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WO1997004811A3 - Utilisation de preparations liposomales en lymphographie indirecte par imagerie par resonance magnetique - Google Patents

Utilisation de preparations liposomales en lymphographie indirecte par imagerie par resonance magnetique Download PDF

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Publication number
WO1997004811A3
WO1997004811A3 PCT/DE1996/001433 DE9601433W WO9704811A3 WO 1997004811 A3 WO1997004811 A3 WO 1997004811A3 DE 9601433 W DE9601433 W DE 9601433W WO 9704811 A3 WO9704811 A3 WO 9704811A3
Authority
WO
WIPO (PCT)
Prior art keywords
indirect
liposomal preparations
lymphography
mri
mri lymphography
Prior art date
Application number
PCT/DE1996/001433
Other languages
German (de)
English (en)
Other versions
WO1997004811A2 (fr
Inventor
Andreas Sachse
Johannes Platzek
Bernd Misselwitz
Andreas Muehler
Georg Roessling
Original Assignee
Schering Ag
Andreas Sachse
Johannes Platzek
Bernd Misselwitz
Andreas Muehler
Georg Roessling
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag, Andreas Sachse, Johannes Platzek, Bernd Misselwitz, Andreas Muehler, Georg Roessling filed Critical Schering Ag
Priority to AU68693/96A priority Critical patent/AU6869396A/en
Publication of WO1997004811A2 publication Critical patent/WO1997004811A2/fr
Publication of WO1997004811A3 publication Critical patent/WO1997004811A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1812—Suspensions, emulsions, colloids, dispersions liposomes, polymersomes, e.g. immunoliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne l'utilisation de liposomes chargés en agents de contraste pour la lymphographie interstitielle.
PCT/DE1996/001433 1995-08-01 1996-07-25 Utilisation de preparations liposomales en lymphographie indirecte par imagerie par resonance magnetique WO1997004811A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU68693/96A AU6869396A (en) 1995-08-01 1996-07-25 Use of liposomal preparations in indirect mri lymphography

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19529922.1 1995-08-01
DE1995129922 DE19529922A1 (de) 1995-08-01 1995-08-01 Verwendung von liposomalen Zubereitungen in der indirekten MRT-Lymphographie

Publications (2)

Publication Number Publication Date
WO1997004811A2 WO1997004811A2 (fr) 1997-02-13
WO1997004811A3 true WO1997004811A3 (fr) 1997-08-07

Family

ID=7769485

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1996/001433 WO1997004811A2 (fr) 1995-08-01 1996-07-25 Utilisation de preparations liposomales en lymphographie indirecte par imagerie par resonance magnetique

Country Status (3)

Country Link
AU (1) AU6869396A (fr)
DE (1) DE19529922A1 (fr)
WO (1) WO1997004811A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115364246B (zh) * 2021-05-18 2024-07-23 上海交通大学医学院附属第九人民医院 一种靶向造影剂及其制备方法和应用

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990004943A1 (fr) * 1988-11-09 1990-05-17 Unger Evan C Agents liposomiques de contraste radiologique
US5277914A (en) * 1989-03-31 1994-01-11 The Regents Of The University Of California Preparation of liposome and lipid complex compositions
WO1994008626A1 (fr) * 1992-10-16 1994-04-28 Andreas Sachse Procede et dispositif de preparation de systemes disperses liquides
DE4328331A1 (de) * 1993-08-18 1995-02-23 Andreas Dr Sachse Kontinuierliches Hochdruckextrusionsverfahren zur Herstellung von Liposomen und Emulsionen
DE4341472A1 (de) * 1993-12-02 1995-06-08 Schering Ag Verfahren zur Erhöhung der Stabilität von hydrophile Wirkstoffe enthaltenden Liposomensuspensionen
US5534241A (en) * 1993-07-23 1996-07-09 Torchilin; Vladimir P. Amphipathic polychelating compounds and methods of use
WO1996024381A2 (fr) * 1995-02-09 1996-08-15 Schering Aktiengesellschaft Liposomes contenant des agents de contraste pour l'imagerie relative au pool sanguin intracardiaque

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5114703A (en) * 1989-05-30 1992-05-19 Alliance Pharmaceutical Corp. Percutaneous lymphography using particulate fluorocarbon emulsions

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990004943A1 (fr) * 1988-11-09 1990-05-17 Unger Evan C Agents liposomiques de contraste radiologique
US5277914A (en) * 1989-03-31 1994-01-11 The Regents Of The University Of California Preparation of liposome and lipid complex compositions
WO1994008626A1 (fr) * 1992-10-16 1994-04-28 Andreas Sachse Procede et dispositif de preparation de systemes disperses liquides
US5534241A (en) * 1993-07-23 1996-07-09 Torchilin; Vladimir P. Amphipathic polychelating compounds and methods of use
DE4328331A1 (de) * 1993-08-18 1995-02-23 Andreas Dr Sachse Kontinuierliches Hochdruckextrusionsverfahren zur Herstellung von Liposomen und Emulsionen
DE4341472A1 (de) * 1993-12-02 1995-06-08 Schering Ag Verfahren zur Erhöhung der Stabilität von hydrophile Wirkstoffe enthaltenden Liposomensuspensionen
WO1996024381A2 (fr) * 1995-02-09 1996-08-15 Schering Aktiengesellschaft Liposomes contenant des agents de contraste pour l'imagerie relative au pool sanguin intracardiaque

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CAPELLIER M ET AL: "RADIOPAQUE LIPOSOMES FOR COMPUTED TOMOGRAPHY OPACIFICATION", CARDIOLOGY AND IMAGING, NEW ORLEANS, NOV. 4 - 7, 1988, vol. 10 PART 1/04, 4 November 1988 (1988-11-04), HARRIS G;WALKER C, pages 491/492, XP000093331 *
CARIDE V J: "TECHNICAL AND BIOLOGICAL CONSIDERATIONS ON THE USE OF RADIOLABELED LIPOSOMES FOR DIAGNOSTIC IMAGING", INTERNATIONAL JOURNAL OF RADIATION APPLICATIONS AND INSTRUMENTATION PART B: NUCLEAR MEDICINE AND BIOLOGY, vol. 17, no. 1, 1 January 1990 (1990-01-01), pages 35 - 39, XP000100539 *
SCHNEIDER, T. ET AL: "Generation of contrast-carrying liposomes of defined size with a new continuous high pressure extrusion method", INT. J. PHARM., VOL. 117, NO. 1, PAGE(S) 1-12, 1995, XP000674324 *
TILCOCK C ET AL: "LIPOSOMAL GD-DTPA: PREPARATION AND CHARACTERIZATION OF RELAXIVITY", RADIOLOGY, vol. 171, no. 1, 1 April 1989 (1989-04-01), pages 77 - 80, XP000386331 *
TRUBETSKOY V S ET AL: "NEW APPROACHES IN THE CHEMICAL DESIGN OG GD-CONTAINING LIPOSOMES FOR USE IN MAGNETIC RESONANCE IMAGING OF LYMPH NODES", JOURNAL OF LIPOSOME RESEARCH, vol. 4, no. 2, 1994, pages 961 - 980, XP000619021 *

Also Published As

Publication number Publication date
DE19529922A1 (de) 1997-02-06
WO1997004811A2 (fr) 1997-02-13
AU6869396A (en) 1997-02-26

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