TN2013000204A1 - Aminoalcohol substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis - Google Patents
Aminoalcohol substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesisInfo
- Publication number
- TN2013000204A1 TN2013000204A1 TNP2013000204A TN2013000204A TN2013000204A1 TN 2013000204 A1 TN2013000204 A1 TN 2013000204A1 TN P2013000204 A TNP2013000204 A TN P2013000204A TN 2013000204 A TN2013000204 A TN 2013000204A TN 2013000204 A1 TN2013000204 A1 TN 2013000204A1
- Authority
- TN
- Tunisia
- Prior art keywords
- dihydroimidazo
- diseases associated
- angiogenesis
- proliferative disorders
- derivatives useful
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 4
- NTTQCLSBWRKUIJ-UHFFFAOYSA-N 2,3-dihydroimidazo[1,2-c]quinazoline Chemical class C1=CC=C2C3=NCCN3C=NC2=C1 NTTQCLSBWRKUIJ-UHFFFAOYSA-N 0.000 title abstract 2
- 230000033115 angiogenesis Effects 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title abstract 2
- 230000003463 hyperproliferative effect Effects 0.000 title abstract 2
- 150000001414 amino alcohols Chemical group 0.000 title 1
- 208000035475 disorder Diseases 0.000 title 1
- 102000010400 1-phosphatidylinositol-3-kinase activity proteins Human genes 0.000 abstract 2
- 108091007960 PI3Ks Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
This invention relates to novel 2,3-dihydroimidazo[1,2 -c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase ( PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase ( PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2011/069637 WO2012062748A1 (en) | 2010-11-11 | 2011-11-08 | Aminoalcohol substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TN2013000204A1 true TN2013000204A1 (en) | 2014-11-10 |
Family
ID=54360704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNP2013000204A TN2013000204A1 (en) | 2011-11-08 | 2013-05-09 | Aminoalcohol substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis |
Country Status (1)
| Country | Link |
|---|---|
| TN (1) | TN2013000204A1 (en) |
-
2013
- 2013-05-09 TN TNP2013000204A patent/TN2013000204A1/en unknown
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