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WO1994001749A3 - Appareil et procedes de controle des valeurs de l'hematocrite du sang - Google Patents

Appareil et procedes de controle des valeurs de l'hematocrite du sang Download PDF

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Publication number
WO1994001749A3
WO1994001749A3 PCT/US1993/006057 US9306057W WO9401749A3 WO 1994001749 A3 WO1994001749 A3 WO 1994001749A3 US 9306057 W US9306057 W US 9306057W WO 9401749 A3 WO9401749 A3 WO 9401749A3
Authority
WO
WIPO (PCT)
Prior art keywords
light
blood
amount
hematocrit
detecting devices
Prior art date
Application number
PCT/US1993/006057
Other languages
English (en)
Other versions
WO1994001749A2 (fr
WO1994001749B1 (fr
Inventor
David L Maynard
Original Assignee
Advanced Haemotechnologies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Haemotechnologies filed Critical Advanced Haemotechnologies
Publication of WO1994001749A2 publication Critical patent/WO1994001749A2/fr
Publication of WO1994001749A3 publication Critical patent/WO1994001749A3/fr
Publication of WO1994001749B1 publication Critical patent/WO1994001749B1/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3306—Optical measuring means
    • A61M2205/331—Optical measuring means used as turbidity change detectors, e.g. for priming-blood or plasma-hemoglubine-interface detection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3306—Optical measuring means
    • A61M2205/3313—Optical measuring means used specific wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J1/00—Photometry, e.g. photographic exposure meter
    • G01J1/10—Photometry, e.g. photographic exposure meter by comparison with reference light or electric value provisionally void
    • G01J1/16—Photometry, e.g. photographic exposure meter by comparison with reference light or electric value provisionally void using electric radiation detectors
    • G01J1/1626—Arrangements with two photodetectors, the signals of which are compared
    • G01J2001/1647—Arrangements with two photodetectors, the signals of which are compared one signal maintained constant
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/05—Investigating sedimentation of particle suspensions in blood
    • G01N2015/055—Investigating sedimentation of particle suspensions in blood for hematocrite determination
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1738—Optionally different kinds of measurements; Method being valid for different kinds of measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N2021/4704—Angular selective
    • G01N2021/4709—Backscatter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's
    • G01N2201/0621—Supply
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/066—Modifiable path; multiple paths in one sample
    • G01N2201/0662—Comparing measurements on two or more paths in one sample

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne un appareil et des procédés de mesure de la valeur d'hématocrite du sang. Dans un mode préféré de réalisation, un dispositif à luminescence (14) qui émet une certaine quantité de lumière dans un échantillon de sang (12) est prévu. Cette lumière traverse l'échantillon de sang en direction de deux dispositifs de détection de lumière (18, 20) positionnés par rapport au dispositif à luminescence de telle sorte que la lumière atteigne un dispositif de détection de lumière plutôt que l'autre. La quantité de lumière détectée par un des dispositifs de détection de lumière (18, 20) est régulée de façon que la quantité de lumière détectée soit constante. La quantité de lumière détectée par le dispositif de détection de lumière non régulée est une représentation linéaire de l'hématocrite de l'échantillon de sang. Le capteur d'hématocrite peut être utilisé pour réguler les paramètres de fonctionnement d'un système d'autotransfusion afin de maintenir l'hématocrite du sang dans une plage de valeurs prédéterminée.
PCT/US1993/006057 1992-06-30 1993-06-24 Appareil et procedes de controle des valeurs de l'hematocrite du sang WO1994001749A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/906,926 US5385539A (en) 1992-06-30 1992-06-30 Apparatus for monitoring hematocrit levels of blood
US07/906,926 1992-06-30

Publications (3)

Publication Number Publication Date
WO1994001749A2 WO1994001749A2 (fr) 1994-01-20
WO1994001749A3 true WO1994001749A3 (fr) 1994-04-14
WO1994001749B1 WO1994001749B1 (fr) 1994-06-09

Family

ID=25423233

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1993/006057 WO1994001749A2 (fr) 1992-06-30 1993-06-24 Appareil et procedes de controle des valeurs de l'hematocrite du sang

Country Status (2)

Country Link
US (1) US5385539A (fr)
WO (1) WO1994001749A2 (fr)

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Publication number Publication date
WO1994001749A2 (fr) 1994-01-20
US5385539A (en) 1995-01-31

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