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WO1989008264A1 - Procede d'analyse automatique entierement selective du sang ou des composants du sang - Google Patents

Procede d'analyse automatique entierement selective du sang ou des composants du sang Download PDF

Info

Publication number
WO1989008264A1
WO1989008264A1 PCT/EP1989/000213 EP8900213W WO8908264A1 WO 1989008264 A1 WO1989008264 A1 WO 1989008264A1 EP 8900213 W EP8900213 W EP 8900213W WO 8908264 A1 WO8908264 A1 WO 8908264A1
Authority
WO
WIPO (PCT)
Prior art keywords
blood
code carrier
electronic code
electronic
tube
Prior art date
Application number
PCT/EP1989/000213
Other languages
German (de)
English (en)
Inventor
Uwe W. Ballies
Original Assignee
Ballies Uwe W
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ballies Uwe W filed Critical Ballies Uwe W
Publication of WO1989008264A1 publication Critical patent/WO1989008264A1/fr

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/54Labware with identification means
    • B01L3/545Labware with identification means for laboratory containers
    • B01L3/5453Labware with identification means for laboratory containers for test tubes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/54Labware with identification means
    • B01L3/545Labware with identification means for laboratory containers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/4875Details of handling test elements, e.g. dispensing or storage, not specific to a particular test method
    • G01N33/48771Coding of information, e.g. calibration data, lot number
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/505Containers for the purpose of retaining a material to be analysed, e.g. test tubes flexible containers not provided for above

Definitions

  • the invention relates to a method for the automatic, fully selective analysis of blood or blood components without the use of a central EDP.
  • the request card is sent to the laboratory together with a blood sample located in a primary vascular system. There it is read into the EDP. The read-in data are processed by a control program which, depending on this, controls one or more automatic analyzers, to which the requirements for the respective sample are transmitted in this way.
  • a disadvantage of the known method is that the request card by hand must be completed and that * on the other hand - a central EDP for ' . the processing of the individual samples is required.
  • a further practiced method consists in assigning an in-laboratory bar code number to the sample to be processed, which is printed in the laboratory and attached to the primary vascular system containing the sample 5. This has the advantage that the bar code strips are always legible. The laboratory also keeps track of where a sample is located.
  • a disadvantage of this method is that coding laboratory errors may occur in the 0 transfer of data from the registration card to the.
  • Primary vascular system is understood to mean a main sample container which is filled with blood immediately when blood is drawn.
  • Secondary vascular system means sub-sample containers that are filled with sub-samples taken from the primary vascular system.
  • a method with the following steps is used to solve this task: filling blood into a vascular system; the vascular system is provided with an electronic code carrier before the filling of blood or immediately after the blood is drawn or later in the laboratory; Patient data and, if appropriate, further data are stored in the electronic code carrier, which either were entered before the blood was drawn or were entered immediately afterwards or at a later point in time and, if necessary, are completed in further steps; the vascular system provided with the code carrier is inserted with its complete data set into an analysis apparatus independently of a central EDP; the data electronically stored in the code carrier control the analysis apparatus and cause it to process the sample automatically, fully selectively; the analysis result can then be printed out in connection with all patient data directly on the analyzer.
  • the electronic code carrier has an electronic niche i memory in non-erasable version or in erasable version for read / write ; contains egg function.
  • a code carrier is, for example, from NEDAP-N. ' V. available in Groenlo, Holland. An embodiment of this .; Code carrier is described in DE-PS 27 48 584.
  • the known NEDAP code carrier is equipped with an IC specially developed for the application, so that it can be accommodated in a space-saving manner in a plastic tablet of, for example, 12 mm in diameter and 4 mm in height.
  • the encoding of the code carrier consists of polycarbonate. It is currently able to store, for example, 200 alphanumeric positions without a battery.
  • the data set of a primary vascular system can be electronically copied and transferred completely and without confusion to secondary vascular systems.
  • the secondary vascular systems can then be processed like primary vascular systems with a full data set.
  • Another advantage of the method according to the invention is that the battery-free electronic code carriers work practically without wear and can be reused indefinitely.
  • the analysis results can be entered directly into the memory of the electronic code carrier, so that all sample data are always available immediately and without the use of a central EDP. All you need to do is bring the electronic code carrier close to a reading head connected to a PC and controlled by it, then the sample data can be displayed on the PC screen immediately and, if necessary, also printed out.
  • Automatic sample distributor it is also possible to carry out other operations in addition to the analysis, for example the To further distribute vascular systems via an automatically working sample distribution station without a central EDP being necessary for this. In this way, the intrinsically prone to bidirectional data traffic with a central computer is avoided. In addition, simpler PCs can be used instead of an expensive, fast mainframe.
  • the battery-less electronic code carrier ' is the accommodated in a pocket of a bag-stored blood ö in a cap of a primary vascular system.
  • the blood bank can be read by a read / write head .
  • the electronic code carrier thus represents a discrete label for the blood bank bag.
  • the electronic code carrier is used in connection with a tubular vascular system, for example in connection with a primary vascular system or a secondary vascular system, it is expediently accommodated in a cap which is clipped onto the bottom of the primary vascular system.
  • the diameter of the separating tube does not increase, but only its length, so that the separating tube provided with the electronic code carrier can be easily inserted into the sample plate of a known analytical device.
  • the cap needs to seat 7 of the .Codelichs merely a recess for inserting the code carrier Tab ⁇ lettering have.
  • the separation tube a cannula cone
  • the cap has a needle plug
  • the code carrier tablet then lies on the other side of the cannula stopper and is held by plastic webs. In one embodiment of the invention, the webs are not connected to one another, so that the code carrier tablet comes out of the Cap can be broken out.
  • the battery-free electronic code carrier can also be inserted into an adapter tube if the primary or secondary vessel system used for the examination has a smaller diameter than conventional separation tubes and therefore has to be inserted into the sample plate of an analyzer anyway with the aid of an adapter tube.
  • a batteryless electronic code carrier can also be attached to other laboratory vessels, for example to microtiter plates and similar containers.
  • Figure 1 shows a first embodiment.
  • Figure 2 shows a second embodiment.
  • Figure 1 shows a separation tube 2 for blood collection with a symmetrical separation element 6 according to DE-PS 27 11 336.
  • the separating tube 2 is closed at its upper end by a stopper 1 and has a flat tube bottom 18 which is provided on the outside with a retaining ring 44.
  • the tube 2 consists of transparent plastic, which compresses during centrifugation and thereby widens somewhat in diameter, so that the separating element 6 can be moved to the tube bottom 18 under the influence of centrifugal force.
  • a plastic cap 30 is provided under the tube bottom 18, the outer diameter of which corresponds to the outer diameter of the separating tube 2, as is indicated by the dashed lines.
  • the bottom of the cap 30 is closed; its upper edge, however, is open, so that the cap 30 has the shape of a flat cup, in which a battery-free electronic code carrier 3 is inserted in the form of a tablet, for example 12 mm in diameter and 4 mm in height, with a cast-in electronic circuit.
  • FIG. 2 shows a second embodiment of the invention, in which only the lower part of a separation tube 2 1 is shown.
  • the separation tube 2 1 in this embodiment has a cannula cone 19 for attaching a cannula.
  • the cannula not shown, is used in a manner known per se for taking blood from a patient's vein. After the blood has been drawn, the separating tube 2 'must be closed in order to be able to be used directly as a primary vessel system in the sample plate of an analytical device, for example of the BM / Hitachi 717 type.
  • a cap 40 is clipped onto the tube bottom 18 of the separating tube 2 ′, which has an intermediate wall 22, onto which a cannula stopper 48 and a conical apron 46 concentrically surrounding the cannula stopper 48 are formed.
  • the cap 40 again has an upper edge which is provided with an annular bead 42 in order to snap behind the retaining ring 44 of the tube bottom 18.
  • the distance between the intermediate wall 22 and the annular bead 42 is selected such that the cannula stopper 48 is pressed into the cannula cone 19 in a sealed manner when the cap 40 is clipped onto the tube bottom 18, the conical apron 46 performing a centering and holding function.
  • the cannula stopper 48 is formed on the side of the intermediate wall 22 which faces the annular bead 42.
  • the cannula plug 48 has a slightly smaller diameter than the cannula bore at its tip for easier entry into the cannula bore, but increases in diameter in the direction of the intermediate wall 22, so that the cannula bore is reliably sealed.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

Selon un procédé d'analyse automatique entièrement sélective du sang ou de ses composants, on assujettit un support électronique de codage (3) dépourvu de batteries sur un conteneur primaire (2). Les données concernant le patient et l'échantillon sont enregistrées sans contact dans le support électronique de codage (3) de manière à pouvoir être lues à tout moment et partout où une tête de lecture électronique est disponible. Des échantillons de sang peuvent ainsi être analysés de manière automatique et entièrement sélective sans avoir recours à une installation centrale de traitement de données.
PCT/EP1989/000213 1988-03-04 1989-02-28 Procede d'analyse automatique entierement selective du sang ou des composants du sang WO1989008264A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3807079.0 1988-03-04
DE3807079 1988-03-04

Publications (1)

Publication Number Publication Date
WO1989008264A1 true WO1989008264A1 (fr) 1989-09-08

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1989/000213 WO1989008264A1 (fr) 1988-03-04 1989-02-28 Procede d'analyse automatique entierement selective du sang ou des composants du sang

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WO (1) WO1989008264A1 (fr)

Cited By (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0635305A1 (fr) * 1993-07-22 1995-01-25 Societe D'etudes, De Gestion, D'engineering Dispositif en forme de paillette pour la conservation d'un produit liquide ou pulvérulent
EP0637750A2 (fr) * 1993-08-05 1995-02-08 Roche Diagnostics GmbH Procédé d'analyse des échantillons liquides
EP0700719A1 (fr) * 1994-09-09 1996-03-13 Shin-Etsu Chemical Co., Ltd. Appareil automatique de mesure de proprietés physiques de solutions de derivés de cellulose
WO1996007479A1 (fr) * 1994-09-09 1996-03-14 Gay Freres Vente Et Exportation S.A. Dispositif d'enregistrement et de transfert d'informations pour analyses en eprouvette
EP0706825A1 (fr) * 1994-10-10 1996-04-17 Reinhard Grieb Porte-échantillons pour le sang, l'urine, ou pareil, avec porteur de données
WO1996014043A1 (fr) * 1994-11-02 1996-05-17 Zeneca Limited Reservoirs et dispositifs d'administration
WO1996036436A1 (fr) * 1995-04-25 1996-11-21 Irori Matrices programmables a distance et dotees de memoires, et leur utilisation
WO1997012680A3 (fr) * 1995-10-03 1997-08-21 Irori Matrices a memoires, capteurs a memoires et utilisations correspondantes
NL1003726C2 (nl) * 1996-08-01 1998-02-05 Micronic B V Reageerbuis met optisch leesbare codering.
WO1999003585A1 (fr) * 1997-07-16 1999-01-28 Clids Oy Eprouvette
WO1999010763A1 (fr) * 1997-08-21 1999-03-04 Carl Zeiss Jena Gmbh Support d'echantillons pouvant etre traite par informatique et procede d'analyse des echantillons
US5882338A (en) * 1993-05-04 1999-03-16 Zeneca Limited Syringes and syringe pumps
DE19740429A1 (de) * 1997-09-11 1999-03-25 Genom Analytik Gmbh Verfahren und Vorrichtung zur Entnahme von biologischen Proben
US5925562A (en) * 1995-04-25 1999-07-20 Irori Remotely programmable matrices with memories
US6019745A (en) * 1993-05-04 2000-02-01 Zeneca Limited Syringes and syringe pumps
DE19841554A1 (de) * 1998-09-11 2000-03-23 Biochip Technologies Gmbh Vorrichtung zur Aufnahme von festem oder flüssigem Probenmaterial
US6100026A (en) * 1995-04-25 2000-08-08 Irori Matrices with memories and uses thereof
US6284459B1 (en) 1995-04-25 2001-09-04 Discovery Partners International Solid support matrices with memories and combinatorial libraries therefrom
US6319668B1 (en) 1995-04-25 2001-11-20 Discovery Partners International Method for tagging and screening molecules
US6340588B1 (en) 1995-04-25 2002-01-22 Discovery Partners International, Inc. Matrices with memories
US6372293B1 (en) 1999-09-20 2002-04-16 Matrix Technologies Corporation Test tube with data matrix code markings
EP1210979A1 (fr) * 2000-11-29 2002-06-05 Advanced Biotechnologies Limited Eprouvettes avec chambre étanche aux fluides pour étiquettes
WO2002009020A3 (fr) * 2000-07-21 2002-09-19 Patram Patent And Trademark Ad Procede de manutention d'un objet
US6475443B1 (en) * 1997-04-28 2002-11-05 Sgt Exploitatie B.V. Device for storing and/or treating chemicals
GB2379739A (en) * 2001-09-14 2003-03-19 Thomas Fergus Hughes Labware with memory storage
DE19758633C2 (de) * 1997-09-11 2003-10-23 Biopsytec Gmbh Vorrichtung zur Entnahme von biologischen Proben
US6985870B2 (en) 2002-01-11 2006-01-10 Baxter International Inc. Medication delivery system
USRE39545E1 (en) 1995-02-02 2007-04-03 Nexus Biosystems, Inc. Methods and apparatus for synthesizing labeled combinatorial chemistry libraries
US7236936B2 (en) 1999-12-01 2007-06-26 B. Braun Medical, Inc. Security infusion pump with bar code reader

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3818188A (en) * 1971-10-26 1974-06-18 Philips Corp Device for positioning a data carrier in a reading apparatus
FR2393290A1 (fr) * 1977-05-31 1978-12-29 Siemens Ag Eprouvette pour echantillon pour des enceintes recevant des echantillons de liquides
US4196418A (en) * 1976-11-01 1980-04-01 N.V. Nederlandsche Apparatenfabriek Nedap Detection plate for an identification system
FR2555744A1 (fr) * 1983-11-30 1985-05-31 Philips Ind Commerciale Eprouvette avec moyens de memorisation des resultats d'analyse
GB2154982A (en) * 1984-02-29 1985-09-18 Constat Business Forms Limited Combined form and envelope

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3818188A (en) * 1971-10-26 1974-06-18 Philips Corp Device for positioning a data carrier in a reading apparatus
US4196418A (en) * 1976-11-01 1980-04-01 N.V. Nederlandsche Apparatenfabriek Nedap Detection plate for an identification system
FR2393290A1 (fr) * 1977-05-31 1978-12-29 Siemens Ag Eprouvette pour echantillon pour des enceintes recevant des echantillons de liquides
FR2555744A1 (fr) * 1983-11-30 1985-05-31 Philips Ind Commerciale Eprouvette avec moyens de memorisation des resultats d'analyse
GB2154982A (en) * 1984-02-29 1985-09-18 Constat Business Forms Limited Combined form and envelope

Cited By (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5882338A (en) * 1993-05-04 1999-03-16 Zeneca Limited Syringes and syringe pumps
US6019745A (en) * 1993-05-04 2000-02-01 Zeneca Limited Syringes and syringe pumps
EP0635305A1 (fr) * 1993-07-22 1995-01-25 Societe D'etudes, De Gestion, D'engineering Dispositif en forme de paillette pour la conservation d'un produit liquide ou pulvérulent
FR2707875A1 (fr) * 1993-07-22 1995-01-27 Gestion Engineering Et Dispositif en forme de paillette pour la conservation d'un produit liquide ou pulvérulent.
EP0637750A2 (fr) * 1993-08-05 1995-02-08 Roche Diagnostics GmbH Procédé d'analyse des échantillons liquides
EP0637750A3 (fr) * 1993-08-05 1997-02-19 Boehringer Mannheim Gmbh Procédé d'analyse des échantillons liquides.
EP0700719A1 (fr) * 1994-09-09 1996-03-13 Shin-Etsu Chemical Co., Ltd. Appareil automatique de mesure de proprietés physiques de solutions de derivés de cellulose
WO1996007479A1 (fr) * 1994-09-09 1996-03-14 Gay Freres Vente Et Exportation S.A. Dispositif d'enregistrement et de transfert d'informations pour analyses en eprouvette
US5777303A (en) * 1994-09-09 1998-07-07 Gay Freres, Vente Et Exportation S.A. Device for associating test tube samples with electronic labels for storage of identifying data
EP0706825A1 (fr) * 1994-10-10 1996-04-17 Reinhard Grieb Porte-échantillons pour le sang, l'urine, ou pareil, avec porteur de données
WO1996014043A1 (fr) * 1994-11-02 1996-05-17 Zeneca Limited Reservoirs et dispositifs d'administration
US5980501A (en) * 1994-11-02 1999-11-09 Zeneca Limited Reservoirs and delivery devices
USRE39545E1 (en) 1995-02-02 2007-04-03 Nexus Biosystems, Inc. Methods and apparatus for synthesizing labeled combinatorial chemistry libraries
USRE39571E1 (en) 1995-02-02 2007-04-17 Nexus Biosystems, Inc. Methods and apparatus for synthesizing labeled combinatorial chemistry libraries
USRE39606E1 (en) 1995-02-02 2007-05-01 Nexus Biosystems, Inc. Methods and apparatus for synthesizing labeled combinatorial chemistry libraries
US6284459B1 (en) 1995-04-25 2001-09-04 Discovery Partners International Solid support matrices with memories and combinatorial libraries therefrom
US6340588B1 (en) 1995-04-25 2002-01-22 Discovery Partners International, Inc. Matrices with memories
US5925562A (en) * 1995-04-25 1999-07-20 Irori Remotely programmable matrices with memories
US5961923A (en) * 1995-04-25 1999-10-05 Irori Matrices with memories and uses thereof
WO1996036436A1 (fr) * 1995-04-25 1996-11-21 Irori Matrices programmables a distance et dotees de memoires, et leur utilisation
US6100026A (en) * 1995-04-25 2000-08-08 Irori Matrices with memories and uses thereof
US6319668B1 (en) 1995-04-25 2001-11-20 Discovery Partners International Method for tagging and screening molecules
WO1997012680A3 (fr) * 1995-10-03 1997-08-21 Irori Matrices a memoires, capteurs a memoires et utilisations correspondantes
NL1003726C2 (nl) * 1996-08-01 1998-02-05 Micronic B V Reageerbuis met optisch leesbare codering.
US6270728B1 (en) 1996-08-01 2001-08-07 Micronic B.V. Test tube with optically readable coding
WO1998005427A1 (fr) * 1996-08-01 1998-02-12 Micronic B.V. Eprouvette pourvue d'un code a lecture optique
US6475443B1 (en) * 1997-04-28 2002-11-05 Sgt Exploitatie B.V. Device for storing and/or treating chemicals
US7097812B2 (en) 1997-04-28 2006-08-29 Sgt Exploitatie B.V. Device for storing and/or treating chemicals
US6733731B2 (en) 1997-04-28 2004-05-11 Sgt Exploitatie B.V. Device for storing and/or treating chemicals
US6652812B1 (en) 1997-07-16 2003-11-25 Clids Oy Specimen tube
WO1999003585A1 (fr) * 1997-07-16 1999-01-28 Clids Oy Eprouvette
WO1999010763A1 (fr) * 1997-08-21 1999-03-04 Carl Zeiss Jena Gmbh Support d'echantillons pouvant etre traite par informatique et procede d'analyse des echantillons
DE19740429A1 (de) * 1997-09-11 1999-03-25 Genom Analytik Gmbh Verfahren und Vorrichtung zur Entnahme von biologischen Proben
DE19758633C2 (de) * 1997-09-11 2003-10-23 Biopsytec Gmbh Vorrichtung zur Entnahme von biologischen Proben
DE19740429C2 (de) * 1997-09-11 2002-03-14 Biopsytec Gmbh Verfahren zur Entnahme von biologischen Proben
DE19758619C2 (de) * 1997-09-11 2003-12-18 Biopsytec Gmbh Vorrichtung zur Probenahme und Kennzeichnung eines Lebewesens
DE19841554A1 (de) * 1998-09-11 2000-03-23 Biochip Technologies Gmbh Vorrichtung zur Aufnahme von festem oder flüssigem Probenmaterial
US6372293B1 (en) 1999-09-20 2002-04-16 Matrix Technologies Corporation Test tube with data matrix code markings
US7236936B2 (en) 1999-12-01 2007-06-26 B. Braun Medical, Inc. Security infusion pump with bar code reader
WO2002009020A3 (fr) * 2000-07-21 2002-09-19 Patram Patent And Trademark Ad Procede de manutention d'un objet
US6884397B2 (en) 2000-11-29 2005-04-26 Advanced Biotechnologies Limited Sample tubes with fluid-tight labels
GB2370352A (en) * 2000-11-29 2002-06-26 Advanced Biotech Ltd Labelled sample tubes
EP1210979A1 (fr) * 2000-11-29 2002-06-05 Advanced Biotechnologies Limited Eprouvettes avec chambre étanche aux fluides pour étiquettes
JP2007147644A (ja) * 2000-11-29 2007-06-14 Advanced Biotechnologies Ltd 改良されたチューブ
GB2370352B (en) * 2000-11-29 2003-05-21 Advanced Biotech Ltd Sample tubes with labels
GB2379739B (en) * 2001-09-14 2005-06-08 Thomas Fergus Hughes Laboratory mounting, storage and prcessing members
GB2379739A (en) * 2001-09-14 2003-03-19 Thomas Fergus Hughes Labware with memory storage
US6985870B2 (en) 2002-01-11 2006-01-10 Baxter International Inc. Medication delivery system

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