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WO1995022609A3 - Human glutamate receptor proteins - Google Patents

Human glutamate receptor proteins Download PDF

Info

Publication number
WO1995022609A3
WO1995022609A3 PCT/GB1995/000356 GB9500356W WO9522609A3 WO 1995022609 A3 WO1995022609 A3 WO 1995022609A3 GB 9500356 W GB9500356 W GB 9500356W WO 9522609 A3 WO9522609 A3 WO 9522609A3
Authority
WO
WIPO (PCT)
Prior art keywords
glutamate receptor
receptor proteins
human
human glutamate
receptors
Prior art date
Application number
PCT/GB1995/000356
Other languages
French (fr)
Other versions
WO1995022609A2 (en
Inventor
Andrew Joseph Makoff
Original Assignee
Wellcome Found
Andrew Joseph Makoff
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9403285A external-priority patent/GB9403285D0/en
Priority claimed from GB9415532A external-priority patent/GB9415532D0/en
Application filed by Wellcome Found, Andrew Joseph Makoff filed Critical Wellcome Found
Publication of WO1995022609A2 publication Critical patent/WO1995022609A2/en
Publication of WO1995022609A3 publication Critical patent/WO1995022609A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention provides human metabotropic glutamate receptors 3 and 4 (human mGluR3 and human mGluR4), DNAs encoding the receptors and a method for screening for compounds which bind to or modulate the activity of the receptors.
PCT/GB1995/000356 1994-02-21 1995-02-21 Human glutamate receptor proteins WO1995022609A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9403285A GB9403285D0 (en) 1994-02-21 1994-02-21 Human glutamate receptor protein
GB9403285.1 1994-02-21
GB9415532A GB9415532D0 (en) 1994-08-01 1994-08-01 Human glutamate receptor protein
GB9415532.2 1994-08-01

Publications (2)

Publication Number Publication Date
WO1995022609A2 WO1995022609A2 (en) 1995-08-24
WO1995022609A3 true WO1995022609A3 (en) 1995-09-08

Family

ID=26304369

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1995/000356 WO1995022609A2 (en) 1994-02-21 1995-02-21 Human glutamate receptor proteins

Country Status (1)

Country Link
WO (1) WO1995022609A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912122A (en) * 1993-06-04 1999-06-15 Sibia Neurosciences, Inc. Nucleic acids encoding and method for detecting nucleic acid encoding human metabotropic glutamate receptor subtype mGluR6
US6228610B1 (en) 1993-09-20 2001-05-08 Novartis Corporation Human metabotropic glutamate receptor subtypes (hmR4, hmR6, hmR7) and related DNA compounds
US6384205B1 (en) * 1996-03-12 2002-05-07 Eli Lilly And Company Metabotropic glutamate receptor 4 nucleic acid
WO1999021992A2 (en) * 1997-10-23 1999-05-06 Ganimed Pharmaceuticals Gmbh Nucleic acid molecules encoding a glutamate receptor
US7262280B1 (en) 1998-04-03 2007-08-28 Nps Pharmaceuticals, Inc. G-protein fusion receptors and constructs encoding same
WO2005069010A1 (en) * 2004-01-19 2005-07-28 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with human metabotropic glutamate receptor 4 (mglur4)
CN115960230A (en) 2015-08-07 2023-04-14 伊麦吉纳博公司 Antigen-binding constructs targeting molecules
US11266745B2 (en) 2017-02-08 2022-03-08 Imaginab, Inc. Extension sequences for diabodies

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992010583A1 (en) * 1990-12-12 1992-06-25 Zymogenetics, Inc. G protein-coupled glutamate receptors
WO1994029449A1 (en) * 1993-06-04 1994-12-22 The Salk Institute Biotechnology/Industrial Associates, Inc. Human metabotropic glutamate receptors, nucleic acids encoding same and uses thereof
WO1995008627A1 (en) * 1993-09-20 1995-03-30 Ciba-Geigy Ag Human metabotropic glutamate receptor subtypes (hmr4, hmr6, hmr7) and related dna compounds

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992010583A1 (en) * 1990-12-12 1992-06-25 Zymogenetics, Inc. G protein-coupled glutamate receptors
WO1994029449A1 (en) * 1993-06-04 1994-12-22 The Salk Institute Biotechnology/Industrial Associates, Inc. Human metabotropic glutamate receptors, nucleic acids encoding same and uses thereof
WO1995008627A1 (en) * 1993-09-20 1995-03-30 Ciba-Geigy Ag Human metabotropic glutamate receptor subtypes (hmr4, hmr6, hmr7) and related dna compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Y. TANABE ET AL: "A family of metabotropic glutamate receptors", NEURON, vol. 8, January 1992 (1992-01-01), pages 169 - 179 *

Also Published As

Publication number Publication date
WO1995022609A2 (en) 1995-08-24

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