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WO1995012682A3 - Vecteur viral a antigenes du virus de la maladie des muqueuses (bvdv) - Google Patents

Vecteur viral a antigenes du virus de la maladie des muqueuses (bvdv) Download PDF

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Publication number
WO1995012682A3
WO1995012682A3 PCT/US1994/012198 US9412198W WO9512682A3 WO 1995012682 A3 WO1995012682 A3 WO 1995012682A3 US 9412198 W US9412198 W US 9412198W WO 9512682 A3 WO9512682 A3 WO 9512682A3
Authority
WO
WIPO (PCT)
Prior art keywords
bvdv
antigens
diarrhea virus
virus
bovine
Prior art date
Application number
PCT/US1994/012198
Other languages
English (en)
Other versions
WO1995012682A2 (fr
Inventor
Elizabeth J Haanes
Richard C Wardley
Original Assignee
Upjohn Co
Elizabeth J Haanes
Richard C Wardley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co, Elizabeth J Haanes, Richard C Wardley filed Critical Upjohn Co
Priority to JP7513263A priority Critical patent/JPH09504435A/ja
Priority to EP95901037A priority patent/EP0725831A1/fr
Priority to NZ276234A priority patent/NZ276234A/en
Priority to KR1019960702343A priority patent/KR960705944A/ko
Priority to AU10423/95A priority patent/AU688819B2/en
Publication of WO1995012682A2 publication Critical patent/WO1995012682A2/fr
Publication of WO1995012682A3 publication Critical patent/WO1995012682A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16641—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Cette invention se rapporte au virus de la maladie des muqueuses (BVDV) et à des vaccins utilisés dans le traitement de cette maladie. Cette invention concerne la préparation de l'herpèsvirus des bovins vivants atténués, de type 1 (BHV-1), sous forme d'un virus, d'un vaccin et d'un vecteur d'expression des antigènes de BVDV. Un clone d'ADNc du BVDV contenant des séquences correspondant à la glycoprotéine gp53 est inséré dans un virus BHV-1 inactivé.
PCT/US1994/012198 1993-11-05 1994-10-31 Vecteur viral a antigenes du virus de la maladie des muqueuses (bvdv) WO1995012682A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP7513263A JPH09504435A (ja) 1993-11-05 1994-10-31 ウシウイルス性下痢ウイルス（ｂｖｄｖ）抗原を有するウイルスベクター
EP95901037A EP0725831A1 (fr) 1993-11-05 1994-10-31 Vecteur viral a antigenes du virus de la maladie des muqueuses (bvdv)
NZ276234A NZ276234A (en) 1993-11-05 1994-10-31 An attenuated replicating non pathogenic flavivirus (bovine viral diarrhoea virus - bvdv) vaccine
KR1019960702343A KR960705944A (ko) 1993-11-05 1994-10-31 소 바이러스성 설사 바이러스(bvdv) 항원을 갖는 바이러스 벡터(viral vector with bovine viral diarrhea virus(bvdv)antigens)
AU10423/95A AU688819B2 (en) 1993-11-05 1994-10-31 Viral vector with bovine viral diarrhea virus (BVDV) antigens

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14781093A 1993-11-05 1993-11-05
US08/147,810 1993-11-05

Publications (2)

Publication Number Publication Date
WO1995012682A2 WO1995012682A2 (fr) 1995-05-11
WO1995012682A3 true WO1995012682A3 (fr) 1995-07-06

Family

ID=22522990

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1994/012198 WO1995012682A2 (fr) 1993-11-05 1994-10-31 Vecteur viral a antigenes du virus de la maladie des muqueuses (bvdv)

Country Status (9)

Country Link
EP (1) EP0725831A1 (fr)
JP (1) JPH09504435A (fr)
KR (1) KR960705944A (fr)
CN (1) CN1134175A (fr)
AU (1) AU688819B2 (fr)
CA (1) CA2172815A1 (fr)
MX (1) MXPA94008605A (fr)
NZ (1) NZ276234A (fr)
WO (1) WO1995012682A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6060457A (en) * 1996-06-20 2000-05-09 Universite De Montreal DNA plasmid vaccine for immunization of animals against BVDV
RU2158306C2 (ru) * 1999-01-19 2000-10-27 Институт экспериментальной ветеринарии Сибири и Дальнего Востока СО РАСХН Способ выявления вируса вирусной диареи (болезни слизистых оболочек) крупного рогатого скота с помощью специфических олигонуклеотидных праймеров в полимеразной цепной реакции
EP1026252A1 (fr) * 1999-02-02 2000-08-09 Akzo Nobel N.V. Gène synthétique du virus de la diarrhée virale des bovins
EP1104676A1 (fr) * 1999-11-30 2001-06-06 Boehringer Ingelheim Vetmedica Gmbh Virus de la diarrhée des bovins surs attenués pour utilisation chez des vaches gravides
KR100331176B1 (ko) * 1999-12-15 2002-04-06 대한민국(관리청:특허청장, 승계청:국립수의과학검역원장) 재조합 단백질을 항원으로 이용한 소 바이러스성 설사증의진단방법
EP2365082A1 (fr) * 2000-06-27 2011-09-14 Pfizer Animal Health S.A. Particules de type viral du BVDV
BR0313806A (pt) 2002-08-26 2005-07-05 Pfizer Prod Inc Vacinas para infecções nos sistemas respiratório e reprodutor em gado
JP2007516968A (ja) * 2003-12-05 2007-06-28 ベクトン・ディキンソン・アンド・カンパニー 皮内コンパートメントにおける免疫応答を増強する方法、およびそれらの方法で有用な化合物
KR101876535B1 (ko) * 2012-06-14 2018-07-09 베트올 (주) 소바이러스성 설사병 바이러스의 탐지용 항체, 이를 이용한 항원 검출 방법, 및 이를 포함하는 탐지키트
WO2014151401A1 (fr) 2013-03-15 2014-09-25 Zoetis Llc Protection croisée de bovins contre une infection par b. trehalosi par un vaccin multivalent
CN113913461A (zh) * 2021-11-15 2022-01-11 贵州大学 牛病毒性腹泻e0-e2基因重组腺病毒疫苗构建方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0119025A2 (fr) * 1983-02-25 1984-09-19 Baylor College of Medicine Mutant d'herpès virus-1 bovin thymidine kinase négatif résistant à la température, comme vaccin contre la rhinotrachéite infectieuse bovine
WO1990001337A1 (fr) * 1988-08-03 1990-02-22 Institute For Animal Health Limited Vaccin
EP0464010A1 (fr) * 1990-06-08 1992-01-02 Statens Veterinärmedicinska Anstalt Procédé pour la détection d'une infection due à un virus, d'un type spécifique, des amorces, des sondes et trousse d'essai
WO1994000586A2 (fr) * 1992-06-26 1994-01-06 Rhône Merieux Mutants et vaccins du virus de la rhinotracheite infectieuse bovine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0119025A2 (fr) * 1983-02-25 1984-09-19 Baylor College of Medicine Mutant d'herpès virus-1 bovin thymidine kinase négatif résistant à la température, comme vaccin contre la rhinotrachéite infectieuse bovine
WO1990001337A1 (fr) * 1988-08-03 1990-02-22 Institute For Animal Health Limited Vaccin
EP0464010A1 (fr) * 1990-06-08 1992-01-02 Statens Veterinärmedicinska Anstalt Procédé pour la détection d'une infection due à un virus, d'un type spécifique, des amorces, des sondes et trousse d'essai
WO1994000586A2 (fr) * 1992-06-26 1994-01-06 Rhône Merieux Mutants et vaccins du virus de la rhinotracheite infectieuse bovine

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BELLO, L. ET AL.: "Bovine herpesvirus 1 as a live virus vector for expression of foreign genes", VIROLOGY, vol. 190, no. 2, 1992, pages 666 - 673 *
PATON, D.J. ET AL.: "Epitope mapping of the gp53 envelope protein of bovine viral diarrhea virus", VIROLOGY, vol. 190, no. 2, 1992, pages 763 - 772 *
YU, M. ET AL.: "High level expression of the envelope glycoprotein (GP53) of bovine viral diarrhoea virus (singer) and its potential use as diagnostic reagent", VIRUS RESEARCH, vol. 34, no. 2, 1994, pages 178 - 186 *

Also Published As

Publication number Publication date
EP0725831A1 (fr) 1996-08-14
MXPA94008605A (es) 2004-11-11
NZ276234A (en) 1998-01-26
AU1042395A (en) 1995-05-23
JPH09504435A (ja) 1997-05-06
KR960705944A (ko) 1996-11-08
WO1995012682A2 (fr) 1995-05-11
AU688819B2 (en) 1998-03-19
CN1134175A (zh) 1996-10-23
CA2172815A1 (fr) 1995-05-11

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