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WO1996011664A3 - NSK2 a muscle receptor tyrosine kinase - Google Patents

NSK2 a muscle receptor tyrosine kinase Download PDF

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Publication number
WO1996011664A3
WO1996011664A3 PCT/US1995/013490 US9513490W WO9611664A3 WO 1996011664 A3 WO1996011664 A3 WO 1996011664A3 US 9513490 W US9513490 W US 9513490W WO 9611664 A3 WO9611664 A3 WO 9611664A3
Authority
WO
WIPO (PCT)
Prior art keywords
receptor tyrosine
nsk2
tyrosine kinase
muscle receptor
muscle
Prior art date
Application number
PCT/US1995/013490
Other languages
French (fr)
Other versions
WO1996011664A2 (en
Inventor
Alastair Reith
Original Assignee
Ludwig Inst Cancer Res
Alastair Reith
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9420389A external-priority patent/GB9420389D0/en
Priority claimed from GBGB9510574.8A external-priority patent/GB9510574D0/en
Application filed by Ludwig Inst Cancer Res, Alastair Reith filed Critical Ludwig Inst Cancer Res
Priority to JP51346396A priority Critical patent/JP2002517166A/en
Priority to EP95943567A priority patent/EP0800531A4/en
Priority to AU45006/96A priority patent/AU4500696A/en
Publication of WO1996011664A2 publication Critical patent/WO1996011664A2/en
Publication of WO1996011664A3 publication Critical patent/WO1996011664A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4716—Muscle proteins, e.g. myosin, actin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

A novel family of receptor tyrosine kinases is disclosed. The nucleic acid molecules encoding them, and the uses of these, are features of the disclosed invention.
PCT/US1995/013490 1994-10-10 1995-10-10 Nsk2 a muscle receptor tyrosine kinase WO1996011664A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP51346396A JP2002517166A (en) 1994-10-10 1995-10-10 Novel receptor tyrosine kinase
EP95943567A EP0800531A4 (en) 1994-10-10 1995-10-10 NEW RECEPTORS WITH TYROSINE KINASE ACTIVITY
AU45006/96A AU4500696A (en) 1994-10-10 1995-10-10 Novel receptor tyrosine kinases

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9420389A GB9420389D0 (en) 1994-10-10 1994-10-10 Novel receptor tyrosine kinase
GB9420389.0 1994-10-10
GBGB9510574.8A GB9510574D0 (en) 1995-05-24 1995-05-24 Novel receptor tyrosine kinases
GB9510574.8 1995-05-24

Publications (2)

Publication Number Publication Date
WO1996011664A2 WO1996011664A2 (en) 1996-04-25
WO1996011664A3 true WO1996011664A3 (en) 1996-07-04

Family

ID=26305770

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/013490 WO1996011664A2 (en) 1994-10-10 1995-10-10 Nsk2 a muscle receptor tyrosine kinase

Country Status (4)

Country Link
EP (1) EP0800531A4 (en)
JP (1) JP2002517166A (en)
AU (1) AU4500696A (en)
WO (1) WO1996011664A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681714A (en) * 1992-07-30 1997-10-28 Mount Sinai Hospital Corporation Nucleic acid encoding tek receptor tyrosine kinase
AU7521196A (en) * 1995-10-27 1997-05-15 Asahi Chemical Industry Co. Ltd. Peptide inhibitors of a phosphotyrosine-binding domain containing protein
US6028053A (en) * 1995-10-27 2000-02-22 Mount Sinai Hospital Corporation Peptide inhibitors of a phosphotyrosine-binding domain containing protein

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2963395A (en) * 1994-07-20 1996-02-16 Genetics Institute Inc. Mlk receptor tyrosine kinases
JPH10505489A (en) * 1994-07-20 1998-06-02 リジェネロン ファーマシューティカルズ， インコーポレイテッド Denervated muscle kinase (DMK), tyrosine kinase superfamily receptor

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
MAMMALIAN GENOMICS, Vol. 6, No. 9, issued September 1995, REITH, "Isolation and Chromosomal Location of Nsk1, a Novel Murine Putative Receptor Tyrosine Kinase", page 689. *
ONCOGENE, Vol. 11, No. 2, issued 26 April 1995, GANJU et al., "Cloning and Developmental Expression of Nsk2, a Novel Receptor Tyrosine Kinase Implicated in Skeletal Myogenesis", pages 281-290. *
PROC. NATL. ACAD. SCI. U.S.A., Vol. 86, issued March 1989, WILKS, "Two Putative Protein-Tyrosine Kinases Identified by Application of the Polymerase Chain Reaction", pages 1603-1607. *
PROC. NATL. ACAD. SCI. U.S.A., Vol. 90, issued April 1993, JENNINGS et al., "Muscle-specific trk Related Receptor with a Kringle Domain Defines a Distinct Class of Receptor Tyrosine Kinases", pages 2895-2899. *
See also references of EP0800531A4 *

Also Published As

Publication number Publication date
EP0800531A2 (en) 1997-10-15
AU4500696A (en) 1996-05-06
EP0800531A4 (en) 1999-09-22
JP2002517166A (en) 2002-06-11
WO1996011664A2 (en) 1996-04-25

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