WO1991009961A3 - Nouveaux produits - Google Patents
Nouveaux produits Download PDFInfo
- Publication number
- WO1991009961A3 WO1991009961A3 PCT/GB1990/001997 GB9001997W WO9109961A3 WO 1991009961 A3 WO1991009961 A3 WO 1991009961A3 GB 9001997 W GB9001997 W GB 9001997W WO 9109961 A3 WO9109961 A3 WO 9109961A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- novel products
- paraherquamide
- imi
- oxides
- preparing
- Prior art date
Links
- UVZZDDLIOJPDKX-ITKQZBBDSA-N paraherquamide Chemical compound O1C(C)(C)C=COC2=C1C=CC1=C2NC(=O)[C@]11C(C)(C)[C@@H]2C[C@]3(N(C4)CC[C@@]3(C)O)C(=O)N(C)[C@]42C1 UVZZDDLIOJPDKX-ITKQZBBDSA-N 0.000 abstract 2
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- 241000228168 Penicillium sp. Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 229930188716 paraherquamide Natural products 0.000 abstract 1
- UVZZDDLIOJPDKX-UHFFFAOYSA-N paraherquamide A Natural products O1C(C)(C)C=COC2=C1C=CC1=C2NC(=O)C11C(C)(C)C2CC3(N(C4)CCC3(C)O)C(=O)N(C)C42C1 UVZZDDLIOJPDKX-UHFFFAOYSA-N 0.000 abstract 1
- 238000010189 synthetic method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/80—Penicillium
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Botany (AREA)
- Mycology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898928844A GB8928844D0 (en) | 1989-12-21 | 1989-12-21 | Novel compounds |
GB8928844.3 | 1989-12-21 | ||
GB909024716A GB9024716D0 (en) | 1990-11-14 | 1990-11-14 | Novel products |
GB9024716.4 | 1990-11-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1991009961A2 WO1991009961A2 (fr) | 1991-07-11 |
WO1991009961A3 true WO1991009961A3 (fr) | 1991-10-31 |
Family
ID=26296401
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1990/001997 WO1991009961A2 (fr) | 1989-12-21 | 1990-12-20 | Nouveaux produits |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0506814A1 (fr) |
JP (1) | JPH05502163A (fr) |
CA (1) | CA2071982A1 (fr) |
IE (1) | IE904606A1 (fr) |
PT (1) | PT96298A (fr) |
WO (1) | WO1991009961A2 (fr) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3134936B2 (ja) * | 1992-10-16 | 2001-02-13 | 沖電気工業株式会社 | 衝撃センサ |
TW410227B (en) * | 1993-06-16 | 2000-11-01 | Upjohn Co | 14-substituted marcfortines and derivatives useful as antiparasitic agents |
TW334436B (en) * | 1995-07-21 | 1998-06-21 | Upjohn Co | Antiparasitic marcfortines and paraherquamides |
ZA976761B (en) * | 1996-09-09 | 1999-01-29 | Upjohn Co | 25 Methylene and 24,25-epoxy marcfortines and paraherquamides |
WO1998021211A1 (fr) * | 1996-11-15 | 1998-05-22 | Pharmacia & Upjohn Company | Marcfortines et paraherquamides substitues en position 1 et 2 utilises comme antiparasitaires |
MX2011005011A (es) | 2008-11-14 | 2011-07-29 | Merial Ltd | Compuestos de arilazol-2-il-cianoetilamino enantiomericamente enriquecidos, metodo de elaboracion y de uso de los mismos. |
PL396375A1 (pl) | 2008-11-19 | 2012-04-23 | Merial Limited | Kompozycje obejmujące arylopirazol i/lub formamidynę, sposoby i zastosowania je obejmujące |
EP2376513B1 (fr) | 2008-12-04 | 2015-02-25 | Merial Limited | Dérivés dimères d'avermectine et de milbémycine |
CA2782902C (fr) | 2009-12-04 | 2017-10-17 | Merial Limited | Composes pesticides bis-organosulfures |
BR112012014921B1 (pt) | 2009-12-17 | 2020-11-03 | Merial, Inc. | compostos dihidroazol parasiticidas e composições compreendendo os mesmos |
MX2012006921A (es) | 2009-12-17 | 2012-07-10 | Merial Ltd | Composiciones que comprenden compuestos de lactona macrociclica y espirodioxepinoindoles. |
UA108641C2 (uk) | 2010-04-02 | 2015-05-25 | Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування | |
LT2640728T (lt) | 2010-11-16 | 2017-03-27 | Merial, Inc. | Nauji monenzino dariniai, skirti pirmuonių sukeltų infekcijų gydymui |
US20120329832A1 (en) | 2011-06-27 | 2012-12-27 | Jean Delaveau | Novel Insect-Repellent Coumarin Derivatives, Syntheses, and Methods of Use |
ES2618813T3 (es) | 2011-06-27 | 2017-06-22 | Merial, Inc. | Compuestos y composiciones de éter amido-piridílico y uso contra los parásitos |
EP3788874A1 (fr) | 2011-09-12 | 2021-03-10 | Boehringer Ingelheim Animal Health USA Inc. | Compositions parasiticides comprenant un agent actif d'isoxazoline, procédés et utilisations associés |
WO2013044118A2 (fr) | 2011-09-23 | 2013-03-28 | Merial Limited | Modélisation indirecte de molécules répulsives inédites actives contre les insectes, les acariens et autres arthropodes |
WO2013074892A1 (fr) | 2011-11-17 | 2013-05-23 | Merial Limited | Compositions comprenant un aryl pyrazole et un imidazole substitué, procédés et utilisations de celles-ci |
EP3351546B9 (fr) | 2011-12-02 | 2024-07-10 | Boehringer Ingelheim Vetmedica GmbH | Formulations de moxidectine injectables à action prolongée |
GB2514951C (en) | 2012-02-06 | 2020-11-04 | Boehringer Ingelheim Animal Health Usa Inc | Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof |
JO3626B1 (ar) | 2012-02-23 | 2020-08-27 | Merial Inc | تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها |
PT2895465T (pt) | 2012-04-20 | 2019-01-16 | Boehringer Ingelheim Animal Health Usa Inc | Composições parasiticidas compreendendo derivados de benzimidazoles, os seus métodos e as suas utilizações |
NZ723198A (en) | 2012-11-20 | 2018-11-30 | Boehringer Ingelheim Animal Health Usa Inc | Anthelmintic compounds and compositions and methods of using thereof |
PT3063144T (pt) | 2013-11-01 | 2021-10-28 | Boehringer Ingelheim Animal Health Usa Inc | Compostos de isoxazolina antiparasitários e pesticidas |
JP6682719B2 (ja) | 2014-04-17 | 2020-04-15 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 寄生生物から動物を保護するためのマロノニトリル化合物の使用 |
MX361606B (es) | 2014-05-19 | 2018-12-11 | Merial Inc | Compuestos antihelmínticos. |
AU2015276941B2 (en) | 2014-06-19 | 2018-07-19 | Boehringer Ingelheim Animal Health USA Inc. | Parasiticidal compositions comprising indole derivatives, methods and uses thereof |
NZ731446A (en) | 2014-10-31 | 2018-09-28 | Boehringer Ingelheim Animal Health Usa Inc | Parasiticidal composition comprising fipronil |
UY36570A (es) | 2015-02-26 | 2016-10-31 | Merial Inc | Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas |
KR20180002886A (ko) | 2015-05-20 | 2018-01-08 | 메리얼 인코포레이티드 | 구충성 뎁시펩티드 화합물 |
UY37137A (es) | 2016-02-24 | 2017-09-29 | Merial Inc | Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos |
WO2018039508A1 (fr) | 2016-08-25 | 2018-03-01 | Merial, Inc. | Procédé de réduction d'effets indésirables dans des traitements antiparasitaires |
CN110381738B (zh) | 2016-10-14 | 2021-07-16 | 勃林格殷格翰动物保健美国公司 | 农药的和杀寄生物的乙烯基异噁唑啉化合物 |
US11382949B2 (en) | 2016-11-16 | 2022-07-12 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic depsipeptide compounds |
CN111194316A (zh) | 2017-08-14 | 2020-05-22 | 勃林格殷格翰动物保健美国公司 | 农药的和杀寄生物的吡唑-异噁唑啉化合物 |
EP3749096A1 (fr) | 2018-02-08 | 2020-12-16 | Boehringer Ingelheim Animal Health USA Inc. | Compositions parasiticides comprenant de l'éprinomectine et du praziquantel, procédés et utilisations associés |
MX2021000293A (es) | 2018-07-09 | 2021-07-15 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos heterociclicos antihelminticos. |
EP3883648A1 (fr) | 2018-11-20 | 2021-09-29 | Boehringer Ingelheim Animal Health USA Inc. | Composé indazolylcyanoéthylamino, compositions associées, procédé de fabrication et procédés d'utilisation de celui-ci |
BR112021016196A2 (pt) | 2019-03-01 | 2021-10-05 | Boehringer Ingelheim Animal Health USA Inc. | Composições injetáveis de clorsulon, métodos e usos das mesmas |
WO2020191091A1 (fr) | 2019-03-19 | 2020-09-24 | Boehringer Ingelheim Animal Health USA Inc. | Composés d'aza-benzothiophène et d'aza-benzofurane anthelminthiques |
AU2021278889A1 (en) | 2020-05-29 | 2023-02-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Anthelmintic heterocyclic compounds |
AU2021410052B2 (en) | 2020-12-21 | 2025-01-09 | Boehringer Ingelheim Vetmedica Gmbh | Parasiticidal collar comprising isoxazoline compounds |
JP2025507585A (ja) | 2022-02-17 | 2025-03-21 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー | 流体製品メーラーを提供する方法及びシステム |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0301742A2 (fr) * | 1987-07-28 | 1989-02-01 | Merck & Co. Inc. | Paraherquamide et dihydroparaherquamide comme agents antiparasitaires |
EP0322937A2 (fr) * | 1987-11-27 | 1989-07-05 | Merck & Co. Inc. | Dérivés de la paraherquamide isolés à partir d'un bouillon de fermentation et actifs comme agents antiparasitaires |
US4866060A (en) * | 1988-08-19 | 1989-09-12 | Merck & Co., Inc. | Use of the natural product marcfortines as antiparasitic agents |
EP0354615A1 (fr) * | 1988-08-12 | 1990-02-14 | Merck & Co. Inc. | Dérivés synthétiques de paraherquamide |
US4923867A (en) * | 1988-08-24 | 1990-05-08 | Merck & Co., Inc. | Synthetic marcfortine derivatives useful as antiparasitic agents |
-
1990
- 1990-12-19 IE IE460690A patent/IE904606A1/en unknown
- 1990-12-20 WO PCT/GB1990/001997 patent/WO1991009961A2/fr not_active Application Discontinuation
- 1990-12-20 EP EP91901844A patent/EP0506814A1/fr not_active Withdrawn
- 1990-12-20 CA CA002071982A patent/CA2071982A1/fr not_active Abandoned
- 1990-12-20 JP JP3502104A patent/JPH05502163A/ja active Pending
- 1990-12-20 PT PT96298A patent/PT96298A/pt not_active Application Discontinuation
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0301742A2 (fr) * | 1987-07-28 | 1989-02-01 | Merck & Co. Inc. | Paraherquamide et dihydroparaherquamide comme agents antiparasitaires |
EP0322937A2 (fr) * | 1987-11-27 | 1989-07-05 | Merck & Co. Inc. | Dérivés de la paraherquamide isolés à partir d'un bouillon de fermentation et actifs comme agents antiparasitaires |
EP0354615A1 (fr) * | 1988-08-12 | 1990-02-14 | Merck & Co. Inc. | Dérivés synthétiques de paraherquamide |
US4866060A (en) * | 1988-08-19 | 1989-09-12 | Merck & Co., Inc. | Use of the natural product marcfortines as antiparasitic agents |
US4923867A (en) * | 1988-08-24 | 1990-05-08 | Merck & Co., Inc. | Synthetic marcfortine derivatives useful as antiparasitic agents |
Non-Patent Citations (2)
Title |
---|
J. Am. Chem. Soc., vol. 110, No. 17, August 1988, R.M. Williams et al: "Facial selectivity of the intramolecular SN2' cyclization: Stereocontrolled total synthesis of brevianamide B", pages 5927-5929, see compound 6 * |
J. Am. Chem. Soc., vol. 111, April 1989, R.M. Williams et al: "Remarkable, enantiodivergent biogenesis of brevianamide A and B", pages 3064-3065, see compound 7 * |
Also Published As
Publication number | Publication date |
---|---|
EP0506814A1 (fr) | 1992-10-07 |
JPH05502163A (ja) | 1993-04-22 |
WO1991009961A2 (fr) | 1991-07-11 |
CA2071982A1 (fr) | 1991-06-22 |
PT96298A (pt) | 1991-09-30 |
IE904606A1 (en) | 1991-07-03 |
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