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WO1994011518A3 - Procedes de conversion de groupes sanguins a, ab et b en groupe sanguin o - Google Patents

Procedes de conversion de groupes sanguins a, ab et b en groupe sanguin o Download PDF

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Publication number
WO1994011518A3
WO1994011518A3 PCT/US1993/010794 US9310794W WO9411518A3 WO 1994011518 A3 WO1994011518 A3 WO 1994011518A3 US 9310794 W US9310794 W US 9310794W WO 9411518 A3 WO9411518 A3 WO 9411518A3
Authority
WO
WIPO (PCT)
Prior art keywords
acetylgalactosaminidase
blood
converting
methods
types
Prior art date
Application number
PCT/US1993/010794
Other languages
English (en)
Other versions
WO1994011518A2 (fr
Inventor
Randy M Berka
Original Assignee
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor Int filed Critical Genencor Int
Priority to JP6512285A priority Critical patent/JPH08503137A/ja
Priority to EP94901346A priority patent/EP0668920A1/fr
Publication of WO1994011518A2 publication Critical patent/WO1994011518A2/fr
Publication of WO1994011518A3 publication Critical patent/WO1994011518A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01049—Alpha-N-acetylgalactosaminidase (3.2.1.49)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne un procédé de production d'α-N-acétylgalactosaminidase consistant à exprimer une séquence d'ADN dérivée du placenta humain, à coder une α-N-acétylgalactosaminidase dans un microorganisme hôte recombiné transformé à l'aide d'un vecteur d'expression contenant une séquence d'ADN, et à isoler des transformants présentant une expression de l'α-N-acétylgalactosaminidase. Ensuite, on met en culture les transformants isolés et on purifie l'α-N-acétylgalactosaminidase à partir des milieux de culture. On utilise l'α-N-acétylgalactosaminidase produite par recombinaison pour convertir des groupes sanguins A, B et AB en groupe sanguin O.
PCT/US1993/010794 1992-11-18 1993-11-08 Procedes de conversion de groupes sanguins a, ab et b en groupe sanguin o WO1994011518A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP6512285A JPH08503137A (ja) 1992-11-18 1993-11-08 Ａ，ａｂ及びｂ型血液をｏ型血液に変換するための方法
EP94901346A EP0668920A1 (fr) 1992-11-18 1993-11-08 Procedes de conversion de groupes sanguins a, ab et b en groupe sanguin o

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97794592A 1992-11-18 1992-11-18
US07/977,945 1992-11-18

Publications (2)

Publication Number Publication Date
WO1994011518A2 WO1994011518A2 (fr) 1994-05-26
WO1994011518A3 true WO1994011518A3 (fr) 1994-11-10

Family

ID=25525671

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1993/010794 WO1994011518A2 (fr) 1992-11-18 1993-11-08 Procedes de conversion de groupes sanguins a, ab et b en groupe sanguin o

Country Status (4)

Country Link
EP (1) EP0668920A1 (fr)
JP (1) JPH08503137A (fr)
CA (1) CA2149641A1 (fr)
WO (1) WO1994011518A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994023070A1 (fr) * 1993-03-26 1994-10-13 New York Blood Center, Inc. α-N-ACETYLGALACTOSAMINIDASE RECOMBINEE ET ADNc CODANT CETTE ENZYME
WO2019131505A1 (fr) * 2017-12-26 2019-07-04 国立大学法人徳島大学 Méthode d'introduction d'une protéine dans des cellules fongiques, et produit associé
US12103222B2 (en) 2018-12-21 2024-10-01 The Curators Of The University Of Missouri Methods and systems for drawn fused filament fabrication printing

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992007936A1 (fr) * 1990-10-24 1992-05-14 The Mount Sinai School Of Medicine Of The City University Of New York Clonage et expression de l'alpha-n-acetylgalactosaminidase biologiquement active

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992007936A1 (fr) * 1990-10-24 1992-05-14 The Mount Sinai School Of Medicine Of The City University Of New York Clonage et expression de l'alpha-n-acetylgalactosaminidase biologiquement active

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
WANG A. ET AL.: "Human alpha-N-acetylgalactosaminidase-molecular cloning, nucleotide sequence, and expression of a full-length cDNA", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 265, no. 35, December 1990 (1990-12-01), BALTIMORE, MD US, pages 21859 - 21866, XP002256779 *
YAMAUCHI TOYOAKI ET AL.: "Molecular cloning of two species of cDNAs for human alph-N-acetylgalactosaminidase and expression in mammalian cells", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 170, no. 1, 16 July 1990 (1990-07-16), DULUTH, MINNESOTA US, pages 231 - 237, XP001312681 *

Also Published As

Publication number Publication date
CA2149641A1 (fr) 1994-05-26
WO1994011518A2 (fr) 1994-05-26
EP0668920A1 (fr) 1995-08-30
JPH08503137A (ja) 1996-04-09

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