WO1997013551B1 - Method and apparatus for improving the function of sensory cells - Google Patents
Method and apparatus for improving the function of sensory cellsInfo
- Publication number
- WO1997013551B1 WO1997013551B1 PCT/US1996/015632 US9615632W WO9713551B1 WO 1997013551 B1 WO1997013551 B1 WO 1997013551B1 US 9615632 W US9615632 W US 9615632W WO 9713551 B1 WO9713551 B1 WO 9713551B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cell area
- sensory cell
- sensory
- signal
- inputting
- Prior art date
Links
- 230000001953 sensory effect Effects 0.000 title claims abstract 74
- 210000004027 cell Anatomy 0.000 claims 61
- 210000003205 muscle Anatomy 0.000 claims 13
- 210000002435 tendon Anatomy 0.000 claims 12
- 210000005036 nerve Anatomy 0.000 claims 7
- 230000004936 stimulating effect Effects 0.000 claims 4
- 230000035807 sensation Effects 0.000 claims 3
- 210000004165 myocardium Anatomy 0.000 claims 2
- 230000000272 proprioceptive effect Effects 0.000 claims 2
- 210000002345 respiratory system Anatomy 0.000 claims 2
- 210000002265 sensory receptor cell Anatomy 0.000 claims 2
- 102000027509 sensory receptors Human genes 0.000 claims 2
- 108091008691 sensory receptors Proteins 0.000 claims 2
- 230000002463 transducing effect Effects 0.000 claims 2
- 210000001635 urinary tract Anatomy 0.000 claims 2
- 230000000007 visual effect Effects 0.000 claims 2
- 230000006870 function Effects 0.000 claims 1
- 230000000737 periodic effect Effects 0.000 claims 1
- 210000001044 sensory neuron Anatomy 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
Abstract
Method and system for enhancing the function of sensory cells are disclosed. The method comprises locating a sensory cell area associated with the sensory cell whose function is to be enhanced and inputting a bias signal to the sensory cell area. The apparatus comprises a signal processor for producing a bias signal and an input device for inputting the bias signal to a sensory cell area associated with a sensory cell whose function is to be enhanced. Inputting the bias signal to a sensory cell area effectively lowers the threshold of sensory cells with which the sensory cell area is associated.
Claims
1. Use of a system for effectively lowering the threshold of a threshold- based sensory cell, said system performing the steps of: a) locating an area of the body associated with a sensory cell area; c) generating a bias signal; and, c) inputting the bias signal to the located area wherein the bias signal causes the threshold of sensory cells in the sensory cell area to be exceeded in response to a subthreshold input stimulus thereby effectively lowering the threshold of the sensory cells in the sensory cell area.
2. Use of a system of claim 1 wherein the step of generating a bias signal further comprises the step of transducing a subthreshold input stimulus to the sensory cell area into an electrical signal and generating the bias signal in response to the electrical signal.
3. Use of a system of claim 1 wherein the located area comprises a nerve.
4. Use of a system of claim 1 wherein the located area comprises the sensory cell area.
5. Use of a system of claim 1 wherein the located area comprises a muscle.
6. Use of a system of claim 1 wherein the bias signal comprises a noise signal.
7. Use of a system of claim 1 wherein the bias signal comprises an electrical signal which is modulated in response to the subthreshold input stimulus.
8. Use of a system of claim 1 wherein the bias signal comprises a periodic signal.
9. Use of a system of claim 1 wherein the bias signal comprises a high frequency deterministic signal.
10. Use of a system of claim 1 wherein the bias signal comprises a magnetic field.
11. Use of a system of claim 10 wherein the magnetic field comprises a randomly fluctuating field intensity.
12. Use of a system of claim 1 wherein the bias signal comprises a mechanical stimulus.
13. Use of a system of claim 1 wherein the bias signal comprises a predetermined signal.
14. Use of a system of claim 10 wherein the predetermined signal is calibrated according to a function which the threshold-based sensory cell performs.
15. Use of a system for effectively lowering the threshold of a threshold- based sensory cell, said system performing the steps of: a) sensing a subthreshold input stimulus to a sensory cell area; b) generating an electrical signal in response to the subthreshold input stimulus; and c) inputting the electrical signal to the sensory cell area wherein the electrical signal causes the threshold of sensory cells in the sensory cell area to be exceeded thereby effectively lowering the threshold of the sensory cells in the sensory cell area.
16. Use of a system of claim 15 further comprising the step of: d) determining an optimal level for a parameter of the electrical signal, wherein the step of inputting an electrical signal comprises inputting an electrical signal having the parameter with the optimal level.
17. Use of a system of claim 16 wherein the parameter comprises frequency.
18. Use of a system of claim 16 wherein the parameter comprises amplitude.
19. Use of a system of claim 15 wherein the step of generating comprises generating a noise signal in response to the subthreshold input stimulus.
20. Use of a system of claim 15 wherein the step of generating comprises generating the electrical signal in response to the subthreshold input stimulus, and modulating the electrical signal in response to the subthreshold input stimulus.
21. Use of a system of claim 15 wherein the step of mputting comprises locating a sensory nerve associated with the sensory cell area, implanting a nerve cuff around the located sensory nerve and inputting the electrical signal through the implanted nerve cuff.
22. Use of a system of claim 15 wherein the step of inputting comprises locating a sensory nerve associated with the sensory cell area, positioning a surface electrode on the exterior ofthe body in an area associated with the sensory cell area and inputting the electrical signal through the surface electrode.
23. Use of a system of claim 15 wherein the step of inputting comprises locating the sensory cell area, implanting electrodes at the sensory cell area and inputting the electrical signal through the implanted electrodes.
24. Use of a system of claim 15 wherein the step of inputting comprises positioning a muscle stimulator in an area around a muscle associated with the sensory cell area and inputting the electrical signal through the muscle stimulator, wherein the muscle stimulator stimulates a muscle thereby stimulating the sensory cell with which the muscle is associated.
25. Use of a system of claim 24 wherein the muscle stimulator mechanically stimulates the muscle.
26. Use of a system of claim 15 wherein the step of inputting comprises positioning a tendon stimulator in an area around a tendon associated with the sensory cell area and inputting the electrical signal through the tendon stimulator, wherein the tendon stimulator stimulates a tendon thereby stimulating the sensory cell with which the tendon is associated.
27. Use of a system of claim 26 wherein the tendon stimulator mechanically stimulates the tendon.
28. Use of a system of claim 15 wherein the sensory cell area comprises one or more sensory neurons.
29. Use of a system of claim 15 wherein the sensory cell area comprises one or more sensory receptors.
30. Use of a system of claim 15 wherein the sensory cell area is associated with the proprioceptive system.
31. Use of a system of claim 15 wherein the sensory cell area is associated with the urinary tract.
32. Use of a system of claim 31 wherein the sensory cell area is associated with the bladder.
33. Use of a system of claim 15 wherein the sensory cell area is associated with the circulatory system.
34. Use of a system of claim 33 wherein the sensory cell area is associated with the heart muscle.
35. Use of a system of claim 15 wherein the sensory cell area is associated with the respiratory system.
36. Use of a system of claim 15 wherein the sensory cell area is associated with the auditory system.
37. Use of a system of claim 15 wherein the sensory cell area is associated with the visual system.
38. Use of a system of claim 15 wherein the sensory cell area is associated with the vibration-sensation system.
39. Use of a system of claim 15 wherein the sensory cell area is associated with the temperature-sensation system.
40. Use of a system of claim 15 wherein the sensory cell area is associated with the touch-pressure sensation system.
41. A system for effectively lowering the threshold of a sensory cell comprising; a signal processor for producing at least one bias signal; input means for inputting each bias signal to a sensory cell area associated with the sensory cell; and a controller for controlling the signal processor and input means; wherein the at least one bias signal causes the threshold of sensory cells in the sensory cell area to be exceeded thereby effectively lowering the threshold of said sensory cells.
42. The system of claim 41 further comprising a transducer for transducing an input stimulus to the sensory cell area into an electrical signal.
43. The system of claim 42 wherein the controller controls the transducer, signal processor and input device to operate in response to a subthreshold input stimulus.
44. The system of claim 43 wherein the controller modulates each bias signal in response to the subthreshold input stimulus.
45. The system of claim 41 wherein each bias signal is a non-modulated signal.
46. The system of claim 41 wherein the input means comprises a distributed array of input devices.
47. The system of claim 41 wherein the signal processor further comprises calibration means for determining an optimal level for a parameter of the bias signal.
48. The system of claim 47 wherein the parameter comprises frequency.
49. The system of claim 47 wherein the parameter comprises amplitude.
50. The system of claim 41 wherein the input means comprises at least one nerve cuff.
51. The system of claim 41 wherein the input means comprises at least one magnetic field stimulator.
52. The system of claim 41 wherein the input means comprises electrodes.
53. The system of claim 41 wherein the input means comprises at least one muscle stimulator, wherein each muscle stimulator stimulates a muscle thereby stimulating a sensory cell area with which the muscle is associated.
54. The system of claim 41 wherein the input means comprises a tendon stimulator, wherein each tendon stimulator stimulates a tendon thereby stimulating a sensory cell area with which the tendon is associated.
55. The system of claim 41 wherein the sensory cell area comprises one or more sensory cells.
56. The system of claim 41 wherein the sensory cell area comprises one or more sensory receptors.
57. The system of claim 41 wherein the sensory cell area is associated with the proprioceptive system.
58. The system of claim 41 wherein the sensory cell area is associated with the urinary tract.
59. The system of claim 58 wherein the sensory cell area is associated with the bladder.
60. The system of claim 41 wherein the sensory cell area is associated with the circulatory system.
61. The system of claim 60 wherein the sensory cell area is associated with the heart muscle.
62. The system of claim 41 wherein the sensory cell area is associated with the respiratory system.
63. The system of claim 41 wherein the sensory cell area is associated with the auditory system.
64. The system of claim 41 wherein the sensory cell area is associated with the visual system.
65. The system of claim 41 wherein the sensory cell area is associated with the vibration-sensation system.
66. The system of claim 41 wherein the sensory cell area is associated with the temperature sensation system.
67. The system of claim 41 wherein the sensory cell area is associated with the touch-pressure sensation system.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU73798/96A AU7379896A (en) | 1995-10-11 | 1996-09-30 | Method and apparatus for improving the function of sensory cells |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US534395P | 1995-10-11 | 1995-10-11 | |
| US60/005,343 | 1995-10-11 | ||
| US08/703,674 US5782873A (en) | 1995-10-11 | 1996-08-27 | Method and apparatus for improving the function of sensory cells |
| US08/703,674 | 1996-08-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO1997013551A1 WO1997013551A1 (en) | 1997-04-17 |
| WO1997013551B1 true WO1997013551B1 (en) | 1997-06-05 |
Family
ID=26674247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US1996/015632 WO1997013551A1 (en) | 1995-10-11 | 1996-09-30 | Method and apparatus for improving the function of sensory cells |
Country Status (3)
| Country | Link |
|---|---|
| US (2) | US5782873A (en) |
| AU (1) | AU7379896A (en) |
| WO (1) | WO1997013551A1 (en) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5782873A (en) * | 1995-10-11 | 1998-07-21 | Trustees Of Boston University | Method and apparatus for improving the function of sensory cells |
| US7167748B2 (en) * | 1996-01-08 | 2007-01-23 | Impulse Dynamics Nv | Electrical muscle controller |
| US8825152B2 (en) * | 1996-01-08 | 2014-09-02 | Impulse Dynamics, N.V. | Modulation of intracellular calcium concentration using non-excitatory electrical signals applied to the tissue |
| IL125424A0 (en) | 1998-07-20 | 1999-03-12 | New Technologies Sa Ysy Ltd | Pacing with hemodynamic enhancement |
| US8321013B2 (en) | 1996-01-08 | 2012-11-27 | Impulse Dynamics, N.V. | Electrical muscle controller and pacing with hemodynamic enhancement |
| IL148949A0 (en) * | 1996-01-08 | 2002-11-10 | Impulse Dynamics Nv | Electrical muscle controller |
| US9289618B1 (en) | 1996-01-08 | 2016-03-22 | Impulse Dynamics Nv | Electrical muscle controller |
| US9713723B2 (en) | 1996-01-11 | 2017-07-25 | Impulse Dynamics Nv | Signal delivery through the right ventricular septum |
| KR20020013496A (en) * | 1999-02-04 | 2002-02-20 | 추후제출 | Method and apparatus for maintenance and expansion of hemopoietic stem cells and(or) progenitor cells |
| WO2006073671A1 (en) | 2004-12-09 | 2006-07-13 | Impulse Dynamics Nv | Protein activity modification |
| US9101765B2 (en) | 1999-03-05 | 2015-08-11 | Metacure Limited | Non-immediate effects of therapy |
| US8666495B2 (en) * | 1999-03-05 | 2014-03-04 | Metacure Limited | Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar |
| US8019421B2 (en) | 1999-03-05 | 2011-09-13 | Metacure Limited | Blood glucose level control |
| US8700161B2 (en) * | 1999-03-05 | 2014-04-15 | Metacure Limited | Blood glucose level control |
| US8346363B2 (en) * | 1999-03-05 | 2013-01-01 | Metacure Limited | Blood glucose level control |
| US20040249421A1 (en) * | 2000-09-13 | 2004-12-09 | Impulse Dynamics Nv | Blood glucose level control |
| AU6951500A (en) | 1999-06-07 | 2000-12-28 | Johns Hopkins University, The | Cardiac shock electrode system and corresponding implantable defibrillator system |
| US7596409B2 (en) * | 1999-06-07 | 2009-09-29 | The Johns Hopkins University | Cardiac shock electrode system and corresponding implantable defibrillator system |
| US6560489B2 (en) * | 1999-08-24 | 2003-05-06 | Em Vascular, Inc. | Therapeutic device and method for treating diseases of cardiac muscle |
| US6556872B2 (en) | 1999-08-24 | 2003-04-29 | Ev Vascular, Inc. | Therapeutic device and method for treating diseases of cardiac muscle |
| US6993385B1 (en) * | 1999-10-25 | 2006-01-31 | Impulse Dynamics N.V. | Cardiac contractility modulation device having anti-arrhythmic capabilities and a method of operating thereof |
| US7027863B1 (en) | 1999-10-25 | 2006-04-11 | Impulse Dynamics N.V. | Device for cardiac therapy |
| WO2001030445A1 (en) | 1999-10-25 | 2001-05-03 | Impulse Dynamics N.V. | Cardiac contractility modulation device having anti-arrhythmic capabilities and a method of operating thereof |
| WO2001051122A1 (en) | 2000-01-07 | 2001-07-19 | Biowave Corporation | Electro therapy method and apparatus |
| US20080033492A1 (en) * | 2000-01-07 | 2008-02-07 | Biowave Corporation | Electro-therapy method |
| US7013179B2 (en) * | 2000-01-07 | 2006-03-14 | Biowave Corporation | Percutaneous electrode array |
| US7236831B2 (en) | 2000-07-13 | 2007-06-26 | Northstar Neuroscience, Inc. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
| US7672730B2 (en) * | 2001-03-08 | 2010-03-02 | Advanced Neuromodulation Systems, Inc. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
| US7146217B2 (en) | 2000-07-13 | 2006-12-05 | Northstar Neuroscience, Inc. | Methods and apparatus for effectuating a change in a neural-function of a patient |
| US7756584B2 (en) | 2000-07-13 | 2010-07-13 | Advanced Neuromodulation Systems, Inc. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
| US7024247B2 (en) | 2001-10-15 | 2006-04-04 | Northstar Neuroscience, Inc. | Systems and methods for reducing the likelihood of inducing collateral neural activity during neural stimulation threshold test procedures |
| US7831305B2 (en) | 2001-10-15 | 2010-11-09 | Advanced Neuromodulation Systems, Inc. | Neural stimulation system and method responsive to collateral neural activity |
| US7010351B2 (en) | 2000-07-13 | 2006-03-07 | Northstar Neuroscience, Inc. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
| US7305268B2 (en) | 2000-07-13 | 2007-12-04 | Northstar Neurscience, Inc. | Systems and methods for automatically optimizing stimulus parameters and electrode configurations for neuro-stimulators |
| US6829509B1 (en) * | 2001-02-20 | 2004-12-07 | Biophan Technologies, Inc. | Electromagnetic interference immune tissue invasive system |
| US7299096B2 (en) | 2001-03-08 | 2007-11-20 | Northstar Neuroscience, Inc. | System and method for treating Parkinson's Disease and other movement disorders |
| US20030130697A1 (en) * | 2001-10-23 | 2003-07-10 | Halperin Henry R. | System and/or method for refibrillation of the heart for treatment of post-countershock pulseless electrical activity and/or asystole |
| US7221981B2 (en) | 2002-03-28 | 2007-05-22 | Northstar Neuroscience, Inc. | Electrode geometries for efficient neural stimulation |
| US7033336B2 (en) * | 2002-03-29 | 2006-04-25 | Gore Enterprise Holdings, Inc. | Proximal catheter assembly having a relief valve |
| US20080077192A1 (en) * | 2002-05-03 | 2008-03-27 | Afferent Corporation | System and method for neuro-stimulation |
| EP1501588A1 (en) * | 2002-05-03 | 2005-02-02 | Afferent Corporation | A method and apparatus for enhancing neurophysiologic performance |
| US7236830B2 (en) | 2002-12-10 | 2007-06-26 | Northstar Neuroscience, Inc. | Systems and methods for enhancing or optimizing neural stimulation therapy for treating symptoms of Parkinson's disease and/or other movement disorders |
| US7302298B2 (en) | 2002-11-27 | 2007-11-27 | Northstar Neuroscience, Inc | Methods and systems employing intracranial electrodes for neurostimulation and/or electroencephalography |
| US20050075680A1 (en) | 2003-04-18 | 2005-04-07 | Lowry David Warren | Methods and systems for intracranial neurostimulation and/or sensing |
| AU2003297761A1 (en) | 2002-12-09 | 2004-06-30 | Northstar Neuroscience, Inc. | Methods for treating neurological language disorders |
| CN100538292C (en) * | 2003-02-10 | 2009-09-09 | N-特莱格有限公司 | The touch of Aristogrid detects |
| KR20050122205A (en) * | 2003-03-06 | 2005-12-28 | 애퍼런트 코퍼레이션 | Method and apparatus for improving human balance and gait and preventing foot injury |
| US11439815B2 (en) | 2003-03-10 | 2022-09-13 | Impulse Dynamics Nv | Protein activity modification |
| JP2006519663A (en) * | 2003-03-10 | 2006-08-31 | インパルス ダイナミックス エヌヴイ | Apparatus and method for delivering electrical signals for regulating gene expression in heart tissue |
| US20040218767A1 (en) * | 2003-04-24 | 2004-11-04 | Doman G. Alexander | Surround sound methods and apparatus for improving auditory processing and increasing spatial awareness |
| US7388378B2 (en) * | 2003-06-24 | 2008-06-17 | Medtronic, Inc. | Magnetic resonance imaging interference immune device |
| US8792985B2 (en) * | 2003-07-21 | 2014-07-29 | Metacure Limited | Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar |
| JP2007501067A (en) | 2003-08-01 | 2007-01-25 | ノーススター ニューロサイエンス インコーポレイテッド | Apparatus and method for applying neural stimulation to patient |
| US7020517B2 (en) * | 2004-02-20 | 2006-03-28 | Biophan Technologies, Inc. | Fibrillation/tachycardia monitoring and preventive system and methodology |
| WO2006119467A2 (en) * | 2005-05-04 | 2006-11-09 | Impulse Dynamics Nv | Protein activity modification |
| US11779768B2 (en) | 2004-03-10 | 2023-10-10 | Impulse Dynamics Nv | Protein activity modification |
| US8352031B2 (en) * | 2004-03-10 | 2013-01-08 | Impulse Dynamics Nv | Protein activity modification |
| EP1786510A4 (en) | 2004-07-15 | 2009-12-02 | Northstar Neuroscience Inc | Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy |
| US7565200B2 (en) | 2004-11-12 | 2009-07-21 | Advanced Neuromodulation Systems, Inc. | Systems and methods for selecting stimulation sites and applying treatment, including treatment of symptoms of Parkinson's disease, other movement disorders, and/or drug side effects |
| US9821158B2 (en) | 2005-02-17 | 2017-11-21 | Metacure Limited | Non-immediate effects of therapy |
| US8244371B2 (en) * | 2005-03-18 | 2012-08-14 | Metacure Limited | Pancreas lead |
| US8929991B2 (en) | 2005-10-19 | 2015-01-06 | Advanced Neuromodulation Systems, Inc. | Methods for establishing parameters for neural stimulation, including via performance of working memory tasks, and associated kits |
| US7729773B2 (en) | 2005-10-19 | 2010-06-01 | Advanced Neuromodualation Systems, Inc. | Neural stimulation and optical monitoring systems and methods |
| US9737703B2 (en) * | 2009-07-10 | 2017-08-22 | Boston Scientific Neuromodulation Corporation | Method to enhance afferent and efferent transmission using noise resonance |
| WO2011092710A2 (en) | 2010-02-01 | 2011-08-04 | Metacure Limited | Gastrointestinal electrical therapy |
| US10071015B2 (en) | 2013-04-18 | 2018-09-11 | Uwm Research Foundation, Inc. | Wearable device for improving tactile sensitivity |
| JP6483364B2 (en) | 2014-07-09 | 2019-03-13 | ユニバーシティ・オブ・タンペレＵｎｉｖｅｒｓｉｔｙ ｏｆ Ｔａｍｐｅｒｅ | Haptic device |
| JP6639771B2 (en) | 2014-07-09 | 2020-02-05 | ユニバーシティ・オブ・タンペレＵｎｉｖｅｒｓｉｔｙ ｏｆ Ｔａｍｐｅｒｅ | Tactile imaging system |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2051369B (en) * | 1979-05-16 | 1983-12-14 | Univ Bradford | Determining the response to hot and cold gas |
| US4503863A (en) * | 1979-06-29 | 1985-03-12 | Katims Jefferson J | Method and apparatus for transcutaneous electrical stimulation |
| US4554922A (en) * | 1982-09-30 | 1985-11-26 | Prystowsky Eric N | Method of inhibiting cardiac arrhythmias |
| US4632116A (en) * | 1984-06-29 | 1986-12-30 | Rosen Joseph M | Microelectronic axon processor |
| US4640286A (en) * | 1984-11-02 | 1987-02-03 | Staodynamics, Inc. | Optimized nerve fiber stimulation |
| DE3538662A1 (en) * | 1985-10-31 | 1987-05-07 | Johannes Dr Rer Nat Lensing | Stimulus generator for the neurophysiological stimulation of muscles, nerve paths and nerve cells through the skin and the skull cap |
| US4813399A (en) * | 1986-07-18 | 1989-03-21 | Gordon Robert T | Process for the treatment of neurological or neuromuscular diseases and development |
| US4881526A (en) * | 1988-05-27 | 1989-11-21 | Empi, Inc. | Intravaginal electrode and stimulation system for controlling female urinary incontinence |
| US5024223A (en) * | 1989-08-08 | 1991-06-18 | Chow Alan Y | Artificial retina device |
| US5061282A (en) * | 1989-10-10 | 1991-10-29 | Jacobs Jared J | Cochlear implant auditory prosthesis |
| US5005574A (en) * | 1989-11-28 | 1991-04-09 | Medical Engineering And Development Institute, Inc. | Temperature-based, rate-modulated cardiac therapy apparatus and method |
| US5320642A (en) * | 1990-06-01 | 1994-06-14 | Board Of Regents For The University Of Ok | Method for alleviating and diagnosing symptoms of heart block |
| US5083564A (en) * | 1990-06-01 | 1992-01-28 | Board Of Regents Of The University Of Oklahoma | Method for alleviating and diagnosing symptoms of heart block |
| US5502481A (en) * | 1992-11-16 | 1996-03-26 | Reveo, Inc. | Desktop-based projection display system for stereoscopic viewing of displayed imagery over a wide field of view |
| WO1993001862A1 (en) * | 1991-07-22 | 1993-02-04 | Cyberonics, Inc. | Treatment of respiratory disorders by nerve stimulation |
| CA2058179C (en) * | 1991-12-20 | 1999-02-09 | Roland Drolet | Basic electrophysiological conditioning system and method |
| US5551446A (en) * | 1992-12-30 | 1996-09-03 | Apollo Research Corp. | Reflex measuring device, and method |
| US5360438A (en) * | 1993-01-26 | 1994-11-01 | Fisher Mary R | Method and device for improving cranial nerve function to improve muscle function and thereby overcome visual/perceptual dysfunction |
| EP0617982A1 (en) * | 1993-03-11 | 1994-10-05 | Zentralinstitut Für Biomedizinische Technik Universität Ulm | Method and apparatus for neuromagnetical stimulation |
| US5713924A (en) * | 1995-06-27 | 1998-02-03 | Medtronic, Inc. | Defibrillation threshold reduction system |
| US5782873A (en) * | 1995-10-11 | 1998-07-21 | Trustees Of Boston University | Method and apparatus for improving the function of sensory cells |
-
1996
- 1996-08-27 US US08/703,674 patent/US5782873A/en not_active Expired - Lifetime
- 1996-09-30 WO PCT/US1996/015632 patent/WO1997013551A1/en active Application Filing
- 1996-09-30 AU AU73798/96A patent/AU7379896A/en not_active Abandoned
-
1997
- 1997-11-24 US US08/979,453 patent/US6032074A/en not_active Expired - Lifetime
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO1997013551B1 (en) | Method and apparatus for improving the function of sensory cells | |
| US6032074A (en) | Method and apparatus for improving the function of sensory cells | |
| US5964789A (en) | Transcutaneous electric muscle/nerve controller/feedback unit | |
| US7636603B1 (en) | Bionic ear implant | |
| US7349739B2 (en) | Method and apparatus for neurophysiologic performance | |
| US7894910B2 (en) | Systems and methods for implantable leadless cochlear stimulation | |
| US5913882A (en) | Neural stimulation techniques with feedback | |
| US4535777A (en) | Method of providing electrical stimulation of tissue | |
| US8346366B2 (en) | Spinal cord implant systems and methods | |
| US4805636A (en) | System for controlling muscle response | |
| US7117038B1 (en) | Method and system for obtaining stapedial reflexes in cochlear implant users using multiband stimuli | |
| US20070179565A1 (en) | System for generating a cochlear implant program using multi-electrode stimulation to elicit the electrically-evoked compound action potential | |
| DE69612020D1 (en) | DEVICE AND METHOD FOR THE AUTOMATIC DETERMINATION OF STIMULATION PARAMETERS | |
| US20080221640A1 (en) | Multi-electrode stimulation to elicit electrically-evoked compound action potential | |
| AU2016208972A1 (en) | Method and device for neural implant communication | |
| US20200376266A1 (en) | Non-Invasive Nerve Stimulation to Delay Urination | |
| Simmons et al. | A functioning multichannel auditory nerve stimulator a preliminary report on two human volunteers | |
| US20190151658A1 (en) | Electrical pulse stimulation system and controlling method thereof, and electrical pulse stimulation therapy | |
| Sun et al. | Corticofugal control of central auditory sensitivity in the big brown bat, Eptesicus fuscus | |
| US8233989B1 (en) | System and method for fitting a hearing prosthesis sound processor using alternative signals | |
| CN111918693A (en) | Non-invasive nerve stimulation | |
| US20200297992A1 (en) | Primary Dysmenorrhea Pain Reduction | |
| US20240100342A1 (en) | Feedback control of electrical stimulation therapy based on electric field imaging | |
| JPWO2022189862A5 (en) | ||
| Eldeeb et al. | COMPARISON BETWEEN BEHAVIOURAL-BASED MAPPING AND ESRT-BASED MAPPING IN COCHLEAR IMPLANTEES |