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WO1991018587A1 - Compositions liquides anti-transpiration - Google Patents

Compositions liquides anti-transpiration Download PDF

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Publication number
WO1991018587A1
WO1991018587A1 PCT/US1991/002687 US9102687W WO9118587A1 WO 1991018587 A1 WO1991018587 A1 WO 1991018587A1 US 9102687 W US9102687 W US 9102687W WO 9118587 A1 WO9118587 A1 WO 9118587A1
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WO
WIPO (PCT)
Prior art keywords
antiperspirant
mixtures
centistokes
group
aluminum
Prior art date
Application number
PCT/US1991/002687
Other languages
English (en)
Inventor
Alejandro Cedeno
Joseph Anthony Listro
Original Assignee
The Procter & Gamble Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Procter & Gamble Company filed Critical The Procter & Gamble Company
Priority to BR919106483A priority Critical patent/BR9106483A/pt
Publication of WO1991018587A1 publication Critical patent/WO1991018587A1/fr
Priority to FI925230A priority patent/FI925230A0/fi

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/26—Aluminium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
    • A61K8/585—Organosilicon compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89—Polysiloxanes
    • A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone

Definitions

  • the present invention relates to unique clear, sprayable, liquid antiperspirant compositions having viscosities of less than about 15 centistokes and which provide excellent antiperspirancy and cosmetic in-use properties.
  • Antiperspirant compositions have become part of many people's personal care and grooming regimen.
  • the formulation of such compositions generally is an exercise in efficacy and aesthetic trade-offs, with the resulting composition being acceptable overall, but not outstanding.
  • the formulation of a composition to give it good usage aesthetic properties e.g., minimized residue on the skin, and/or a clean, dry and non-sticky feel
  • Nonaerosol pump spray antiperspirant compositions in general, are known, having been disclosed in, for example, U.S. Patent 4,053,581, Pader et al., issued October 11, 1977; U.S. Patent 4,065,564, Miles, Jr., issued December 27, 1977; U.S. Patent 4,073,880, Pader et al., issued February 14, 1978; and Great Britain Application 1,536,222, published December 20, 1978.
  • Such compositions comprise high levels of an alcohol solvent. Formulation in such a way generally results in products with poor in-use characteristics, i.e., residue on skin, sticky, cold feel, and stinging upon application.
  • the present invention relates to clear, sprayable, liquid antiperspirant solutions, having a viscosity of less than about 15 centistokes, comprising: a. from about 10% to about 25% of a monohydric alcohol-sol ⁇ uble antiperspirant salt; b. from about 3% to about 10% of a non-volatile silicone emollient having a viscosity of from about 1 centistoke to about 50 centistokes and a solubility parameter of from about 4 to about 9; c.
  • a volatile silicone emollient having a viscosity of from about 0.65 centistokes to about 10 centistokes and a solubility parameter of from about 4 to about 9; d. from about 5% to about 20% of a non-volatile emollient ester having a solubility parameter of from about 7 to about 10; e. from about 1% to about 12% of a solubilizer comprising an agent selected from the group consisting of ethoxylated and propoxylated nonionic surfactants having an HLB of from about 5 to about 18, and mixtures thereof; such that the average HLB of the solubilizer is from about 8 to about 14; and f.
  • a preferred composition of the present invention comprises a clear, sprayable, liquid antiperspirant solution, having a viscosity of less than about 15 centistokes, comprising: a. from about 14% to about 16% of an ethanol-soluble sesquichlorohydrate antiperspirant salt; b. from about 3% to about 10% of a non-volatile silicone emollient selected from the group consisting of phenyl dimethicone, phenyl trimethicone, dimethicone fluids having viscosities of from about 1 centistoke to about 10 centistokes, and mixtures thereof; c.
  • a volatile silicone emollient selected from the group consisting of D4-05 cyclomethicones, phenethyl pentamethyl disiloxane, dimethicone fluids having viscosities of less than 1 centistoke, and mixtures thereof; d. from about 9% to about 11% of a non-volatile emollient selected from the group consisting of C 12 -C 15 alcohols benzoate, isopropyl myristate, isopropyl palmitate, and mixtures thereof; e. from about 1% to about 2% of a solubilizer which is selected from the group consising of:
  • ethoxylated nonionic surfactant materials selected from the group consisting of compounds of the formula:
  • a critical component of the present compositions is an antiperspirant material that is soluble and which remains soluble in ethanol or another suitable monohydric alcohol solvent. Solubilization of the antiperspirant material allows for the formulation of the present clear antiperspirant solutions.
  • Patent 3,523,130 Jones et al., issued August 4, 1970; U.S. Patent 3,555,146, Jones et al., issued January 12, 1971; U.S. Patent 3,876,758, Beekman, issued April 8, 1975; Great Britain Patent Specifications 1,159,685 and 1,159,686, both published July 30, 1969, Armour Pharmaceutical Company; and European Published Patent Application, 7,191, published January 23, 1980, Unilever Limited.
  • Salts useful as astringent antiperspirant salts or as components of astringent complexes include aluminum halides, aluminum hydroxyhalides, zirconyl oxyhalides, zirconyl hydroxyhalides, and mixtures of these salt materials.
  • Aluminum salts of this type can be prepared in the manner described more fully in U.S. Patent 3,887,692, Gil an, issued June 3, 1975, and U.S. Patent 3,904,741, Jones and Rubino, issued September 9, 1975, incorporated herein by reference.
  • zirconium compounds which may be used in the present invention include both zirconium oxy salts and zirconium hydroxy salts, also referred to as the zirconyl salts and zirconyl hydroxy salts. These compounds may be represented by the following general empirical formula:
  • nz B z wherein z may vary from about 0.9 to about 2 and need not be an integer; n is the valence of B; 2-nz is greater than or equal to 0; and B may be selected from the group consisting of halides (preferably chloride), nitrate, sulfa ate, sulfate, and mixtures thereof.
  • the above formula is greatly simplified and is intended to represent and include compounds having coordinated and/or bound water in various quantities, as well as polymers, mixtures and complexes of the above.
  • the zirconium hydroxy salts actually represent a range of compounds having various amounts of the hydroxy group, varying from about 1.1 to only slightly greater than 0 groups per molecule.
  • antiperspirant complexes utilizing the above antiperspirant salts are known in the art.
  • U.S. Patent 3,792,068, Luedders et al . issued February 12, 1974, discloses complexes of aluminum, zirconium, and amino acids such as glycines.
  • ZAG complexes such as those disclosed in the Luedders et al . patent and other similar complexes are commonly known as ZAG.
  • ZAG complexes are chemically analyzable for the presence of aluminum, zirconium, and chlorine.
  • ZAG complexes useful herein are identified by the specification of both the molar ratio of aluminum to zirconium (hereinafter "Al:Zr” ratio) and the molar ratio of total metal to chlorine (hereinafter “Metal :C1" ratio).
  • Al:Zr the molar ratio of aluminum to zirconium
  • Metal :C1 molar ratio of total metal to chlorine
  • ZAG complexes useful herein have an Al:Zr ratio of from about 1.67 to about 12.5 and a Metal :C1 ratio of from about 0.73 to about 1.93.
  • Preferred ZAG complexes are formed by (A) co-dissolving in water
  • p parts neutral amino acid selected from the group consisting of glycine, dl-tryptophane, dl-0-phenyl- alanine, dl-valine, dl- ethionine, and J-alanine, and where p is from about 0.06 to about 0.53;
  • a preferred aluminum compound for preparation of such ZAG type complexes is aluminum chlorhydroxide of the empirical formula A1 2 (0H) 5 C1 '2H 2 0.
  • Preferred zirconium compounds for preparation of such ZAG-type complexes are zirconyl hydroxychloride having the empirical formula Zr0(0H)Cl -3H 2 0 and the zirconyl hydroxyhalides of the empirical formula Zr0(0H) 2 . a Cl 2 'nH 2 0 wherein a is from about 1.5 to about 1.87, and n is from about 1 to about 7.
  • the preferred amino acid for preparing such ZAG-type complexes is glycine of the formula CH 2 (HN 2 )C00H. Salts of such amino acids can also be employed in the antiperspirant complexes. See U.S. Patent 4,017,599, Rubino, issued April 12, 1977, incorporated herein by reference.
  • U.S. Patent 3,981,896, issued September 21, 1976 discloses an antiperspirant complex prepared from an aluminum polyol compound, a zirconium compound and an organic buffer.
  • Patent 3,970,748, Mecca issued July 20, 1976, discloses an aluminum chlorhydroxy glycinate complex of the appropriate general formula [A1 2 (0H) 4 C1][H 2 CNH 2 - COOH]. All of these patents are incorporated by reference herein.
  • preferred compounds include the 5/6 basic aluminum salts of the empirical formula A1 2 (0H) 5 C1 -2H 2 0; mixtures of A1C1 3 -6H 2 0 and
  • antiperspirant actives useful in the compositions of the present invention are antiperspirant actives with enhanced efficacy due to improved molecular distribution.
  • Aluminum chlorhydroxide salts, zirconyl hydroxychloride salts, and mixtures thereof having improved molecular distributions are known, having been disclosed, for example, in the following documents, all incorporated by reference herein: U.S. Patent 4,359,456, Gosling et al .
  • the antiperspirant actives utilized have enhanced efficacy due to improved molecular distribution with a ratio of peak 4 to peak 3 greater than about 0.1:1 as determined by gel permeation chromatography.
  • This ratio as is recognized by one skilled in the art, relates to the relative area under those two peaks as measured by the gel permeation chromatography analysis method.
  • Highly desirable antiperspirant salts for use herein are selected from the group consisting of aluminum chlorohydrex (sold under the name Rehydrol*, by Reheis Chemical Company), aluminum chlorohydrex PEG, aluminum chlorohydrex PG, aluminum sesqui- chlorohydrate, aluminum sesquichlorohydrex PEG, aluminum sesquichlorohydrex PG, and mixtures thereof. All of these materials are particularly safe for use in spray-on compositions.
  • the most preferred antiperspirant salt for use herein is aluminum sesquichlorohydrate.
  • the antiperspirant salt is present in the liquid antiperspirant compositions of the present invention at a level of from about 10% to about 25%, preferably from about 14% to about 16%. These weight percentages are calculated on an anhydrous metal salt basis (exclusive of glycine, the salts of glycine, or other co plexing agents).
  • Solvent for the Antiperspirant Salt The antiperspirant salts of the present invention are solubilized in a solvent. Suitable solvents include monohydric alcohols, especially C 2 -C 4 monohydric alcohols. The preferred solvent for use herein is ethanol. A small amount of water is also necessary in the present compositions to solubilize the antiperspirant material. However, the present compositions will comprise no more than about 5%, preferably no more than about 2.5%, water.
  • the solvent is present in the compositions of the present invention at a level at least sufficient to solubilize the antiperspirant salt. It is desirable to keep the level of monohydric alcohol solvent in the present compositions low to allow for the incorporation of as much emollient materials as possible. This results in a product with improved in-use charac ⁇ teristics. Generally, the solvent is present in the compositions at a level of from about 30% to about 50%, preferably from about 43% to about 47%. Emollients
  • the * present antiperspirant composition also comprise large amounts of non-volatile emollient esters and volatile and non-volatile silicone emollients. It is these components that are primarily responsible for the desirable product aesthetics and in-use characteristics of the present compositions. For example, these components provide the smooth, clean, dry, non-sticky feel upon application to the skin. These components are present in the antiperspirant compositions at relatively high levels to maximize these benefits. Generally, these components are present at a total level of from about 20% to about 35%, preferably from about 24% to about 33%.
  • emollient materials must have a viscosity in the range of from about 0.65 centistokes to about 50 centistokes as measured by a Brookfield* cone and plate viscometer, at ambient temperature (or other suitable methods). These emollient materials must also be of a certain polarity to remain stable in the present compositions, i.e., they must have a solubility parameter (units equal (cal/cm 3 ) 1 / 2 ) in the range of from about 4 to about 10, preferably from about 5 to about 9.
  • solubility parameter is defined in the Polymer Handbook 3rd Ed. (John Wiley and Sons, New York), J Brandrup and E.H. I mergut, Chapter VII, PP. 519-559, as the square root of the cohesive energy density and describes the attractive strength between molecules of the material. Solubility parameters may be determined by measurement, correlations with other physical properties, or indirect measurement. The solubility parameters for the present emollient materials were determined by surface tension measurement as outlined in Vaughan, CD., J. Soc. Cosmet. Chem. , 36, 319-333, 1985. Part of the emollient material of the present compositions comprises a non-volatile emollient ester.
  • This material may comprise C 12 -C 15 alcohol benzoates; esters, diesters, or tetra- esters of C 2 -C 20 alcohols and C 6 -C 16 fatty acids (e.g. diisopropyl sebacate, diisopropyl adipate, lauryl lactate, myristyl yristate, and pentaerythrityl tetrapelargonate) ; and mixtures thereof, which meet the solubility parameter requirement described above.
  • the preferred of these non-volatile emollient materials are esters, diesters, and tetraesters of C 2 -C 20 alcohols and C 6 -C 16 fatty acids.
  • isopropyl myristate isopropyl palmitate
  • C 12 -C :5 alcohols benzoate and mixtures thereof.
  • the most preferred of these emollient esters for use herein are C 12 -C 15 alcohols benzoate.
  • the present compositions comprise these non-volatile emollient ester materials.
  • the non-volatile emollient ester component of the present compositions has a solubility parameter of from about 7 to about 10.
  • the emollient material of the antiperspirant compositions of the present invention also comprises silicone emollient materials.
  • silicone emollient materials used herein must also meet the particular emollient viscosity and solubility parameter requirements as outlined above.
  • Patent 4,673,570 Soldati, issued June 16, 1987; U.S. Patent 4,559,226, Fogel , issued December 17, 1985; U.S. Patent 4,435,382, Shin et al . , issued March 6, 1984; European Patent Office Application 343,843, published November 29, 1989; Great Britain Patent Application 1,536,222, published December 20, 1978; Great Britain Patent Application 2,018,590, published October 24, 1979; and Japanese Published Patent Application 59-152,318, published August 31, 1984.
  • the silicone emollient materials of the present compositions comprise a volatile silicone emollient, having a viscosity of from about 0.65 centistokes to about 10 centistokes, and a solubility parameter of from about 4 to about 9.
  • Certain volatile silicone materials such as cyclic polydimethylsiloxanes containing from about 3 to about 7 silicon atoms, meet these requirements and are useful herein.
  • a description of volatile silicones is found in Todd and Byers, "Volatile Silicone Fluids for Cosmetics", Cosmetics and Toi letries, 91:27-32 (1976), incorporated herein by reference.
  • Other volatile silicones useful herein are taught in U.S. Patent 4,874,868, Bolich, Jr., issued October 17, 1989, incorporated by reference herein.
  • a preferred volatile silicone for use in the present compositions is phenethyl pentamethyl disiloxane.
  • the present compositions comprise from about 5% to about 25%, preferably from about 10% to about 15%, of these volatile silicone materials.
  • the preferred volatile silicone emollient materials of the present invention are D4-D5 cyclomethicones, phenethyl penta ⁇ methyl disiloxane, and mixtures thereof.
  • the present compositions may comprise a volatile dimethicone fluid emollient material, having a viscosity of less than 1 centistoke, preferably 0.65 centistoke, at a level of from about 2% to about 5% of the composition.
  • the silicone emollient materials of the present compositions also comprise non-volatile silicone emollient materials. Such materials have a viscosity of from about 1 to about 50 centi ⁇ stokes, and a solubility parameter of from about 4 to about 9.
  • the present compositions comprise from about 3% to about 10%, preferably from about 3% to about 5%, of such materials.
  • such materials comprise phenyl dimethicone, phenyl trimethicone, non-volatile dimethicone fluids having a viscosity of from about 1 centistoke to about 10 centistokes, and mixtures thereof.
  • surfactant Solubilizer Because the level of emollients is relatively high in the present liquid antiperspirant compositions, formulation of the compositions so that they remain physically and chemically stable over time and a broad range of physical conditions (especially variability in ambient temperature) requires incorporation of certain surfactant solubilizers.
  • solubilizers are primarily responsible for providing product stability.
  • the surfactant solubilizers of the present invention must be soluble in the antiperspirant solvent, must have a low skin irritation potential, must be able to solubilize large amounts of oil phase at temperatures ranging from about -20 * C to about 60 * C, must have an average HLB in the range of from about 8 to about 14, and must, of course, have a low base odor.
  • HLB is fully described, and HLB values for various materials are provided in the publication 7 ⁇ e HLB System, A Time-Saving Guide to E ul si bomb Selection (published by ICI Americas Inc., Wilmington, DE; 1984), the disclosure of this publication being incorporated by reference herein.
  • Silicone-in-water emulsions stabilized by nonionic surfactant emulsifiers having certain HLB values are known, having been disclosed in such references as U.S. Patent 4,874,547, Narula, issued October 17, 1989; U.S. Patent 4,788,001, Narula, issued November 29, 1988; and Great Britain Patent Publication 2,155,337, published September 25, 1985.
  • the present antiperspirant compositions comprise from about 1% to about 12%, preferably from about 1% to about 2%, of a surfactant solubilizer.
  • the solubilizer of the present invention comprises, as a critical component, ethoxylated or propoxylated nonionic surfactant materials, and mixtures thereof. More specifically, the solubilizer comprises an agent selected from the group consisting of ethoxylated and propoxylated nonionic surfactants having an HLB in the range of from about 5 to about 18, or mixtures thereof; such that the average HLB of the solubilizer is from about 8 to about 14. Hence, a single solubilizer material may be used which itself has an HLB in the range of from about 8 to about 14.
  • solubilizer a mixture of materials may be used as the solubilizer herein, each having an HLB in the range of from about 5 to about 18, such that the average HLB of the mixture is from about 8 to about 14.
  • surfactant materials, or mixtures of surfactant materials, with an HLB in this range provide stability across a broad temperature range.
  • these solubilizer materials are selected from the group consisting of ethoxylated or propoxylated fatty acid ethers, and mixtures thereof, so that the average HLB of the solubilizer is from about 8 to about 14.
  • Ethoxylated or propoxylated fatty acid ethers, and mixtures thereof, have been disclosed for use as e ulsifiers in antiperspirant compositions.
  • Highly preferred surfactant solubilizers of the present invention comprise from about 1% to about 2% of materials selected from the group consisting of compounds of the formula:
  • Especially preferred solubilizers for use in the present invention comprise, Steareth-20 alone, at a level of from about 1% to about 2%; or a combination of Ceteth-10 and Ceteth-20, at a ratio of about 1:1, and at a total level of from about 1% to about 2%.
  • compositions of the present invention can also comprise from about 5% to about 8% of other co-solubilizer surfactants.
  • PPG polypropylene glycol
  • C 4 -C 22 preferably C 10 -C 20
  • examples of such materials include PPG-2 myristyl ether, PPG-4 lauryl ether, PPG-10 cetyl ether, PPG-3 myristyl ether, PPG-11 stearyl ether, PPG-15 stearyl ether and mixtures thereof.
  • Preferred co-solubilizers of the present compositions are selected from the group consisting of propylene glycol (n) stearyl ether, where n is on the average from 10-16; and propylene glycol (n) myristyl ether, where n is on the average from 2-10; and mixtures thereof. Most preferred in the present compositions is PPG-3 myristyl ether (HLB about 9.8).
  • Optional components are selected from the group consisting of propylene glycol (n) stearyl ether, where n is on the average from 10-16; and propylene glycol (n) myristyl ether, where n is on the average from 2-10; and mixtures thereof.
  • PPG-3 myristyl ether HLB about 9.8
  • compositions of the present composition may also comprise a number of optional components to provide cosmetic or aesthetic benefits.
  • preservatives, deodorant actives, such as anti- icrobials or bacteriocides, perfumes, coloring agents and dyes may be used.
  • These optional components must be chosen so as not to interfere with the antiperspirant efficacy and the composition stability.
  • These optional components are generally present in the compositions of the present invention at a level of from about 0.01% to about 10%.
  • the present compositions are preferably in the form of a low-viscosity non-aerosol pump spray.
  • the present invention is applicable to other liquid antiperspirant product types, such as aerosol or roll-on product types.
  • Products formulated as aerosols will also comprise a propel!ant material. Any of the commonly used propellants in the antiperspirancy art are suitable.
  • Products formulated as roll-ons will also comprise a thickening agent to raise the viscosity of the composition. Suitable thickening agents include carboxymethyl cellulose, clay thickeners, colloidal silica, and Microthene* beads, manufactured by U.S.I. Chemicals, having a mean particle diameter of less than about 20 microns.
  • the antiperspirant compositions of the present invention may be manufactured using methods known in the art.
  • the antiperspirant salt is first solubilized in the monohydric alcohol solvent, and a small amount of water (no more than 5% water, by weight of the antiperspirant composition) to form a clear solution.
  • the remaining components are then added to the composition using conventional formulation methods.
  • the present invention also provides methods for treating or preventing perspiration and malodor associated with human underarm perspiration. These methods comprise applying a safe and effective amount of the liquid antiperspirant compositions of the present invention to the skin in the axillary area of a human.
  • a "safe and effective amount" as used herein is an amount which is effective in eliminating or substantially reducing the production of perspiration which ultimately generates the malodors detected through formation of pungent fatty acids, while being safe for human use at a reasonable risk/benefit ratio.
  • liquid antiperspirant compositions of the present invention provide excellent cosmetic attributes both on application and throughout use. They are non-sticky, non-greasy, and quick drying. The compositions stain clothing less than other liquid spray-on antiperspirant compositions. In addition, the present compositions leave no white, chalky residue on skin upon dry down.
  • All parts, percentages, and ratios herein are by weight unless otherwise specified.
  • Example I The following is a clear, liquid, spray-on antiperspirant composition representative of the present invention.
  • Component Weight % is a clear, liquid, spray-on antiperspirant composition representative of the present invention.
  • composition is prepared as follows.
  • An aluminum sesquichlorohydrate (ASQCH) premix is prepared by combining the ASQCH, about 2/3 of the ethanol and the DRO water.
  • the main mix is then prepared by adding to the ASQCH premix the remaining ethanol, the D4 cyclomethicone, the C 12 -C 15 alcohols benzoate, the PPG-3 myristyl ether, the phenyl dimethicone, the dimethicone fluid, the Steareth-20, and the perfume, in that order.
  • the resulting antiperspirant composition provides excellent antiperspirancy efficacy with good product aesthetics and in-use characteristics.
  • the composition also remains stable over time and broad ranges of physical conditions, especially ambient temperatures.
  • Example II The following is a clear liquid spray-on antiperspirant composition representative of the present invention.
  • Total-100.0 This composition is prepared as follows.
  • the aluminum sesquichlorohydrate (ASQCH) premix is prepared by combining the ASQCH, ethanol and water.
  • the main mix is then prepared by adding to the ASQCH premix the remaining ethanol, the Ceteth-10, the Ceteth-20, the PPG-15 stearyl ether, the isopropyl myristate, the phenethyl pentamethyl disiloxane, and the D4 cyclomethicone, in that order.
  • the resulting antiperspirant composition provides excellent antiperspirancy efficacy with good product aesthetics and in-use characteristics.
  • the composition also remains stable over time and broad ranges of physical conditions, especially ambient temperatures.
  • Example HI The following is a clear liquid spray-on antiperspirant composition representative of the present invention.
  • composition is prepared as follows.
  • the aluminum sesquichlorohydrate (ASQCH) premix is prepared by combining the
  • the main mix is then prepared by adding to the ASQCH premix the remaining ethanol, the Ceteth-10, the Ceteth-20, the PPG-3 myristyl ether, the C 12 -C 15 alcohols benzoate, the perfume, the phenyl dimethicone, the dimethicone fluid, and the D4 cyclomethicone, in that order.
  • the resulting antiperspirant composition provides excellent antiperspirancy efficacy with good product aesthetics and in-use characteristics.
  • the composition also remains stable over time and broad ranges of physical conditions, especially ambient temperatures.
  • Example IV The following is a liquid antiperspirant composition representative of the present invention.
  • the aluminum sesquichlorohydrate (ASQCH) premix is prepared by combining the ASQCH, ethanol and water.
  • the main mix is then prepared by adding to the ASQCH premix the remaining ethanol, the Steareth-20, the PPG-3 myristyl ether, the C 12 -C 15 alcohols benzoate, the perfume, the phenyl dimethicone, the dimethicone fluid, and the D4 cyclomethicone, in that order.
  • the resulting antiperspirant composition provides excellent antiperspirancy efficacy with good product aesthetics and in-use characteristics.
  • the composition also remains stable over time and broad ranges of physical conditions, especially ambient temperatures.
  • Example V The following is a liquid antiperspirant composition representative of the present invention.
  • This composition is prepared as follows.
  • the aluminum sesquichlorohydrate (ASQCH) premix is prepared by combining the ASQCH, ethanol and water.
  • the main mix is then prepared by adding to the ASQCH premix the remaining ethanol, the Ceteth-10, the Ceteth-20, the Barquat MB-80®, the PPG-3 myristyl ether, the C 12 -C 15 alcohols benzoate, the phenethyl pentamethyl disiloxane, and the D4 cyclomethicone, in that order.
  • the resulting antiperspirant composition provides excellent antiperspi ancy efficacy with good product aesthetics and in-use characteristics.
  • the composition also remains stable over time and broad ranges of physical conditions, especially ambient temperatures.
  • This composition is prepared as follows.
  • the ASQCH premix is prepared by combining the ASQCH, ethanol and water.
  • the main mix is then prepared by adding to the ASQCH premix the remaining ethanol, the Steareth-20, the PPG-3 myristyl ether, the C 12 -C 15 alcohols benzoate, the fragrance, dimethicone fluid, and the D4 cyclomethicone, in that order.
  • the resulting antiperspirant composition provides excellent antiperspirancy efficacy with good product aesthetics and in-use characteristics.
  • the composition also remains stable over time and broad ranges of physical conditions, especially ambient temperatures.
  • This composition is prepared as follows.
  • the ASQCH premix is prepared by combining the ASQCH, ethanol and water.
  • the main mix is then prepared by adding to the ASQCH premix the remaining ethanol, the Steareth-20, the PPG-3 myristyl ether, the C 12 -C 15 alcohols benzoate, the fragrance, the dimethicone fluid, and the D4 cyclomethicone, in that order.
  • the resulting antiperspirant composition provides excellent antiperspirancy efficacy with good product aesthetics and in-use characteristics.
  • the composition also remains stable over time and broad ranges of physical conditions, especially ambient temperatures.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne des compositions liquides pulvérisables claires anti-transpiration ayant des viscosités inférieures à environ 15 centistokes, comprenant: un sel anti-transpiration soluble, et restant soluble, dans un solvant d'alcool monohyrdrique; des niveaux élevés (30 % ou plus) d'esters émollients et de matières de silicone, ayant des viscosités comprises entre environ 0,65 centistokes et environ 50 centistokes, ainsi que des paramètres de solubilité compris entre environ 4 et environ 10; un solubilisant de tension-actif sélectionné dans le groupe composé de tension-actifs non-ioniques éthoxylés ou propoxylés dont le HLB est compris entre environ 5 et environ 18, ainsi que des mélanges de ceux-ci, de manière que le HLB moyen du solubilisant est compris entre environ 8 et environ 14; ainsi que des niveaux relativement faibles (inférieurs à environ 50 %) d'un solvant d'alcool monohydrique, dans lequel les compositions anti-transpiration ne comprennent pas plus d'environ 5 % d'eau. Ces compositions anti-transpiration possèdent excellentes propriétés d'anti-transpiration et cosmétique à l'usage. Elles sont non collantes, non grasses, et elles sèchent rapidement. Elles tâchent les vêtements moins que d'autres anti-transpirants liquides pulvérisés. Ces compositions s'appliquent à la peau sous forme d'une pulvérisation claire et elles ne laissent aucun reste blanc, crayeux, sur la peau lorsqu'elles sèchent. Ces compositions anti-transpiration restent également stables dans le temps et dans une large variété d'états physiques, notamment à des températures ambiantes.
PCT/US1991/002687 1990-05-30 1991-04-22 Compositions liquides anti-transpiration WO1991018587A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
BR919106483A BR9106483A (pt) 1990-05-30 1991-04-22 Composicoes antiperspirante liquidas
FI925230A FI925230A0 (fi) 1990-05-30 1992-11-18 Antiperspirant sammansaettningar i vaetskeform

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53067190A 1990-05-30 1990-05-30
US530,671 1990-05-30

Publications (1)

Publication Number Publication Date
WO1991018587A1 true WO1991018587A1 (fr) 1991-12-12

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ID=24114512

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1991/002687 WO1991018587A1 (fr) 1990-05-30 1991-04-22 Compositions liquides anti-transpiration

Country Status (9)

Country Link
EP (1) EP0531337A4 (fr)
AU (1) AU7864991A (fr)
BR (1) BR9106483A (fr)
CA (1) CA2082813A1 (fr)
FI (1) FI925230A0 (fr)
IE (1) IE911838A1 (fr)
NZ (1) NZ238310A (fr)
TR (1) TR25791A (fr)
WO (1) WO1991018587A1 (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993001793A1 (fr) * 1991-07-18 1993-02-04 The Procter & Gamble Company Compositions deodorantes liquides
US5486566A (en) * 1994-09-23 1996-01-23 Dow Corning Corporation Siloxane gels
GB2314021A (en) * 1996-06-14 1997-12-17 Unilever Plc Skin cooling anti-perspirant aerosol compositions
WO2000009083A1 (fr) * 1998-08-14 2000-02-24 L'oreal S.A. Compositions de nettoyage stables contenant des agents reactifs
EP1305000A1 (fr) * 2000-08-03 2003-05-02 Unilever Plc Produits antisudorifiques et deodorants et leurs procedes d'utilisation
WO2007017119A2 (fr) * 2005-08-10 2007-02-15 Unilever Plc Compositions antitranspirantes
WO2016092052A1 (fr) * 2014-12-10 2016-06-16 L'oreal Composition anhydre sous forme d'aérosol comprenant un agent actif antitranspirant et un polymère éthylénique filmogène insoluble dans l'eau et une phényl-silicone
WO2016150671A1 (fr) * 2015-03-26 2016-09-29 Henkel Ag & Co. Kgaa Préparations cosmétiques ayant une faible adhérence sur les textiles
US10350149B2 (en) 2013-12-19 2019-07-16 L'oreal Anhydrous antiperspirant composition in aerosol form comprising an antiperspirant active agent and a water-insoluble film-forming block ethylenic polymer

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5480637A (en) 1994-10-17 1996-01-02 Dow Corning Corporation Alkylmethylsiloxane containing gels

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4732754A (en) * 1984-03-21 1988-03-22 American Cyanamid Company Method for the preparation of antiperspirant compositions having enhanced efficacy

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OA05359A (fr) * 1975-08-15 1981-02-28 Unilever Nv Composition cosmétique pour la peau.
US4435382A (en) * 1980-07-14 1984-03-06 Bristol-Myers Company Anhydrous alcoholic antiperspirant suspension composition containing certain aluminum or aluminum/zirconium salt glycine complexes
US4944937A (en) * 1984-12-19 1990-07-31 The Procter & Gamble Company Cosmetic sticks
ATE70179T1 (de) * 1986-12-23 1991-12-15 Unilever Nv Schweisshemmendes mittel.
GB8630723D0 (en) * 1986-12-23 1987-02-04 Unilever Plc Cosmetic product
EP0404532A1 (fr) * 1989-06-23 1990-12-27 The Procter & Gamble Company Compositions antiperspirantes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4732754A (en) * 1984-03-21 1988-03-22 American Cyanamid Company Method for the preparation of antiperspirant compositions having enhanced efficacy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP0531337A4 *

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993001793A1 (fr) * 1991-07-18 1993-02-04 The Procter & Gamble Company Compositions deodorantes liquides
US5409694A (en) * 1991-07-18 1995-04-25 Procter & Gamble Liquid deodorant compositions
US5486566A (en) * 1994-09-23 1996-01-23 Dow Corning Corporation Siloxane gels
GB2314021A (en) * 1996-06-14 1997-12-17 Unilever Plc Skin cooling anti-perspirant aerosol compositions
WO2000009083A1 (fr) * 1998-08-14 2000-02-24 L'oreal S.A. Compositions de nettoyage stables contenant des agents reactifs
EP1305000A1 (fr) * 2000-08-03 2003-05-02 Unilever Plc Produits antisudorifiques et deodorants et leurs procedes d'utilisation
JP2009504583A (ja) * 2005-08-10 2009-02-05 ユニリーバー・ナームローゼ・ベンノートシヤープ 制汗剤組成物類
WO2007017119A3 (fr) * 2005-08-10 2007-05-18 Unilever Plc Compositions antitranspirantes
WO2007017119A2 (fr) * 2005-08-10 2007-02-15 Unilever Plc Compositions antitranspirantes
AU2006278898B2 (en) * 2005-08-10 2009-05-14 Unilever Global Ip Limited Antiperspirant compositions
AU2006278898B8 (en) * 2005-08-10 2009-06-11 Unilever Global Ip Limited Antiperspirant compositions
CN101277673B (zh) * 2005-08-10 2011-06-08 荷兰联合利华有限公司 止汗组合物
US10350149B2 (en) 2013-12-19 2019-07-16 L'oreal Anhydrous antiperspirant composition in aerosol form comprising an antiperspirant active agent and a water-insoluble film-forming block ethylenic polymer
WO2016092052A1 (fr) * 2014-12-10 2016-06-16 L'oreal Composition anhydre sous forme d'aérosol comprenant un agent actif antitranspirant et un polymère éthylénique filmogène insoluble dans l'eau et une phényl-silicone
FR3029776A1 (fr) * 2014-12-10 2016-06-17 Oreal Composition anhydre sous forme d'aerosol comprenant un actif anti-transpirant, un polymere ethylenique filmogene non hydrosoluble et sequence et une silicone phenylee
US20170360658A1 (en) * 2014-12-10 2017-12-21 L'oreal Anhydrous composition in aerosol form comprising an antiperspirant active agent and a water-insoluble film-forming block ethylenic polymer and a phenyl silicone
US10993892B2 (en) 2014-12-10 2021-05-04 L'oreal Anhydrous composition in aerosol form comprising an antiperspirant active agent and a water-insoluble film-forming block ethylenic polymer and a phenyl silicone
WO2016150671A1 (fr) * 2015-03-26 2016-09-29 Henkel Ag & Co. Kgaa Préparations cosmétiques ayant une faible adhérence sur les textiles

Also Published As

Publication number Publication date
EP0531337A4 (en) 1993-04-14
TR25791A (tr) 1993-09-01
CA2082813A1 (fr) 1991-12-01
IE911838A1 (en) 1991-12-04
FI925230A (fi) 1992-11-18
FI925230A0 (fi) 1992-11-18
AU7864991A (en) 1991-12-31
BR9106483A (pt) 1993-05-25
NZ238310A (en) 1993-05-26
EP0531337A1 (fr) 1993-03-17

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