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WO1997049653A3 - Banque de tyrphostine en phase solide liee a des matrices a memoires - Google Patents

Banque de tyrphostine en phase solide liee a des matrices a memoires Download PDF

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Publication number
WO1997049653A3
WO1997049653A3 PCT/US1997/011035 US9711035W WO9749653A3 WO 1997049653 A3 WO1997049653 A3 WO 1997049653A3 US 9711035 W US9711035 W US 9711035W WO 9749653 A3 WO9749653 A3 WO 9749653A3
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WO
WIPO (PCT)
Prior art keywords
memories
tyrphostin
matrix materials
matrices
compounds
Prior art date
Application number
PCT/US1997/011035
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English (en)
Other versions
WO1997049653A2 (fr
WO1997049653A9 (fr
Inventor
Xiao-Yi Xiao
Shuhao Shi
Zahra Parandoosh
Michael P Nova
Original Assignee
Irori
Xiao Xiao Yi
Shuhao Shi
Zahra Parandoosh
Michael P Nova
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/711,426 external-priority patent/US6284459B1/en
Priority claimed from US08/709,435 external-priority patent/US6017496A/en
Priority claimed from US08/723,423 external-priority patent/US5961923A/en
Application filed by Irori, Xiao Xiao Yi, Shuhao Shi, Zahra Parandoosh, Michael P Nova filed Critical Irori
Priority to AU35779/97A priority Critical patent/AU3577997A/en
Publication of WO1997049653A2 publication Critical patent/WO1997049653A2/fr
Publication of WO1997049653A3 publication Critical patent/WO1997049653A3/fr
Publication of WO1997049653A9 publication Critical patent/WO1997049653A9/fr

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
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    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
    • G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

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Abstract

L'invention concerne des combinaisons (ou matrices à mémoires) d'éléments matriciels à mémoires qui constituent des supports d'enregistrement à adressage ou programmation à distance ou qui sont associés avec des symboles imprimés. On décrit des combinaisons d'éléments matriciels, de mémoires et de molécules liées représentant des analogues de la tyrphostine. Les éléments matriciels sont du type de ceux utilisés comme support de synthèse chimique et biochimique en phase solide, dosages immunologiques et réaction d'hybridation. Ils peuvent inclure des fluorophores ou autres fractions luminescentes donnant des matrices luminescentes à mémoires. Les mémoires sont à supports d'informations électroniques et optiques, et aussi à supports optiques du type code à barres et code utilisable par l'ordinateur. Le système d'association permet de marquer des molécules et des particules biologiques, comme les composés de tyrphostine, au voisinage ou au contact physique de la combinaison matricielle en établissant une programmation de mémoire avec des caractéristiques d'identification susceptibles d'être extraites ultérieurement comme repères d'identification. On décrit les composés de tyrphostine et leurs procédés de préparation.
PCT/US1997/011035 1996-06-24 1997-06-24 Banque de tyrphostine en phase solide liee a des matrices a memoires WO1997049653A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU35779/97A AU3577997A (en) 1996-06-24 1997-06-24 Solid phase tyrphostin library linked to matrices with memories

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US2070696P 1996-06-24 1996-06-24
US60/020,706 1996-06-24
US08/711,426 US6284459B1 (en) 1995-04-25 1996-09-05 Solid support matrices with memories and combinatorial libraries therefrom
US08/711,426 1996-09-05
US08/709,435 1996-09-06
US08/709,435 US6017496A (en) 1995-06-07 1996-09-06 Matrices with memories and uses thereof
US08/723,423 1996-09-30
US08/723,423 US5961923A (en) 1995-04-25 1996-09-30 Matrices with memories and uses thereof

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WO1997049653A3 true WO1997049653A3 (fr) 1998-02-26
WO1997049653A9 WO1997049653A9 (fr) 1998-04-16

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DE19823660C1 (de) * 1998-05-20 1999-10-07 Nanomont Ges Fuer Nanotechnolo Verfahren und Vorrichtung zur Fixierung fester Mikro- und/oder Nanoobjekte
US6998249B1 (en) * 1999-09-27 2006-02-14 Pharmacia & Upjohn Company Toxicity screening method
KR100917731B1 (ko) 2001-05-11 2009-09-15 파나소닉 주식회사 생체분자 기판 및 그것을 이용한 검사 및 진단의 방법 및장치
ATE535612T1 (de) 2006-03-06 2011-12-15 Ceetox Inc Toxizitätsscreeningverfahren
WO2016122567A1 (fr) * 2015-01-30 2016-08-04 Hewlett-Packard Development Company, L.P. Codage cyclique m-aire

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