+

WO1996038122A1 - Composition dentifrice sous forme de comprime - Google Patents

Composition dentifrice sous forme de comprime Download PDF

Info

Publication number
WO1996038122A1
WO1996038122A1 PCT/ES1996/000123 ES9600123W WO9638122A1 WO 1996038122 A1 WO1996038122 A1 WO 1996038122A1 ES 9600123 W ES9600123 W ES 9600123W WO 9638122 A1 WO9638122 A1 WO 9638122A1
Authority
WO
WIPO (PCT)
Prior art keywords
composition according
dentifrice composition
tablet
dentifrice
present
Prior art date
Application number
PCT/ES1996/000123
Other languages
English (en)
Spanish (es)
Inventor
Vicente Galiana Arano
Original Assignee
Compañia Anonima De Importaciones Y Elaboraciones, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Compañia Anonima De Importaciones Y Elaboraciones, S.A. filed Critical Compañia Anonima De Importaciones Y Elaboraciones, S.A.
Publication of WO1996038122A1 publication Critical patent/WO1996038122A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A61K8/022—Powders; Compacted Powders
    • A61K8/0225—Granulated powders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants

Definitions

  • the present invention relates to a dentifrice composition presented in the form of a tablet specially designed for use in oral hygiene without using a toothbrush.
  • This patent refers to a toothpaste presented in powder or tablet form which has been obtained by direct compression.
  • the tablets obtained by direct compression that is without prior granulation provide little homogeneity in the weight of the batches obtained.
  • they have little consistency so that when they break in the mouth they disintegrate into particles with a size similar to that of the powder, which inhibits the salivation action of the mouth. Consequently, a brush and water should be used to achieve proper cleaning of the teeth.
  • said direct compression of the powder Toothpaste entails inconveniences in terms of obtaining pills in perfect condition, that is, without exfoliation or "caping" during compression, and obtaining pills with a final non-homogeneous weight in each of the lots obtained by said procedure .
  • the tablet-shaped composition of the present invention does not require rinsing. final, although this is preferable.
  • the dentifrice composition in tablet form, object of the present invention comprises: an abrasive agent between 15 and 70%, a foaming agent between 0.2 and 4.1%, solid sugars between 41 and 80%, and lubricants between 0 , 6 and 6%.
  • an abrasive agent is understood as a phosphate or an alkaline earth carbonate, the alkaline earth phosphate being anhydrous dicalcium phosphate, dihydrated phosphate, sodium polyphosphates or mixtures of the foregoing and 30% by weight being present in a preferred embodiment of the invention.
  • the large amount of sugars used allows activating the salivation of the mouth thereby favoring the dissolution of the tablet or of the portions or granules obtained when said tablet is broken in the mouth.
  • the water cleaning effect is obtained by activating saliva and the effect Mechanical brush is achieved by measuring the portions or granules obtained when the tablet is broken.
  • the present dentifrice composition presented in the form of a tablet, thus allows oral hygiene to be performed without the toothbrush and toothpaste or toothpaste currently used, as well as water.
  • obtaining a toothpaste in the form of a tablet entails a series of technical and utilization advantages that will be described below.
  • the use of a tablet to perform oral hygiene is much more comfortable and in turn requires fewer conditions inherent in its purpose.
  • Presenting a toothpaste in tablet form provides easy handling.
  • the tablet is a compact unit and not broken down as is the case with tooth dust.
  • the same amount of toothpaste occupies less space in tablet than in powder.
  • the composition of the invention does not contain water, nor does it easily absorb ambient humidity, whereby the germicidal action is optimal. In the case, unlikely, that moisture absorbed its content in adjuvants (parahydroxybenzoates, sorbic acid, etc.) guarantees its stability.
  • germicidal agents in the presence of water can be presented in an ionic form, and it is known that any germicide in an ionic form decreases its effectiveness, even substantially inhibiting it over time.
  • the dentifrice composition of the invention comprises germicidal agents such as triclosan, bromochlorophenol or chlorhexidine, components, which even at very low concentrations inhibit the proliferation of the microorganisms that form the plaque bacterial, in addition to providing long-acting antiseptic action.
  • germicidal agents such as triclosan, bromochlorophenol or chlorhexidine
  • the dentifrice composition according to the present invention further comprises fluorine salts to protect dental plaque between 0.05 and 0.2%, preferably 0.15%, such as sodium fluoride and sodium monofluor phosphate; aromas between 1 and 2%, preferably fruity and menthol aromas present in 1% to give a pleasant smell; sweeteners between 0.001 and 0.15%, preferably saccharin present in 0.1% to flavor the tablet and preservatives between 0.02 and 1.5%, preferably 0.3%, such as for example sorbic acid and parahydroxybenzoates.
  • fluorine salts to protect dental plaque between 0.05 and 0.2%, preferably 0.15%, such as sodium fluoride and sodium monofluor phosphate
  • aromas between 1 and 2%, preferably fruity and menthol aromas present in 1% to give a pleasant smell
  • sweeteners between 0.001 and 0.15%, preferably saccharin present in 0.1% to flavor the tablet and preservatives between 0.02 and 1.5%, preferably 0.3%, such as for example sorb
  • hypoglycemic sugars is substantially higher than the dentifrices known so far. This substantially higher amount has the function of activating the salivation of the mouth and thus facilitating the dissolution of the tablet in the same.
  • saliva is an antiseptic that increases the effectiveness of any active substance soluble in it. Being antiseptic, saliva acts as a natural defense of the oral cavity.
  • a dentifrice tablet which has the advantage that when the mouth is broken by the action of the teeth, the salivation action is not inhibited.
  • the abrasive efficiency of the tablet is greater than that of the powder, without ever damaging the tooth enamel or gums, so it can be used with a good result without the need of the brush. This is due, on the one hand, to the increase of the grain size since the granulometry of the dental powder is between 2 and 20 ⁇ , while the size of the portions of the tablet are much larger and therefore provide a greater abrasive effect.
  • the hardness that dicalcium phosphate provides for being anhydrous, that is, free of water. On the contrary, in the presence of water the hardness is inferior since the most stable structure is the hydrated one and this one contributes lower hardness values.
  • the following steps are carried out: the components of the composition are mixed by the dilution method; a first compaction is performed; the tablet obtained is granulated dry; and finally a second compaction is carried out which allows obtaining the tablet of the invention.
  • the components of the composition are mixed using the same method of dilutions; the powder moistened with a binder solution is wet granulated in a granulator or the like; It is dried in a static or fluid bed stove, and finally, it is compacted.
  • the tablet obtained according to said procedure small portions, granules, with a size larger than those of the dental powder are obtained because, on the one hand, the tablet of the present invention does not contain disintegrants and, on the other, due to the double compression performed in the procedure for obtaining it.
  • Such granules take longer to melt in the mouth, thereby achieving that the disinfectant and abrasive action is prolonged for longer.
  • the prior wet or dry granulation technique allows batches of tablets with a homogeneous final weight and with the desired hardness to be obtained.
  • a preferred embodiment of the invention consists in presenting the colored or colorless tablets.
  • Edible tablet The sugars used in the tablet are sugars that have no negative effect on diabetics.
  • This example was based on the procedure widely known as dry granulation prior granulation.
  • Triclosan (IRGASAN D.P. 300) 0, 20 Aroma mint piperine menthol 1, 00 Aroma winter grenn oil Aroma eugenol Aroma strawberry
  • C.S. means sufficient quantity for 100% Once all components were mixed by the dilution method, a first compaction was performed.
  • This example was based on the procedure widely known as wet granulation prior granulation.
  • Dicalcium phosphate dihydrate 20.00 Anhydrous dicalcium phosphate Calcium carbonate 20, 00 Monofluor sodium phosphate 0,, 78 15 Triclosan (IRGASAN DP 300) 0,, 20 Aroma mint piperine menthol Aroma winter grenn oil o,, 30 Aroma eugenol o,, 10 Strawberry flavor 20 Talc 1,. 00
  • Triclosan (IRGASA D.P. 300) 0.20

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)

Abstract

La composition dentifrice comprend entre 15 et 70 % d'un agent abrasif, entre 0,2 et 4,1 % d'un agent moussant, entre 41 et 80 % de sucres solides, et entre 0,6 et 6 % de lubrifiants, et en outre elle comprend entre 0,05 et 0,2 %, de préférence 0,15 %, de sels de fluor, entre 1 et 2 %, de préférence 1 %, d'arômes, entre 0,01 et 0,15 %, de préférence 0,1 %, d'édulcorants, entre 0,02 et 1,5 %, de préférence, 3 % d'agents conservateurs. Elle permet de réaliser l'hygiène buccale en se passant de la brosse à dents et de la pâte dentifrice ou de la poudre dentaire, ainsi que de l'eau. L'effet nettoyant de l'eau est obtenu par l'activation de la salive et l'effet mécanique de la brosse à dents est obtenu par la taille des morceaux ou des granules obtenus lorsque le comprimé se casse. Il ne contient pas d'eau, et n'absorbe pas facilement l'humidité ambiante, et par conséquent son action germicide est optimale. Il est facile à utiliser.
PCT/ES1996/000123 1995-06-01 1996-05-30 Composition dentifrice sous forme de comprime WO1996038122A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES9501093A ES2092967B1 (es) 1995-06-01 1995-06-01 Composicion dentifrica en forma de comprimido.
ESP9501093 1995-06-01

Publications (1)

Publication Number Publication Date
WO1996038122A1 true WO1996038122A1 (fr) 1996-12-05

Family

ID=8290597

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ES1996/000123 WO1996038122A1 (fr) 1995-06-01 1996-05-30 Composition dentifrice sous forme de comprime

Country Status (2)

Country Link
ES (1) ES2092967B1 (fr)
WO (1) WO1996038122A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3106059A1 (fr) 2020-01-14 2021-07-16 Jean Dominque DANA Composition dentifrice comestible à sucer ou à macher, procédé de préparation de ladite composition dentifrice

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3151028A (en) * 1958-10-31 1964-09-29 Lever Brothers Ltd Dental tablet
US4411885A (en) * 1980-09-30 1983-10-25 Barels Ronald R Vitamin E oil based dentifrice
GB2163348A (en) * 1984-08-21 1986-02-26 Dentab U K Limited Tooth cleaning tablet
WO1988010110A1 (fr) * 1987-06-25 1988-12-29 Dentab, Inc. Tablette de fluoruration et de nettoyage des dents
US4978521A (en) * 1990-01-03 1990-12-18 John Duncan Blue Color coded flavored dentifrice toothpowders
ES2023295A6 (es) * 1989-08-25 1992-01-01 Colgate Palmolive Co Composicion oral antibacteriana, anti-placa y anti-calculos.

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3151028A (en) * 1958-10-31 1964-09-29 Lever Brothers Ltd Dental tablet
US4411885A (en) * 1980-09-30 1983-10-25 Barels Ronald R Vitamin E oil based dentifrice
GB2163348A (en) * 1984-08-21 1986-02-26 Dentab U K Limited Tooth cleaning tablet
WO1988010110A1 (fr) * 1987-06-25 1988-12-29 Dentab, Inc. Tablette de fluoruration et de nettoyage des dents
ES2023295A6 (es) * 1989-08-25 1992-01-01 Colgate Palmolive Co Composicion oral antibacteriana, anti-placa y anti-calculos.
US4978521A (en) * 1990-01-03 1990-12-18 John Duncan Blue Color coded flavored dentifrice toothpowders

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3106059A1 (fr) 2020-01-14 2021-07-16 Jean Dominque DANA Composition dentifrice comestible à sucer ou à macher, procédé de préparation de ladite composition dentifrice
WO2021144211A1 (fr) 2020-01-14 2021-07-22 Jean Dominique Dana Composition dentifrice comestible à sucer ou à macher, procédé de préparation de ladite composition dentifrice

Also Published As

Publication number Publication date
ES2092967A1 (es) 1996-12-01
ES2092967B1 (es) 1997-08-01

Similar Documents

Publication Publication Date Title
US6054119A (en) Preparation used in dental care
US6436370B1 (en) Dental anti-hypersensitivity composition and method
US10058497B2 (en) Oral hygiene products and method of using the same
ES2385236B2 (es) Composición y método para reducir la desmineralización de los dientes.
US8192724B2 (en) Oral care tablet
EP0273962A1 (fr) Compositions pour l'action prolongee d'agents antiplaque
US10517808B2 (en) Oral care formulation and method for the removal of tartar and plaque from teeth
US6696043B2 (en) Teeth whitening composition in the form of a chewing gum
EP1928429A2 (fr) Compositions effervescentes de soins buccaux et leurs methodes d'utilisation
US11723847B2 (en) Dual component oral composition for enhancing remineralization of teeth
WO1996038122A1 (fr) Composition dentifrice sous forme de comprime
JPS603285B2 (ja) 口腔用組成物
ES2566615T3 (es) Composiciones anticaries que contienen faseolamina
CN114129456A (zh) 速溶漱口水粉
JP2005289848A (ja) 歯磨剤
JP2018123107A (ja) 口腔ケア用固形組成物
KR20020086064A (ko) 숯가루를 함유하는, 니코틴 제거용 치약 조성물

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): BR CA JP MX US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: CA

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载