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WO1993018146A3 - Proteines formant des complexes avec des chaperones et leurs ligands, leurs fragments, leur obtention et leurs applications biologiques - Google Patents

Proteines formant des complexes avec des chaperones et leurs ligands, leurs fragments, leur obtention et leurs applications biologiques Download PDF

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Publication number
WO1993018146A3
WO1993018146A3 PCT/FR1993/000219 FR9300219W WO9318146A3 WO 1993018146 A3 WO1993018146 A3 WO 1993018146A3 FR 9300219 W FR9300219 W FR 9300219W WO 9318146 A3 WO9318146 A3 WO 9318146A3
Authority
WO
WIPO (PCT)
Prior art keywords
chaperones
ligands
fragments
preparation
forming complexes
Prior art date
Application number
PCT/FR1993/000219
Other languages
English (en)
Other versions
WO1993018146A2 (fr
Inventor
Marie-Claire Lebeau
Nelly Massol
Michel Renoir
Christine Radanyi
Jean-Paul Mornon
Isabelle Callebaut
Etienne-Emile Baulieu
Beatrice Chambraud
Original Assignee
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med filed Critical Inst Nat Sante Rech Med
Publication of WO1993018146A2 publication Critical patent/WO1993018146A2/fr
Publication of WO1993018146A3 publication Critical patent/WO1993018146A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention vise des séquences de nucléotides capables de s'hybrider avec la séquence de nucléotides représentée sur la figure 1, ainsi que les séquences d'acides aminés codées correspondantes. Ces séquences de nucléotides sont utiles notamment pour la détection de séquences complémentaires dans des échantillons biologiques.
PCT/FR1993/000219 1992-03-04 1993-03-04 Proteines formant des complexes avec des chaperones et leurs ligands, leurs fragments, leur obtention et leurs applications biologiques WO1993018146A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9202612A FR2688227A1 (fr) 1992-03-04 1992-03-04 Proteines formant des complexes avec des chaperones et leurs ligands, leurs fragments, leur obtention et leurs applications biologiques.
FR92/02612 1992-03-04

Publications (2)

Publication Number Publication Date
WO1993018146A2 WO1993018146A2 (fr) 1993-09-16
WO1993018146A3 true WO1993018146A3 (fr) 1993-11-11

Family

ID=9427364

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1993/000219 WO1993018146A2 (fr) 1992-03-04 1993-03-04 Proteines formant des complexes avec des chaperones et leurs ligands, leurs fragments, leur obtention et leurs applications biologiques

Country Status (2)

Country Link
FR (1) FR2688227A1 (fr)
WO (1) WO1993018146A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8968720B2 (en) 2008-03-20 2015-03-03 University Of Miami Heat shock protein GP96 vaccination and methods of using same
US9238064B2 (en) 2008-03-03 2016-01-19 University Of Miami Allogeneic cancer cell-based immunotherapy

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5997873A (en) * 1994-01-13 1999-12-07 Mount Sinai School Of Medicine Of The City University Of New York Method of preparation of heat shock protein 70-peptide complexes
US5750119A (en) 1994-01-13 1998-05-12 Mount Sinai School Of Medicine Of The City University Of New York Immunotherapeutic stress protein-peptide complexes against cancer
US5646249A (en) * 1994-02-28 1997-07-08 The United States Of America As Represented By The Department Of Health And Human Services Isolation and characterization of a novel chaperone protein
US5961979A (en) * 1994-03-16 1999-10-05 Mount Sinai School Of Medicine Of The City University Of New York Stress protein-peptide complexes as prophylactic and therapeutic vaccines against intracellular pathogens
AU3761695A (en) * 1994-10-14 1996-05-06 Salk Institute For Biological Studies, The Novel immunophilins and corresponding nucleic acids
US5935576A (en) 1995-09-13 1999-08-10 Fordham University Compositions and methods for the treatment and prevention of neoplastic diseases using heat shock proteins complexed with exogenous antigens
US5837251A (en) * 1995-09-13 1998-11-17 Fordham University Compositions and methods using complexes of heat shock proteins and antigenic molecules for the treatment and prevention of neoplastic diseases
US5985270A (en) * 1995-09-13 1999-11-16 Fordham University Adoptive immunotherapy using macrophages sensitized with heat shock protein-epitope complexes
EP0928197B1 (fr) 1996-09-18 2003-03-05 Zetesis S.P.A. Utilisation de proteines comme agents actifs contre des maladies auto-immunes
US6017540A (en) 1997-02-07 2000-01-25 Fordham University Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes
US5830464A (en) 1997-02-07 1998-11-03 Fordham University Compositions and methods for the treatment and growth inhibition of cancer using heat shock/stress protein-peptide complexes in combination with adoptive immunotherapy
IT1290828B1 (it) * 1997-03-25 1998-12-11 Zetesis Spa Uso di proteine estraibili da organi animali per la preparazione di medicamenti per il trattamento di condizioni patologiche
US5948646A (en) * 1997-12-11 1999-09-07 Fordham University Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes
WO1999042121A1 (fr) 1998-02-20 1999-08-26 University Of Miami Complexe peptide antigenique/proteine du stress modifiee
DE19907598A1 (de) * 1999-02-22 2000-08-24 Schulz Burkhard DNA Sequenz kodierend ein FKBP ähnliches Protein, Plasmide, Bakterien, Hefen und Pflanzen enthaltend dieses Protein sowie Mutanten in Arabidopsis für dieses Gen, die in der Ausprägung der Pflanzenarchitektur, der Reaktion gegenüber Brassinosteroiden und ihren Verbindungen und durch Ethylen vermittelten Gravitropismus der Wurzel defekt sind
US6335157B1 (en) 1999-05-07 2002-01-01 The European Molecular Biology Laboratory Method based on localization of Hsp90 to the centrosome
US7449557B2 (en) 2000-06-02 2008-11-11 University Of Connecticut Health Center Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy
AU2002335654B2 (en) 2001-08-20 2008-02-21 University Of Connecticut Health Center Methods for preparing compositions comprising heat shock proteins or alpha-2-macroglobulin
AU2016215175B2 (en) 2015-02-06 2021-09-16 Heat Biologics, Inc. Vector co-expressing vaccine and costimulatory molecules
CA3040123A1 (fr) 2016-10-11 2018-04-19 University Of Miami Vecteurs et cellules de vaccin pour immunite contre le virus zika
WO2018187260A1 (fr) 2017-04-04 2018-10-11 Heat Biologics, Inc. Vaccination intratumorale

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991004321A1 (fr) * 1989-09-25 1991-04-04 President And Fellows Of Harvard College Recepteur pour fk-506
WO1992001052A1 (fr) * 1990-07-11 1992-01-23 Tonen Corporation Adn codant pour une proteine de liaison de fk506 humaine et expression de cet adn

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991004321A1 (fr) * 1989-09-25 1991-04-04 President And Fellows Of Harvard College Recepteur pour fk-506
WO1992001052A1 (fr) * 1990-07-11 1992-01-23 Tonen Corporation Adn codant pour une proteine de liaison de fk506 humaine et expression de cet adn

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BIOCHEMISTRY. vol. 29, no. 21, 1990, EASTON, PA US pages 5145 - 5152 SANCHEZ R. ET AL. 'The 56-59-kilodalton protein identified in untransformed receptor complexes is...' cité dans la demande *
GENBANK DATABASE,BETHESDA US Acc.No.x17069,Nelki S. al.:'Identification and DNA sequence of a family of related cDNA's one of which is haploid specific and...' *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9238064B2 (en) 2008-03-03 2016-01-19 University Of Miami Allogeneic cancer cell-based immunotherapy
US8968720B2 (en) 2008-03-20 2015-03-03 University Of Miami Heat shock protein GP96 vaccination and methods of using same

Also Published As

Publication number Publication date
WO1993018146A2 (fr) 1993-09-16
FR2688227A1 (fr) 1993-09-10

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