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WO1992005753A1 - Materiaux elastomeres ou rigides capables de transmettre les microcourants electriques - Google Patents

Materiaux elastomeres ou rigides capables de transmettre les microcourants electriques Download PDF

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Publication number
WO1992005753A1
WO1992005753A1 PCT/US1991/007096 US9107096W WO9205753A1 WO 1992005753 A1 WO1992005753 A1 WO 1992005753A1 US 9107096 W US9107096 W US 9107096W WO 9205753 A1 WO9205753 A1 WO 9205753A1
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WO
WIPO (PCT)
Prior art keywords
biocompatible material
latex
butanol
propanol
fibers
Prior art date
Application number
PCT/US1991/007096
Other languages
English (en)
Inventor
Robert Findley Echols, Jr.
Original Assignee
Echols Robert Findley Jr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909021085A external-priority patent/GB9021085D0/en
Priority claimed from GB909026020A external-priority patent/GB9026020D0/en
Application filed by Echols Robert Findley Jr filed Critical Echols Robert Findley Jr
Publication of WO1992005753A1 publication Critical patent/WO1992005753A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B10/0058—Devices for taking samples of body liquids for taking sperm samples
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B42/00—Surgical gloves; Finger-stalls specially adapted for surgery; Devices for handling or treatment thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/02—Contraceptive devices; Pessaries; Applicators therefor for use by males
    • A61F6/04—Condoms, sheaths or the like, e.g. combined with devices protecting against contagion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/12—Mammary prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2/2803—Bones for mandibular reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2821—Bone stimulation by electromagnetic fields or electric current for enhancing ossification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30563—Special structural features of bone or joint prostheses not otherwise provided for having elastic means or damping means, different from springs, e.g. including an elastomeric core or shock absorbers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/307—Prostheses for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0081—Prosthesis for animals

Definitions

  • the present invention is directed to materials capable of transmitting electrical currents naturally found in the bioelectric system of human beings and animals, which material in normal use is impermeable to passage of bacteria or viruses, and articles and prosthetic devices made from them for use with human beings and animals.
  • the material according to the invention is a natural or synthetic polymer material having the physical characteristics of rubber or latex or combinations thereof and also rigid polymers as set forth herein for medical and other uses which bar the passage of bacteria or viruses in normal use and permits the passage of currents of the order of the bioelectric system of the human body and other mam alian bodies, and also the discharge of static electricity which is desirable in surgical operating rooms and clean room work and all other uses for an electrically conductive elastomer. Also, there are rigid, not elastomeric polymers which may be made conductive.
  • polystyrene acrylonitrile butadiene styrene
  • ABS acrylonitrile butadiene styrene
  • PET polyethylene terephthalate
  • EPDM silicone rubber
  • KRATONTM polymethylmethacrylate
  • P A polypropylene
  • PP polyacetal
  • polyamids NYLON 6,66,6/10,12 cellulose acetate
  • polytetrafluroethylene TeflonTM.
  • the material, elastomeric synthetic polymer useful in medicine or latex may have dispersed throughout either carbonaceous filamentous fibers, natural silk fibers or other fibers or combinations thereof capable of conducting electricity with very little resistance when moistened by an electrolyte.
  • carbon filaments ranging from approximately 10-5 millimicrons in diameter up to approximately 2,000 millimicrons or more in length can be dispersed throughout.
  • the fibers can be relatively kinked or coiled or folded so that the material can be stretched.
  • a thin sheet of pure elastomer or polymeric material on each side of the filament containing sheet can be provided.
  • the fibers may be omitted, if desired.
  • the hard polymers are conductive but may be carbon particles, if desired.
  • Figure 1 illustrates a cross section of a sheet of material not requiring stretching or friction resistance properties.
  • Figure 2 illustrates a nonper eable sheet of material which can be stretched and which prevents passage of bacteria, virus or fluids.
  • Figure 3 is a cross section illustrating a prosthetic device which is biocompatible, for example, a chin implant.
  • Figure 4 is the biocompatible material without filaments capable of transmitting microcurrents of the bioelectric system of human beings and animals.
  • Figure 5 illustrates a condom made of the material of Figures 2 or 4.
  • Figure 6 illustrates gloves made from a biocompatible material of Figures 2 or 4 usable in medicine for surgeons, dentists, medical technicians, veterinarians, and the like.
  • Figure 7 is a fragmentary perspective view of a vascular prosthesis made from a conductive medical polymer.
  • Figure 8 is a cross-sectional view of an orthopedic prosthesis having a conductive medical polymer outer coating.
  • Figure 9A is a front view and Figure 9B is a side view of an electrically conductive implantable lens.
  • Figure 10A is a side view and Figure 10B is a front view of an electrically conductive breast implant. Best Mode for Carrying out the Invention
  • the material, products, and prostheses can be made by mold dipping, spraying the material on molds or injection molding with the electrically-conductive filaments or fibers dispersed in the material. In some cases, elastomer without filaments is applied on surfaces, such as by dipping or spraying.
  • the electrically conductive fibers or filaments can be carbonaceous or silk, nylon, dacron, rayon or other filaments moistened with an electrolyte, such as sodium chloride, potassium chloride as found in human blood, which are electrically conductive in a highly humid atmosphere.
  • the carbonaceous filaments should comprise from about 5 percent to 65 percent dry weight of the material if used alone.
  • the silk alone or with other fibers in combination (no carbonaceous material) should comprise about 1 percent to about 55 percent dry weight of the material.
  • the filaments or fibers should be coiled or kinked or folded accordion style.
  • the resulting fiber encasing material has extremely low resistance to electric current, particularly in thin sheets.
  • the electrical resistance is so low that the microcurrents sufficient for the firing of nerve cells actually "jump the gap" on the 4/1,000 inch film when liquid electrolyte is present on both sides of the elastomeric material.
  • the pure non-fiber material of natural latex or synthetic polymer of Figure 4 produced as described subsequently has resistance in ranges of 2000 ohms for 4/1000 inch of thickness of the material.
  • the resistance is in the range of 300-320 OHMS.
  • the material is also a barrier to bacteria or viruses (Figure 2) .
  • the electric resistance does not increase appreciably with stretching of the material. Wherever there are living cells, there is electrical function.
  • This material provides a physical barrier to the passage of bacteria or viruses while permitting electrical functions to continue through the material in almost a normal manner.
  • the antistatic function of the material will help prevent any explosive potential, for example, in operating rooms, chemical plants, and the like. Also, antistatic prevention on electronics, particularly in clean rooms, will be superior. Powdered or especially liquid electrolytes optimize conductivity when used on the surfaces of the elastomeric material. Because of its electrical conductivity, the material is especially suited for both male and female condoms, such as illustrated in Figure 5. As set forth in The Bioelectrical Investigation of Sexuality and Anxiety, Wilhelm Reich, Farrar, Straus and Giroux, New York, 1982, "sexual excitation is functionally identical to the bioenergetic charge of the erogenous zones. Anxiety excitation goes together with a decrease in the surface charge.
  • the sexual function is one of the general electrical processes that occur in nature.
  • the erogenous zones are capable of registering extremely intense sensation and of generating high bioelectrical charge.
  • a higher electrical potential also corresponds to a more intense state of excitation, which is experienced subjectively as a more intense sensation of excitation or current.
  • the arrangement of membranes, boundary surfaces ' , and fluids during sexual intercourse indicates that a complete electrolytic system has been established.
  • the surface of the penis must be seen as one electrode and the vaginal mucosa as the other.
  • the present invention is also well adapted and suited for the collection of semen for artificial insemination for both human and in animal husbandry, i.e., champion bulls, thoroughbred horses, etc. and optimizes physiology in ways not fully understood at the present time, as though the bioelectric circuit was completed as in nature.
  • the present invention is applicable to all devices, prostheses and the like requiring the properties of elasticity or flexibility and electrical conductivity in a solid, three-dimension mass of materials as, for example, plastic surgeons* prosthetic devices, chin implants, ( Figure 3), breast augmentation, etc.; also oral and maxillo-facial surgeon implant materials such as maxillary or mandibular ridge implants in edentulous patients.
  • biocompatibility of this highly conductive material is much more acceptable and compatible for mammalian body items, for example, interuterine devices (IUDs) .
  • rigid polymers may be made electrically conductive by including n-propanol and n-butanol.
  • Figure l illustrates electrically conducting sheeting 10 with short 12 and long 14 coiled electrically conducting fibers not requiring stretching or friction resistance properties.
  • Figure 2 illustrates a sheet 15 which is impermeable to physical items such as bacteria, virus or sperm and is composed of the sheet 10 of Figure 1 having an outer coating or layer 16 of elastomer dipped or sprayed on the sheet 10.
  • Figure 3 illustrates a prosthesis, a superior portion of a chin implant 18 formed of the material 10 of Figure l and coated with a pure elastomer layer 16.
  • Figure 4 illustrates a sheet 20 of an electrically conductive medical polymer without fibers according to the invention.
  • Figure 5 illustrates a condom 21, which can be for male or female, made of the material of Figures 2 or 4.
  • the condom 20 can be for animal husbandry, sperm collection, animal breeding purposes and the like.
  • a glove 22 is illustrated made of electrically conductive material according to the invention.
  • the glove can be used for surgical, general medical, dental, veterinary medicine and clean rooms.
  • the invention is applicable to the full range of medical, dental, veterinary medicine fields for artificial organs and prosthetic devices, which include hard, rigid types, soft elastomer types, combinations of both types and any of the foregoing with metal as needed.
  • Figure 7 illustrates a vascular prosthesis 24 formed of an electrically conductive medical polymer.
  • Figure 8 illustrates an orthopedic joint prosthesis 26 having a metal core 28, an insulating layer 30 covered with a layer of electrically conductive medical polymer.
  • Figures 9A and 9B illustrate a soft lens implant 34, and
  • Figures 10A and 10B illustrate a soft breast implant 36 made of the electrically conductive materials of the invention.
  • Combinations of the electrically conductive medical material with metal are primarily for but not limited to orthopedic prosthesis.
  • the metal is preferably non-magnetic covered with an insulating material 30 ( Figure 8) which can be any compatible material, such as TeflonTM, and the outermost layer 32 is the conductive material. Titanium or titanium alloy is preferred. TeflonTM or other appropriate material is used to cover screws or asteners, and, if feasible, titanium screws are preferred with titanium bodies.
  • Examples of combinations of hard and soft polymers include facial reconstruction with a hard polymer replacing bone and soft conductive polymer replacing the overlying soft tissue. Also, a bone and joint prosthesis with the bone of hard polymer and the articulating surfaces of the joint of softer electrically conductive polymer mimicking cartilage properties. A synovial fluid analog serves as the lubricant.
  • the hard polymers by their nature are limited to decreased electrical resistance. The invention is applicable to all medical prosthesis and organs including cardiovascular, neurosurgical, orthopedic, plastic surgery, dental, sensory and metabolic prosthesis.
  • the silk fibers are naturally occurring triangular shaped (in cross section) filaments usually .00020 inches in diameter.
  • the synthetic fibers may be (in cross section) round, square, rectangular bands, irregular or triangular shaped in the range of .0001 inches to .002 inches in 'diameter.
  • the ideal is .00020 inches in diameter.
  • Fibers should be in "bundles” or a “thread” of about seven fibers.
  • threads or bundles for the thin sheet material i.e. gloves, condoms, dental rubber dams, etc.
  • These threads or bundles for the thin sheet material have a length equal to the thickness of the material. (Example: If 4/1000 inches thick material, use 4/1000 inch length bundles.)
  • one-eighth of the fibrous threads uniformly distributed has a length seven times the length of the shorter fibers.
  • Implant materials have fibers in the same order of size.
  • the fibrous bundles (threads) of filaments are to be saturated with an electrolyte of biocompatible nature and concentration.
  • the electrolyte formula and concentration are not harmful or irritating to human skin (integument) or mucous tissue, even for protracted periods (as a surgical implant would have) .
  • Gloves or condoms male or female, human or animal
  • the saturated bundles are then blotted so they are moist, not dripping wet, and then incorporated into the elastomer at a temperature that is low enough so as not to dry the fibers.
  • Any desired type of electrolytes can be used, such as gels used in making electrical connections to humans in medical testing or sodium chloride or potassium chloride solutions as found in the blood of warm blooded vertebrates.
  • This compartment (within the elastomer) of electrolyte dampened fibers forms a humidor and gives both a conductive property and a capacitor-like function for microcurrents.
  • the relative humidity within this micro chamber should be as high as fabrication techniques will permit, a range of 97, 98 or 99% at body temperature. Therefore, a relatively low fabrication temperature is specified to fulfill this requirement.
  • the multitude of humidor-chambers (filled with electrolyte moistened fibers) is separated from each other, in the main, by capillary walls of elastomer.
  • the capacitor-like effect of the compartments store and build up the current and then effect the current required to jump the gap of the capillary-like walls. This is the basis of the microcurrent transmission with fibers or filaments.
  • the non-fibrous materials of the invention are elastomeric and nonelasto eric materials and the medical polymers previously referred to possessing resistance in the range of 500 ohms per 1/1,000 inch thickness of material. These materials may be classified under the headings of Natural Rubber type and Synthetic type polymers, such as natural rubber, polyurethane, butylrubber (IIF) , neoprene (CCR) , nitrile rubber (NBR) , polyethylene (PE) , polyvinyl alcohol (PVAV) , polyvinyl chloride (PVC) , ethylene vinyl alcohol (PE/EVAL) , TeflonTM (PTFE) , VitronTM (FPM) , SaranexTM
  • Natural Rubber type and Synthetic type polymers such as natural rubber, polyurethane, butylrubber (IIF) , neoprene (CCR) , nitrile rubber (NBR) , polyethylene (PE) , polyvinyl alcohol
  • PVDC/PE Vinyl Visco/PE
  • other materials having the physical properties of rubber or latex.
  • Example 1 The following examples set forth current best modes of preparing the electrically conductive material.
  • a natural rubber material is made with petrochemical origin n-butanol.
  • n-butanol a solution of three alcohols totaling 6 to 14% by volume and natural Latex with the balance water (with solids by weight of 30 to 66%) .
  • the alcohol solution which is used with the petrochemical based butanol only, is made up of 8 to 15% of plant origin (only) ethanol; 3 to 7% n-propanol of either petrochemical or plant origin; and the balance of petrochemical based n-butanol.
  • the natural rubber material was combined with vegetable or animal origin n-butanol.
  • the solution contained two alcohols totaling 6 to 14% by volume and natural latex of 30 to 66% solids by weight and the balance water to 100%.
  • the alcohols comprise from 3 to 7% n-propanol of either petrochemical or vegetable origin with the balance being the vegetable origin n-butanol of a special method of extraction, as later described.
  • Example 3 The synthetic type material is composed of either of the above two alcohol solutions comprising 6 to 14% by volume with 30 to 60% polyurethane by weight and the balance water.
  • Example 4 Presently preferred methods of making these materials include the following. Physically separate (distill) ethanol from products of the selective bacterial fermentation of carbohydrate containing materials such as grains, molasses, or sugars as cane or beet sugar.
  • the ethanol used must be of vegetable origin to gain the unique high solubility between latex and alcohol needed between the vegetable origin latex and the mineral origin of petrochemical n-butanol and n-propanol.
  • Natural latex normally coagulates and is unusable upon the addition of approximately 5% of butanols or other complex alcohols, (propanol or longer chain) .
  • the absorption of butanol is in the range of 12% and higher.
  • n-butanol If the alternative method of using plant origin n-butanol " is used, the fermentation and distillation of carbohydrates will provide this n-butanol. However, since the temperature of 110°C is never to be exceeded with any of the ingredients used, and the boiling point of n-butanol is 117.7°C, a partial vacuum distillation must be needed.
  • Latex should be at room temperature or refrigerated, preferably to 42°F and the solution of alcohols refrigerated to 32°F prior to mixing. The solutions should not be exposed to magnetic fields or electrical fields. Use glass or ceramic preferably, or plastic or nonmagnetic metal vessels for all solutions preferably 24 hours prior to experiment, and do not place solutions closer than eight inches to ferrous or other magnetic metals before or during incorporation of ingredients.
  • Ethanol is to be of organic origin and physically separated (i.e. distilled from natural, not artificially fortified wine or other organic material containing ethanol) when using natural latex. Ethanol can be of petrochemical origin when using polyurethane.
  • Organic origin n-butanol and n-propanol are preferred ingredients, but if unobtainable, these two ingredients can be of petrochemical origin.
  • Example 7 The purpose of this experiment was to determine the amount of alcohol solution mix (ethanol - 10%, n-butanol - 85% and n-propanol - 5%) that can be added to 30% total solids natural rubber latex without any coagulation.
  • Alcohol Solution Mix Formulation ethanol 10% 20 ml n-butanol 85% 170 ml n-propanol 5% 10 ml
  • Latex-Alcohol Compounding Alcohol mix from part C was added to the latex at a rate of 1.6 ml/minute.
  • condoms were made using the natural rubber latex-alcohol compound.
  • Latex-Alcohol Compounding Repeated the procedures given in Example 7 by adding 75 ml alcohol mix into 750 ml of compounded latex.
  • Examples 6, 7 and 8 There was no latex coagulation in Examples 6, 7 and 8.
  • the condoms were made by dipping a glass former into the alcohol-latex compound and drying it in an oven at 70°C until the rubber film became translucent and free from whiteness. The outside was dusted with talc powder and it was stripped from the former by dusting the inside to prevent stickiness.
  • Example 9 In this example fibers as previously described are incorporated in the latex material which provides a satisfactory material capable of conducting microcurrents of the order of the bioelectric system of the human and other mammalian bodies and also discharges static electricity.
  • the electrically conductive material can be used for a wide variety purposes, such as conductive rubber sheeting for general medical, surgical, dental, veterinary medicine and associates fields. It is useful as a viral and bacterial barrier while conducting normal body surface electrical currents; for example, as in holding and nurturing of infected infants and children while allowing exchange and balancing of normal body currents.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Prostheses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

L'invention se rapporte à des matériaux élastomères et rigides biocompatibles (10), qui ont le pouvoir de transmettre les microcourants du système bioélectrique chez l'homme et chez les animaux et qui, s'ils sont utilisés normalement, ne laissent pas passer les bactéries ou les virus, à des articles et à des dispositifs de prothèses fabriqués à partir de ces matériaux (10) et utilisables chez l'homme et chez les animaux, ainsi qu'à leurs procédés de fabrication.
PCT/US1991/007096 1990-09-27 1991-09-27 Materiaux elastomeres ou rigides capables de transmettre les microcourants electriques WO1992005753A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9021085.7 1990-09-27
GB909021085A GB9021085D0 (en) 1990-09-27 1990-09-27 Elastomeric materials,articles and prostheses with low resistance to bioelectric currents of human and animals and static electricity
GB9026020.9 1990-11-29
GB909026020A GB9026020D0 (en) 1990-11-29 1990-11-29 Elastomeric materials,articles and prostheses with low resistance to bioelectric currents of human and animals and static electricity

Publications (1)

Publication Number Publication Date
WO1992005753A1 true WO1992005753A1 (fr) 1992-04-16

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1991/007096 WO1992005753A1 (fr) 1990-09-27 1991-09-27 Materiaux elastomeres ou rigides capables de transmettre les microcourants electriques

Country Status (2)

Country Link
EP (1) EP0550694A4 (fr)
WO (1) WO1992005753A1 (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999046002A1 (fr) * 1998-03-13 1999-09-16 Intermedics Inc. Boitier de defibrillateur a revetement polymere conducteur
WO2001058394A1 (fr) * 2000-02-11 2001-08-16 Michaela Buske Preservatif
US6863070B2 (en) * 2003-04-16 2005-03-08 George Shapiro Magnetic condom
WO2015068174A3 (fr) * 2013-11-11 2015-10-15 Hll Lifecare Limited Composites polymères à base de graphène pour la production de préservatifs présentant un transfert thermique élevé, une sensibilité améliorée et une capacité d'administration de médicament
US9314321B2 (en) 2007-09-05 2016-04-19 Biolectrics Llc Concurrent treatment of oral and systemic maladies in animals using electrical current
US10201698B2 (en) 2014-01-07 2019-02-12 Animal Oralectrics Llc Systems and methods for the treatment of oral and systemic maladies in animals using electrical current
US10213598B2 (en) 2007-09-05 2019-02-26 Bioelectrics Llc Systems and methods for reducing or altering oral bacteria and methods for manufacturing the same
US12064619B2 (en) 2020-07-28 2024-08-20 Biolectrics Llc Systems and methods related to intraoral electrical stimulation

Citations (2)

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US4789720A (en) * 1988-03-09 1988-12-06 Tyndale Plains-Hunter, Ltd. Hydrophilic polyurethanes prepared from mixed oxyalkylene glycols
US5076278A (en) * 1990-10-15 1991-12-31 Catheter Technology Co. Annular ultrasonic transducers employing curved surfaces useful in catheter localization

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DE3674086D1 (de) * 1985-07-03 1990-10-18 Mitsuboshi Belting Ltd Druckempfindlicher leitfaehiger gummiwerkstoff.
DE3706061A1 (de) * 1987-02-19 1990-07-05 Felix Friedmann Praeservativ od. aehnliche vorrichtungen od. geraete aus elastischem material (folie etc.) zur uebertragung physikalischer, insbes. elektrischer und elektromagnetischer phaenomene

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4789720A (en) * 1988-03-09 1988-12-06 Tyndale Plains-Hunter, Ltd. Hydrophilic polyurethanes prepared from mixed oxyalkylene glycols
US5076278A (en) * 1990-10-15 1991-12-31 Catheter Technology Co. Annular ultrasonic transducers employing curved surfaces useful in catheter localization

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP0550694A4 *

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6295474B1 (en) 1998-03-13 2001-09-25 Intermedics Inc. Defibrillator housing with conductive polymer coating
US6718628B2 (en) 1998-03-13 2004-04-13 Intermedics Inc. Method of making a stimulator electrode with a conductive polymer coating
US6856840B2 (en) 1998-03-13 2005-02-15 Intermedics, Inc. Ionically conductive polymeric composition
WO1999046002A1 (fr) * 1998-03-13 1999-09-16 Intermedics Inc. Boitier de defibrillateur a revetement polymere conducteur
WO2001058394A1 (fr) * 2000-02-11 2001-08-16 Michaela Buske Preservatif
US6863070B2 (en) * 2003-04-16 2005-03-08 George Shapiro Magnetic condom
US10617502B2 (en) 2007-09-05 2020-04-14 Biolectrics Llc Concurrent treatment of oral and systemic maladies using direct current electricity
US9314321B2 (en) 2007-09-05 2016-04-19 Biolectrics Llc Concurrent treatment of oral and systemic maladies in animals using electrical current
US9877816B2 (en) 2007-09-05 2018-01-30 Bioelectrics Llc Concurrent treatment of oral and systemic maladies using direct current electricity
US10946188B2 (en) 2007-09-05 2021-03-16 Biolectrics Llc Systems and methods for treatment of an oral cavity
US10213598B2 (en) 2007-09-05 2019-02-26 Bioelectrics Llc Systems and methods for reducing or altering oral bacteria and methods for manufacturing the same
WO2015068174A3 (fr) * 2013-11-11 2015-10-15 Hll Lifecare Limited Composites polymères à base de graphène pour la production de préservatifs présentant un transfert thermique élevé, une sensibilité améliorée et une capacité d'administration de médicament
US10201698B2 (en) 2014-01-07 2019-02-12 Animal Oralectrics Llc Systems and methods for the treatment of oral and systemic maladies in animals using electrical current
US11324946B2 (en) 2014-01-07 2022-05-10 Animal Oralectrics Llc Systems and methods for the treatment of oral and systemic maladies in animals using electrical current
US12064619B2 (en) 2020-07-28 2024-08-20 Biolectrics Llc Systems and methods related to intraoral electrical stimulation

Also Published As

Publication number Publication date
EP0550694A1 (fr) 1993-07-14
EP0550694A4 (en) 1993-09-15

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