TN2013000368A1 - Glucosylceramide synthase inhibitors - Google Patents
Glucosylceramide synthase inhibitorsInfo
- Publication number
- TN2013000368A1 TN2013000368A1 TNP2013000368A TN2013000368A TN2013000368A1 TN 2013000368 A1 TN2013000368 A1 TN 2013000368A1 TN P2013000368 A TNP2013000368 A TN P2013000368A TN 2013000368 A TN2013000368 A TN 2013000368A TN 2013000368 A1 TN2013000368 A1 TN 2013000368A1
- Authority
- TN
- Tunisia
- Prior art keywords
- glucosylceramide synthase
- synthase inhibitors
- treatment
- inhibitors
- glucosylceramide
- Prior art date
Links
- 239000003892 ceramide glucosyltransferase inhibitor Substances 0.000 title 1
- 102000044956 Ceramide glucosyltransferases Human genes 0.000 abstract 2
- 108091000114 ceramide glucosyltransferase Proteins 0.000 abstract 2
- 208000015439 Lysosomal storage disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000002641 enzyme replacement therapy Methods 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261590711P | 2012-01-25 | 2012-01-25 | |
| PCT/US2012/029417 WO2012129084A2 (en) | 2011-03-18 | 2012-03-16 | Glucosylceramide synthase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TN2013000368A1 true TN2013000368A1 (en) | 2015-01-20 |
Family
ID=54337514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2013000368A TN2013000368A1 (en) | 2012-01-25 | 2013-09-17 | Glucosylceramide synthase inhibitors |
Country Status (1)
| Country | Link |
|---|---|
| TN (1) | TN2013000368A1 (en) |
-
2013
- 2013-09-17 TN TNP2013000368A patent/TN2013000368A1/en unknown
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