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WO1994022523A1 - Site de couplage medical a elements de renfort a fente - Google Patents

Site de couplage medical a elements de renfort a fente Download PDF

Info

Publication number
WO1994022523A1
WO1994022523A1 PCT/US1994/003234 US9403234W WO9422523A1 WO 1994022523 A1 WO1994022523 A1 WO 1994022523A1 US 9403234 W US9403234 W US 9403234W WO 9422523 A1 WO9422523 A1 WO 9422523A1
Authority
WO
WIPO (PCT)
Prior art keywords
body portion
slit
diaphragm
coupling site
medical coupling
Prior art date
Application number
PCT/US1994/003234
Other languages
English (en)
Inventor
Gordon E. Atkinson
Daniel J. Demma
David O. Werbil
Original Assignee
Vernay Laboratories, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/068,777 external-priority patent/US5295658A/en
Application filed by Vernay Laboratories, Inc. filed Critical Vernay Laboratories, Inc.
Priority to AU64161/94A priority Critical patent/AU6416194A/en
Publication of WO1994022523A1 publication Critical patent/WO1994022523A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/04—Access sites having pierceable self-sealing members
    • A61M39/045—Access sites having pierceable self-sealing members pre-slit to be pierced by blunt instrument

Definitions

  • the present invention relates to a coupling site for use in medical applications and more particularly, to a coupling site which includes a valve element and support structure for cooperation with a standard male luer lock having a male luer taper and a threaded locking collar.
  • a coupling site which includes a valve element and support structure for cooperation with a standard male luer lock having a male luer taper and a threaded locking collar.
  • needle type injection sites have the advantages of providing quick access for a fluid cannula as well as providing an access site which ensures a fluid-tight seal due to the small size of the aperture formed in the diaphragm by the needle.
  • One proposed solution for eliminating needles at coupling sites includes providing a valve member having a slit for receiving a blunt cannula therethrough wherein the slit is biased to a closed position such that a fluid-tight seal is formed at the valve member when the cannula is removed.
  • U.S. Patent No. 4,765,588 to Atkinson discloses a valve for receiving the blunt end of a syringe and includes a slit diaphragm member mounted within a tubular body wherein the diaphragm is stretched in the area of the slit and moves in close to the tubular body as a luer taper portion of the syringe is inserted.
  • the exterior wall of the body portion is dimensioned to be received within a threaded locking collar of the syringe surrounding the luer taper whereby an additional fluid-tight seal is formed with the valve.
  • One such special cannula contemplates providing a female luer connection for threadably engaging within the threaded locking collar of a male luer lock fitting on a syringe and further includes a specially configured blunt cannula having a tapered end for passing through the preslit septum of the valve.
  • the housing holding the septum may be provided with threads for engaging coupling threads located interiorly of a shield surround ⁇ ing the cannula.
  • the outer diameter of the housing is formed larger than the inner diameter of the threaded collar on the syringe in order to provide sufficient space for the septum which expands outwardly into an annular space during insertion of a cannula.
  • a medical coupling site that is usable with blunt cannula such as are provided by standard male luer lock fittings having a male luer taper surrounded by a threaded locking collar and in which the site is provided with a valve element and means for directly engaging the threads on the locking collar to form a mechanical connection.
  • Elimination of the need for a special cannula for use at the coupling site would also provide a cost advantage in that only the coupling site would need to be purchased and existing fittings could be used in conjunction with this site.
  • One problem associated with providing a coupling site for use with a standard male luer lock results from the limited space provided between the outer surface of the male luer taper and the inner surface of the threaded locking collar which makes it difficult to provide both a rigid locking surface on the outside of the fitting for engaging the locking collar and a flexible valve element of sufficient size and resilience to releasably accommodate the male luer taper.
  • the Atkinson patent described above describes a valve element which may be used with a luer fitting, but in which the outer surface of the elasto ⁇ meric valve element is received in contact with the locking collar without the inclusion of any rigid member for engaging the threads within the collar.
  • the PCT publication described above discloses an alternative approach to the same problem in that the adapter provided for attachment to a standard luer lock is provided with a locking collar which is larger than the locking collar provided on the male luer lock, thus permitting the coupling site to be constructed with an enlarged diameter to accommodate a sufficiently large septum for receiving a cannula having the desired diameter for providing sufficient flow through the site.
  • valve element which will both receive a luer taper as well as reliably reseal after the luer taper is removed.
  • prior art valves for receiving a luer taper provide a thick disk or septum, such as is disclosed in the above-noted PCT publication, wherein the disk or septum is formed with a sufficient amount of resilient material around the slit to close the slit when a cannula is not present.
  • Space must be provided in order to accommodate the distortion of material around the slit as the cannula is inserted and this space must either be provided within the fluid passage area for receiving the cannula or within the housing supporting the disk or septum, such as may be provided by an annular space directly adjacent to the outer periphery of the disk or septum.
  • the slit may be formed in a relatively thin diaphragm, such as is disclosed in the Atkinson patent, wherein sufficient space for receiving the distorted portions of the diaphragm around the slit is provided within a space defined by a tubular body portion for receiving the luer taper.
  • sufficient space must be provided around the circum ⁇ ference of any valve member in order to accommodate distortion of the resilient material forming the valve member such that little space is available for additionally accommodating a rigid member adapted to engage the threaded locking collars surrounding the male luer taper.
  • the forces provided by the material to resiliently bias the slit to a closed position are also reduced and thus may res ⁇ lt in an undesirable structure which will not positively seal the slit closed upon removal of a cannula or luer taper.
  • a coupling site which is adapted to receive cannula having a diameter at least as large as a standard male luer taper in order to avoid introducing any restriction to flow at the site with resulting reductions in the flow rate.
  • a medical fluid path coupling site which may be coupled directly to a standard male luer lock including means for forming a mechanical connection with a threaded locking collar portion of the luer lock.
  • a site including a valve in which a slit for receiving a male luer taper portion of the male luer lock is positively biased to a closed position to prevent leakage through the valve when the male luer taper is removed.
  • the present invention provides a coupling site for use in medical fluid flow applications wherein the coupling site is adapted for use with a standard male luer lock having a male luer taper and a threaded locking collar.
  • the medical coupling site of the present invention is preferably configured for use with a male luer lock constructed according to ANSI and ISO standards such that the coupling site of the present invention is adapted for immediate use in fluid flow paths currently in use throughout the world without the necessity of any adapter couplings being provided between the coupling site and existing standard luer fittings.
  • the medical coupling site of the present invention includes a support base defining a longitudinal axis for the coupling site, and a retainer supported on the base.
  • An elastomeric valve element is located within the retainer and includes a substantially tubular body portion having first and second ends and a diaphragm member extending across the first end of the body portion.
  • Lug means are provided extending radially outwardly from the retainer for engaging threads on the threaded locking collar of the male luer lock.
  • the lug means are preferably located at an end of the retainer adjacent to the diaphragm member of the valve element.
  • the body portion of the valve element includes an outer wall in contact with an inner wall of the retainer.
  • an inner wall of the valve element body portion defines a tubular passage for receiving the male luer taper portion of the male luer lock.
  • the diaphragm member includes means defining a slit extending diametrically across the diaphragm member, and biasing means extend inwardly from the inner wall of the body portion toward the slit for biasing the slit to a closed position.
  • the biasing means preferably include discrete members, such as ribs, extending radially inwardly in a direction from the second end of the body portion toward the first end thereof.
  • the biasing means increase the effectiveness of the diaphragm to quickly close the slit when a cannula or luer taper is not present while also providing space for the deformation of the diaphragm member during insertion of a cannula or luer taper.
  • the biasing means ensure that the slit is positively sealed when a cannula is not present.
  • the retainer is formed as a thin structure relative to the body portion.
  • a thickness of the body portion is greater than a thickness of the retainer, measured in the same direction, at a location adjacent to the lug means.
  • the retainer is preferably formed from thin metal and the lug means are formed as first and second protrusions formed in the metal on opposite sides of the retainer.
  • the retainer extends from a location adjacent to the first end of the body portion to a location adjacent to the support base and the body portion of the valve element extends along the retainer and is positioned in contact with the support base such that fluids flowing through the coupling site will not contact the retainer.
  • the body portion is preferably sandwiched between the retainer and the support base at the second end of the body portion whereby the valve element is held in place relative to the support base.
  • the diaphragm of the valve element is formed having a concave outer surface and a convex inner surface wherein the concave surface has a peripheral edge lying in a plane defined by an annular end surface of the body portion. Further, the concave surface is relatively shallow such that it may be easily sterilized prior to insertion of a cannula.
  • a pair of stiffening ribs extend radially inwardly from the inner wall to points adjacent to the ends of the slit.
  • the stiffening ribs ensure that the diaphragm does not tear from the ends of the slit outwardly toward the inner wall and further ensure that the adjoining surfaces defining the slit move into alignment with each other when the slit is closed.
  • FIG. 1 is a perspective view of the medical coupling site of the present invention
  • Fig. 2 is a cross-sectional view of the coupling site taken along line 2—2 in Fig. 1, and additionally showing a male luer lock fitting for connection to the coupling site;
  • FIG. 3 is a view similar to Fig. 2 in which the male luer lock fitting is shown inserted into the coupling site prior to threaded engagement of the male luer lock fitting with the coupling site;
  • Fig. 4 is a cross-sectional view of the coupling site taken along line 4--4 in Fig. 1;
  • Fig. 5 is a cross-sectional view taken along line 5—5 in Fig. 2;
  • Fig. 6 is a perspective view of a second embodiment of the medical coupling device of the present invention.
  • Fig. 7 is a cross-sectional view taken along line 7—7 in Fig. 6, and additionally showing a male luer lock fitting for connection to the coupling site;
  • Fig. 8 is a cross-sectional view similar to
  • FIG. 7 in which the male luer lock fitting is shown inserted into the coupling site prior to threaded engagement of the male luer lock with the coupling site;
  • Fig. 9 is a cross-sectional view similar to that shown in Fig. 2 illustrating an alternative configuration for the valve element;
  • Fig. 10 is a cross-sectional view taken along line 10—10 in Fig. 9;
  • Fig. 11 is a cross-sectional view taken along line 11—11 in Fig. 9;
  • Fig. 12 is a cross-sectional view similar to that shown in Fig. 2 illustrating a further embodiment of the present invention;
  • Fig. 13 is a cross-sectional view of an alternative embodiment for the valve element of the present invention taken along line 13—13 in Fig. 15;
  • Fig. 14 is a cross-sectional view of the valve element of Fig. 13 taken along line 14--14 in Fig. 15;
  • Fig. 15 is a top plan view of the valve element of Fig. 13;
  • Fig. 16 is a bottom plan view of the valve element of Fig. 13.
  • the coupling site 10 generally includes a support base 12, a retainer 14 supported on the support base and a valve element 16 located within the retainer.
  • the support base 12 is formed from a plastic material
  • the retainer 14 is formed from a metal material such as coated aluminum
  • the valve element 16 is formed of an elastomeric material such as an elastomer which conforms to standard medical specifications.
  • the support base 12 preferably includes a tubular luer taper portion 18 defining a longitudinal axis 20 of the coupling site 10.
  • the luer taper portion 18 is surrounded by a threaded locking collar 22 such that the coupling site 10 may be attached to a standard female luer fitting.
  • an outwardly extending flange portion 24 is attached to an inner end of the luer taper portion 18 extending from an end wall 26 of the collar 22.
  • the valve member 16 includes a tubular body portion 28 extending substantially parallel to the longitudinal axis 20 and defining a first end 30 and a second end 32 wherein the second end 32 is in contact with the support base 12 adjacent to the end wall 26.
  • the valve element 16 further includes a thin flexible diaphragm 34 extending across the first end 30 of the body portion 16.
  • the diaphragm 34 includes means defining a slit 36 extending diametrically across the diaphragm 34.
  • the diaphragm 34 defines opposing first and second sides 38, 40 wherein the first side 38 is formed as a concave surface and the second side 40 is formed as a convex surface.
  • the concave first surface 38 includes a peripheral edge lying in a plane defined by an annular end surface 42 of the body portion 16. It should be noted that the first surface 38 is provided with a relatively shallow curvature such that the first surface 38 is easily cleaned by wiping of the surface.
  • the second surface 40 is shown having a substantially cylindrical curvature, it should be noted that this surface may also be formed having a spherical or dome-shaped curvature.
  • the valve element 16 is further provided with biasing means which are preferably in the form of first and second ribs 44, 46 extending radially inwardly from an inner wall 48 of the body portion 16 toward the slit 36 in a direction from the second end 32 toward the first end 30.
  • the rib members 44, 46 are oriented such that they intersect and extend parallel to a plane which intersects the longitudinal axis 20 and extends perpendicular to the slit 36.
  • each of the rib members 44, 46 define a width dimension in a direction parallel to the slit 36 which is less than an interior diameter defined by the inner wall 48 of the valve body 16.
  • the rib members 44, 46 have a dimension in a direction parallel to the longitudinal axis 20 which decreases in a direction from the inner wall 48 toward the slit 36.
  • the rib members 44, 46 reinforce the diaphragm 34 and act to bias the slit 36 to a closed position. Further, by providing rib members 44, 46 which have a width dimension less than the inner diameter of the body portion 16, the space surrounding the rib members 44, 46 is available to accommodate elastomeric material of the diaphragm 34 and body portion 28 as the valve element 16 is distorted during insertion of a male luer taper 50 (see Fig. 2) .
  • the retainer 14 is formed as a tubular sleeve defined by an elongated body 52 having a first end 54 adjacent to the first end 30 of the valve element 16 and a second end 56 adjacent to the second end 32 of the valve element 16.
  • the first end 54 of the retainer 14 is turned inwardly into the first end of the valve element 16 and is preferably folded over to form a double thickness portion. This portion forms a reduced area for slightly compressing the valve element 16 in the area ' around the diaphragm 34 to thereby form a seal preventing fluids from passing between the valve element 16 and the retainer 14.
  • the second end 56 is preferably crimped inwardly toward a gap formed between the flange portion 24 and the end wall 26 to thereby hold the second end 32 of the valve element 16 under the flange portion 24 such that the valve element 16 is firmly held in place on the support base 12.
  • valve body portion 28 extends substantially along the length of the retainer 14 and isolates the retainer 14 from fluids flowing through the coupling site > as well as forms a direct fluid path through the site 10 to avoid the formation of crevices or pockets which may retain fluids and hinder flushing of the site between administration of different medicines.
  • the inner surface of the elongated body 52 preferably defines a diameter which is slightly smaller than the outer diameter of the body portion 28 prior to mounting in the coupling site 10.
  • the retainer 14 further includes a pair of lugs 58, 60 extending radially outwardly from the outer surface of the retainer body 52.
  • the retainer 14 is preferably formed from thin material such as coated aluminum, which may be conveniently stamped to a desired shape.
  • the lugs 58, 60 may be formed as stamped protrusions in the body 52.
  • the lugs 58, 60 are configured to engage the double helix threads formed on the interior of a threaded locking collar 62 (see Fig. 2) for a standard male luer lock.
  • the lugs 58, 60 may be formed extending at a slight angle relative to a plane extending perpendicular to the longitudinal axis 20.
  • the lugs may be formed having an alternative configuration, such as a configuration defining threads extending around the entire circumference of the retainer body 52 and that other means of forming the thin metal retainer, such as machining, may be applied.
  • the lugs 58, 60 are preferably located adjacent to the first end 54 of the retainer 14 and the thickness of the retainer body portion 52 in at least the area adjacent to the lugs has a thickness, as measured in a direction perpendicular to the longitudinal axis 20, which is less than the thickness of the valve element body portion 28.
  • the relationship between the thickness of the retainer 14 and the valve element 16 is important since only a limited amount of space is available between a standard male luer taper 50 and the surrounded locking collar 62.
  • a standard male luer lock 64 is illustrated and may be in the form of a standard syringe end including a male luer taper 50 and a threaded locking collar 62.
  • the male luer taper 50 has an outer diameter of approximately 3.9 mm to 4.0 mm and the threaded locking collar 62 has a minimum inner diameter, as defined by the threaded portion of approximately 7.0 mm to 7.2 mm.
  • the male luer taper is formed tapering inwardly at an angle of 6".
  • the retainer 14 of the coupling site 10 is formed having a maximum outer diameter for the retainer body 52 of approximately 7.0 mm, and the inner wall 48 of the valve element 16 defines a minimum diameter of 4 mm.
  • the configuration of the present coupling site 10 results in a site which is particularly adapted to be received between the male luer tip 50 and the locking collar 62 with the outer surface of the site 10 forming a positive mechanical connection with the threads of the collar 62 and with the interior of the valve body 28 providing sufficient clearance for the male luer taper 50 to easily slide into the coupling site 10.
  • end surface 65 of the luer taper 18 may serve as a convenient stop surface for engaging the end of the luer taper 50 to define a positive lock position between the male luer lock 64 and the coupling site 10.
  • the male luer taper 50 causes the diaphragm 34 to be stretched and pushed into a distorted position adjacent to the inner wall 48, with an accompanying distortion of the ribs 44, 46.
  • the coupling site 10 of the present invention incorporates a flexible diaphragm member 34 having a slit 36 wherein the slit is biased to a closed position through forces exerted on the diaphragm member by a supporting tubular body portion 28 forming a passage for receiving the male luer taper.
  • a diaphragm member 34 for forming the seal on the site end results in a highly resilient opening offering reduced resistance to forces pushing the male luer taper 50 or other cannula into the coupling site 10 while also providing a reliable closure element when the male luer taper 50 is removed from the site 10.
  • the present coupling site 10 may also easily be used with a needle in that a needle may be inserted through the diaphragm 34 in the region surrounding the slit 36 if it should be necessary to infuse or withdraw fluids through a needle at the injection site.
  • a second embodiment of the present invention is shown and is designated generally as 10'.
  • elements in the second embodiment corresponding to elements in the first embodiment are labeled with the same reference numeral primed.
  • the embodiment of Figs. 6-8 differs from the previous embodiment in that the area surrounded by the flange portion 24' includes an enlarged passage defining a luer slip 66' which is adapted to receive the end of a standard male luer taper 50'.
  • the area of the second end 32' of the body portion 16' and the second end 56' of the retainer 14' are formed with an enlarged diameter, as compared to the previous embodiment, in order to accommodate the enlarged luer slip area 66'.
  • the portion of the valve body 28' and the retainer body 52' adjacent to the lugs 58', 60* is formed with the same diameter as in the previous embodiment such that the coupling site 10' will cooperate with a standard male luer lock 64' in the same manner as in the previous embodiment.
  • the tip of the luer taper 50' will pass into the luer slip 66' whereby an additional seal is formed between the exterior of the luer taper 50' and the interior of the luer slip 66'.
  • the contact between the luer taper 50' and luer slip 66' defines a positive lock position between the luer lock 64' and the coupling site 10'.
  • Figs. 6-8 does not affect the advantages afforded by passage of the retainer 14' and valve element 16' in between the luer taper 50* and the locking collar 62' to form a sealed connection wherein the standard luer lock 64' is mechanically locked onto the coupling site 10' .
  • Figs. 9-11 show an alternative to the first embodiment in which an alternative valve element 16*' is shown and in which the elements for the retainer 14 and the support base 12 remain unchanged and are identified with the same reference numerals as in the first embodiment.
  • the valve element 16'' of the present embodiment differs from the valve element 16 of the first embodiment in that a different rib structure is provided for biasing the slit 36'' to a closed position. Specifically, a pair of rib portions 44'', 45'' and 46"', 47'' are provided on opposing sides of the slit 36''. Each pair of rib members 44'', 45'' and 46'', 47*' is separated by a space 68'', 70'', respectively.
  • the rib members 44''-47' J operate in the same manner as the ribs 44, 46 of the first embodiment to reinforce the diaphragm 34'' and bias the slit 36'' to a closed position.
  • the spaces 68'', 70'' provide an area for the material of the valve element 16'' to deform into when a male luer taper is inserted into the coupling site.
  • the rib members may be provided in order to bias the valve diaphragm to a closed position.
  • the curved surface of the ribs 44, 46 extending from the inner wall 48 of the valve element 16 to the slit 36 may be formed as a straight inwardly angled surface or may be provided with some other shape.
  • the design of the diaphragm 34 and the reinforcing rib members 44, 46 for biasing the slit to a closed position may be altered to provide a predetermined resistance to back flow through the valve element 16.
  • the valve element 16 may be designed to release fluid from the slit 36 at a predetermined pressure in order to avoid excessive pressure from being applied into a patient at an infusion site.
  • valve 34 may be formed as a planar element having opposing first and second sides which are substantially flat. By providing an outwardly facing planar surface, the valve of the present invention would be particularly easy to clean by wiping of the surface.
  • Fig. 12 shows a further alternative embodiment to the first embodiment in which elements of the further embodiment corresponding to elements in the first embodiment are labeled with the same reference numerals increased by 100.
  • the retainer 114 is a formed thin element of any relatively rigid material such as metal or plastic.
  • the second end 156 of the retainer includes an enlarged end surface 155 engaging a flange portion 157 of the valve element 116.
  • the flange portion 157 is located with a groove defined between an inner end of the luer taper portion 118 and a lip 159 extending from the support base 112.
  • the lip 159 firmly engages the enlarged second end 156 of the retainer 114 in frictional contact to positively maintain the elements of the coupling site 110 in position relative to each other.
  • the coupling site 110 operates in a manner identical to that of the previous embodiments and differs only in the manner of forming the retainer 114 and in the structure for mounting the retainer 114 and the valve element 116 to the support base 112.
  • the retainer of the present invention may also be formed from a plastic material provided the plastic has sufficient rigidity to resist deformation during assembly and use of the coupling site.
  • Figs. 13-16 illustrate a further embodiment of the invention in which elements corresponding to elements in the first embodiment are labeled with the same reference numerals increased by 200.
  • the present embodiment is directed to an improved valve element 216 having stiffening ribs 270, 272 extending radially inwardly from opposing sides of the inner wall 248 to locations adjacent to respective ends of the slit 236.
  • the stiffening ribs 270, 272 are formed integrally with the elastomeric material of the diaphragm 234, and extend axially from the second or inner surface 240 of the diaphragm 234 toward the second end 232 of the valve element 216.
  • the inner face 240 of the diaphragm 234 of the present embodiment is formed having a convex dome shape which is substantially the same shape as the first or outer concave surface 238.
  • the valve element 216 is provided with radially inwardly extending biasing ribs 244 and 246 for biasing the slit 236 closed.
  • the biasing ribs 244, 246 lie within and extend parallel to a first plane 274 which contains the longitudinal axis 220 and which is perpendicular to the slit 236, and the stiffening ribs 270, 272 extend parallel to a second plane 276 which is perpendicular to the first plane 274 and which also contains the longitudinal axis 220.
  • the stiffening ribs 270, 272 have a width dimension in a direction perpendicular to the slit 236 which is less than the interior diameter of the body portion 228.
  • the stiffening ribs 270, 272 act to prevent the diaphragm 234 from tearing adjacent to the ends of the slit 236, such that the slit 236 is prevented from propagating to the inner wall 248. In addition, the stiffening ribs 270, 272 ensure that the adjoining surfaces of the diaphragm 234 defining the slit 236 will be maintained in alignment with each other when they move together to close the slit 236.
  • stiffening ribs 270, 272 act to stiffen the diaphragm 234 adjacent to the ends of the slit 236, and are formed of the same elastomeric material as the diaphragm 234 and the body portion 228 such that they are adapted to be resiliently displaced when a male luer is inserted through the slit 236 to facilitate easy insertion of the luer.
  • valve element 216 of the present embodiment is adapted to be positioned within a retainer having lugs for threadably engaging an internally threaded collar of a male luer lock such that the luer taper may be held in a positive locked position relative to the valve element 216.
  • the medical coupling site of the present invention overcomes the disadvantages associated with prior art sites.
  • the present medical coupling site is provided with a wall structure having a sufficiently thin dimension to pass within the space defined between a standard male luer taper and a locking collar for a standard male luer lock fitting.
  • the outer surface of the coupling site is provided with rigidly supported lugs for engaging the double helix threads of the threaded locking collar for a male luer lock whereby the coupling site is held in fixed mechanical engagement with the male luer lock.
  • the present invention also has an advantage over prior art sites requiring a reduced diameter cannula for insertion through a valve element in that the present invention permits a standard luer taper to be inserted through the valve into the coupling site and the interior diameter of the coupling site is at least as large as the interior diameter of a standard luer taper.
  • the coupling site of the present invention does not impose any restrictions to flow resulting from reductions of diameter within the site.
  • a further advantage of the present invention results from providing biasing means in the form of ribs for controlling the location of the diaphragm and thereby maintaining the slit in a closed position.
  • the diaphragm of the present invention does not require excessive forces directed inwardly toward the slit in order to maintain the slit in a closed position, and as a result thereof the ease of insertion of a luer taper into the valve is greatly enhanced.
  • a thin rigid retainer in combination with a tubular valve- element having a diaphragm extending across an end thereof provides a critical dual function of both providing a mounting structure for the radially extending lugs and also acting as a reinforcing structure to rigidly support the valve element and thereby ensure closure of the slit, as well as prevent inadvertent opening of the slit resulting from side forces applied to the coupling site at the location of the valve element.
  • Other advantages associated with the present invention include the simplicity with which the medical coupling site may be incorporated into existing medical fluid systems without change over of equipment or the use of adapters to incorporate non-standard fittings.
  • the present invention is particularly adapted to be used with standard male luer locks, it may also be used with other cannula or may be accessed with a conventional steel needle.
  • the coupling site further provides for a positive feedback of a locked connection such that medical personnel will be able to quickly connect male luer lock fittings to the site.
  • the resiliency of the valve element diaphragm enables the present coupling site to be used for multiple insertions and with extended indwell times while maintaining its capability to form a fluid- tight seal at the slit upon removal of a luer taper or cannula.
  • the design of the coupling site with the valve element extending from a point adjacent to the first end of the sleeve to a point in contact with the support base further ensures that crevices for containing pockets of fluid are avoided such that flushing of the valve in between administration of medicines is facilitated.

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un site de couplage médical comprenant un élément à valve élastomère (210) défini par un corps tubulaire (228) et un diaphragme (234) s'étendant diamétralement depuis une extrémité du corps. Le diaphragme présente une fente (236) comportant des extrémités opposées se terminant à une certaine distance d'une paroi interne du corps. Des première et deuxième nervures raidisseuses élastomères (270, 272) font partie intégrante du diaphragme et de la zone du corps adjacente aux extrémités de la fente, lesdites nervures raidisseuses empêchant le diaphragme de se déchirer à proximité des extrémités de la fente et facilitant l'alignement des surfaces contiguës du diaphragme définissant la fente.
PCT/US1994/003234 1993-04-05 1994-03-24 Site de couplage medical a elements de renfort a fente WO1994022523A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU64161/94A AU6416194A (en) 1993-04-05 1994-03-24 Medical coupling site including slit reinforcing members

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US4252593A 1993-04-05 1993-04-05
US042,525 1993-04-05
US068,777 1993-06-01
US08/068,777 US5295658A (en) 1987-04-27 1993-06-01 Medical coupling site including slit reinforcing members

Publications (1)

Publication Number Publication Date
WO1994022523A1 true WO1994022523A1 (fr) 1994-10-13

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Application Number Title Priority Date Filing Date
PCT/US1994/003234 WO1994022523A1 (fr) 1993-04-05 1994-03-24 Site de couplage medical a elements de renfort a fente

Country Status (2)

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AU (1) AU6416194A (fr)
WO (1) WO1994022523A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9278206B2 (en) 2009-03-25 2016-03-08 Icu Medical, Inc. Medical connectors and methods of use
US9750926B2 (en) 2010-05-17 2017-09-05 Icu Medical, Inc. Medical connectors and methods of use
US9884176B2 (en) 2004-11-05 2018-02-06 Icu Medical, Inc. Medical connector
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US10722698B2 (en) 2004-11-05 2020-07-28 Icu Medical, Inc. Medical connector
US10799692B2 (en) 2009-03-25 2020-10-13 Icu Medical, Inc. Medical connectors and methods of use
US12059545B2 (en) 2009-03-25 2024-08-13 Icu Medical, Inc. Medical connector with elongated portion within seal collar
US9278206B2 (en) 2009-03-25 2016-03-08 Icu Medical, Inc. Medical connectors and methods of use
US10391293B2 (en) 2009-03-25 2019-08-27 Icu Medical, Inc. Medical connectors and methods of use
US12285584B2 (en) 2009-03-25 2025-04-29 Icu Medical, Inc. Medical connector with elongated portion within seal collar
US11986618B1 (en) 2009-03-25 2024-05-21 Icu Medical, Inc. Medical connector having elongated portion within seal collar
US12102786B2 (en) 2009-03-25 2024-10-01 Icu Medical, Inc. Medical connector with elongated portion within seal collar
US10086188B2 (en) 2009-03-25 2018-10-02 Icu Medical, Inc. Medical connectors and methods of use
US11376411B2 (en) 2009-03-25 2022-07-05 Icu Medical, Inc. Medical connectors and methods of use
US11931539B2 (en) 2009-03-25 2024-03-19 Icu Medical, Inc. Medical connectors and methods of use
US9440060B2 (en) 2009-03-25 2016-09-13 Icu Medical, Inc. Medical connectors and methods of use
US11896795B2 (en) 2009-03-25 2024-02-13 Icu Medical, Inc Medical connector having elongated portion within closely conforming seal collar
USD1003434S1 (en) 2010-03-23 2023-10-31 Icu Medical, Inc. Medical connector seal
USD1029246S1 (en) 2010-03-23 2024-05-28 Icu Medical, Inc. Medical connector seal
US10195413B2 (en) 2010-05-17 2019-02-05 Icu Medical, Inc. Medical connectors and methods of use
US11071852B2 (en) 2010-05-17 2021-07-27 Icu Medical, Inc. Medical connectors and methods of use
US9750926B2 (en) 2010-05-17 2017-09-05 Icu Medical, Inc. Medical connectors and methods of use
US11364372B2 (en) 2013-12-11 2022-06-21 Icu Medical, Inc. Check valve

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