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WO1987001279A3 - Derives anti-tumoraux de chamigrene et leurs procedes d'utilisation - Google Patents

Derives anti-tumoraux de chamigrene et leurs procedes d'utilisation Download PDF

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Publication number
WO1987001279A3
WO1987001279A3 PCT/US1986/001746 US8601746W WO8701279A3 WO 1987001279 A3 WO1987001279 A3 WO 1987001279A3 US 8601746 W US8601746 W US 8601746W WO 8701279 A3 WO8701279 A3 WO 8701279A3
Authority
WO
WIPO (PCT)
Prior art keywords
antitumor
chamigrene
derivatives
methods
red alga
Prior art date
Application number
PCT/US1986/001746
Other languages
English (en)
Other versions
WO1987001279A2 (fr
Inventor
Kenneth M Snader
Tatsuo Higa
Original Assignee
Kenneth M Snader
Tatsuo Higa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kenneth M Snader, Tatsuo Higa filed Critical Kenneth M Snader
Publication of WO1987001279A2 publication Critical patent/WO1987001279A2/fr
Publication of WO1987001279A3 publication Critical patent/WO1987001279A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A61K31/025—Halogenated hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)

Abstract

Compositions anti-tumorales, et procédé pour inhiber, diminuer ou agir sur le développement de tumeurs ou de cellules tumorales grâce à l'utilisation des compositions anti-tumorales décrites. Plus particulièrement, les compositions anti-tumorales ci-décrites comprennent, comme ingrédient actif, une quantité effective anti-tumorale de chamigrène halogénée extraite et dérivée d'algues rouges et de mollusques qui se nourrissent d'algues rouges.
PCT/US1986/001746 1985-09-04 1986-08-22 Derives anti-tumoraux de chamigrene et leurs procedes d'utilisation WO1987001279A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/772,390 US4942180A (en) 1985-09-04 1985-09-04 Antitumor chamigrene derivatives and their methods of use
US772,390 1985-09-04

Publications (2)

Publication Number Publication Date
WO1987001279A2 WO1987001279A2 (fr) 1987-03-12
WO1987001279A3 true WO1987001279A3 (fr) 1987-07-30

Family

ID=25094903

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1986/001746 WO1987001279A2 (fr) 1985-09-04 1986-08-22 Derives anti-tumoraux de chamigrene et leurs procedes d'utilisation

Country Status (4)

Country Link
US (1) US4942180A (fr)
EP (1) EP0235261A1 (fr)
JP (1) JPS63501011A (fr)
WO (1) WO1987001279A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2211029C2 (ru) * 1994-09-09 2003-08-27 Созо КОЯМА Ингибирующие или блокирующие агенты функций молекулярной генерации и/или индукции

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986003739A1 (fr) * 1984-12-18 1986-07-03 Snader Kenneth M Derive antiviral de chamigrene

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4162309A (en) * 1978-04-10 1979-07-24 Calvin Natasha I Water soluble extracts of certain marine red algae and processes for use thereof
US4162308A (en) * 1978-04-10 1979-07-24 Calvin Natasha I Water soluble extracts of certain marine red algae and processes for use thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986003739A1 (fr) * 1984-12-18 1986-07-03 Snader Kenneth M Derive antiviral de chamigrene

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Planta Medica, Vol. 44, 1982 (Hippokrates Verlag GmbH), A.G. GONZALEZ et al., "Chemotherapeutic Activity of Polyhalogenated Terpenes from Spanish Algae", pages 44-46, see the whole document *
Tetrahedron, Vol. 35, 1979 (Pergamon Press, Ltd, Oxford, GB), M.B. HOLLENBEAK et al., "Deodactol, Antineoplastic Sesquiterpenoid from the Sea Hare Aplysia Dactylomela", pages 541-545, see page 541, left-hand column, paragraph 2 *

Also Published As

Publication number Publication date
WO1987001279A2 (fr) 1987-03-12
US4942180A (en) 1990-07-17
EP0235261A1 (fr) 1987-09-09
JPS63501011A (ja) 1988-04-14

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