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WO1988007010A1 - Valve pour aerosol - Google Patents

Valve pour aerosol Download PDF

Info

Publication number
WO1988007010A1
WO1988007010A1 PCT/GB1988/000197 GB8800197W WO8807010A1 WO 1988007010 A1 WO1988007010 A1 WO 1988007010A1 GB 8800197 W GB8800197 W GB 8800197W WO 8807010 A1 WO8807010 A1 WO 8807010A1
Authority
WO
WIPO (PCT)
Prior art keywords
valve
stem
metering chamber
seal
chamber
Prior art date
Application number
PCT/GB1988/000197
Other languages
English (en)
Inventor
Philip Bolton
Original Assignee
Riker Laboratories, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riker Laboratories, Inc. filed Critical Riker Laboratories, Inc.
Publication of WO1988007010A1 publication Critical patent/WO1988007010A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
    • B65D83/44—Valves specially adapted for the discharge of contents; Regulating devices
    • B65D83/52—Metering valves; Metering devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
    • B65D83/42—Filling or charging means
    • B65D83/425—Delivery valves permitting filling or charging

Definitions

  • This invention relates to a dispensing valve for use with an aerosol container and in particular to a dispensing valve capable of dispensing metered doses of the contents of an aerosol container.
  • a dispensing valve for use with an aerosol container and in particular to a dispensing valve capable of dispensing metered doses of the contents of an aerosol container.
  • aerosol devices to administer drug or other therapeutically active compounds by inhalation therapy is common, particularly for treatment of lung complaints such as asthma.
  • Aerosol dispensing containers are charged with a self-propelling liquid composition containing the medicament dispersed or dissolved therein and provided with a valve capable of discharging metered amounts of the composition.
  • Known aerosol dispensers having metering valves designed for inverted operation generally have a metering chamber and dipcup which retain a fresh charge immediately after a charge previously held in the metering chamber has been dispensed. This feature is incorporated in the valve to avoid the need to prime before use.
  • this type of arrangement particularly if the contents are held in the metering chamber for prolonged periods of time.
  • Prolonged intimate contact of many aerosol formulations intended for oral or nasal administration with the valve rubbers of metering chambers can result in leaching of components from the rubber mix, which may produce an unacceptable taste or in extreme cases cause the product within the metering chamber to become unstable.
  • British Patent Nos. 2004526B and 2086845B disclose metering dispensing valves for inverted operation which do not employ a dipcup arrangement and the metering chamber is drained when the aerosol container is positioned with the valve uppermost.
  • the metering chamber has an opening communicating with the interior of the aerosol container associated with a valve seal which is selectively blocked and exposed by a portion of the valve stem as it is moved from its operative to inoperative positions.
  • valve stem has a valve member of larger cross-section thereon, the valve member being arranged to enter the opening and make a sealing fit with the associated valve seal during movement of the stem from its inoperative to its operative position, to remain in a sealing fit when the stem reaches its operative position but to be completely disengaged from the opening when the stem is in the inoperative position and the said opening having an area such that when the valve stem is in the operative position and the valve member is disengaged from the opening material can freely enter or leave the metering chamber under the effect of gravity without the flow of material being significantly impeded and a return spring surrounding the valve member within the metering chamber and arranged to resist movement of the valve stem to its operative position.
  • the valve seal comprises an annulus positioned within the chamber engaging the periphery of the opening held in place by the return spring.
  • a swollen seal reduces the capacity of the metering chamber and also may reduce the aperture in the seal preventing free drainage of the contents within the metering chamber when the valve member is disengaged.
  • the action of the return spring on the seal may cause distortion of the seal causing it to tightly grip the valve member increasing friction the valve and impairing the easy operation of the valve.
  • the invention provides an improved metering dispensing valve in which these disadvantages are at least substantially overcome.
  • a valve for dispensing metered doses from an aerosol container when the container is held in an inverted position comprising a valve body with an internal metering chamber which is fixed with respect to the valve body; a valve stem having a valve member thereon, and outlet passage through which a charge can be dispensed from the metering chamber and a transfer port through which the charge can pass from the metering chamber to the outlet passage when the stem is disposed in an operative position; a first valve seal with which the valve stem is a sliding and sealing fit, the transfer port being so disposed that when the stem is in the inoperative position the charge to be dispensed cannot pass through it from the metering chamber; the metering chamber having an opening associated with a second valve seal through which material to be dispensed can pass when the stem is in the inoperative position, the valve member being constructed and arranged to enter the opening and make a sealing fit with the second valve seal during movement of the stem from its inoperative to its operative position,
  • the volume of the seal has no effect upon the capacity of the chamber and accordingly the dimensions of the seal may be selected from a wide range of sizes.
  • the seal may conveniently be held securely in place by a shroud fitted over the metering chamber thereby reducing to a minimum the area of the seal which is exposed to the contents of the aerosol and ensuring the seal will not become displaced during movement of the valve stem.
  • the shroud may also perform an additional function of retaining the seal of a pressure filling valve.
  • valve stem, metering chamber and shroud are constructed of metal or plastics material allowing the components to be made to close tolerances.
  • the valve of the invention does not allow either gas or liquid to be trapped in the metering chamber when the stem is in its inoperative position. Any gas that enters the valve is immediately released and replaced with liquid when the can is inverted.
  • the valve is therefore self-priming and will produce an improved shot weight consistency.
  • a free interchange of liquid will occur between the metering chamber and the can contents.
  • the need to fit a dipcup to ensure efficient removal of the maximum amount of product from the can is obviated thereby, reducing the overall height of the valve.
  • the result is a very short squat valve which fills the nose of the ferrule and leaves a negligible amount of product in the can at the end of its life.
  • valve member is completely disengaged from the second valve seal when the valve stem is in its inoperative position.
  • valve member extends through the second valve seal both in the operative and inoperative positions of the valve stem, the end of the valve member extending through the second valve seal having a passage extending from the end and communicating with one or more ports which communicate with the metering chamber only when the valve stem is in its inoperative position thereby allowing material to freely enter or leave the metering chamber.
  • Figure 1 represents a vertical cross-section through a valve in accordance with the invention
  • Figure 2 represents a vertical cross-section through a different valve in accordance with the invention.
  • the valve comprises a ferrule or cap 2 intended to be crimped to the neck of an aerosol container.
  • the metering chamber 4 is of constant volume and is fixed with respect to the cap 2.
  • a valve stem 6 extends into the chamber 4 through a first valve seal 8 in sliding sealing engagement with said valve seal.
  • the valve stem 6 has a valve member 10 having a shoulder 12 which makes sealing contact with the valve seal 8 when the valve stem 6 is in its inoperative position.
  • the base of the chamber 4 is provided with an opening 14 communicating with the aerosol container (not shown) .
  • a second annular valve seal 16 is provided outside the chamber engaging the periphery of the opening 14.
  • the seal 16 is held in place by a shroud 18 fitted over the chamber 4 and provided with an opening 20 aligned with the openings of the seal 16 and chamber.
  • valve stem 5 When the valve stem 5 is moved downwards towards its operative position the valve member 10 engages the second valve seal 16 sealing the opening 14 of the chamber. Further movement of the valve stem maintains the seal and the valve stem will reach its operative position in which the port will communicate with the chamber 4 allowing discharge of the contents therein via passage 24 thereby emptying the chamber of the predetermined volume of contents.
  • the valve stem 5 is biased towards its inoperative position by return spring 26 positioned within the chamber 4 and acting between the shoulder 12 of the valve stem 6 and the base of the chamber.
  • the valve of the invention may conveniently incorporate a pressure filling valve.
  • the pressure filling valve comprises a port 28 positioned in the side of the chamber 4 towards the top of the chamber and a cylindrical valve seal 30 extending around the outside of the chamber and covering the port 28.
  • the shroud 18 is provided with a circumferential flange 32 which prevents displacement of the seal 30.
  • the seal 30 is firmly retained between the flange 32 and circumferential flange 34 of the chamber 4.
  • pressure filing valve which may be employed in the valves of the invention is the construction disclosed in British Patent No. 1,287,126 which is incorporated herein by reference.
  • a pressure filling valve comprises one or more apertures (not shown) in the flange 34, preferably a plurality of radial slots. The apertures or slots are normally sealed by the seal 8.
  • FIG. 2 represents a further valve in accordance with the invention in which identical parts to those in Figure 1 have the same reference numerals.
  • the valve differs from that in Figure 1 in that the valve member 10 extends through the lower seal 16 in both the inoperative and operative positions of the. valve stem 6 thereby ensuring correct alignment of the valve stem.
  • the valve member 10 has a passage 40 and one or more apertures 42 which facilitates free flow of material between the metering chamber and container when the valve stem is in its inoperative position. As the valve stem is depressed the aperture 42 is closed by the seal 16 thereby sealing the metering chamber.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Nozzles (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

Une valve de dosage à remplissage et écoulement rapide destinée à être utilisée avec un récipient aérosol, dans laquelle le joint d'étanchéité inférieur de la valve (16) de la chambre de dosage (4) est positionné à l'extérieur de la chambre de dosage pour assurer un fonctionnement fiable et un volume constant du dosage à l'intérieur de la chambre de dosage.
PCT/GB1988/000197 1987-03-13 1988-03-11 Valve pour aerosol WO1988007010A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8705965 1987-03-13
GB878705965A GB8705965D0 (en) 1987-03-13 1987-03-13 Aerosol valve

Publications (1)

Publication Number Publication Date
WO1988007010A1 true WO1988007010A1 (fr) 1988-09-22

Family

ID=10613885

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1988/000197 WO1988007010A1 (fr) 1987-03-13 1988-03-11 Valve pour aerosol

Country Status (5)

Country Link
EP (1) EP0305441A1 (fr)
JP (1) JPH01503045A (fr)
AU (1) AU1425988A (fr)
GB (1) GB8705965D0 (fr)
WO (1) WO1988007010A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5421492A (en) * 1993-11-02 1995-06-06 Glaxo Inc. Metered aerosol dispensing apparatus and method of use thereof
US5921447A (en) * 1997-02-13 1999-07-13 Glaxo Wellcome Inc. Flow-through metered aerosol dispensing apparatus and method of use thereof
US6089256A (en) * 1997-09-03 2000-07-18 Bespak Plc. Metering valves for pressurized dispensing containers
GB2361229A (en) * 2000-04-14 2001-10-17 Presspart Mfg Ltd Metering valve

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2968427A (en) * 1955-06-28 1961-01-17 Meshberg Philip Valve for aerosol container
US3727806A (en) * 1971-05-19 1973-04-17 Neotechnic Eng Ltd Valve assemblies for aerosol containers
GB2086845A (en) * 1977-09-22 1982-05-19 Glaxo Group Ltd Aerosol Valve
EP0191614A2 (fr) * 1985-02-12 1986-08-20 Bespak plc Valves pour récipients de distribution pressurisés

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2968427A (en) * 1955-06-28 1961-01-17 Meshberg Philip Valve for aerosol container
US3727806A (en) * 1971-05-19 1973-04-17 Neotechnic Eng Ltd Valve assemblies for aerosol containers
GB2086845A (en) * 1977-09-22 1982-05-19 Glaxo Group Ltd Aerosol Valve
EP0191614A2 (fr) * 1985-02-12 1986-08-20 Bespak plc Valves pour récipients de distribution pressurisés

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5421492A (en) * 1993-11-02 1995-06-06 Glaxo Inc. Metered aerosol dispensing apparatus and method of use thereof
US5921447A (en) * 1997-02-13 1999-07-13 Glaxo Wellcome Inc. Flow-through metered aerosol dispensing apparatus and method of use thereof
US6089256A (en) * 1997-09-03 2000-07-18 Bespak Plc. Metering valves for pressurized dispensing containers
US6095182A (en) * 1997-09-03 2000-08-01 Bespak Plc Metering valves for pressurised dispensing containers
GB2361229A (en) * 2000-04-14 2001-10-17 Presspart Mfg Ltd Metering valve
WO2001079079A1 (fr) * 2000-04-14 2001-10-25 Presspart Manufacturing Ltd. Assemblage de soupape pour des distributeurs de doses

Also Published As

Publication number Publication date
JPH01503045A (ja) 1989-10-19
GB8705965D0 (en) 1987-04-15
AU1425988A (en) 1988-10-10
EP0305441A1 (fr) 1989-03-08

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