WO1995011789A1 - Procede d'extraction d'une lentille de contact de son moule - Google Patents
Procede d'extraction d'une lentille de contact de son moule Download PDFInfo
- Publication number
- WO1995011789A1 WO1995011789A1 PCT/US1994/012144 US9412144W WO9511789A1 WO 1995011789 A1 WO1995011789 A1 WO 1995011789A1 US 9412144 W US9412144 W US 9412144W WO 9511789 A1 WO9511789 A1 WO 9511789A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- mold
- contact lens
- lens
- isopropanol
- release
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 35
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims abstract description 34
- 239000000243 solution Substances 0.000 claims description 21
- 230000000717 retained effect Effects 0.000 claims description 10
- 238000004528 spin coating Methods 0.000 claims description 8
- 238000005266 casting Methods 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 239000007864 aqueous solution Substances 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 239000007975 buffered saline Substances 0.000 claims description 4
- 229920001577 copolymer Polymers 0.000 claims description 4
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims description 3
- 230000003068 static effect Effects 0.000 claims description 3
- 230000000887 hydrating effect Effects 0.000 claims description 2
- 239000000178 monomer Substances 0.000 description 8
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 5
- 238000004132 cross linking Methods 0.000 description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 3
- 239000000017 hydrogel Substances 0.000 description 3
- 238000007654 immersion Methods 0.000 description 3
- 229920001223 polyethylene glycol Polymers 0.000 description 3
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- 229940044192 2-hydroxyethyl methacrylate Drugs 0.000 description 2
- 239000002202 Polyethylene glycol Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- QRIMLDXJAPZHJE-UHFFFAOYSA-N 2,3-dihydroxypropyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCC(O)CO QRIMLDXJAPZHJE-UHFFFAOYSA-N 0.000 description 1
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
- 229940095095 2-hydroxyethyl acrylate Drugs 0.000 description 1
- OMIGHNLMNHATMP-UHFFFAOYSA-N 2-hydroxyethyl prop-2-enoate Chemical compound OCCOC(=O)C=C OMIGHNLMNHATMP-UHFFFAOYSA-N 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 150000003926 acrylamides Chemical class 0.000 description 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 150000001735 carboxylic acids Chemical class 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- FXPHJTKVWZVEGA-UHFFFAOYSA-N ethenyl hydrogen carbonate Chemical class OC(=O)OC=C FXPHJTKVWZVEGA-UHFFFAOYSA-N 0.000 description 1
- 229940093476 ethylene glycol Drugs 0.000 description 1
- 150000002334 glycols Chemical class 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- FQPSGWSUVKBHSU-UHFFFAOYSA-N methacrylamide Chemical compound CC(=C)C(N)=O FQPSGWSUVKBHSU-UHFFFAOYSA-N 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 229940088644 n,n-dimethylacrylamide Drugs 0.000 description 1
- YLGYACDQVQQZSW-UHFFFAOYSA-N n,n-dimethylprop-2-enamide Chemical compound CN(C)C(=O)C=C YLGYACDQVQQZSW-UHFFFAOYSA-N 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- FBCQUCJYYPMKRO-UHFFFAOYSA-N prop-2-enyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCC=C FBCQUCJYYPMKRO-UHFFFAOYSA-N 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- UWHCKJMYHZGTIT-UHFFFAOYSA-N tetraethylene glycol Chemical compound OCCOCCOCCOCCO UWHCKJMYHZGTIT-UHFFFAOYSA-N 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- -1 vinyl lactams Chemical class 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
- B29D11/00009—Production of simple or compound lenses
- B29D11/00038—Production of contact lenses
- B29D11/00125—Auxiliary operations, e.g. removing oxygen from the mould, conveying moulds from a storage to the production line in an inert atmosphere
- B29D11/00192—Demoulding, e.g. separating lenses from mould halves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C33/00—Moulds or cores; Details thereof or accessories therefor
- B29C33/56—Coatings, e.g. enameled or galvanised; Releasing, lubricating or separating agents
- B29C33/60—Releasing, lubricating or separating agents
Definitions
- This invention relates to improved methods of processing contact lenses, especially releasing a contact lens from the mold in which the lens was cast.
- Soft contact lenses are produced by several methods including spincasting, static cast molding, and combinations of casting and lathing.
- the lens In production methods using molds, the lens is generally retained on the mold following casting, and it is necessary to release the lens from the mold without damaging the lens.
- One way to release lenses is to place the mold with the lens in water, usually at elevated temperature, wherein the lens is hydrated and released from the mold. This conventional method is discussed in U.S. Serial No. 07/755,201 (filed September 5, 1991) along with a modification wherein a surfactant is included in the hydration bath.
- the invention provides a method of releasing a contact lens from a mold in which the contact lens was cast which comprises contacting the contact lens and the mold with a release solution comprising isopropanol, whereby the contact lens is released from the mold.
- the invention provides a method comprising: casting a contact lens from a polymerizable mixture in a mold, wherein the contact lens is retained in the mold; releasing the contact lens from the mold by contacting the contact lens and the mold with a release solution comprising isopropanol; and subsequently hydrating the contact lens.
- the methods provide release of lenses with good surface properties, clarity and image quality, and improved consistency in the quality of the lenses.
- the release solution of this invention comprises isopropanol. Either pure isopropanol or an aqueous solution of isopropanol may be used. Preferably, the isopropanol content in the solution is at least 25 volume percent, with at least 40 volume percent being especially preferred.
- the release solution may include other components if desired, such as the surfactants disc] sed in U.S. Serial No. 07/755,201 (filed
- Suitable contact lenses include: "hard” lenses such as rigid gas permeable (RGP) contact lenses, formed of silicone acrylate or fluorosilicone acrylate copolymers; and "soft" hydrogel contact lenses. Preferred are the soft hydrogel contact lenses.
- Lenses in this class are generally formed of a copolymer of at least one hydrophilic monomer and a crosslinking monomer.
- Hydrophilic monomers include: unsaturated carboxylic acids, such as methacrylic acid and acrylic acid; (meth)acrylic substituted alcohols or glycols, such as 2-hydroxyethylmethacrylate, 2- hydroxyethylacrylate, glyceryl methacrylate, and polyethyleneglycol methacrylate; vinyl lactams, such as N-vinyl-2-pyrrolidone; and acrylamides, such as methacrylamide and N,N-dimethylacrylamide.
- the crosslinking monomer is a material having multiple polymerizable functionalities, preferably vinyl functionalities.
- crosslinking monomers include: divinylbenzene; allyl methacrylate; ethyleneglycol di(meth)aery] " * te, tetraethyleneglycol di(meth)acrylate, polyethyleneglycol di(meth)acrylate; and vinylcarbonate derivatives of the glycol di(meth)acrylates.
- the copolymeric material further includes a ⁇ ilicone-containing monomer.
- the method can be used for releasing lenses cast by various known methods. These casting methods include spincasting wherein the lens is retained in the spincast mold. Another method is static casting wherein the lens is cast between two mold parts. The release solution may be used to release the lens from both mold parts, however, it is preferred that the casting method results in the lens being selectively retained on one mold part wherein the release solution is used to release the lens from this mold part. A further method is spincasting an excess of monomer by spincasting in a spincasting mold and lathing the posterior surface while the lens is retained in the mold. Following the lathing operation, the lens is released from the mold with the release solution.
- Contact lenses are released by contacting the lens and mold with the release solution, preferably by immersing the mold and lens assembly in the solution.
- the release step may be accomplished at room temperature, although in some cases it may be advantageous to conduct the release at other temperatures, for example, at an elevated temperature up to about 125°C.
- the lens is hydrated with water or buffered saline. Subsequently, the lens is sterilized such as by autoclaving in water or saline. These steps also effect removal of any residual isopropanol from the lens.
- EXAMPLE Contact lenses were obtained as follows. Monomeric mixtures, containing 2-hydroxyethyl methacrylate and a crosslinking monomer, were cured by spincasting in polyvinyl chloride (PVC) molds, followed by lathing the posterior surfaces to obtain contact lenses. The lenses, still retained in the molds, were released by one of the following three conditions: (1) immersion in water at 50°C; (2) immersion in an isopropanol/water mixture (50/50 v/v) at ambient temperature; and (3) immersion in an isopropanol/water mixture (50/50 v/v) at 55°C.
- PVC polyvinyl chloride
- RI refractive index
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Health & Medical Sciences (AREA)
- Manufacturing & Machinery (AREA)
- Ophthalmology & Optometry (AREA)
- Eyeglasses (AREA)
Abstract
Procédé d'extraction d'une lentille de contact du moule dans lequel elle a été coulée et consistant à enduire ledit moule et la lentille de contact d'une solution de démoulage à base d'isopropanol.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU80877/94A AU8087794A (en) | 1993-10-28 | 1994-10-25 | Method of releasing contact lenses from the mold |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14492393A | 1993-10-28 | 1993-10-28 | |
US08/144,923 | 1993-10-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1995011789A1 true WO1995011789A1 (fr) | 1995-05-04 |
Family
ID=22510771
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1994/012144 WO1995011789A1 (fr) | 1993-10-28 | 1994-10-25 | Procede d'extraction d'une lentille de contact de son moule |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU8087794A (fr) |
WO (1) | WO1995011789A1 (fr) |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001030559A1 (fr) * | 1999-10-25 | 2001-05-03 | Hydron Limited | Procede de production de dispositifs ophtalmiques |
WO2003082367A3 (fr) * | 2002-03-28 | 2003-12-04 | Bausch & Lomb | Procede d'elimination de matieres extractibles se trouvant dans des dispositifs biomedicaux |
WO2007075558A3 (fr) * | 2005-12-29 | 2007-09-07 | Johnson & Johnson Vision Care | Procedes et systemes de liberation de lentilles optiques constituees d'hydrogel de silicone au moyen de tensioactifs |
WO2007075760A3 (fr) * | 2005-12-20 | 2007-09-07 | Johnson & Johnson Vision Care | Procedes et systemes de lixiviation et de liberation de lentilles optiques constituees d'hydrogel de silicone au moyen de solutions alcoolisees |
EP1752166A3 (fr) * | 2005-08-09 | 2007-10-03 | CooperVision Inc. | Procédé pour l'extraction/immersion des lentilles de contact et traitement des agents d'extraction |
WO2008036795A1 (fr) * | 2006-09-21 | 2008-03-27 | Novartis Ag | Procédé de démoulage de lentilles de contact |
RU2389608C2 (ru) * | 2005-12-20 | 2010-05-20 | Джонсон Энд Джонсон Вижн Кэа, Инк. | Способы и системы для выщелачивания и извлечения офтальмологических линз на основе силиконового гидрогеля спиртовыми растворами |
US7811483B2 (en) | 2006-06-01 | 2010-10-12 | Coopervision International Holding Company, Lp | Delensing of ophthalmic lenses using gas |
EP1752280A3 (fr) * | 2005-08-09 | 2010-11-17 | CooperVision International Holding Company, LP | Procédés de démoulage de lentilles et systèmes pour la fabrication de lentilles de contact content du silicone |
US7968018B2 (en) | 2007-04-18 | 2011-06-28 | Coopervision International Holding Company, Lp | Use of surfactants in extraction procedures for silicone hydrogel ophthalmic lenses |
US8313675B2 (en) | 2009-08-31 | 2012-11-20 | Coopervision International Holding Company, Lp | Demolding of ophthalmic lenses during the manufacture thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04212819A (ja) * | 1990-10-16 | 1992-08-04 | Seiko Epson Corp | プラスチックレンズの製造方法 |
-
1994
- 1994-10-25 WO PCT/US1994/012144 patent/WO1995011789A1/fr active Application Filing
- 1994-10-25 AU AU80877/94A patent/AU8087794A/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04212819A (ja) * | 1990-10-16 | 1992-08-04 | Seiko Epson Corp | プラスチックレンズの製造方法 |
Non-Patent Citations (1)
Title |
---|
DATABASE WPI Week 9237, Derwent World Patents Index; AN 92-305328, "production of plastic moulding for lenses" * |
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001030559A1 (fr) * | 1999-10-25 | 2001-05-03 | Hydron Limited | Procede de production de dispositifs ophtalmiques |
WO2003082367A3 (fr) * | 2002-03-28 | 2003-12-04 | Bausch & Lomb | Procede d'elimination de matieres extractibles se trouvant dans des dispositifs biomedicaux |
EP2345429A1 (fr) * | 2005-08-09 | 2011-07-20 | CooperVision International Holding Company, LP | Procédé pour l'extraction/immersion des lentilles de contact et traitement des agents d'extraction |
EP1752166A3 (fr) * | 2005-08-09 | 2007-10-03 | CooperVision Inc. | Procédé pour l'extraction/immersion des lentilles de contact et traitement des agents d'extraction |
US7319133B2 (en) | 2005-08-09 | 2008-01-15 | Coopervision, Inc. | Contact lens extraction/hydration systems and methods of reprocessing fluids used therein |
US9102110B2 (en) | 2005-08-09 | 2015-08-11 | Coopervision International Holding Company, Lp | Systems and methods for removing lenses from lens molds |
US7629436B2 (en) | 2005-08-09 | 2009-12-08 | CooperVision International Holding Compound, LP | Contact lens extraction/hydration systems and methods of reprocessing fluids used therein |
EP1752280A3 (fr) * | 2005-08-09 | 2010-11-17 | CooperVision International Holding Company, LP | Procédés de démoulage de lentilles et systèmes pour la fabrication de lentilles de contact content du silicone |
RU2389608C2 (ru) * | 2005-12-20 | 2010-05-20 | Джонсон Энд Джонсон Вижн Кэа, Инк. | Способы и системы для выщелачивания и извлечения офтальмологических линз на основе силиконового гидрогеля спиртовыми растворами |
WO2007075760A3 (fr) * | 2005-12-20 | 2007-09-07 | Johnson & Johnson Vision Care | Procedes et systemes de lixiviation et de liberation de lentilles optiques constituees d'hydrogel de silicone au moyen de solutions alcoolisees |
WO2007075558A3 (fr) * | 2005-12-29 | 2007-09-07 | Johnson & Johnson Vision Care | Procedes et systemes de liberation de lentilles optiques constituees d'hydrogel de silicone au moyen de tensioactifs |
US7811483B2 (en) | 2006-06-01 | 2010-10-12 | Coopervision International Holding Company, Lp | Delensing of ophthalmic lenses using gas |
US8197724B2 (en) | 2006-06-01 | 2012-06-12 | Coopervision International Holding Company, Lp | Delensing of ophthalmic lenses using gas |
WO2008036795A1 (fr) * | 2006-09-21 | 2008-03-27 | Novartis Ag | Procédé de démoulage de lentilles de contact |
US7968018B2 (en) | 2007-04-18 | 2011-06-28 | Coopervision International Holding Company, Lp | Use of surfactants in extraction procedures for silicone hydrogel ophthalmic lenses |
US8313675B2 (en) | 2009-08-31 | 2012-11-20 | Coopervision International Holding Company, Lp | Demolding of ophthalmic lenses during the manufacture thereof |
Also Published As
Publication number | Publication date |
---|---|
AU8087794A (en) | 1995-05-22 |
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