WO1996025194A1 - Medication and apparatus and method of applying medication - Google Patents
Medication and apparatus and method of applying medication Download PDFInfo
- Publication number
- WO1996025194A1 WO1996025194A1 PCT/GB1996/000292 GB9600292W WO9625194A1 WO 1996025194 A1 WO1996025194 A1 WO 1996025194A1 GB 9600292 W GB9600292 W GB 9600292W WO 9625194 A1 WO9625194 A1 WO 9625194A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- medication
- mousse
- foam
- injuries
- dispenser
- Prior art date
Links
- 239000003814 drug Substances 0.000 title claims abstract description 45
- 229940079593 drug Drugs 0.000 title claims abstract description 38
- 238000000034 method Methods 0.000 title description 4
- 208000027418 Wounds and injury Diseases 0.000 claims abstract description 26
- 230000006378 damage Effects 0.000 claims abstract description 23
- 208000014674 injury Diseases 0.000 claims abstract description 23
- 241000195940 Bryophyta Species 0.000 claims abstract description 18
- 235000011929 mousse Nutrition 0.000 claims abstract description 18
- 239000006260 foam Substances 0.000 claims abstract description 16
- 239000004088 foaming agent Substances 0.000 claims abstract description 7
- 239000003380 propellant Substances 0.000 claims abstract description 7
- 239000007788 liquid Substances 0.000 claims abstract description 6
- 239000002674 ointment Substances 0.000 claims description 8
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 6
- 239000003921 oil Substances 0.000 claims description 6
- 210000002268 wool Anatomy 0.000 claims description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 5
- 235000019271 petrolatum Nutrition 0.000 claims description 4
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims description 3
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 3
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical class CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 claims description 3
- 244000223014 Syzygium aromaticum Species 0.000 claims description 3
- 235000016639 Syzygium aromaticum Nutrition 0.000 claims description 3
- 229960000583 acetic acid Drugs 0.000 claims description 3
- 239000010642 eucalyptus oil Substances 0.000 claims description 3
- 229940044949 eucalyptus oil Drugs 0.000 claims description 3
- 239000012362 glacial acetic acid Substances 0.000 claims description 3
- 229940041616 menthol Drugs 0.000 claims description 3
- 239000011928 denatured alcohol Substances 0.000 claims description 2
- TVFOIIKKYVPRTQ-UHFFFAOYSA-N COC(C1=C(C=CC=C1)O)=O.C1(=CC=CC=C1)O Chemical compound COC(C1=C(C=CC=C1)O)=O.C1(=CC=CC=C1)O TVFOIIKKYVPRTQ-UHFFFAOYSA-N 0.000 claims 1
- MDOXVLYRJCOYGL-UHFFFAOYSA-N benzene-1,3-diol;2-hydroxybenzoic acid Chemical compound OC1=CC=CC(O)=C1.OC(=O)C1=CC=CC=C1O MDOXVLYRJCOYGL-UHFFFAOYSA-N 0.000 claims 1
- 239000010632 citronella oil Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 description 11
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 description 4
- GHMLBKRAJCXXBS-UHFFFAOYSA-N resorcinol Chemical compound OC1=CC=CC(O)=C1 GHMLBKRAJCXXBS-UHFFFAOYSA-N 0.000 description 4
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 4
- 150000001298 alcohols Chemical class 0.000 description 3
- 238000002483 medication Methods 0.000 description 3
- 239000011505 plaster Substances 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 244000166675 Cymbopogon nardus Species 0.000 description 2
- 235000018791 Cymbopogon nardus Nutrition 0.000 description 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 2
- 238000005299 abrasion Methods 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 229960001047 methyl salicylate Drugs 0.000 description 2
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 2
- 229960004889 salicylic acid Drugs 0.000 description 2
- 206010012444 Dermatitis diaper Diseases 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- 206010053615 Thermal burn Diseases 0.000 description 1
- 206010046996 Varicose vein Diseases 0.000 description 1
- 230000003444 anaesthetic effect Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000000266 injurious effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- MYWUZJCMWCOHBA-VIFPVBQESA-N methamphetamine Chemical compound CN[C@@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-VIFPVBQESA-N 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 208000027185 varicose disease Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/122—Foams; Dry foams
Definitions
- THIS INVENTION relates to medication for application to external injuries such as burns, scalds, cuts or abrasions or for application to legs affected by varicose veins, etc.
- the invention also relates to apparatus for and a method of applying medication to external injuries.
- apparatus for applying medication to an external injury comprising a dispenser adapted to dispense medication, in the form of a mousse or foam, directly onto such injuries.
- a medication for application to external injuries comprising any of the following alone or in combination:
- the medication additionally comprises a wool alcohol ointment and/or white soft paraphine (petroleum jelly) .
- a wool alcohol ointment and/or white soft paraphine petroleum jelly
- a medication according to the second aspect of the invention is incorporated in a dispenser according to the first aspect of the invention for dispensing thereby in the form of a mousse or foam.
- a dressing for external injuries including a moisture permeable pad impregnated with a medicament according to the second aspect of the invention.
- a dispensing apparatus in the form of a pressurised container with a manually operable dispensing valve, known per se , the container containing a quantity of a liquid medicament under pressure of a propellant and incorporating a foaming agent whereby when the valve is operated manually, the liquid is dispensed from the dispenser in the form of a foam or mousse.
- the dispenser preferably has a suitable nozzle to facilitate application of the foam or mousse to a desired wound location.
- the dispenser may be supplied with a plurality of interchangeable nozzles appropriate to different injuries or treatment situations.
- one such nozzle may have a wide flat outlet for dispensing a wide ribbon of the foam or mousse
- another nozzle may have an outlet in the form of a narrow bore for dispensing a fine strand of the foam or mousse
- another nozzle may have an outlet in the form of a wider bore for dispensing a more substantial body of foam or mousse
- a preferred medication comprises a mixture, with wool alcohols ointment and white soft paraphine, of a mixture of oils and other ingredients, referred to below, for convenience, as "Mixture A" and constituted as follows:-
- Mixture A set out above is a concentrate and is not intended to be applied to the body in that concentrated form but only in dilution with a matrix material such as the wool alcohols ointment and white soft paraphine mixture referred to.
- the medication described above is incorporated in a pressurised foam dispenser
- the medication may also be supplied in jars in the conventional way.
- the medication may be used to impregnate a moisture- permeable pad of a sticking plaster or other dressing, the sticking plaster or dressing, with the medication- impregnated pad being stored, in sterile condition, in a sealed package until required.
- forms of medication other than that recited above may, in accordance with the invention, be dispensed in the form of a mousse or foam, including medications which are not strictly speaking liquid at the temperature, but for example in the form of a gel, such as petroleum jelly and medicaments having a petroleum jelly base.
- the material dispensed in the form of a foam or mousse may be such that, after application, it will cure to form a flexible protective foam covering over the site of the injury, thereby serving as a substitute for a sticking plaster or dressing.
- different medications may be supplied in similar dispensers embodying the invention, and the medications may be coloured to indicate the kind of medication used.
- a setting medication may be of one colour; a medication specifically intended for burns may be of a different colour, and so on.
- the container is pressurised by an appropriate propellant and foaming agent selected so as to be non-injurious to the patient and so as to be compatible with the medication.
- the propellant or foaming agent may be, or include, a component having healing properties, for example, oxygen or carbon dioxide, for example, depending upon the treatment requirements.
- the medication may also, if desired, incorporate a local anaesthetic.
- the propellant may also act as the foaming agent.
- the propellant and foaming agent may be distinct from one another.
- the medication may incorporate a bleeding retarder or styptic.
- a suitable medication in the form of a mousse to external injuries has various advantages. For example, it can be applied without contact of anything but the mousse with the injury and serves to cover the injury rapidly and thereby exclude germs etc.
- Such a procedure has particular advantages, for example, in treating minor cuts and abrasions in small children or rashes such as "nappy rash", since the injury need not be touched and there is less chance of hurting the child.
- the concealment of the injury by the mousse tends to minimise the child's alarm at the sight of the injury and provides reassurance.
- a mousse also has advantages in more serious situations, as, for example, where injured persons are trapped so that an injury is not readily accessible for the application of normal wound dressings etc.
- the dispenser may be fitted with a substantially elongate nozzle or nozzle extension which can readily be extended through relatively small openings to allow medication to be applied to injuries which can be seen but not readily reached by more conventional means, so that such medication can be applied, as a first-aid measure, even before trapped injured persons can be freed.
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Abstract
Apparatus for applying medication to an external injury comprises a pressurised container of a liquid medicament under pressure of a propellant and incorporating a foaming agent. Upon depression of a manually operable valve fitted with a nozzle, the medicament is discharged from the nozzle in the form of a foam or mousse, directly onto the injury.
Description
Title: "Medication and apparatus and method of applying medication"
THIS INVENTION relates to medication for application to external injuries such as burns, scalds, cuts or abrasions or for application to legs affected by varicose veins, etc. The invention also relates to apparatus for and a method of applying medication to external injuries.
According to a first aspect of the invention there is provided apparatus for applying medication to an external injury comprising a dispenser adapted to dispense medication, in the form of a mousse or foam, directly onto such injuries.
According to a second aspect of the invention there is provided a medication for application to external injuries, the medication comprising any of the following alone or in combination:
Eucalyptus oil
Menthol
Salicylic acid
Resorcinol
Chlorobutol
Methyl salicylate
Phenol
Oil citronella
Oil cloves
Industrial methylated spirit
Glacial acetic acid
Lignocaine alkaloid
Preferably the medication additionally comprises a wool alcohol ointment and/or white soft paraphine (petroleum jelly) .
In a preferred embodiment of the invention, a medication according to the second aspect of the invention is incorporated in a dispenser according to the first aspect of the invention for dispensing thereby in the form of a mousse or foam.
According to a further aspect of the invention there is provided a dressing for external injuries including a moisture permeable pad impregnated with a medicament according to the second aspect of the invention.
In a preferred embodiment of the invention, a dispensing apparatus is provided in the form of a pressurised container with a manually operable dispensing valve, known per se , the container containing a quantity of a liquid medicament under pressure of a propellant and incorporating a foaming agent whereby when the valve is operated manually, the liquid is dispensed from the dispenser in the form of a foam or mousse.
The dispenser preferably has a suitable nozzle to facilitate application of the foam or mousse to a desired wound location. Indeed, the dispenser may be supplied with a plurality of interchangeable nozzles appropriate to different injuries or treatment situations. For example, one such nozzle may have a wide flat outlet for dispensing a wide ribbon of the foam or mousse, another nozzle may have an outlet in the form of a narrow bore for dispensing a fine strand of the foam or mousse, another nozzle may have an outlet in the form of a wider bore for dispensing a more substantial body of foam or mousse, and so on.
A preferred medication comprises a mixture, with wool alcohols ointment and white soft paraphine, of a mixture of oils and other ingredients, referred to below, for convenience, as "Mixture A" and constituted as follows:-
Mixture A
Eucalyptus oil 260 ml
Menthol 66 g
Salicylic acid 20 g
Resorcinol 56 g
Chlorobutol 240 g
Methyl salicylate (not Lin. Meth. Sal) 128 ml
Phenol crystals 160 g
Oil citronella 200 ml
Oil cloves 160 g
Industrial eths 472 ml
Glacial acetic acid 48 ml
Lignocaine alkaloid 400 g
The above quantities produce 2 litres of mixture A. Mixture A above was used in preparation of an ointment having the composition set out below:-
Mixture A 125 ml
Wool Alcohols Ointment 1 kg W.S.P. 4 kg
In preparation of the ointment, the 125 ml of Mixture A was mixed with about 300 grams of wool alcohol ointment (warmed if necessary) and shaken until the components "gelled" together. The remainder of the above- noted ingredients was added and the whole mixed thoroughly.
It will be appreciated that Mixture A set out above is a concentrate and is not intended to be applied to the body in that concentrated form but only in dilution with a matrix material such as the wool alcohols ointment and white soft paraphine mixture referred to.
Whilst, in the preferred embodiment of the invention, the medication described above is incorporated in a pressurised foam dispenser, the medication may also be supplied in jars in the conventional way. Alternatively, the medication may be used to impregnate a moisture- permeable pad of a sticking plaster or other dressing, the sticking plaster or dressing, with the medication- impregnated pad being stored, in sterile condition, in a sealed package until required.
It will be appreciated that forms of medication other than that recited above may, in accordance with the invention, be dispensed in the form of a mousse or foam, including medications which are not strictly speaking liquid at the temperature, but for example in the form of a gel, such as petroleum jelly and medicaments having a petroleum jelly base.
It is also possible for the material dispensed in the form of a foam or mousse to be such that, after application, it will cure to form a flexible protective foam covering over the site of the injury, thereby serving as a substitute for a sticking plaster or dressing. If desired, different medications may be supplied in similar dispensers embodying the invention, and the medications may be coloured to indicate the kind of medication used. For example, a setting medication may be of one colour; a medication specifically intended for burns may be of a different colour, and so on.
When the medication is supplied in a mousse- dispensing container, the container is pressurised by an appropriate propellant and foaming agent selected so as to be non-injurious to the patient and so as to be compatible with the medication. In appropriate cases, the propellant or foaming agent may be, or include, a component having healing properties, for example, oxygen or carbon dioxide, for example, depending upon the treatment requirements. The medication may also, if desired, incorporate a local anaesthetic. It will be appreciated that the propellant may also act as the foaming agent. However, the propellant and foaming agent may be distinct from one another.
The medication may incorporate a bleeding retarder or styptic.
Application of a suitable medication in the form of a mousse to external injuries has various advantages. For example, it can be applied without contact of anything but the mousse with the injury and serves to cover the injury rapidly and thereby exclude germs etc. Such a procedure has particular advantages, for example, in treating minor cuts and abrasions in small children or rashes such as "nappy rash", since the injury need not be touched and there is less chance of hurting the child. Furthermore the concealment of the injury by the mousse tends to minimise the child's alarm at the sight of the injury and provides reassurance.
Application in the form of a mousse also has advantages in more serious situations, as, for example, where injured persons are trapped so that an injury is not readily accessible for the application of normal wound dressings etc. For such situations the dispenser may be fitted with a substantially elongate nozzle or nozzle
extension which can readily be extended through relatively small openings to allow medication to be applied to injuries which can be seen but not readily reached by more conventional means, so that such medication can be applied, as a first-aid measure, even before trapped injured persons can be freed.
Claims
1. Apparatus for applying medication to an external injury comprising a dispenser adapted to dispense medication, in the form of a mousse or foam, directly onto such injuries.
2. A medication for application to external injuries, the medication comprising any of the following alone or in combination:
Eucalyptus oil
Menthol
Salicylic acid
Resorcinol
Chlorobutol
Methyl salicylate
Phenol
Oil citronella
Oil cloves
Industrial methylated spirit
Glacial acetic acid
Lignocaine alkaloid
3. The medication of claim 2 additionally comprising a wool alcohol ointment and/or white soft paraphine (petroleum jelly) .
4. Apparatus according to claim 1 including a medication according to claim 2 or claim 3 within said dispenser for dispensing said medication in the form of a mousse of foam.
5. A dressing for external injuries including a moisture permeable pad impregnated with a medicament according to claim 2 or claim 3.
6. Apparatus according to claim 1 or claim 4 comprising a pressurised container with a manually operable dispensing valve, the container containing a quantity of a liquid medicament under pressure of a propellant and incorporating a foaming agent whereby when the valve is operated manually the liquid is dispensed from the dispenser in the form of a foam or mousse.
7. Apparatus according to claim 6 including a nozzle for application of the foam or mousse to a desired wound location.
8. Apparatus according to claim 7, including a plurality of interchangeable nozzles appropriate to different injuries or treatment situations.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9503119.1 | 1995-02-17 | ||
| GBGB9503119.1A GB9503119D0 (en) | 1995-02-17 | 1995-02-17 | Medication and apparatus and method of applying medication |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO1996025194A1 true WO1996025194A1 (en) | 1996-08-22 |
Family
ID=10769765
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/GB1996/000292 WO1996025194A1 (en) | 1995-02-17 | 1996-02-12 | Medication and apparatus and method of applying medication |
Country Status (2)
| Country | Link |
|---|---|
| GB (1) | GB9503119D0 (en) |
| WO (1) | WO1996025194A1 (en) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2353214A (en) * | 1999-07-06 | 2001-02-21 | Cooper John Philip | Topical Composition |
| WO2002062420A1 (en) * | 2001-01-22 | 2002-08-15 | SØRENSEN, Svein | Photodynamic stimulation device and methods |
| USRE38919E1 (en) | 1993-06-23 | 2005-12-13 | Btg International Limited | Injectable microfoam containing a sclerosing agent |
| US7025290B2 (en) | 1999-05-26 | 2006-04-11 | Btg International Limited | Generation of therapeutic microfoam |
| US7731986B2 (en) | 2003-11-17 | 2010-06-08 | Btg International Ltd. | Therapeutic foam |
| US7842282B2 (en) | 2000-11-24 | 2010-11-30 | Btg International Limited | Generation of therapeutic microfoam |
| US8048439B2 (en) | 2003-11-17 | 2011-11-01 | Btg International Ltd. | Therapeutic foam |
| US8263580B2 (en) | 1998-09-11 | 2012-09-11 | Stiefel Research Australia Pty Ltd | Vitamin formulation |
| US8512680B2 (en) | 2001-08-08 | 2013-08-20 | Btg International Ltd. | Injectables in foam, new pharmaceutical applications |
| US8629128B2 (en) | 2005-06-01 | 2014-01-14 | Stiefel West Coast, Llc | Vitamin formulation |
| US8703827B2 (en) | 2005-05-13 | 2014-04-22 | Btg International Ltd. | Therapeutic foam |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0395329A2 (en) * | 1989-04-26 | 1990-10-31 | Smith Kline & French Laboratories Limited | composition in the form of a foam containing 5-aminosalicylic acid for intra-rectal administration |
| EP0423695A2 (en) * | 1989-10-19 | 1991-04-24 | Sterling Drug Inc. | Aerosol composition for topical medicament |
| US5059187A (en) * | 1988-11-30 | 1991-10-22 | Dey Laboratories, Inc. | Method for the cleansing of wounds using an aerosol container having liquid wound cleansing solution |
| WO1992011839A1 (en) * | 1991-01-08 | 1992-07-23 | Leonard Mackles | Anhydrous aerosol |
| US5143717A (en) * | 1987-12-30 | 1992-09-01 | Code Blue Medical Corporation | Burn foam and delivery system |
| US5322683A (en) * | 1989-05-01 | 1994-06-21 | Leonard Mackles | Anhydrous aerosol foam |
-
1995
- 1995-02-17 GB GBGB9503119.1A patent/GB9503119D0/en active Pending
-
1996
- 1996-02-12 WO PCT/GB1996/000292 patent/WO1996025194A1/en active Application Filing
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5143717A (en) * | 1987-12-30 | 1992-09-01 | Code Blue Medical Corporation | Burn foam and delivery system |
| US5059187A (en) * | 1988-11-30 | 1991-10-22 | Dey Laboratories, Inc. | Method for the cleansing of wounds using an aerosol container having liquid wound cleansing solution |
| EP0395329A2 (en) * | 1989-04-26 | 1990-10-31 | Smith Kline & French Laboratories Limited | composition in the form of a foam containing 5-aminosalicylic acid for intra-rectal administration |
| US5322683A (en) * | 1989-05-01 | 1994-06-21 | Leonard Mackles | Anhydrous aerosol foam |
| EP0423695A2 (en) * | 1989-10-19 | 1991-04-24 | Sterling Drug Inc. | Aerosol composition for topical medicament |
| WO1992011839A1 (en) * | 1991-01-08 | 1992-07-23 | Leonard Mackles | Anhydrous aerosol |
Non-Patent Citations (1)
| Title |
|---|
| DATABASE WPI Derwent World Patents Index; * |
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE40640E1 (en) | 1993-06-23 | 2009-02-17 | Btg International Ltd. | Injectable microfoam containing a sclerosing agent |
| USRE38919E1 (en) | 1993-06-23 | 2005-12-13 | Btg International Limited | Injectable microfoam containing a sclerosing agent |
| US8263580B2 (en) | 1998-09-11 | 2012-09-11 | Stiefel Research Australia Pty Ltd | Vitamin formulation |
| US8091801B2 (en) | 1999-05-26 | 2012-01-10 | Btg International Limited | Generation of therapeutic microfoam |
| US7025290B2 (en) | 1999-05-26 | 2006-04-11 | Btg International Limited | Generation of therapeutic microfoam |
| US7604185B2 (en) | 1999-05-26 | 2009-10-20 | Btg International Ltd. | Generation of therapeutic microfoam |
| US7357336B2 (en) | 1999-05-26 | 2008-04-15 | Btg International Limited | Generation of therapeutic microfoam |
| GB2353214A (en) * | 1999-07-06 | 2001-02-21 | Cooper John Philip | Topical Composition |
| US7842283B2 (en) | 2000-11-24 | 2010-11-30 | Btg International Limited | Generation of therapeutic microfoam |
| US7842282B2 (en) | 2000-11-24 | 2010-11-30 | Btg International Limited | Generation of therapeutic microfoam |
| WO2002062420A1 (en) * | 2001-01-22 | 2002-08-15 | SØRENSEN, Svein | Photodynamic stimulation device and methods |
| US8512680B2 (en) | 2001-08-08 | 2013-08-20 | Btg International Ltd. | Injectables in foam, new pharmaceutical applications |
| US8048439B2 (en) | 2003-11-17 | 2011-11-01 | Btg International Ltd. | Therapeutic foam |
| US7763269B2 (en) | 2003-11-17 | 2010-07-27 | Btg International Ltd. | Therapeutic foam |
| US7731986B2 (en) | 2003-11-17 | 2010-06-08 | Btg International Ltd. | Therapeutic foam |
| US8323677B2 (en) | 2003-11-17 | 2012-12-04 | Btg International Ltd. | Therapeutic foam |
| US8703827B2 (en) | 2005-05-13 | 2014-04-22 | Btg International Ltd. | Therapeutic foam |
| US8629128B2 (en) | 2005-06-01 | 2014-01-14 | Stiefel West Coast, Llc | Vitamin formulation |
Also Published As
| Publication number | Publication date |
|---|---|
| GB9503119D0 (en) | 1995-04-05 |
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