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WO1996040760A3 - Peptides iodes et leur utilisation comme opacifiants radiologiques - Google Patents

Peptides iodes et leur utilisation comme opacifiants radiologiques Download PDF

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Publication number
WO1996040760A3
WO1996040760A3 PCT/EP1996/002450 EP9602450W WO9640760A3 WO 1996040760 A3 WO1996040760 A3 WO 1996040760A3 EP 9602450 W EP9602450 W EP 9602450W WO 9640760 A3 WO9640760 A3 WO 9640760A3
Authority
WO
WIPO (PCT)
Prior art keywords
iodine
contrast media
containing peptides
ray contrast
compounds
Prior art date
Application number
PCT/EP1996/002450
Other languages
English (en)
Other versions
WO1996040760A2 (fr
Inventor
Werner Krause
Danute Nitecki
Franz Maier
Gabriele Schumann-Giampieri
Wolf-Ruediger Press
Peter Muschick
Sara Biancalana
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Priority to EP96921933A priority Critical patent/EP0835259A1/fr
Publication of WO1996040760A2 publication Critical patent/WO1996040760A2/fr
Publication of WO1996040760A3 publication Critical patent/WO1996040760A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0442—Polymeric X-ray contrast-enhancing agent comprising a halogenated group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention se rapporte à des peptides iodés de formule générale (I), dans laquelle R?1, R2, R3, R4¿, a, m et q sont tels que décrits dans la description, à des agents contenant ces composés, à l'utilisation de ces composés comme opacifiants radiologiques, ainsi qu'à leurs procédés de production.
PCT/EP1996/002450 1995-06-07 1996-06-06 Peptides iodes et leur utilisation comme opacifiants radiologiques WO1996040760A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP96921933A EP0835259A1 (fr) 1995-06-07 1996-06-06 Peptides iodes et leur utilisation comme opacifiants radiologiques

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/487,096 US5756066A (en) 1995-06-07 1995-06-07 Iodine-containing peptides
US08/487,096 1995-06-07

Publications (2)

Publication Number Publication Date
WO1996040760A2 WO1996040760A2 (fr) 1996-12-19
WO1996040760A3 true WO1996040760A3 (fr) 1997-02-06

Family

ID=23934398

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1996/002450 WO1996040760A2 (fr) 1995-06-07 1996-06-06 Peptides iodes et leur utilisation comme opacifiants radiologiques

Country Status (4)

Country Link
US (1) US5756066A (fr)
EP (1) EP0835259A1 (fr)
CA (1) CA2223924A1 (fr)
WO (1) WO1996040760A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998032469A2 (fr) * 1997-01-29 1998-07-30 Nycomed Imaging As Polymeres
EP0885616A1 (fr) * 1997-06-20 1998-12-23 Schering Aktiengesellschaft Utilisation d'agents de contraste à administration intraveneuse, et appareil pour la mammographie
WO2000015645A1 (fr) * 1998-09-11 2000-03-23 Kyorin Pharmaceutical Co., Ltd. Derives d'esters phosphoniques et leur procede de production
US20060292077A1 (en) * 2005-03-18 2006-12-28 Zhao Jonathon Z Dendritic and star-shaped contrast agents for medical devices and bioabsorbable radiopaque bulk material and method for producing same
WO2013137302A1 (fr) * 2012-03-13 2013-09-19 国立大学法人 岡山大学 Dérivé d'oligomère de lysine et marqueur de tissu cartilagineux fabriqué à partir de celui- ci

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0512661A1 (fr) * 1991-05-10 1992-11-11 Schering Aktiengesellschaft Polymère-complexants macrocycliques, leur complexes, procédé pour leur préparation et agents pharmaceutiques les contenant
WO1993010824A1 (fr) * 1991-12-04 1993-06-10 Guerbet S.A. Nouveau compose macromoleculaire polyamine iode, son procede de preparation et son utilisation comme agent de contraste
WO1994021600A1 (fr) * 1993-03-22 1994-09-29 Guerbet S.A. Nouveaux composes polyiodes, leur preparation et leur utilisation en tant que produits de contraste pour la radiologie
WO1995017448A2 (fr) * 1993-12-22 1995-06-29 Schering Aktiengesellschaft Polymeres en cascade a composes aromatiques d'iode

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61272201A (ja) * 1985-05-28 1986-12-02 Tetsuo Suami ６−ヨ−ドエチル化澱粉およびその製法
FR2610935B1 (fr) * 1987-02-13 1989-09-01 Guerbet Sa Polymeres iodes, leurs procedes de preparation et leurs applications comme produits de contraste
US5229490A (en) * 1987-05-06 1993-07-20 The Rockefeller University Multiple antigen peptide system
CA2031739A1 (fr) * 1989-12-08 1991-06-09 Milos Sovak Produit de contraste pour rayons x destine au tractus gastro-intestinal

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0512661A1 (fr) * 1991-05-10 1992-11-11 Schering Aktiengesellschaft Polymère-complexants macrocycliques, leur complexes, procédé pour leur préparation et agents pharmaceutiques les contenant
WO1993010824A1 (fr) * 1991-12-04 1993-06-10 Guerbet S.A. Nouveau compose macromoleculaire polyamine iode, son procede de preparation et son utilisation comme agent de contraste
WO1994021600A1 (fr) * 1993-03-22 1994-09-29 Guerbet S.A. Nouveaux composes polyiodes, leur preparation et leur utilisation en tant que produits de contraste pour la radiologie
WO1995017448A2 (fr) * 1993-12-22 1995-06-29 Schering Aktiengesellschaft Polymeres en cascade a composes aromatiques d'iode

Also Published As

Publication number Publication date
WO1996040760A2 (fr) 1996-12-19
CA2223924A1 (fr) 1996-12-19
US5756066A (en) 1998-05-26
EP0835259A1 (fr) 1998-04-15

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