2001-05-29 Bespak Plc Relating to dispensing apparatus
GB2344857B (en) * 1998-12-15 2001-03-14 Bespak Plc Improvements in or relating to dispensing apparatus
GB2344857A (en) * 1998-12-15 2000-06-21 Bespak Plc Pump dispenser ventilation filter
JP2003502361A (ja) * 1999-06-22 2003-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 安定なキシロメタゾリン及びオキシメタゾリン溶液
WO2001017690A1 (fr) 1999-09-09 2001-03-15 Valois S.A. Pompe de distribution de produit fluide amelioree, et dispositif de distribution de produit fluide comportant une telle pompe
WO2002034411A1 (fr) * 2000-10-28 2002-05-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Atomiseur destine a des liquides
WO2003002265A1 (fr) * 2001-06-29 2003-01-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg Nebuliseurs servant a appliquer des liquides sur la surface oculaire ou sur le tissu conjonctif de l'oeil
WO2004052434A1 (fr) 2002-12-07 2004-06-24 Boehringer Ingelheim Pharma Gmbh & Co.Kg Atomiseur de liquides
DE102004044344A1 (de) * 2004-09-09 2006-03-30 Ing. Erich Pfeiffer Gmbh Dosiervorrichtung
JP2008515630A (ja) * 2004-10-13 2008-05-15 インジ エリッヒ プファイファ ゲーエムベーハ 配量装置
DE102010048986A1 (de) 2010-10-20 2012-04-26 Ursapharm Arzneimittel Gmbh Dosierpumpe
WO2012052174A1 (fr) 2010-10-20 2012-04-26 Ursapharm Arzneimittel Gmbh Pompe de dosage
EP3103498A1 (fr) * 2015-06-12 2016-12-14 AP Pharma Systems Atomizadores e Dispensadores Ltda Distributeur par pulvérisation de médicaments par voie nasale
WO2016198931A1 (fr) * 2015-06-12 2016-12-15 Ap Pharma Systems Atomizadores E Dispensadores Ltda Pulvérisateur pour médicaments par voie nasale
AU2016275311B2 (en) * 2015-06-12 2021-02-25 Ap Pharma Systems Atomizadores E Dispensadores Ltda Spray dispenser for nasal drugs
US11224702B2 (en) 2015-06-12 2022-01-18 Ap Pharma Systems Atomizadores E Dispensadores Ltda Spray dispenser for nasal drugs

Also Published As

Publication number Publication date
DE19609880A1 (de) 1997-09-18
DE19542959C1 (de) 1996-10-24

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