WO1987005536A1 - Procede et appareil pour recueillir et disperser des particules ferromagnetiques dans un milieu fluide - Google Patents
Procede et appareil pour recueillir et disperser des particules ferromagnetiques dans un milieu fluide Download PDFInfo
- Publication number
- WO1987005536A1 WO1987005536A1 PCT/SE1987/000120 SE8700120W WO8705536A1 WO 1987005536 A1 WO1987005536 A1 WO 1987005536A1 SE 8700120 W SE8700120 W SE 8700120W WO 8705536 A1 WO8705536 A1 WO 8705536A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sleeve
- nose
- passageway
- magnet
- permanent magnet
- Prior art date
Links
- 239000002245 particle Substances 0.000 title claims abstract description 29
- 230000005294 ferromagnetic effect Effects 0.000 title claims abstract description 17
- 238000000034 method Methods 0.000 title claims abstract description 13
- 239000012530 fluid Substances 0.000 title description 3
- 239000007788 liquid Substances 0.000 claims abstract description 18
- 239000004033 plastic Substances 0.000 claims abstract description 7
- 230000005291 magnetic effect Effects 0.000 claims abstract description 5
- 239000000463 material Substances 0.000 claims abstract description 5
- 230000000694 effects Effects 0.000 claims description 5
- 239000007795 chemical reaction product Substances 0.000 claims description 4
- 239000000376 reactant Substances 0.000 claims description 4
- 239000007767 bonding agent Substances 0.000 claims 1
- 230000005389 magnetism Effects 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000003463 adsorbent Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000006249 magnetic particle Substances 0.000 description 1
- 239000002991 molded plastic Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000004804 winding Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/284—Magnetic plugs and dipsticks with associated cleaning means, e.g. retractable non-magnetic sleeve
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00457—Dispensing or evacuation of the solid phase support
- B01J2219/00459—Beads
- B01J2219/00468—Beads by manipulation of individual beads
Definitions
- the present invention relates to a method and an apparatus for collecting and dispersing ferromag ⁇ netic particles in a fluid medium.
- US-3,985,649 discloses a process for separating a substance from a liquid in a container utilising magnetic forces.
- the substance is formed of ferromag ⁇ netic particles which are actuated, for the said sepa ⁇ ration, by means of an electromagnet immersed in the liquid.
- the ferromagnetic particles may have been formed of a ferromagnetic core and a reaction product bonded thereto, optionally via a coating, and formed of a first reactant bonded to the core or the coating prior to the introduction of the cores into the liquid, and a second reactant within the liquid.
- the electro ⁇ magnet is energised and then attracts the particles and can be removed from the liquid and the container together with the particles.
- the ferromagnetic particles thus removed from the liquid and the reaction product which may be bonded thereto, can be subjected to further processing steps in other liquids, in which case the electromagnet may be deenergised.
- the electrical lead-ins of the elec- tromagnet constitute an obstacle to easy and convenient handling of the magnet.
- the thin-walled, nose-shaped end of the plastic sleeve which is permeable in respect of magnetism but free of remanence, causes the ferromagnetic par- tides to collect around this end when the permanent magnet is inserted therein, the shoulder interconnect ⁇ ing the nose and the relatively thick jacket wall preventing said particles from following, on the outer side of said jacket wall, the movement of the magnet when displaced from the nose in order to disperse the particles.
- the sleeve preferably is an inexpensive mass- produced single-service plastic product for collect ⁇ ing and dispersing the ferromagnetic particles.
- the invention will now be described in more detail, reference being had to the accompanying drawing illu ⁇ strating an uncomplicated basic embodiment of an appa ⁇ ratus for carrying the method according to the inven ⁇ tion into effect.
- a test tube 1 contains a liquid 2 with ferromagnetic particles 3.
- An apparatus accord ⁇ ing to the invention, or a probe, for collecting and dispersing these particles is designated 4. It com ⁇ prises a cylindrical, for example injection-moulded plastic sleeve 5 having a closed nose-shaped end 6.
- the sleeve 5 has a passageway 7 which is of uniform width and extends from the open end 8 of the sleeve into the nose 6.
- the nose 6 thus has a thinner jacket wall than the body 9 of the sleeve, and also a thin end wall.
- the passageway 7 accommodates a permanent magnet 10 for reciprocal movement within the passage ⁇ way 7 in the longitudinal direction thereof by means of a shank 11 attached to said magnet in some suitable manner and extending through the open end 8.
- a coiled spring 12 may be positioned between a flange 13 on the shank and a flange 14 on the sleeve.
- the plastic material for the sleeve is so select ⁇ ed that it is permeable to the magnetic field of the magnet 10 at the thin nose wall, but less permeable to this field via the thicker body wall 9.
- the plastic material has minimum residual magnetism (remanence), if any at all.
- the magnet 10 When the probe 4 is inserted in the tube 1 and the magnet 10 is moved into the nose 6, the spring 12 being compressed between the flanges 13 and 14 which are held between the fingers of one hand, the ferromagnetic particles 3 will collect on and adhere to the nose.
- the magnet When the magnet is moved in the opposite direction, which may be achieved by easing the finger pressure on the flange 13, the particles 3 are released from the sleeve 5. They cannot accompany the magnet 10 in its upward movement because of the shoulder between the nose 6 and the jacket wall 9 of the body.
- magnetic particles 3 to which adheres a reactant/reaction product/absorbent/adsorbent or the like originating in the liquid 2 are transferred to another test tube containing another liquid for reaction or further treatment therein, after dispersion in said other liquid.
- the construction described above is a basic one. It may be made more sophisticated in a manner obvious to those skilled in the art by providing, for example, means for locking the magnet 10 in the collecting position and the releasing/dispersing position, for example by means of a mechanism resembling the mechanism of a ballpoint pen for locking the retracted and ex ⁇ tended positions of a spring-loaded ink cartridge.
- a person skilled in the art will have no difficulty in devising a mechanism to provide for rotatability of the sleeve 5 about the shank 11 and the magnet 10 by the same hand which effects longitudinal movement of the magnet 10. Such rotation may be accomplished by means of a rack and gear mechanism, a clock-winding spring, etc.
- the advantage of having a rotatable sleeve 5, especially if the sleeve is provided with wings, is that the liquid and the ferromagnetic particles there ⁇ in can be agitated, possibly after they have been released by the sleeve 5.
Landscapes
- Soft Magnetic Materials (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
Un procédé et un appareil, servant à recueillir et à disperser des particules ferromagnétiques dans un milieu gazeux ou liquide, utilise un aimant qui est introduit dans ledit milieu. Un manchon (5), constitué en un matériau plastique perméable au champ magnétique mais sans rémanence et ayant une extrémité de bec (6) à paroi mince et une enveloppe à paroi mince, est également utilisé. Un corps d'aimant permanent (10) qui, une fois fixé à des moyens d'actionnement (11, 13), peut être déplacé à l'intérieur dudit passage dans sa direction longitudinale à l'aide desdits moyens d'actionnement à partir de l'extrémité de manchon ouverte, est monté dans le passage (7) du manchon. Lorsqu'il s'agit de recueillir les particules ferromagnétiques (3), ledit aimant permanent est déplacé à l'aide desdits moyens d'actionnement dans l'extrémité de bec fermé et, lorsqu'il s'agit de disperser lesdites particules, ledit aimant permanent est déplacé dans une position espacée du bec.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8601143-3 | 1986-03-12 | ||
SE8601143A SE8601143L (sv) | 1986-03-12 | 1986-03-12 | Sett och anordning for samling och spridning av ferromagnetiska partiklar i ett fluidformigt medium |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1987005536A1 true WO1987005536A1 (fr) | 1987-09-24 |
Family
ID=20363796
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/SE1987/000120 WO1987005536A1 (fr) | 1986-03-12 | 1987-03-11 | Procede et appareil pour recueillir et disperser des particules ferromagnetiques dans un milieu fluide |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU7127787A (fr) |
SE (1) | SE8601143L (fr) |
WO (1) | WO1987005536A1 (fr) |
Cited By (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2679660A1 (fr) * | 1991-07-22 | 1993-01-29 | Pasteur Diagnostics | Procede et dispositif magnetique d'analyse immunologique sur phase solide. |
WO1994018565A1 (fr) * | 1993-02-01 | 1994-08-18 | Labsystems Oy | Procede et dispositif de dosage par liaison specifique a des particules magnetiques |
WO1995000247A1 (fr) * | 1993-06-21 | 1995-01-05 | Labsystems Oy | Procede de separation |
FR2710632A1 (fr) * | 1993-09-28 | 1995-04-07 | Mercier Dominique | Dispositif de captation magnétique à nettoyage mécanique et son utilisation au débouage des circuits de chauffage. |
EP0687505A1 (fr) * | 1994-06-16 | 1995-12-20 | Roche Diagnostics GmbH | Méthode de séparation magnétique pour des composants d'un liquide |
WO1996012960A1 (fr) * | 1994-10-20 | 1996-05-02 | Labsystems Oy | Separation de particules comportant une etape de pre-concentration |
WO1996012961A1 (fr) * | 1994-10-20 | 1996-05-02 | Labsystems Oy | Procede de separation a deux phases |
WO1996012958A1 (fr) * | 1994-10-20 | 1996-05-02 | Labsystems Oy | Dispositif de separation pour microparticules, comportant une tige magnetique |
WO1996012959A1 (fr) * | 1994-10-20 | 1996-05-02 | Labsystems Oy | Dispositif de transfert de particules magnetiques |
NL1001427C2 (nl) * | 1995-10-16 | 1997-04-17 | Paulus Wolfs | Inrichting voor het verwijderen van magnetiseerbare delen. |
US5837144A (en) * | 1994-06-16 | 1998-11-17 | Boehringer Mannheim Gmbh | Method of magnetically separating liquid components |
WO1999004239A2 (fr) * | 1997-07-16 | 1999-01-28 | Heermann Klaus Hinrich | Crayon magnetique pour la concentration et la separation de particules |
WO1999040444A1 (fr) * | 1998-02-06 | 1999-08-12 | Bio-Magnetics Ltd. | Dispositif et systeme de transfert de materiau |
WO1999042832A1 (fr) * | 1998-02-23 | 1999-08-26 | Bio-Nobile Oy | Dispositif et procede de transfert de particules magnetiques |
US6197597B1 (en) | 1993-02-01 | 2001-03-06 | Labsystems Oy | Solid phase immunoassay with carriers matching the shape of sample wells |
WO2001068263A1 (fr) * | 2000-03-14 | 2001-09-20 | Thermo Labsystems Oy | Recipient et barre |
WO2004035217A1 (fr) * | 2002-10-18 | 2004-04-29 | Bio-Nobile Oy | Procede de transfert magnetique, dispositif permettant de transferer des microparticules et unite de reacteur |
JP2004229657A (ja) * | 2003-01-29 | 2004-08-19 | Bionex Inc | 核酸又は様々な生物学的物質を分離及び精製するためのキットと、このキットを用いて生物学的物質の分離又は精製操作を自動化するためのシステム |
WO2005037440A1 (fr) * | 2003-10-20 | 2005-04-28 | Bio-Nobile Oy | Procede d'enrichissement magnetique, ensemble reacteur pour microparticules et ensemble aimant |
US6908759B2 (en) | 2001-10-31 | 2005-06-21 | Bionex, Inc. | Method of manufacturing kit for isolation nucleic acids or biological materials |
US7534081B2 (en) | 2005-05-24 | 2009-05-19 | Festo Corporation | Apparatus and method for transferring samples from a source to a target |
US7597520B2 (en) | 2005-05-24 | 2009-10-06 | Festo Corporation | Apparatus and method for transferring samples from a source to a target |
JP2010506172A (ja) * | 2006-10-06 | 2010-02-25 | プロメガ・コーポレーション | 磁性粒子を溶液から分離する装置および方法 |
US7799281B2 (en) | 2007-01-16 | 2010-09-21 | Festo Corporation | Flux concentrator for biomagnetic particle transfer device |
DE102009021201A1 (de) | 2009-05-13 | 2010-11-25 | Stratec Biomedical Systems Ag | Stabanordnung und Verfahren zur Extraktion magnetisierbarer Partikel aus Lösungen |
WO2011051192A1 (fr) * | 2009-10-30 | 2011-05-05 | Snecma | Dispositif et procede de recuperation de particules magnetiques piegees sur un bouchon magnetique |
FR2957823A1 (fr) * | 2010-03-29 | 2011-09-30 | Snecma | Dispositif et procede de recuperation de particules magnetiques piegees sur un bouchon magnetique |
DE202011104192U1 (de) | 2010-08-17 | 2011-11-25 | Netzsch-Feinmahltechnik Gmbh | Vorrichtung zum Entfernen von magnetisierbaren Verunreinigungen aus Fettmassen |
US8071395B2 (en) | 2007-12-12 | 2011-12-06 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and apparatus for magnetic separation of cells |
RU2444721C1 (ru) * | 2010-11-03 | 2012-03-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Юго-Западный государственный университет" (ЮЗ ГУ) | Способ определения количества ферромагнитных частиц в потоке жидкости или газа и устройство его осуществления |
WO2012122627A1 (fr) * | 2011-03-11 | 2012-09-20 | Guisheng Yang | Dispositif et procédé de piégeage de particules magnétiques |
WO2014007074A1 (fr) * | 2012-07-06 | 2014-01-09 | 株式会社 日立ハイテクノロジーズ | Kit d'extraction d'acides nucléiques, et extracteur d'acides nucléiques |
US8900449B2 (en) | 2012-03-13 | 2014-12-02 | Cpc Corporation, Taiwan | Magnetic filter for refining and chemical industries |
US9012201B2 (en) | 2005-12-02 | 2015-04-21 | Biocontrol Systems, Inc. | Enrichment unit for biological components and an enrichment method |
US9329194B2 (en) | 2007-11-05 | 2016-05-03 | Abbott Laboratories | Automated analyzer for clinical laboratory |
DE102015218008A1 (de) * | 2015-09-18 | 2017-03-23 | Hamilton Bonaduz Ag | Magnetische Trennvorrichtung mit mechanischer Aktivierung und Deaktivierung |
EP2727651A3 (fr) * | 2012-11-05 | 2017-04-26 | Hamilton Sundstrand Corporation | Système et procédé pour enlever des copeaux d'un collecteur de copeaux magnétiques |
US10458998B2 (en) * | 2006-07-28 | 2019-10-29 | Qiagen Gmbh | Device for processing samples |
EP3405288A4 (fr) * | 2016-01-19 | 2020-01-01 | Shanxi Zdgsy Bio-Scientific Co., Ltd. | Dispositif de séparation de substances biologiques multifonction |
US20230149949A1 (en) * | 2015-04-29 | 2023-05-18 | Fleenor Manufacturing, Inc. | Filter Element With Magnetic Array |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2970002A (en) * | 1959-01-20 | 1961-01-31 | Laviano Samuel | Magnetic pickup |
EP0140787A2 (fr) * | 1983-10-27 | 1985-05-08 | INSTITUT PASTEUR Fondation reconnue d'utilité publique | Perfectionnements apportés aux moyens magnétiques destinés à retirer des billes de gel magnétique d'un fluide de dosage |
WO1986006493A1 (fr) * | 1985-04-29 | 1986-11-06 | Labsystems Oy | Procede et dispositif d'execution d'essais immunologiques |
-
1986
- 1986-03-12 SE SE8601143A patent/SE8601143L/ not_active Application Discontinuation
-
1987
- 1987-03-11 AU AU71277/87A patent/AU7127787A/en not_active Abandoned
- 1987-03-11 WO PCT/SE1987/000120 patent/WO1987005536A1/fr unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2970002A (en) * | 1959-01-20 | 1961-01-31 | Laviano Samuel | Magnetic pickup |
EP0140787A2 (fr) * | 1983-10-27 | 1985-05-08 | INSTITUT PASTEUR Fondation reconnue d'utilité publique | Perfectionnements apportés aux moyens magnétiques destinés à retirer des billes de gel magnétique d'un fluide de dosage |
WO1986006493A1 (fr) * | 1985-04-29 | 1986-11-06 | Labsystems Oy | Procede et dispositif d'execution d'essais immunologiques |
Cited By (86)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5558839A (en) * | 1991-07-22 | 1996-09-24 | Pasteur Sanofi Diagnostic | Magnetic device for immunological analysis of a solid phase |
EP0528708A1 (fr) * | 1991-07-22 | 1993-02-24 | Pasteur Sanofi Diagnostics | Procédé et dispositif magnétique d'analyse immunologique sur phase solide |
US5318914A (en) * | 1991-07-22 | 1994-06-07 | Pasteur Sanofi Diagnostics | Process and magnetic device for immunological analysis of a solid phase |
FR2679660A1 (fr) * | 1991-07-22 | 1993-01-29 | Pasteur Diagnostics | Procede et dispositif magnetique d'analyse immunologique sur phase solide. |
EP1130397A2 (fr) * | 1993-02-01 | 2001-09-05 | Thermo Labsystems Oy | Equipment pour la détermination d'un analyte dans un échantillon |
US6040192A (en) * | 1993-02-01 | 2000-03-21 | Labsystems Oy | Method and means for magnetic particle specific binding assay |
US6197597B1 (en) | 1993-02-01 | 2001-03-06 | Labsystems Oy | Solid phase immunoassay with carriers matching the shape of sample wells |
US6447729B1 (en) * | 1993-02-01 | 2002-09-10 | Labsystems Oy | Method and means for magnetic particle specific binding assay |
WO1994018565A1 (fr) * | 1993-02-01 | 1994-08-18 | Labsystems Oy | Procede et dispositif de dosage par liaison specifique a des particules magnetiques |
EP1130397A3 (fr) * | 1993-02-01 | 2004-01-14 | Thermo Electron Oy | Equipment pour la détermination d'un analyte dans un échantillon |
WO1995000247A1 (fr) * | 1993-06-21 | 1995-01-05 | Labsystems Oy | Procede de separation |
US5647994A (en) * | 1993-06-21 | 1997-07-15 | Labsystems Oy | Method and apparatus for separating magnetic particles from a solution |
FR2710632A1 (fr) * | 1993-09-28 | 1995-04-07 | Mercier Dominique | Dispositif de captation magnétique à nettoyage mécanique et son utilisation au débouage des circuits de chauffage. |
US5837144A (en) * | 1994-06-16 | 1998-11-17 | Boehringer Mannheim Gmbh | Method of magnetically separating liquid components |
EP0687505A1 (fr) * | 1994-06-16 | 1995-12-20 | Roche Diagnostics GmbH | Méthode de séparation magnétique pour des composants d'un liquide |
WO1996012958A1 (fr) * | 1994-10-20 | 1996-05-02 | Labsystems Oy | Dispositif de separation pour microparticules, comportant une tige magnetique |
WO1996012959A1 (fr) * | 1994-10-20 | 1996-05-02 | Labsystems Oy | Dispositif de transfert de particules magnetiques |
US6448092B1 (en) | 1994-10-20 | 2002-09-10 | Thermo Labsystems Oy | Separation device for microparticles involving a magnetic rod |
WO1996012961A1 (fr) * | 1994-10-20 | 1996-05-02 | Labsystems Oy | Procede de separation a deux phases |
US5942124A (en) * | 1994-10-20 | 1999-08-24 | Labsystems, Oy | Magnetic particle transfer device |
US6207463B1 (en) | 1994-10-20 | 2001-03-27 | Labsystems Oy | Separation device for microparticles involving a magnetic rod |
US6020211A (en) * | 1994-10-20 | 2000-02-01 | Labsystems Oy | Separation of magnetic microparticles involving a preconcentration step |
WO1996012960A1 (fr) * | 1994-10-20 | 1996-05-02 | Labsystems Oy | Separation de particules comportant une etape de pre-concentration |
US6065605A (en) * | 1994-10-20 | 2000-05-23 | Labsystems Oy | Two-stage separation method |
NL1001427C2 (nl) * | 1995-10-16 | 1997-04-17 | Paulus Wolfs | Inrichting voor het verwijderen van magnetiseerbare delen. |
WO1997014502A1 (fr) * | 1995-10-16 | 1997-04-24 | Paulus Wolfs | Dispositif d'extraction de parties magnetisables |
US6077333A (en) * | 1995-10-16 | 2000-06-20 | Wolfs; Paulus | Device for removing magnetizable parts |
US6403038B1 (en) | 1997-07-16 | 2002-06-11 | Klaus-Hinrich Heermann | Magnetic pin for concentrating and separating particles |
WO1999004239A3 (fr) * | 1997-07-16 | 1999-04-08 | Heermann Klaus Hinrich | Crayon magnetique pour la concentration et la separation de particules |
WO1999004239A2 (fr) * | 1997-07-16 | 1999-01-28 | Heermann Klaus Hinrich | Crayon magnetique pour la concentration et la separation de particules |
WO1999040444A1 (fr) * | 1998-02-06 | 1999-08-12 | Bio-Magnetics Ltd. | Dispositif et systeme de transfert de materiau |
US6409925B1 (en) * | 1998-02-06 | 2002-06-25 | Bio-Magnetics Ltd. | Device and system for transfer of material |
WO1999042832A1 (fr) * | 1998-02-23 | 1999-08-26 | Bio-Nobile Oy | Dispositif et procede de transfert de particules magnetiques |
US6468810B1 (en) | 1998-02-23 | 2002-10-22 | Bio-Nobile Oy | Magnetic particle transfer device and method |
WO2001068263A1 (fr) * | 2000-03-14 | 2001-09-20 | Thermo Labsystems Oy | Recipient et barre |
US6596162B2 (en) | 2000-03-14 | 2003-07-22 | Thermo Labsystems Oy | Vessel and rod |
EP1266694A1 (fr) * | 2000-03-14 | 2002-12-18 | Thermo Labsystems Oy | Cuve et barre magnétique |
US6908759B2 (en) | 2001-10-31 | 2005-06-21 | Bionex, Inc. | Method of manufacturing kit for isolation nucleic acids or biological materials |
WO2004035217A1 (fr) * | 2002-10-18 | 2004-04-29 | Bio-Nobile Oy | Procede de transfert magnetique, dispositif permettant de transferer des microparticules et unite de reacteur |
US7622046B2 (en) * | 2002-10-18 | 2009-11-24 | Biocontrol Systems, Inc. | Magnetic transfer method, a device for transferring microparticles and a reactor unit |
JP2004229657A (ja) * | 2003-01-29 | 2004-08-19 | Bionex Inc | 核酸又は様々な生物学的物質を分離及び精製するためのキットと、このキットを用いて生物学的物質の分離又は精製操作を自動化するためのシステム |
WO2005037440A1 (fr) * | 2003-10-20 | 2005-04-28 | Bio-Nobile Oy | Procede d'enrichissement magnetique, ensemble reacteur pour microparticules et ensemble aimant |
US8084271B2 (en) | 2003-10-20 | 2011-12-27 | Biocontrol Systems, Inc. | Method and a device for treating microparticles |
EP1680231B1 (fr) * | 2003-10-20 | 2018-03-21 | BioControl Systems, Inc. | Procédé et dispositif pour traiter des microparticules |
US9274032B2 (en) | 2003-10-20 | 2016-03-01 | Biocontrol Systems, Inc. | Method and a device for treating microparticles |
EP2465612A3 (fr) * | 2003-10-20 | 2014-04-02 | BioControl Systems, Inc. | Procédé d'enrichissement magnétique, unité de réacteur pour microparticules et unité d'aimant |
US8430247B2 (en) | 2003-10-20 | 2013-04-30 | Biocontrol Systems, Inc. | Method and a device for treating microparticles |
US8247204B2 (en) | 2003-10-20 | 2012-08-21 | Biocontrol Systems, Inc. | Magnetic enrichment method, a reactor unit for micro particles and a magnet unit |
EP2465612A2 (fr) | 2003-10-20 | 2012-06-20 | BioControl Systems, Inc. | Procédé d'enrichissement magnétique, unité de réacteur pour microparticules et unité d'aimant |
US7534081B2 (en) | 2005-05-24 | 2009-05-19 | Festo Corporation | Apparatus and method for transferring samples from a source to a target |
US7597520B2 (en) | 2005-05-24 | 2009-10-06 | Festo Corporation | Apparatus and method for transferring samples from a source to a target |
US7841824B2 (en) | 2005-05-24 | 2010-11-30 | Festo Corporation | Method for transferring magnetic samples from a source to a target |
US9012201B2 (en) | 2005-12-02 | 2015-04-21 | Biocontrol Systems, Inc. | Enrichment unit for biological components and an enrichment method |
US10458998B2 (en) * | 2006-07-28 | 2019-10-29 | Qiagen Gmbh | Device for processing samples |
JP2010506172A (ja) * | 2006-10-06 | 2010-02-25 | プロメガ・コーポレーション | 磁性粒子を溶液から分離する装置および方法 |
US7799281B2 (en) | 2007-01-16 | 2010-09-21 | Festo Corporation | Flux concentrator for biomagnetic particle transfer device |
US9329194B2 (en) | 2007-11-05 | 2016-05-03 | Abbott Laboratories | Automated analyzer for clinical laboratory |
US8071395B2 (en) | 2007-12-12 | 2011-12-06 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and apparatus for magnetic separation of cells |
US9267943B2 (en) | 2007-12-12 | 2016-02-23 | The Board Of Trustees Of The Leland Stanford Junior University | Apparatus for magnetic separation of cells |
US8454825B2 (en) | 2009-05-13 | 2013-06-04 | Stratec Biomedical Ag | Rod assembly and a method for the extraction of magnetizable particles from solutions |
DE102009021201A1 (de) | 2009-05-13 | 2010-11-25 | Stratec Biomedical Systems Ag | Stabanordnung und Verfahren zur Extraktion magnetisierbarer Partikel aus Lösungen |
FR2951961A1 (fr) * | 2009-10-30 | 2011-05-06 | Snecma | Dispositif et procede de recuperation de particules magnetiques piegees sur un bouchon magnetique |
US9248454B2 (en) | 2009-10-30 | 2016-02-02 | Snecma | Device and method for recovering magnetic particles trapped on a magnetic plug |
CN102596416A (zh) * | 2009-10-30 | 2012-07-18 | 斯奈克玛 | 回收磁性塞上被捕集的磁微粒的装置和方法 |
WO2011051192A1 (fr) * | 2009-10-30 | 2011-05-05 | Snecma | Dispositif et procede de recuperation de particules magnetiques piegees sur un bouchon magnetique |
RU2541685C2 (ru) * | 2009-10-30 | 2015-02-20 | Снекма | Устройство и способ улавливания магнитных частиц, задержанных на магнитной пробке |
FR2957823A1 (fr) * | 2010-03-29 | 2011-09-30 | Snecma | Dispositif et procede de recuperation de particules magnetiques piegees sur un bouchon magnetique |
US9687857B2 (en) | 2010-03-29 | 2017-06-27 | Snecma | Device and method for recovering magnetic particles trapped on a magnetic plug |
CN102821865A (zh) * | 2010-03-29 | 2012-12-12 | 斯奈克玛 | 回收在磁塞上捕获的磁性颗粒的装置和方法 |
RU2553721C2 (ru) * | 2010-03-29 | 2015-06-20 | Снекма | Устройство и способ отбора магнитных частиц, захваченных магнитной пробкой |
CN102821865B (zh) * | 2010-03-29 | 2015-07-22 | 斯奈克玛 | 回收在磁塞上捕获的磁性颗粒的装置和方法 |
WO2011121207A1 (fr) * | 2010-03-29 | 2011-10-06 | Snecma | Dispositif et procede de recuperation de particules magnetiques piegees sur un bouchon magnetique |
DE102010034559A1 (de) | 2010-08-17 | 2012-02-23 | Netzsch-Feinmahltechnik Gmbh | Vorrichtung und Verfahren zum Entfernen von magnetisierbaren Verunreinigungen aus Fettmassen |
DE202011104192U1 (de) | 2010-08-17 | 2011-11-25 | Netzsch-Feinmahltechnik Gmbh | Vorrichtung zum Entfernen von magnetisierbaren Verunreinigungen aus Fettmassen |
RU2444721C1 (ru) * | 2010-11-03 | 2012-03-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Юго-Западный государственный университет" (ЮЗ ГУ) | Способ определения количества ферромагнитных частиц в потоке жидкости или газа и устройство его осуществления |
WO2012122627A1 (fr) * | 2011-03-11 | 2012-09-20 | Guisheng Yang | Dispositif et procédé de piégeage de particules magnétiques |
US8900449B2 (en) | 2012-03-13 | 2014-12-02 | Cpc Corporation, Taiwan | Magnetic filter for refining and chemical industries |
CN104471369A (zh) * | 2012-07-06 | 2015-03-25 | 株式会社日立高新技术 | 核酸提取用成套工具及核酸提取装置 |
US9650626B2 (en) | 2012-07-06 | 2017-05-16 | Hitachi High-Technologies Corporation | Kit for nucleic acid extraction and a nucleic acid extractor |
JPWO2014007074A1 (ja) * | 2012-07-06 | 2016-06-02 | 株式会社日立ハイテクノロジーズ | 磁力体カバー及び核酸抽出装置 |
WO2014007074A1 (fr) * | 2012-07-06 | 2014-01-09 | 株式会社 日立ハイテクノロジーズ | Kit d'extraction d'acides nucléiques, et extracteur d'acides nucléiques |
EP2727651A3 (fr) * | 2012-11-05 | 2017-04-26 | Hamilton Sundstrand Corporation | Système et procédé pour enlever des copeaux d'un collecteur de copeaux magnétiques |
US20230149949A1 (en) * | 2015-04-29 | 2023-05-18 | Fleenor Manufacturing, Inc. | Filter Element With Magnetic Array |
WO2017046235A1 (fr) * | 2015-09-18 | 2017-03-23 | Hamilton Bonaduz Ag | Dispositif de séparation magnétique à activation et désactivation mécanique |
DE102015218008A1 (de) * | 2015-09-18 | 2017-03-23 | Hamilton Bonaduz Ag | Magnetische Trennvorrichtung mit mechanischer Aktivierung und Deaktivierung |
EP3405288A4 (fr) * | 2016-01-19 | 2020-01-01 | Shanxi Zdgsy Bio-Scientific Co., Ltd. | Dispositif de séparation de substances biologiques multifonction |
Also Published As
Publication number | Publication date |
---|---|
SE8601143D0 (sv) | 1986-03-12 |
AU7127787A (en) | 1987-10-09 |
SE8601143L (sv) | 1987-09-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO1987005536A1 (fr) | Procede et appareil pour recueillir et disperser des particules ferromagnetiques dans un milieu fluide | |
JP5752042B2 (ja) | 磁性試薬、磁性試薬キット、磁性担体処理方法およびその処理装置 | |
US5837144A (en) | Method of magnetically separating liquid components | |
US7105357B1 (en) | Method and device for processing extremely small substance quantities | |
EP0687505B1 (fr) | Méthode de séparation magnétique pour des composants d'un liquide | |
US20100006509A1 (en) | magnetic separation apparatus | |
EP0691541B1 (fr) | Méthode pour la séparation de particules magnétiques | |
JP6332012B2 (ja) | 磁性体粒子操作用装置 | |
US20080170966A1 (en) | Flux Concentrator for Biomagnetic Particle Transfer Device | |
DE2748797A1 (de) | Vorrichtung zur verwendung in radio-immunoassays | |
ES8401636A1 (es) | Dispositivo de carga y transferencia para presentar a un analizador quimico recipientes de muestras de fluidos corporales y para retirarlos y alimentarlos seguidamente. | |
WO2007020294A1 (fr) | Dispositif et procede de separation de particules magnetiques d'un liquide | |
CH626449A5 (fr) | ||
CN108435410B (zh) | 磁性粒子操作用器件 | |
EP0995096A2 (fr) | Crayon magnetique pour la concentration et la separation de particules | |
JPH1147633A (ja) | 金属除去装置 | |
WO1990014891A1 (fr) | Dispositif separateur de particules magnetiques | |
US11766672B2 (en) | Apparatus for manipulating magnetic particles | |
US11883831B2 (en) | Magnetic particle operation device | |
Möller et al. | Improved spinning top aerosol-generator for the production of high concentrated ferrimagnetic aerosols | |
WO2016121102A1 (fr) | Dispositif de manipulation de particules magnétiques et procédé de manipulation de particules magnétiques | |
WO2004011146A1 (fr) | Dispositif et procede de manipulation de particules magnetiques | |
JPWO2018147130A1 (ja) | 磁性体粒子操作用デバイス及び磁性体粒子操作用装置 | |
DE19939208C2 (de) | Verfahren zum Darstellen von biologisch aktivierten induktivitätsändernden Partikeln zu deren Nachweis und Zählen sowie Vorrichtung dafür | |
US20200188928A1 (en) | Magnetic particle manipulating container and magnetic particle manipulating apparatus |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AU DK FI HU JP NO SU US |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): AT BE CH DE FR GB IT LU NL SE |