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WO1989009071A1 - Seringue de dosage a usage unique - Google Patents

Seringue de dosage a usage unique Download PDF

Info

Publication number
WO1989009071A1
WO1989009071A1 PCT/US1989/000577 US8900577W WO8909071A1 WO 1989009071 A1 WO1989009071 A1 WO 1989009071A1 US 8900577 W US8900577 W US 8900577W WO 8909071 A1 WO8909071 A1 WO 8909071A1
Authority
WO
WIPO (PCT)
Prior art keywords
plunger
barrel
syringe
injectate
tip
Prior art date
Application number
PCT/US1989/000577
Other languages
English (en)
Inventor
William Padilla
Fred P. Lampropoulos
Kent W. Stanger
Original Assignee
Merit Medical Systems, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merit Medical Systems, Inc. filed Critical Merit Medical Systems, Inc.
Publication of WO1989009071A1 publication Critical patent/WO1989009071A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/1018—Balloon inflating or inflation-control devices
    • A61M25/10181—Means for forcing inflation fluid into the balloon
    • A61M25/10182—Injector syringes

Definitions

  • This invention relates to disposable medical syringes. More particularly, the present invention relates to a disposable control syringe.
  • control syringes are known in the art, and are used for a variety of purposes.
  • hypodermic syringes 0.5 ml to 2 ml capacity of hypodermic syringes must be capable of providing a relatively high pressure and rapid delivery of injectate. Further, the amount of injectate as 5 well as the handling and manipulation of the syringe must be easily and precisely controllable.
  • a bolus of liquid colder than body temperature is injected into the heart by way of a catheter lumen.
  • the change in temperature of the blood after it travels through the heart is then measured using a thermistor mounted on the end of the catheter.
  • the amount of cold liquid injected into the catheter must be carefully controlled in order for the cardiac output to be measured accurately by the temperature change occurring in the blood.
  • many catheterization procedures require that a balloon located somewhere along the length of the catheter be inflated with a liquid.
  • a syringe is filled with the liquid which is injected into the catheter lumen leading to the balloon.
  • the amount of fluid must be carefully controlled and must never exceed a predetermined amount or the possibility arises that the catheter balloon may rupture with potentially serious consequences.
  • control syringes which were used in the art were fabricated from stainless steel and glass. While these kinds of syringes provided a rugged, durable construction, they also suffered from the disadvantage that they were very costly devices, they were difficult to manufacture, and there 1 was always the attendant problem of having to sterilize the devices after use, with the further possibility of contamination if sterilization was not properly carried out. 5
  • some disposable control syringes suffer from other design inadequacies such as partially occluding the plunger of the syringe so that the person using the syringe cannot view the entire length of the barrel which contains fluid to be injected.
  • Visual inspection of the barrel is an important feature since one must ascertain that no air bubbles are present, otherwise the potential danger of injecting air into a vessel may be present.
  • one object of the present invention is to provide a disposable control syringe wherein the plunger is designed so that bending is minimized throughout the plunger's movement through the syringe barrel, as well as 0 assuring that the plunger's -_cve-,ent is s_ooth and does not bind.
  • Another object of the present invention is to provide a disposable control syringe wherein a locking mechanism is 5 provided to preset and hence accurately control the maximum amount of fluid which can be injected, and which locking, mechanism can be smoothly adjusted and easily snapped into 0 P lace -
  • Still another object of the present invention is to provide a disposable control syringe which is provided with a structure which securely connects the syringe to a medical 5 device such as a catheter manifold, which prevents breakage 09071
  • Yet another object of the present invention is to provide a disposable control syringe wherein a structure is provided so that the plunger is restrained to prevent its complete removal from the syringe barrel while filling the barrel.
  • Still another object of the invention is to provide a disposable control syringe wherein essentially the entire length of the barrel of the syringe which contains fluid to be injected is visible so as to permit visual inspection of the fluid being injected.
  • Still another important object of the present invention is to provide a disposable control syringe which is provided . with appropriate structure for gripping the syringe so that application of the necessary force on the syringe plunger can be conveniently applied using any of several desired techniques, including application of force on the syringe plunger using two hands, or in the alternative, using one hand, and by application of the force using the thumb or the- palm of the hand. Additional objects and advantages of the invention will be apparent from the drawings, description and appended claims which follow, or may be learned by the practice of the invention.
  • the present invention comprises a medical control syringe which provides the advantage of being of low enough cost to be disposable after a single use, while still incorporating the desirable features and advantages of a rugged, durable syringe that can withstand the rigors required in typical applications for such syringes, as explained above.
  • the control syringe of the present invention comprises a barrel fabricated from a hard, polycarbonate plastic which is highly transparent to permit visual inspection of the fluid held within the syringe barrel. Both finger loops and wing grips are disposed on the sides of the barrel to allow the user to grasp the barrel in a variety of ways.
  • a rigid, ABS plastic plunger is positioned within the syringe barrel.
  • the leading end of the plunger is provided with a collar to space the tip of the plunger slightly forward of the grips, thus ensuring that injectate will always be forward of the point where the control syringe is grasped, and thus susceptible to visual inspection.
  • a stabilizing disc on the collar and an end cap on the barrel cooperate to provide plunger stability so as to minimize bending of the plunger while it is being pushed through the barrel.
  • the cap also prevents the plunger from being inadver- tently removed from the barrel when it is filled.
  • the plunger is provided with a releasable locking ring which may be preset to control the maximum amount of fluid which can be injected.
  • a rotatable luer connector is provided on the barrel to connect the syringe to a medical device such as a catheter manifold.
  • the connector is preferably fabricated so that the body of the syringe may be rotated without loosening the connector or damaging the syringe while it is connected to the manifold, while still providing a mechanically stable attachment to the manifold.
  • the plunger is also provided with a thumb loop having a palm rest to facilitate applying hand pressure using any of several alternative techniques.
  • Figure 1 is a perspective view of the presently preferred embodiment of the present invention.
  • Figure 2 is a cross-sectional view taken along line 2-2 of Figure 1.
  • Figure 3 is an elevational cross-sectional view of the embodiment of Figure 1, showing the plunger fully retracted.
  • Figure 3A is an enlarged portion of Figure 3.
  • Figure 4 is an exploded perspective view of th embodiment of Figure 1.
  • Figures 5A - 5C are perspective views which schematicall illustrate alternative ways of grasping the control syring of the present invention.
  • the control syringe of th present invention is generally designated at 10.
  • the contro syringe 10 is comprised of generally two main components. Th first is a barrel means for holding injectate which is to be expelled.
  • the barrel means is comprised of a barrel assembly generally designated 12.
  • the other main component of the control syringe is a plunger means which is slidably engaged within the barrel means.
  • the plunger means is comprised of a plunger assembly generally designated at 14.
  • the barrel assembly 12 is comprised of a cylindrical barrel 13 which has formed through the center of the barrel a bore 20.
  • the barrel 13 is constructed from material that is highly visually
  • the barrel assembly 12 has at its forward end a conically shaped portion 16 which terminates in a cylinder 35.
  • a conically shaped portion 16 which terminates in a cylinder 35.
  • O-ring 37 fits. O-ring 37 assures a fluid-tight seal between luer connector 30 and cylinder 35 onto which connector 30 fits. 5
  • a rotatable female luer connector 30 with central cylindrical shaft 28 is provided with an extended base 31 which snaps onto the cylinder 35. Bore 26 through the center 0 of cylinders 35, 39 and shaft 28 provides a passageway through which injectate is expelled into a catheter manifold.
  • a locking ring 45 on cylinder 35 is designed to mate with a corresponding groove formed on the inside surface of base 31. 5 -j e female luer connector 30 is adapted to rotate around cylinder 35 so as to provide a rotatable connector means for permitting rotation of the entire syringe when connected to a stationary device such as a manifold from which the fluid 0 . . can be dispensed through appropriate catheter lines into a patient.
  • control syringe of the present invention can be quickly and easily oriented by rotating the syringe so that the physician can grasp the syringe in the most convenient manner thereby optimizing the application of force and facilitating more accurate control of the fluid as it is
  • the cylinder 35 and platform 47 serve as a means for reinforcing and stabilizing the rotatable luer connector 30 when connected to a catheter manifold.
  • 35 47 provides a flat, uniform support for base 31. Since the end 16 of syringe barrel 13 is conical, without platform 47 the base 31 of luer connector 30 would not have adequate support, permitting undesired movement at the point of connection between luer connector 30 and barrel 13. Cylinder 5
  • Base 31 of luer connector 30 and reinforcing cylinder 35 are designed to
  • Rotatable female luer connector 30 is also preferably fabricated from polycarbonate plastic so as to 5 provide sufficient rigidity and strength to resist breakage and/or inadvertent disconnection of the control syringe when connected to a device such as a catheter manifold.
  • the barrel 0 assembly 12 further comprises an end cap 22 which snaps onto a lip 19 at the trailing end 18 of the syringe barrel 13.
  • variable grip means is generally designated at reference numerals 15 and 17, and is designed to permit the syringe to be grasped by a physician in any one of several different manners.
  • the variable 5 grip means comprises, for example, a pair of wing grips 36 as well as an adjacent pair of finger loops 34, and a thumb loop 38 having a flattened palm member 40. Webbing 49 strengthens the grips 36 and loops 34.
  • variable grip means 15 and 17 permit either the wing grips 36 to be used, or the finger loops 34 to be used, or a combination of the two when using both hands to apply force to the plunger, as well as providing for actuation of the plunger using the thumb or palm.
  • the syringe assembly generally designated 14 is comprised of an elongated stem 42.
  • the stem has a notched portion provided along the length thereof, with the notches being illustrated as at reference numeral 44.
  • a nut 48 is situated on the stem 42 and is used for limiting movement of the stem 42 when actuating the plunger such that a controlled amount of fluid can be expelled from the syringe depending upon placement of the nut 42 along the notched portion of the stem.
  • stem 42 is rounded and smooth so that it does not bind when moving through opening 24 of collar 23 on the end cap 22.
  • locking nut 48 is designed so that a friction fit is provided when nut 48 is on stem 42. This prevents nut 48 from sliding up and down on stem 42 and thus getting in the way when nut 48 is not in use -
  • Locking nut 48 comprises a protruding member 50 which extends inwardly so as to engage the notches 44 when the nut is rotated counter-clockwise in reference to the view of Figure 2.
  • the protruding member moves to the position illustrated at 51 (shown in dashed lines) so that the protruding member 50 slides along the slot
  • Figure 3A snaps into the notch, and is firmly held there by means of rounded protrusions 53 that are formed at the entrance to each notch.
  • markings which correspond to the volume of fluid to be expelled from the syringe barrel.
  • the markings 43 on the notched portion can conveniently indicate the selected positions along the stem 42 which would fix the position of the locking nut 48 so as to permit, for example, increments of 1 cc, up to 12 cc, to be injected.
  • corresponding markings are provided on the barrel of the syringe as indicated at reference numeral 19. Barrel markings 19 permit the amount of fluid to be injected into the patient to be carefully monitored irrespective of whether the locking nut 48 is used to limit movement of the plunger or not.
  • the leading end of the plunger assembly 14 is comprised of a tip 52 which serves as a means for establishing a fluid- tight seal within the barrel such that the injectate or fluid within the barrel will not flow past the tip 52.
  • the tip 52 is preferably formed of a rubber-like material which will provide the needed fluid-tight fit while still permitting the plunger to slide freely back and forth inside the barrel. In the illustrated embodiment, as shown best in Figure 3, the rubber tip 52 fits over a disk 51 which is provided at the end of the plunger assembly 14.
  • a cylindrical collar 56 extends from disk 64 at one end thereof to a disk 62 at the other end thereof.
  • the collar 56 serves as a means for spacing the tip
  • the dis 62 serves as a means for stabilizing the stem 42 of th 5 plunger assembly as the plunger is pushed through the barre of the syringe.
  • the entire plunger assembly 14 is fabricated from a hard plastic material such as ABS to provide further rigidity and strength to the overall 0 assembly.
  • FIG. 4 The exploded perspective view of Figure 4 serves to illustrate the preferred method of assembly of the control syringe.
  • the locking nut 48 and end cap 22 are placed onto 5 the stem 42, and collar 56 is then bonded onto the end of stem 42.
  • the rubber tip 52 is then placed over the end of disk 51 and the plunger assembly is then inserted into the barrel 13 of the syringe, and end cap 22 is shaped onto lip 19 of the 0 .
  • syringe barrel 13 O-ring 37 is placed over cylinder 39, and then luer connector 30 is snapped onto reinforcing cylinder

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Une seringue de dosage médicale à usage unique (10) comporte un cylindre (12) réalisé dans une matière plastique transparente et est pourvue d'une paire de crochets fermés (34) et d'ailettes de préhension (36) solidaires destinés à faciliter différents modes de préhension et d'application d'effort sur le piston (14). Ce dernier présente un embout hermétique élastique (52) qui est en contact d'étanchéité coulissant avec la paroi de l'alésage cylindrique du cylindre. Des premier et second disques stabilisateurs (62, 64) sont prévus sur le piston afin de le maintenir en alignement coaxial lorsqu'on le pousse à travers le cylindre. Un collier (56) ménagé sur le piston situe la pointe hermétique (52) légèrement en avant des crochets fermés (34) et des ailettes de préhension (36). La tige de piston (42) est également pourvue d'un crochet fermé (38) destiné au pouce et présentant un appui-paume (40), ainsi que d'une portion entaillée (44) disposée sur sa longueur. Un écrou de verrouillage (48) est emboîté sur la portion entaillée afin de limiter sélectivement la course du piston dans l'alésage. L'extrémité avant du cylindre de seringue est reliée à un dispositif médical (tel qu'un collecteur de cathéter) au moyen d'un connecteur de verrouillage rotatif (30) qui est monté sur le corps de manière à pouvoir tourner indépendamment de ce dernier.
PCT/US1989/000577 1988-03-25 1989-02-13 Seringue de dosage a usage unique WO1989009071A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17344788A 1988-03-25 1988-03-25
US173,447 1988-03-25

Publications (1)

Publication Number Publication Date
WO1989009071A1 true WO1989009071A1 (fr) 1989-10-05

Family

ID=22632077

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1989/000577 WO1989009071A1 (fr) 1988-03-25 1989-02-13 Seringue de dosage a usage unique

Country Status (2)

Country Link
AU (1) AU3432789A (fr)
WO (1) WO1989009071A1 (fr)

Cited By (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5168757A (en) * 1990-05-15 1992-12-08 Ryder International Corporation Fluid displacement and pressurizing device
US5385558A (en) * 1993-09-03 1995-01-31 Maxxim Medical, Inc. Angiographic control syringe
WO1995019196A1 (fr) * 1994-01-18 1995-07-20 Allergan Adaptateur pour collerette de seringue et procede associe
US5634910A (en) * 1995-09-22 1997-06-03 Ryder International Corporation Syringe instrument
WO1998056440A1 (fr) * 1997-06-13 1998-12-17 Percusurge, Inc. Seringue et procede servant a gonfler un ballonnet de catheter de faible volume
FR2787999A1 (fr) * 1999-01-04 2000-07-07 Yves Raphael Winckler Seringue avec embout luer lock femelle
US6234996B1 (en) 1999-06-23 2001-05-22 Percusurge, Inc. Integrated inflation/deflation device and method
US6808513B2 (en) * 1992-08-17 2004-10-26 Medrad, Inc. Front loading medical injector and syringe for use therewith
US6958053B1 (en) 1999-11-24 2005-10-25 Medrad, Inc. Injector providing drive member advancement and engagement with syringe plunger, and method of connecting a syringe to an injector
US7419478B1 (en) 2003-06-25 2008-09-02 Medrad, Inc. Front-loading syringe for medical injector having a flexible syringe retaining ring
US7540856B2 (en) 2000-02-07 2009-06-02 Medrad, Inc. Front-loading medical injector adapted to releasably engage a syringe regardless of the orientation of the syringe with respect to the injector
US7553294B2 (en) 2002-05-30 2009-06-30 Medrad, Inc. Syringe plunger sensing mechanism for a medical injector
WO2013149032A1 (fr) * 2012-03-29 2013-10-03 Biogen Idec Ma Inc. Dispositif d'administration et ses composants
EP2700426A1 (fr) * 2012-08-20 2014-02-26 Transcoject GmbH Seringue avec douille filetée rotative
US9108047B2 (en) 2010-06-04 2015-08-18 Bayer Medical Care Inc. System and method for planning and monitoring multi-dose radiopharmaceutical usage on radiopharmaceutical injectors
USD751705S1 (en) 2013-10-02 2016-03-15 Biogen Ma Inc. Syringe
US9480797B1 (en) 2015-10-28 2016-11-01 Bayer Healthcare Llc System and method for syringe plunger engagement with an injector
US9694131B2 (en) 2003-11-25 2017-07-04 Bayer Healthcare Llc Medical injector system
US9744305B2 (en) 2012-09-28 2017-08-29 Bayer Healthcare Llc Quick release plunger
CN107457161A (zh) * 2017-09-18 2017-12-12 湖北云万光电子科技有限公司 一种连接器线缆点胶装置
US9844622B2 (en) 2000-07-10 2017-12-19 Bayer Healthcare Llc Syringes for medical injector systems
US9855390B2 (en) 2006-03-15 2018-01-02 Bayer Healthcare Llc Plunger covers and plungers for use in syringes
USD847985S1 (en) 2007-03-14 2019-05-07 Bayer Healthcare Llc Syringe plunger cover
US10806852B2 (en) 2014-03-19 2020-10-20 Bayer Healthcare Llc System for syringe engagement to an injector
US11191903B2 (en) 2014-04-14 2021-12-07 Swedish Orphan Biovitrum Ab (Publ) Syringe plunger rod
USD942005S1 (en) 2007-03-14 2022-01-25 Bayer Healthcare Llc Orange syringe plunger cover
USD1002840S1 (en) 2007-03-14 2023-10-24 Bayer Healthcare Llc Syringe plunger
US11883636B2 (en) 2018-02-27 2024-01-30 Bayer Healthcare Llc Syringe plunger engagement mechanism
US11969582B2 (en) 2017-01-06 2024-04-30 Bayer Healthcare Llc Syringe plunger with dynamic seal
US11998718B2 (en) 2020-06-18 2024-06-04 Bayer Healthcare Llc System and method for syringe plunger engagement with an injector
USD1031029S1 (en) 2003-11-25 2024-06-11 Bayer Healthcare Llc Syringe plunger

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2656836A (en) * 1950-09-26 1953-10-27 Bishop & Co Platinum Works J Hypodermic syringe
US3491757A (en) * 1966-12-30 1970-01-27 Raul Olvera Arce Hypodermic syringe with non-turning tip connector
US4254773A (en) * 1978-11-24 1981-03-10 Medex Inc. Swivel coupling for a catheterization system

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2656836A (en) * 1950-09-26 1953-10-27 Bishop & Co Platinum Works J Hypodermic syringe
US3491757A (en) * 1966-12-30 1970-01-27 Raul Olvera Arce Hypodermic syringe with non-turning tip connector
US4254773A (en) * 1978-11-24 1981-03-10 Medex Inc. Swivel coupling for a catheterization system

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Product brochure of COEUR Laboratories Inc., published prior to priority date although exact date unknown, see the entire document. *
Product brochure of FMP for Control Ease Syringe, published prior to priority date although exact date unknown, see the entire document. *

Cited By (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5168757A (en) * 1990-05-15 1992-12-08 Ryder International Corporation Fluid displacement and pressurizing device
US6808513B2 (en) * 1992-08-17 2004-10-26 Medrad, Inc. Front loading medical injector and syringe for use therewith
US7081105B2 (en) 1992-08-17 2006-07-25 Medrad, Inc. Injector system having a front loading pressure jacket assembly
US5385558A (en) * 1993-09-03 1995-01-31 Maxxim Medical, Inc. Angiographic control syringe
WO1995019196A1 (fr) * 1994-01-18 1995-07-20 Allergan Adaptateur pour collerette de seringue et procede associe
US5554133A (en) * 1994-01-18 1996-09-10 Allergan, Inc. Syringe flange adapter and method
US5634910A (en) * 1995-09-22 1997-06-03 Ryder International Corporation Syringe instrument
WO1998056440A1 (fr) * 1997-06-13 1998-12-17 Percusurge, Inc. Seringue et procede servant a gonfler un ballonnet de catheter de faible volume
FR2787999A1 (fr) * 1999-01-04 2000-07-07 Yves Raphael Winckler Seringue avec embout luer lock femelle
US6234996B1 (en) 1999-06-23 2001-05-22 Percusurge, Inc. Integrated inflation/deflation device and method
US6958053B1 (en) 1999-11-24 2005-10-25 Medrad, Inc. Injector providing drive member advancement and engagement with syringe plunger, and method of connecting a syringe to an injector
US7029459B2 (en) 1999-11-24 2006-04-18 Medrad, Inc. Injector system including a powered loading device for connecting a syringe to an injector
US7465290B2 (en) 1999-11-24 2008-12-16 Medrad, Inc. Injector system including an injector drive member that automatically advances and engages a syringe plunger
US7540856B2 (en) 2000-02-07 2009-06-02 Medrad, Inc. Front-loading medical injector adapted to releasably engage a syringe regardless of the orientation of the syringe with respect to the injector
US9636452B2 (en) 2000-02-07 2017-05-02 Bayer Healthcare Llc Front-loading medical injector adapted to releasably engage a syringe regardless of the orientation of the syringe with respect to the injector
US9844622B2 (en) 2000-07-10 2017-12-19 Bayer Healthcare Llc Syringes for medical injector systems
US7553294B2 (en) 2002-05-30 2009-06-30 Medrad, Inc. Syringe plunger sensing mechanism for a medical injector
US7419478B1 (en) 2003-06-25 2008-09-02 Medrad, Inc. Front-loading syringe for medical injector having a flexible syringe retaining ring
US9694131B2 (en) 2003-11-25 2017-07-04 Bayer Healthcare Llc Medical injector system
US10894124B2 (en) 2003-11-25 2021-01-19 Bayer Healthcare Llc Medical injector system
US11596735B2 (en) 2003-11-25 2023-03-07 Bayer Healthcare Llc Medical injector system
US10434249B2 (en) 2003-11-25 2019-10-08 Bayer Healthcare Llc Medical injector system
USD1031029S1 (en) 2003-11-25 2024-06-11 Bayer Healthcare Llc Syringe plunger
US9855390B2 (en) 2006-03-15 2018-01-02 Bayer Healthcare Llc Plunger covers and plungers for use in syringes
US10668221B2 (en) 2006-03-15 2020-06-02 Bayer Healthcare Llc Plunger covers and plungers for use in syringes
USD1002840S1 (en) 2007-03-14 2023-10-24 Bayer Healthcare Llc Syringe plunger
USD942005S1 (en) 2007-03-14 2022-01-25 Bayer Healthcare Llc Orange syringe plunger cover
USD1030051S1 (en) 2007-03-14 2024-06-04 Bayer Healthcare Llc Syringe plunger
USD847985S1 (en) 2007-03-14 2019-05-07 Bayer Healthcare Llc Syringe plunger cover
USD1030052S1 (en) 2007-03-14 2024-06-04 Bayer Healthcare Llc Syringe plunger
US9108047B2 (en) 2010-06-04 2015-08-18 Bayer Medical Care Inc. System and method for planning and monitoring multi-dose radiopharmaceutical usage on radiopharmaceutical injectors
US9463335B2 (en) 2010-06-04 2016-10-11 Bayer Healthcare Llc System and method for planning and monitoring multi-dose radiopharmaceutical usage on radiopharmaceutical injectors
WO2013149032A1 (fr) * 2012-03-29 2013-10-03 Biogen Idec Ma Inc. Dispositif d'administration et ses composants
EP2700426A1 (fr) * 2012-08-20 2014-02-26 Transcoject GmbH Seringue avec douille filetée rotative
US9033937B2 (en) 2012-08-20 2015-05-19 Transcoject Gmbh Syringe
US10286152B2 (en) 2012-09-28 2019-05-14 Bayer Healthcare Llc Quick release plunger
US9744305B2 (en) 2012-09-28 2017-08-29 Bayer Healthcare Llc Quick release plunger
USD751705S1 (en) 2013-10-02 2016-03-15 Biogen Ma Inc. Syringe
US10806852B2 (en) 2014-03-19 2020-10-20 Bayer Healthcare Llc System for syringe engagement to an injector
US11103637B2 (en) 2014-03-19 2021-08-31 Bayer Healthcare Llc System for syringe engagement to an injector
US11383029B2 (en) 2014-03-19 2022-07-12 Bayer Healthcare Llc System for syringe engagement to an injector
US11191903B2 (en) 2014-04-14 2021-12-07 Swedish Orphan Biovitrum Ab (Publ) Syringe plunger rod
US11547794B2 (en) 2015-10-28 2023-01-10 Bayer Healthcare Llc System and method for syringe plunger engagement with an injector
US10512721B2 (en) 2015-10-28 2019-12-24 Bayer Healthcare Llc System and method for syringe plunger engagement with an injector
US9480797B1 (en) 2015-10-28 2016-11-01 Bayer Healthcare Llc System and method for syringe plunger engagement with an injector
US12102793B2 (en) 2015-10-28 2024-10-01 Bayer Healthcare Llc System and method for syringe plunger engagement with an injector
US11969582B2 (en) 2017-01-06 2024-04-30 Bayer Healthcare Llc Syringe plunger with dynamic seal
CN107457161A (zh) * 2017-09-18 2017-12-12 湖北云万光电子科技有限公司 一种连接器线缆点胶装置
US11883636B2 (en) 2018-02-27 2024-01-30 Bayer Healthcare Llc Syringe plunger engagement mechanism
US11998718B2 (en) 2020-06-18 2024-06-04 Bayer Healthcare Llc System and method for syringe plunger engagement with an injector

Also Published As

Publication number Publication date
AU3432789A (en) 1989-10-16

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