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WO1994020621A3 - Proteinaceous particles containing retroviral element - Google Patents

Proteinaceous particles containing retroviral element Download PDF

Info

Publication number
WO1994020621A3
WO1994020621A3 PCT/GB1994/000281 GB9400281W WO9420621A3 WO 1994020621 A3 WO1994020621 A3 WO 1994020621A3 GB 9400281 W GB9400281 W GB 9400281W WO 9420621 A3 WO9420621 A3 WO 9420621A3
Authority
WO
WIPO (PCT)
Prior art keywords
particles containing
proteinaceous particles
containing retroviral
construct
retroviral element
Prior art date
Application number
PCT/GB1994/000281
Other languages
French (fr)
Other versions
WO1994020621A2 (en
Inventor
Lloyd George Czaplewski
Original Assignee
British Bio Technology
Lloyd George Czaplewski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Bio Technology, Lloyd George Czaplewski filed Critical British Bio Technology
Priority to AU60063/94A priority Critical patent/AU6006394A/en
Publication of WO1994020621A2 publication Critical patent/WO1994020621A2/en
Publication of WO1994020621A3 publication Critical patent/WO1994020621A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/17011—Spumavirus, e.g. chimpanzee foamy virus
    • C12N2740/17022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

A DNA construct comprising (a) a single promoter; (b) a gag-derived sequence from a complex retrovirus; (c) a rev-like element; (d) an RRE-like element; and (e) donor and acceptor elements; wherein (i) elements (a) to (e) are arranged in such a fashion that in the construct that the promoter is capable of driving expression of both the gag-derived sequence and, by virtue of the donor and acceptor elements, the rev-like element; (ii) the construct does not contain a functional env gene.
PCT/GB1994/000281 1993-03-01 1994-02-11 Proteinaceous particles containing retroviral element WO1994020621A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU60063/94A AU6006394A (en) 1993-03-01 1994-02-11 Proteinaceous particles containing retroviral element

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939304239A GB9304239D0 (en) 1993-03-01 1993-03-01 Viral particles
GB9304239.8 1993-03-01

Publications (2)

Publication Number Publication Date
WO1994020621A2 WO1994020621A2 (en) 1994-09-15
WO1994020621A3 true WO1994020621A3 (en) 1994-10-13

Family

ID=10731331

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1994/000281 WO1994020621A2 (en) 1993-03-01 1994-02-11 Proteinaceous particles containing retroviral element

Country Status (3)

Country Link
AU (1) AU6006394A (en)
GB (1) GB9304239D0 (en)
WO (1) WO1994020621A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001633A (en) * 1995-06-02 1999-12-14 Wakunaga Seiyaku Kabushiki Kaisha Cells producing recombinant retrovirus
DE19617851A1 (en) 1996-05-03 1997-11-13 Hoechst Ag Nucleic acid constructs with genes coding for transport signals
GB9621091D0 (en) 1996-10-09 1996-11-27 Fondation Pour Le Perfectionem Attenuated microorganisms strains and their uses
WO2000078987A1 (en) * 1999-06-22 2000-12-28 Dnavec Research Inc. Vector for expressing two foreign genes
US7476517B2 (en) 1999-06-30 2009-01-13 Evotec Ag Virus like particles, their preparation and their use preferably in pharmaceutical screening and functional genomics
DK1187928T3 (en) * 1999-06-30 2007-10-08 Evotec Ag Virus-like particles, preparation and use in screening as well as in functional genomics
US20040014033A1 (en) 1999-06-30 2004-01-22 Evotec Biosystems Ag, A Corporation Of Germany Virus like particles, their preparation and their use preferably in pharmaceutical screening and functional genomics
GB0216081D0 (en) * 2002-07-11 2002-08-21 Imp College Innovations Ltd Methods of making biological materials and uses thereof
US20110142880A1 (en) * 2008-03-28 2011-06-16 Franck Yann Lemiale Lentivirus-based immunogenic vectors
CA3143327A1 (en) * 2019-06-13 2020-12-17 J. Keith Joung Engineered human-endogenous virus-like particles and methods of use thereof for delivery to cells

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991007425A1 (en) * 1989-11-20 1991-05-30 Oncogen Limited Partnership Non-replicating recombinant-made retroviral particles used as antiviral agents and immunogens

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991007425A1 (en) * 1989-11-20 1991-05-30 Oncogen Limited Partnership Non-replicating recombinant-made retroviral particles used as antiviral agents and immunogens

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
L. LUO ET AL.;: "Chimeric gag-V3 virus-like particles of human immunodeficiency virus induce virus-neutralizing antibodies", PROC. NATL. ACAD. SCI. USA, vol. 89, 1992, pages 10527 - 10531 *
S.K. VERNON ET AL.;: "Ultrastructural characterization of human immunodeficiency virus type 1 Gag-containing particles assembled in a recombinant adenovirus vector system", J. GEN. VIROL., vol. 72, 1991, pages 1243 - 1251 *

Also Published As

Publication number Publication date
AU6006394A (en) 1994-09-26
GB9304239D0 (en) 1993-04-21
WO1994020621A2 (en) 1994-09-15

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