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WO1990001697A1 - Controle de la glycemie - Google Patents

Controle de la glycemie Download PDF

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Publication number
WO1990001697A1
WO1990001697A1 PCT/GB1989/000899 GB8900899W WO9001697A1 WO 1990001697 A1 WO1990001697 A1 WO 1990001697A1 GB 8900899 W GB8900899 W GB 8900899W WO 9001697 A1 WO9001697 A1 WO 9001697A1
Authority
WO
WIPO (PCT)
Prior art keywords
waveguide
light
blood
optical waveguide
light source
Prior art date
Application number
PCT/GB1989/000899
Other languages
English (en)
Inventor
Christopher Davies
Robert Marc Clement
Original Assignee
Red Kite Technology Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Red Kite Technology Limited filed Critical Red Kite Technology Limited
Publication of WO1990001697A1 publication Critical patent/WO1990001697A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6848—Needles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G01N21/43—Refractivity; Phase-affecting properties, e.g. optical path length by measuring critical angle
    • G01N21/431—Dip refractometers, e.g. using optical fibres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose

Definitions

  • Optical fibres generally have a central core, entirely surrounded by a plastics or glass sheath (the cladding) .
  • the refractive index of the core In order for optical transmission along such a fibre to take place, the refractive index of the core must be greater than that of the cladding. It is well known that the relative index of refraction of the core and cladding will determine the transmission characteristics of light along the optical fibre.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Optics & Photonics (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Emergency Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Un appareil de contrôle de la glycémie comprend; (a) un guide d'onde de réflexion interne totale comportant une âme et un gainage réfléchissant, au moins une partie de l'âme étant dépourvue d'un tel gainage, (b) une source de lumière (telle qu'un laser) optiquement couplée à une extrémité du guide d'ondes, (c) un détecteur de lumière agencé pour produire un signal représentant la quantité de lumière transmise à partir de ladite source de lumière par le guide d'ondes au-delà de la partie non gainée, et (d) un dispositif d'administration d'insuline tel que l'insuline est administrée à un patient lorsque la quantité de lumière détectée par le détecteur varie de plus d'une valeur prédéterminée.
PCT/GB1989/000899 1988-08-05 1989-08-07 Controle de la glycemie WO1990001697A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888818690A GB8818690D0 (en) 1988-08-05 1988-08-05 Refractive index measurement
GB8818690.3 1988-08-05

Publications (1)

Publication Number Publication Date
WO1990001697A1 true WO1990001697A1 (fr) 1990-02-22

Family

ID=10641695

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1989/000899 WO1990001697A1 (fr) 1988-08-05 1989-08-07 Controle de la glycemie

Country Status (3)

Country Link
AU (1) AU4053489A (fr)
GB (1) GB8818690D0 (fr)
WO (1) WO1990001697A1 (fr)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE9110757U1 (de) * 1991-08-30 1992-02-13 Klein, Rainer, 5840 Schwerte Integriert-optischer Stoffsensor
WO1993009421A1 (fr) * 1991-11-04 1993-05-13 Novo Nordisk A/S Appareil pour la mesure ex-vivo des niveaux de sucre dans le sang
WO1999058048A1 (fr) * 1998-05-13 1999-11-18 Biosensor, Inc. Appareil et procede de mesure non invasive du taux de glycemie
FR2832505A1 (fr) * 2001-11-16 2003-05-23 Inst Francais Du Petrole Refractometre a fibre optique
US6584335B1 (en) 1997-08-09 2003-06-24 Roche Diagnostics Gmbh Analytical device for in vivo analysis in the body of a patient
DE102004055032A1 (de) * 2004-11-15 2006-08-03 Roche Diagnostics Gmbh Vorrichtung und Verfahren zur Bestimmung der Konzentration von Glukose in interstitieller Flüssigkeit
WO2006095343A1 (fr) 2005-03-10 2006-09-14 Anatoly Babchenko Capteur optique et son procédé d’utilisation
WO2007090147A3 (fr) * 2006-01-31 2008-08-07 Univ Illinois Procédé et appareil de mesure des propriétés optiques de tissus
US7586618B2 (en) 2005-02-28 2009-09-08 The Board Of Trustees Of The University Of Illinois Distinguishing non-resonant four-wave-mixing noise in coherent stokes and anti-stokes Raman scattering
US7623908B2 (en) 2003-01-24 2009-11-24 The Board Of Trustees Of The University Of Illinois Nonlinear interferometric vibrational imaging
US8983580B2 (en) 2008-01-18 2015-03-17 The Board Of Trustees Of The University Of Illinois Low-coherence interferometry and optical coherence tomography for image-guided surgical treatment of solid tumors

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1040271A (fr) * 1975-01-22 1978-10-10 Anthony M. Albisser Cellule beta artificielle
US4169676A (en) * 1976-02-20 1979-10-02 Nils Kaiser Method for determining the contents of metabolic products in the blood
DE3232059A1 (de) * 1981-09-04 1983-03-24 Westinghouse Electric Corp., 15222 Pittsburgh, Pa. Glasfaserdetektor
GB2121556A (en) * 1982-03-31 1983-12-21 Nippon Beet Sugar Mfg Determining refractive index of a liquid
US4706677A (en) * 1985-09-23 1987-11-17 Spectramed, Inc. Multiple sensor bundle
WO1988001376A1 (fr) * 1986-08-14 1988-02-25 Radiometer A/S Procede et dispositif permettant de determiner le niveau d'un analyte dans un echantillon de sang total

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1040271A (fr) * 1975-01-22 1978-10-10 Anthony M. Albisser Cellule beta artificielle
US4169676A (en) * 1976-02-20 1979-10-02 Nils Kaiser Method for determining the contents of metabolic products in the blood
DE3232059A1 (de) * 1981-09-04 1983-03-24 Westinghouse Electric Corp., 15222 Pittsburgh, Pa. Glasfaserdetektor
GB2121556A (en) * 1982-03-31 1983-12-21 Nippon Beet Sugar Mfg Determining refractive index of a liquid
US4706677A (en) * 1985-09-23 1987-11-17 Spectramed, Inc. Multiple sensor bundle
WO1988001376A1 (fr) * 1986-08-14 1988-02-25 Radiometer A/S Procede et dispositif permettant de determiner le niveau d'un analyte dans un echantillon de sang total

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JAPANESE JOURNAL OF APPLIED PHYSICS, Vol. 22, No. 12, December 1983, TAKASHI TAKEO et al., "Fluid Observation with an Optical Fiber Photorefractometer", page 1920. *
OPTICS AND LASER TECHNOLOGY, Vol. 17, No. 1, February 1985, I.N. ROSS et al., "Optical Monitoring of Glucose Concentration", pages 31-35. *

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE9110757U1 (de) * 1991-08-30 1992-02-13 Klein, Rainer, 5840 Schwerte Integriert-optischer Stoffsensor
WO1993009421A1 (fr) * 1991-11-04 1993-05-13 Novo Nordisk A/S Appareil pour la mesure ex-vivo des niveaux de sucre dans le sang
US6584335B1 (en) 1997-08-09 2003-06-24 Roche Diagnostics Gmbh Analytical device for in vivo analysis in the body of a patient
WO1999058048A1 (fr) * 1998-05-13 1999-11-18 Biosensor, Inc. Appareil et procede de mesure non invasive du taux de glycemie
FR2832505A1 (fr) * 2001-11-16 2003-05-23 Inst Francais Du Petrole Refractometre a fibre optique
US6975388B2 (en) 2001-11-16 2005-12-13 Institut Francais Du Petrole Optical-fiber refractometer
US7623908B2 (en) 2003-01-24 2009-11-24 The Board Of Trustees Of The University Of Illinois Nonlinear interferometric vibrational imaging
DE102004055032A1 (de) * 2004-11-15 2006-08-03 Roche Diagnostics Gmbh Vorrichtung und Verfahren zur Bestimmung der Konzentration von Glukose in interstitieller Flüssigkeit
DE102004055032B4 (de) * 2004-11-15 2006-12-07 Roche Diagnostics Gmbh Vorrichtung und Verfahren zur Bestimmung der Konzentration von Glukose in interstitieller Flüssigkeit
US7586618B2 (en) 2005-02-28 2009-09-08 The Board Of Trustees Of The University Of Illinois Distinguishing non-resonant four-wave-mixing noise in coherent stokes and anti-stokes Raman scattering
WO2006095343A1 (fr) 2005-03-10 2006-09-14 Anatoly Babchenko Capteur optique et son procédé d’utilisation
US8761865B2 (en) 2005-03-10 2014-06-24 Anatoly Babchenko Optical sensor and a method of its use
WO2007090147A3 (fr) * 2006-01-31 2008-08-07 Univ Illinois Procédé et appareil de mesure des propriétés optiques de tissus
US8983580B2 (en) 2008-01-18 2015-03-17 The Board Of Trustees Of The University Of Illinois Low-coherence interferometry and optical coherence tomography for image-guided surgical treatment of solid tumors
US11779219B2 (en) 2008-01-18 2023-10-10 The Board Of Trustees Of The University Of Illinois Low-coherence interferometry and optical coherence tomography for image-guided surgical treatment of solid tumors

Also Published As

Publication number Publication date
GB8818690D0 (en) 1988-09-07
AU4053489A (en) 1990-03-05

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