+

WO1997014783B1 - Reparation osseuse par modification tissulaire faisant appel a des cellules periostiques cultivees - Google Patents

Reparation osseuse par modification tissulaire faisant appel a des cellules periostiques cultivees

Info

Publication number
WO1997014783B1
WO1997014783B1 PCT/US1996/016664 US9616664W WO9714783B1 WO 1997014783 B1 WO1997014783 B1 WO 1997014783B1 US 9616664 W US9616664 W US 9616664W WO 9714783 B1 WO9714783 B1 WO 9714783B1
Authority
WO
WIPO (PCT)
Prior art keywords
cells
matrix
composition
periosteal
bone
Prior art date
Application number
PCT/US1996/016664
Other languages
English (en)
Other versions
WO1997014783A1 (fr
Filing date
Publication date
Priority claimed from US08/545,988 external-priority patent/US5700289A/en
Application filed filed Critical
Priority to AU74515/96A priority Critical patent/AU7451596A/en
Priority to EP96936643A priority patent/EP0862617A1/fr
Publication of WO1997014783A1 publication Critical patent/WO1997014783A1/fr
Publication of WO1997014783B1 publication Critical patent/WO1997014783B1/fr

Links

Abstract

Il a été démontré que des cellules périostiques mises en culture avaient un phénotype ostéoblastique, avec production d'ostéocalcine et de mucopolysaccharides. Il a également été démontré qu'après avoir été ensemencées dans des implants polymères, elles réparaient des lacunes crâniennes d'une taille critique, et cette réparation a été confirmée par histologie, dosages biochimiques et radiodensitométrie.
PCT/US1996/016664 1995-10-20 1996-10-17 Reparation osseuse par modification tissulaire faisant appel a des cellules periostiques cultivees WO1997014783A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU74515/96A AU7451596A (en) 1995-10-20 1996-10-17 Tissue-engineered bone repair using cultured periosteal cells
EP96936643A EP0862617A1 (fr) 1995-10-20 1996-10-17 Reparation osseuse par modification tissulaire faisant appel a des cellules periostiques cultivees

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US545,988 1990-06-28
US08/545,988 US5700289A (en) 1995-10-20 1995-10-20 Tissue-engineered bone repair using cultured periosteal cells

Publications (2)

Publication Number Publication Date
WO1997014783A1 WO1997014783A1 (fr) 1997-04-24
WO1997014783B1 true WO1997014783B1 (fr) 1997-05-22

Family

ID=24178377

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/016664 WO1997014783A1 (fr) 1995-10-20 1996-10-17 Reparation osseuse par modification tissulaire faisant appel a des cellules periostiques cultivees

Country Status (4)

Country Link
US (1) US5700289A (fr)
EP (1) EP0862617A1 (fr)
AU (1) AU7451596A (fr)
WO (1) WO1997014783A1 (fr)

Families Citing this family (130)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030077825A1 (en) * 1994-07-22 2003-04-24 Bhatnagar Rajendra S. Structures useful for bone engineering and methods
US7968110B2 (en) * 1992-02-11 2011-06-28 Merz Aesthetics, Inc. Tissue augmentation material and method
US6537574B1 (en) * 1992-02-11 2003-03-25 Bioform, Inc. Soft tissue augmentation material
US7060287B1 (en) * 1992-02-11 2006-06-13 Bioform Inc. Tissue augmentation material and method
US6541037B1 (en) 1995-05-19 2003-04-01 Etex Corporation Delivery vehicle
US5676976A (en) 1995-05-19 1997-10-14 Etex Corporation Synthesis of reactive amorphous calcium phosphates
US6287341B1 (en) 1995-05-19 2001-09-11 Etex Corporation Orthopedic and dental ceramic implants
US6132463A (en) * 1995-05-19 2000-10-17 Etex Corporation Cell seeding of ceramic compositions
US6027742A (en) * 1995-05-19 2000-02-22 Etex Corporation Bioresorbable ceramic composites
US5824084A (en) * 1996-07-03 1998-10-20 The Cleveland Clinic Foundation Method of preparing a composite bone graft
DE19630034A1 (de) * 1996-07-25 1998-04-23 Huels Chemische Werke Ag Biohybrides Zahnimplantat
US6953594B2 (en) 1996-10-10 2005-10-11 Etex Corporation Method of preparing a poorly crystalline calcium phosphate and methods of its use
AU734691B2 (en) 1996-10-16 2001-06-21 Life Science Enterprises, Inc. Bioceramic compositions
US7517539B1 (en) 1996-10-16 2009-04-14 Etex Corporation Method of preparing a poorly crystalline calcium phosphate and methods of its use
US8728536B2 (en) 1996-10-16 2014-05-20 Etex Corporation Chemotherapeutic composition using nanocrystalline calcium phosphate paste
US5866415A (en) * 1997-03-25 1999-02-02 Villeneuve; Peter E. Materials for healing cartilage and bone defects
US5981826A (en) * 1997-05-05 1999-11-09 Georgia Tech Research Corporation Poly(vinyl alcohol) cryogel
US20030008396A1 (en) * 1999-03-17 2003-01-09 Ku David N. Poly(vinyl alcohol) hydrogel
US6077987A (en) 1997-09-04 2000-06-20 North Shore-Long Island Jewish Research Institute Genetic engineering of cells to enhance healing and tissue regeneration
DE19803673A1 (de) 1998-01-30 1999-08-05 Norbert M Dr Meenen Biohybrider Gelenkflächenersatz
EP1053002A1 (fr) * 1998-02-10 2000-11-22 Oregon Health Sciences University Traitement de malformations osseuses avec des cellules precurseurs osteoblastiques
US7019192B2 (en) * 1998-02-27 2006-03-28 Musculoskeletal Transplant Foundation Composition for filling bone defects
US6821462B2 (en) * 1998-07-10 2004-11-23 Jeneric/Pentron, Inc. Mass production of shells and models for dental restorations produced by solid free-form fabrication methods
US6322728B1 (en) 1998-07-10 2001-11-27 Jeneric/Pentron, Inc. Mass production of dental restorations by solid free-form fabrication methods
US6808659B2 (en) * 1998-07-10 2004-10-26 Jeneric/Pentron Incorporated Solid free-form fabrication methods for the production of dental restorations
US20050023710A1 (en) * 1998-07-10 2005-02-03 Dmitri Brodkin Solid free-form fabrication methods for the production of dental restorations
US6551355B1 (en) * 1998-08-14 2003-04-22 Cambridge Scientific, Inc. Tissue transplant coated with biocompatible biodegradable polymer
US6197061B1 (en) * 1999-03-01 2001-03-06 Koichi Masuda In vitro production of transplantable cartilage tissue cohesive cartilage produced thereby, and method for the surgical repair of cartilage damage
US6143030A (en) * 1999-03-26 2000-11-07 Bristol-Myers Squibb Co. Impaction allograft form and method of orthopaedic surgery using same
US7371408B1 (en) 1999-06-07 2008-05-13 Wright Medical Technology, Inc. Bone graft substitute composition
FR2794982B1 (fr) * 1999-06-15 2001-08-03 Depuy Bioland Materiau de greffe osseuse forme d'une ceramique phosphocalcique et de tissu osseux
US6521431B1 (en) * 1999-06-22 2003-02-18 Access Pharmaceuticals, Inc. Biodegradable cross-linkers having a polyacid connected to reactive groups for cross-linking polymer filaments
US6303138B1 (en) * 1999-09-17 2001-10-16 Depuy Orthopaedics Endothelin-based compositions for enhancing connective tissue repair
US7186419B2 (en) * 2000-08-25 2007-03-06 Contura Sa Polyacrylamide hydrogel for arthritis
MY130475A (en) * 2000-08-25 2007-06-29 Contura As Polyacrylamide hydrogel and its use as an endoprosthesis
WO2002030481A1 (fr) * 2000-10-10 2002-04-18 Massachusetts Institute Of Technology Liberation de cellules utilisant des structures gel en maille degradables de maniere controlable
US7175336B2 (en) 2001-01-26 2007-02-13 Depuy Acromed, Inc. Graft delivery system
US6723131B2 (en) 2001-02-28 2004-04-20 The Cleveland Clinic Foundation Composite bone marrow graft material with method and kit
DE60228477D1 (de) * 2001-05-08 2008-10-02 Darwin Molecular Corp Verfahren zur regulierung der immunfunktion in primaten unter verwendung des foxp3-proteins
EP1433487A1 (fr) * 2001-08-22 2004-06-30 National Institute of Advanced Industrial Science and Technology Procede de regeneration osseuse
CN1296393C (zh) * 2001-08-25 2007-01-24 康特拉有限公司 均质聚合物制备的温度控制方法
US7371409B2 (en) 2001-09-06 2008-05-13 Wright Medical Technology, Inc. Bone graft substitute composition
EP1435980A4 (fr) * 2001-09-15 2006-06-07 Univ California Tissu cartilagineux stratifie et son procede de fabrication
US20030165473A1 (en) * 2001-11-09 2003-09-04 Rush-Presbyterian-St. Luke's Medical Center Engineered intervertebral disc tissue
EP1499267A4 (fr) * 2002-02-05 2008-10-29 Depuy Mitek Inc Compositions osteoconductrices bioresorbables destinees a la regeneration osseuse
US8293530B2 (en) * 2006-10-17 2012-10-23 Carnegie Mellon University Method and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
US8529956B2 (en) 2002-03-18 2013-09-10 Carnell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
WO2003079985A2 (fr) * 2002-03-18 2003-10-02 Carnegie Mellon University Procede et appareil permettant de preparer un squelette biomimetique
EP1489998B1 (fr) 2002-03-29 2010-12-08 Wright Medical Technology, Inc. Composition de remplacement pour une greffe osseuse
US20060204544A1 (en) * 2002-05-20 2006-09-14 Musculoskeletal Transplant Foundation Allograft bone composition having a gelatin binder
US8187326B2 (en) * 2002-05-22 2012-05-29 Advanced Technologies And Regenerative Medicine, Llc. Attachment of absorbable tissue scaffolds to fixation devices
US6652887B1 (en) 2002-06-24 2003-11-25 Wright Medical Technology, Inc. Bone graft substitute composition
US7291179B2 (en) * 2002-06-24 2007-11-06 Wright Medical Technology, Inc. Bone graft substitute composition
US7745532B2 (en) * 2002-08-02 2010-06-29 Cambridge Polymer Group, Inc. Systems and methods for controlling and forming polymer gels
WO2005017000A1 (fr) * 2003-07-31 2005-02-24 Cambridge Polymer Group Systemes et procedes permettant de controler et de former des gels polymeres
KR100539371B1 (ko) * 2002-10-21 2005-12-27 메디칸(주) 인체 세포의 체외배양 방법
US7507257B2 (en) * 2003-02-04 2009-03-24 Wright Medical Technology, Inc. Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects
JP5189763B2 (ja) 2003-04-11 2013-04-24 エテックス コーポレーション 骨誘導性骨材料
US6905723B2 (en) * 2003-05-30 2005-06-14 Depuy Products, Inc. Strontium-substituted apatite coating
US7067169B2 (en) * 2003-06-04 2006-06-27 Chemat Technology Inc. Coated implants and methods of coating
US7375077B2 (en) * 2003-09-19 2008-05-20 The Board Of Trustees Of The University Of Illinois In vivo synthesis of connective tissues
WO2005077304A1 (fr) 2004-02-06 2005-08-25 Georgia Tech Research Corporation Dispositif biocompatible porteur
AU2005213499B2 (en) 2004-02-06 2010-09-02 Georgia Tech Research Corporation Surface directed cellular attachment
US8216359B2 (en) 2004-04-15 2012-07-10 Etex Corporation Delayed-setting calcium phosphate pastes
US20050278025A1 (en) * 2004-06-10 2005-12-15 Salumedica Llc Meniscus prosthesis
US8512730B2 (en) * 2004-07-12 2013-08-20 Isto Technologies, Inc. Methods of tissue repair and compositions therefor
EP1773299B1 (fr) * 2004-07-12 2017-07-05 Isto Technologies Inc. Systeme de matrice tissulaire
US7250550B2 (en) 2004-10-22 2007-07-31 Wright Medical Technology, Inc. Synthetic bone substitute material
US9981063B2 (en) * 2004-11-24 2018-05-29 Mayo Foundation For Medical Education And Research Biosynthetic composite for osteochondral defect repair
US20060293236A1 (en) * 2005-06-23 2006-12-28 Prescott Albert G Injectable Osteogenic Formula and Method of Using Same
DK1933892T3 (da) 2005-09-09 2013-03-25 Agnovos Healthcare Llc Sammensat knoglegrafterstatningscement og artikler fremstillet deraf
US8025903B2 (en) 2005-09-09 2011-09-27 Wright Medical Technology, Inc. Composite bone graft substitute cement and articles produced therefrom
TWI274591B (en) * 2005-11-07 2007-03-01 Univ Tsinghua Composite scaffold for remedying articular cartilage tissue and preparation thereof
AU2006315629B2 (en) 2005-11-14 2012-04-19 Biomet 3I, Llc Deposition of discrete nanoparticles on an implant surface
US8147860B2 (en) 2005-12-06 2012-04-03 Etex Corporation Porous calcium phosphate bone material
JP2009518132A (ja) * 2005-12-07 2009-05-07 イスト・テクノロジーズ・インコーポレイテッド 軟骨修復方法
US20070184087A1 (en) 2006-02-06 2007-08-09 Bioform Medical, Inc. Polysaccharide compositions for use in tissue augmentation
US8529959B2 (en) 2006-10-17 2013-09-10 Carmell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
US7935363B2 (en) * 2006-12-12 2011-05-03 Synthasome, Inc. Composite material for tissue repair
US9045735B2 (en) * 2007-04-03 2015-06-02 The Cleveland Clinic Foundation Enrichment of tissue-derived adult stem cells based on retained extracellular matrix material
EP2211753A1 (fr) 2007-09-27 2010-08-04 3M Innovative Properties Company Formation numérique d'un modèle dentaire pour la fabrication d'appareils de laboratoire orthodontiques
WO2009085781A1 (fr) * 2007-12-21 2009-07-09 3M Innovative Properties Company Procédés de préparation d'un modèle de dentition virtuel et fabrication d'un appareil dentaire d'après celui-ci
ES2545781T3 (es) 2008-01-28 2015-09-15 Biomet 3I, Llc Implante superficial con mayor hidrofilia
US8293813B2 (en) * 2008-03-05 2012-10-23 Biomet Manufacturing Corporation Cohesive and compression resistant demineralized bone carrier matrix
DK2299926T3 (da) 2008-06-26 2020-03-02 3M Innovative Properties Co Fremgangsmåde til fremstilling af en overførselsbakke til ortodontiske anordninger
US20100055078A1 (en) * 2008-08-15 2010-03-04 The Government of the U.S.A, as represented by the Department of Veterans Affairs Methods of making a transplantable bone repair system using multipotent stem cells
CN101347641A (zh) * 2008-09-04 2009-01-21 崔福斋 羟基磷灰石陶瓷脊柱融合器
AU2010314992B2 (en) 2009-11-09 2016-09-15 Spotlight Technology Partners Llc Polysaccharide based hydrogels
CN107033368A (zh) 2009-11-09 2017-08-11 聚光灯技术合伙有限责任公司 碎裂水凝胶
US8641418B2 (en) 2010-03-29 2014-02-04 Biomet 3I, Llc Titanium nano-scale etching on an implant surface
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8895291B2 (en) 2010-10-08 2014-11-25 Terumo Bct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
WO2012129234A1 (fr) 2011-03-21 2012-09-27 Endo Pharmaceuticals Inc. Dispositif et procédé d'anastomose urétrale
US8834928B1 (en) 2011-05-16 2014-09-16 Musculoskeletal Transplant Foundation Tissue-derived tissugenic implants, and methods of fabricating and using same
CA3048443C (fr) 2011-05-26 2021-01-05 Cartiva, Inc. Implant d'articulation conique et outils associes
ES2671740T3 (es) 2012-03-20 2018-06-08 Biomet 3I, Llc Superficie de tratamiento para una superficie de implante
US10207027B2 (en) 2012-06-11 2019-02-19 Globus Medical, Inc. Bioactive bone graft substitutes
US20150245839A1 (en) 2012-09-18 2015-09-03 Endo Pharmaceuticals Inc. Urethral anastomosis device and method
US10245306B2 (en) 2012-11-16 2019-04-02 Isto Technologies Ii, Llc Flexible tissue matrix and methods for joint repair
US8873041B1 (en) 2013-01-29 2014-10-28 Bayspec, Inc. Raman spectroscopy using multiple excitation wavelengths
CA2905721A1 (fr) 2013-03-14 2014-10-02 Endo Pharmaceuticals Inc. Dispositif d'anastomose uretrale
US9486483B2 (en) 2013-10-18 2016-11-08 Globus Medical, Inc. Bone grafts including osteogenic stem cells, and methods relating to the same
US9539286B2 (en) 2013-10-18 2017-01-10 Globus Medical, Inc. Bone grafts including osteogenic stem cells, and methods relating to the same
CN105992816B (zh) 2013-11-16 2018-04-17 泰尔茂比司特公司 生物反应器中的细胞扩增
US9579421B2 (en) 2014-02-07 2017-02-28 Globus Medical Inc. Bone grafts and methods of making and using bone grafts
US9463264B2 (en) 2014-02-11 2016-10-11 Globus Medical, Inc. Bone grafts and methods of making and using bone grafts
EP3613841B1 (fr) 2014-03-25 2022-04-20 Terumo BCT, Inc. Remplacement passif de supports
US9907882B2 (en) * 2014-04-18 2018-03-06 Warsaw Orthopedic, Inc. Demineralized bone matrix with improved osteoinductivity
CN106715676A (zh) 2014-09-26 2017-05-24 泰尔茂比司特公司 按计划供养
US10179191B2 (en) 2014-10-09 2019-01-15 Isto Technologies Ii, Llc Flexible tissue matrix and methods for joint repair
EP3753531A1 (fr) 2015-03-31 2020-12-23 Cartiva, Inc. Implants d'hydrogel avec des matériaux poreux
EP3892241A1 (fr) 2015-03-31 2021-10-13 Cartiva, Inc. Foret pour implant carpométacarpien
EP3282961A4 (fr) 2015-04-14 2018-12-05 Cartiva, Inc. Outillage pour création d'une ouverture conique dans le tissu et procédés associés
WO2016187413A1 (fr) 2015-05-21 2016-11-24 Musculoskeletal Transplant Foundation Fibres osseuses corticales déminéralisées modifiées
US10016529B2 (en) 2015-06-10 2018-07-10 Globus Medical, Inc. Biomaterial compositions, implants, and methods of making the same
US11426489B2 (en) 2015-06-10 2022-08-30 Globus Medical, Inc. Biomaterial compositions, implants, and methods of making the same
WO2017004592A1 (fr) 2015-07-02 2017-01-05 Terumo Bct, Inc. Croissance cellulaire à l'aide de stimuli mécaniques
CN109415696A (zh) 2016-05-25 2019-03-01 泰尔茂比司特公司 细胞扩增
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11702634B2 (en) 2017-03-31 2023-07-18 Terumo Bct, Inc. Expanding cells in a bioreactor
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
WO2021105878A1 (fr) 2019-11-26 2021-06-03 3M Innovative Properties Company Gabarit dentaire pour la liaison directe d'appareils orthodontiques et procédés de fabrication et d'utilisation de celui-ci
US20230157792A1 (en) 2020-04-24 2023-05-25 3M Innovative Properties Company An indirect bonding tray for bonding orthodontic appliances and methods of making and using the same
US11896736B2 (en) 2020-07-13 2024-02-13 Globus Medical, Inc Biomaterial implants and methods of making the same
GB2619893A (en) 2021-03-23 2023-12-20 Terumo Bct Inc Cell capture and expansion
US12152699B2 (en) 2022-02-28 2024-11-26 Terumo Bct, Inc. Multiple-tube pinch valve assembly

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL74617A (en) * 1985-03-15 1988-11-15 Yeda Res & Dev Compositions comprising a vitamin d derivative and method for the local treatment of bone fractures in animals
US5171310A (en) * 1989-07-17 1992-12-15 Chisena Ernest C Method and apparatus for treating fractures of long bones
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5197985A (en) * 1990-11-16 1993-03-30 Caplan Arnold I Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells
US5226914A (en) * 1990-11-16 1993-07-13 Caplan Arnold I Method for treating connective tissue disorders
GB9125052D0 (en) * 1991-11-26 1992-01-22 Isis Innovation Culture of bone cells
US5324294A (en) * 1992-10-15 1994-06-28 Dental Marketing Specialists Bone augmentation method and apparatus
US5439951A (en) * 1993-03-24 1995-08-08 Children's Medical Center Corporation Isolation of the calcium-phosphate crystals of bone
US5565502A (en) * 1993-03-24 1996-10-15 Children's Medical Center Corporation Isolation of the calcium-phosphate crystals of bone
CN1104257C (zh) * 1993-03-29 2003-04-02 津莫吉尼蒂克斯公司 含pdgf和维生素d的刺激成骨细胞生长的组合物
US5518680A (en) * 1993-10-18 1996-05-21 Massachusetts Institute Of Technology Tissue regeneration matrices by solid free form fabrication techniques

Similar Documents

Publication Publication Date Title
WO1997014783B1 (fr) Reparation osseuse par modification tissulaire faisant appel a des cellules periostiques cultivees
US5648301A (en) Bioactive material template for in vitro synthesis of bone tissue
Du et al. Three‐dimensional nano‐HAp/collagen matrix loading with osteogenic cells in organ culture
US6413538B1 (en) Bioactive glass or ceramic substrates having bound cell adhesion molecules
AU2009212946B2 (en) Autologous cells on a support matrix for tissue repair
Ecarot-Charrier et al. Mineralization in osteoblast cultures: a light and electron microscopic study
Ducheyne et al. Effect of bioadctive glass templates on osteoblast proliferation and in vitro synthesis of bone‐like tissue
Vehof et al. Influence of rhBMP-2 on rat bone marrow stromal cells cultured on titanium fiber mesh
EP1165830A4 (fr) Cellules souches et reseaux derives de tissus adipeux
Fricain et al. Evaluation of proliferation and protein expression of human bone marrow cells cultured on coral crystallized in the aragonite or calcite form
Weissenböck et al. Particle size of hydroxyapatite granules calcified from red algae affects the osteogenic potential of human mesenchymal stem cells in vitro
Masquelier et al. Morphologic characterization of osteoblast-like cell cultures isolated from newborn rat calvaria
Petite et al. Adhesion, growth and differentiation of human bone marrow stromal cells on non-porous calcium carbonate and plastic substrata: effects of dexamethasone and 1, 25dihydroxyvitamin D3
Faucheux et al. Biocompatibility testing of a bovine hydroxy—apatite ceramic material with the use of osteo-progenitor cells isolated from human bone marrow
JP3650734B2 (ja) ヒト骨髄外脂肪組織細胞の骨芽細胞の分化を誘発する方法
EP1819290A2 (fr) Constructions sans echafaudage pour genie tissulaire de cartilage articulaire
Srouji et al. Microscopy analysis of bone marrow–derived osteoprogenitor cells cultured on hydrogel 3‐D scaffold
Al-Salihi et al. Bone marrow mesenchymal stem cells differentiation and proliferation on the surface of coral implant
US20050142660A1 (en) Conditioned medium for culturing Schwann cells
DE69531627T2 (de) Humane hypertrophe chrondrozyten zelllinien
Hosseini et al. Collagen fibres are not required for initial matrix mineralization by bone cells
Davies In vitro assessment of bone biocompatibility.
JP2000060542A (ja) 高密度細胞培養法
Teixeira et al. Chondrocyte maturation on biphasic calcium phosphate scaffold: A preliminary study
Bevens et al. Reconstruction of calvarial defects by bioresorbable glass ceramic: An experimental study in rats
点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载