WO1996003413B1 - Sulfatation regioselective - Google Patents
Sulfatation regioselectiveInfo
- Publication number
- WO1996003413B1 WO1996003413B1 PCT/EP1995/003034 EP9503034W WO9603413B1 WO 1996003413 B1 WO1996003413 B1 WO 1996003413B1 EP 9503034 W EP9503034 W EP 9503034W WO 9603413 B1 WO9603413 B1 WO 9603413B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- organic molecule
- regioselective
- sulfation
- regioselective sulfation
- hereinabove
- Prior art date
Links
- 230000019635 sulfation Effects 0.000 title abstract 2
- 238000005670 sulfation reaction Methods 0.000 title abstract 2
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- -1 stannylene acetal Chemical class 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
- 230000001180 sulfating effect Effects 0.000 abstract 1
Abstract
L'invention concerne entre autres un procédé direct de sulfatation régiosélective d'une molécule organique ayant éventuellement des groupes dérivés hydroxyle au moins sur deux atomes de carbone adjacents, et se caractérisant en ce qu'il comprend le traitement d'un dérivé d'acétal de stannylène di(alkyle et/ou aryle éventuellement substitué) avec un agent de sulfatation électrophile.
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU32236/95A AU704248B2 (en) | 1994-07-27 | 1995-07-27 | Regioselective sulfation |
| US08/765,930 US5874548A (en) | 1994-07-27 | 1995-07-27 | Regioselective sulfation |
| AT95928469T ATE215550T1 (de) | 1994-07-27 | 1995-07-27 | Regioselektive sulfatierung |
| JP8505494A JPH10502093A (ja) | 1994-07-27 | 1995-07-27 | レジオ選択的硫酸化 |
| EP95928469A EP0772618B1 (fr) | 1994-07-27 | 1995-07-27 | Sulfatation regioselective |
| DE69526228T DE69526228T2 (de) | 1994-07-27 | 1995-07-27 | Regioselektive sulfatierung |
| DK95928469T DK0772618T3 (da) | 1994-07-27 | 1995-07-27 | Regioselektiv sulfatering |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9415169A GB9415169D0 (en) | 1994-07-27 | 1994-07-27 | Regioselective sulfation |
| GB9415169.3 | 1994-11-04 | ||
| GB9422304A GB9422304D0 (en) | 1994-11-04 | 1994-11-04 | Regioselective sulfation |
| GB9422304.7 | 1994-11-04 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| WO1996003413A2 WO1996003413A2 (fr) | 1996-02-08 |
| WO1996003413A3 WO1996003413A3 (fr) | 1996-07-18 |
| WO1996003413B1 true WO1996003413B1 (fr) | 1996-08-29 |
Family
ID=26305346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/EP1995/003034 WO1996003413A2 (fr) | 1994-07-27 | 1995-07-27 | Sulfatation regioselective |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5874548A (fr) |
| EP (1) | EP0772618B1 (fr) |
| JP (1) | JPH10502093A (fr) |
| AT (1) | ATE215550T1 (fr) |
| AU (1) | AU704248B2 (fr) |
| CA (1) | CA2194492A1 (fr) |
| DE (1) | DE69526228T2 (fr) |
| DK (1) | DK0772618T3 (fr) |
| ES (1) | ES2174955T3 (fr) |
| PT (1) | PT772618E (fr) |
| WO (1) | WO1996003413A2 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998037902A1 (fr) * | 1997-02-28 | 1998-09-03 | The Regents Of The University Of California | Inhibition de la liaison entre cellules au moyen d'ensembles lipidiques |
| US6184196B1 (en) | 1998-05-27 | 2001-02-06 | University Of Iowa Research Foundation | Sucrose based surfactants and methods thereof |
| US6239584B1 (en) * | 2000-06-20 | 2001-05-29 | Delta Electronics, Inc. | Two-inductor boost converter |
| CA2458651C (fr) * | 2001-08-31 | 2011-11-29 | Ivax Research, Inc. | Procedes de sulfatation de saccharides |
| KR20060129296A (ko) * | 2003-12-23 | 2006-12-15 | 프로젠 인더스트리즈 리미티드 | 글리코사미노글리칸(ｇａｇ) 모방체 |
| WO2007038785A1 (fr) * | 2005-09-29 | 2007-04-05 | Torrey Pines Institute For Molecular Studies | Sulfatides pour traiter des troubles auto-immuns |
| JP5657567B2 (ja) * | 2009-01-12 | 2015-01-21 | ユニヴァーシティ オブ ワシントン | 配糖体の２−硫酸化方法 |
| WO2014205115A2 (fr) | 2013-06-19 | 2014-12-24 | The Regents Of The University Of California | Échange de silyle régiosélectif d'oligosaccharides per-silylés |
| ITUB20155623A1 (it) * | 2015-11-16 | 2017-05-16 | Fidia Farm Spa | Processo migliorato per la produzione di HA solfatato di elevata purezza |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69023408T2 (de) * | 1989-07-27 | 1996-05-02 | Monsanto Co | Glykosidasehemmende Piperidinverbindungen. |
| JPH07110872B2 (ja) * | 1990-09-25 | 1995-11-29 | 株式会社ディ・ディ・エス研究所 | 酸性糖脂質及び微粒子キャリヤー |
| GB9207182D0 (en) * | 1992-04-01 | 1992-05-13 | Enzymatix Ltd | Glycolipids and their preparation |
| US5620864A (en) * | 1992-06-29 | 1997-04-15 | Health Research, Inc. | Acceptor for fucosyl transferase |
-
1995
- 1995-07-27 DE DE69526228T patent/DE69526228T2/de not_active Expired - Fee Related
- 1995-07-27 AU AU32236/95A patent/AU704248B2/en not_active Ceased
- 1995-07-27 EP EP95928469A patent/EP0772618B1/fr not_active Expired - Lifetime
- 1995-07-27 JP JP8505494A patent/JPH10502093A/ja active Pending
- 1995-07-27 ES ES95928469T patent/ES2174955T3/es not_active Expired - Lifetime
- 1995-07-27 US US08/765,930 patent/US5874548A/en not_active Expired - Fee Related
- 1995-07-27 AT AT95928469T patent/ATE215550T1/de not_active IP Right Cessation
- 1995-07-27 WO PCT/EP1995/003034 patent/WO1996003413A2/fr active IP Right Grant
- 1995-07-27 CA CA002194492A patent/CA2194492A1/fr not_active Abandoned
- 1995-07-27 PT PT95928469T patent/PT772618E/pt unknown
- 1995-07-27 DK DK95928469T patent/DK0772618T3/da active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR029181A1 (es) | Procedimiento regioselectivo de derivados de rapamicina y compuestos intermediarios de 31-silil eter | |
| ID22994A (id) | Senyawa aminoalkil glikosamina fosfat dan penggunaannya sebagai adjuvan dan pemicu kekebalan | |
| NZ331824A (en) | use of an unsaturated fatty alcohol to stabilise a macrolide in a pharmaceutical composition | |
| AU6969796A (en) | Body wash composition to impart conditioning properties to skin | |
| IL86881A (en) | Polysaccharides extracted from plants,their preparation and pharmaceutical compositions containing them | |
| CA2122930A1 (fr) | Fractions d'heparine purifiees, methode pour les obtenir et compositions pharmaceutiques en contenant | |
| WO1996003413B1 (fr) | Sulfatation regioselective | |
| CA2253833A1 (fr) | Derives de polysaccharide k5 ayant une activite anticoagulante elevee | |
| CA2115745A1 (fr) | Ethers sans ester | |
| DE69322265D1 (en) | Alkylthioalkylavermectine sind aktive antiparasitäre wirkstoffe | |
| EP0957107A4 (fr) | ||
| CA2248032A1 (fr) | Agent abaissant le taux de cholesterol dans le serum | |
| ATE210673T1 (de) | Glycokonjugate von modifizierten camptothecin- derivaten (20-o-verknüpfung) | |
| WO1996003413A3 (fr) | Sulfatation regioselective | |
| ATE154615T1 (de) | Halbsynthetische glykosaminoglykane, die in 3- position mit nukleophilen radikalen substituierte alpha-l-galakturonsäure enthalten | |
| Colombo et al. | Distribution Of The Ace, Zot, And Ctxa Toxin Genes In Clinical And Environmental Vibrio Cholerae [X] | |
| AU3969593A (en) | Parenteral solutions containing 3-dialkylaminoethoxybenzoyl-benzofurans | |
| AU629966B2 (en) | A microorganism for selective production of specific component of avermectin and a method for selective production thereof | |
| AU2001246510A1 (en) | Glycosaminoglycans derived from the k5 polysaccharide having high anticoagulant and antithrombotic activity and process for their preparation | |
| EP0475383A3 (en) | Polysaccharide composition or polysaccharide having heparinoid activity, process for producing the same, and anticoagulant containing the same as active ingredient | |
| EA199800778A1 (ru) | Способ окисления полисахарида | |
| ID28892A (id) | Sintesa heteropoliasida | |
| IT1264102B1 (it) | Processo per la sintesi di glicosaminoglicani semisintetici contenenti acido alfa-l-galatturonico sostituito con radicali | |
| AU4941693A (en) | Impregnating agent for producing papers with high resistance to the penetration of grease, oil and aqueous media | |
| ES2119077T3 (es) | Aislamiento y estructura de la esponjistatina 1 y su empleo como agente antitumoral. |