TN2013000257A1 - Immunosuppressant formulations - Google Patents

Immunosuppressant formulations

Info

Publication number: TN2013000257A1
Authority: TN; Tunisia
Prior art keywords: api; immunosuppressant; formulations; compound; immunosuppressant formulations
Prior art date: 2011-01-07

Application number

TNP2013000257A

Other languages

English (en)

Inventor

Philippe Bouillot

Emeric Reynaud

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-01-07

Filing date

2013-06-14

Publication date

2014-11-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44022942&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TN2013000257(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2013-06-14 Application filed by Novartis Ag filed Critical Novartis Ag

2014-11-10 Publication of TN2013000257A1 publication Critical patent/TN2013000257A1/fr

Links

238000009472 formulation Methods 0.000 title 1
229960003444 immunosuppressant agent Drugs 0.000 title 1
230000001861 immunosuppressant effect Effects 0.000 title 1
239000003018 immunosuppressive agent Substances 0.000 title 1
239000000203 mixture Substances 0.000 title 1
239000008186 active pharmaceutical agent Substances 0.000 abstract 3
150000007514 bases Chemical class 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000546 pharmaceutical excipient Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000007790 solid phase Substances 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Oncology (AREA)
Physical Education & Sports Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Communicable Diseases (AREA)
Orthopedic Medicine & Surgery (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Transplantation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

TNP2013000257A 2011-01-07 2013-06-14 Immunosuppressant formulations TN2013000257A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP11150431		2011-01-07
PCT/EP2012/050151 WO2012093161A1 (fr)	2011-01-07	2012-01-05	Formulations d'immunosuppresseurs

Publications (1)

Publication Number	Publication Date
TN2013000257A1 true TN2013000257A1 (en)	2014-11-10

Family

ID=44022942

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TNP2013000257A TN2013000257A1 (en)	2011-01-07	2013-06-14	Immunosuppressant formulations

Country Status (36)

Country	Link
US (4)	US20130273161A1 (fr)
EP (2)	EP2661261B1 (fr)
JP (2)	JP6111202B2 (fr)
KR (2)	KR102166885B1 (fr)
CN (1)	CN103458877B (fr)
AR (2)	AR084801A1 (fr)
AU (1)	AU2012204835B2 (fr)
BR (1)	BR112013017302B1 (fr)
CA (1)	CA2823616C (fr)
CL (1)	CL2013001979A1 (fr)
CO (1)	CO6761402A2 (fr)
CY (1)	CY1122182T1 (fr)
DK (1)	DK2661261T3 (fr)
EA (1)	EA026144B9 (fr)
EC (1)	ECSP13012812A (fr)
ES (1)	ES2751920T3 (fr)
GT (1)	GT201300178A (fr)
HR (1)	HRP20191842T1 (fr)
HU (1)	HUE045612T2 (fr)
IL (1)	IL227094B (fr)
JO (1)	JO3619B1 (fr)
LT (1)	LT2661261T (fr)
MA (1)	MA34897B1 (fr)
MX (2)	MX371290B (fr)
MY (1)	MY161162A (fr)
PE (1)	PE20140216A1 (fr)
PH (1)	PH12013501442B1 (fr)
PL (1)	PL2661261T3 (fr)
PT (1)	PT2661261T (fr)
SG (1)	SG191286A1 (fr)
SI (1)	SI2661261T1 (fr)
TN (1)	TN2013000257A1 (fr)
TW (2)	TWI583380B (fr)
UA (1)	UA114283C2 (fr)
WO (1)	WO2012093161A1 (fr)
ZA (1)	ZA201304465B (fr)

Families Citing this family (14)

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CN103458877B (zh)	2011-01-07	2016-06-08	诺华股份有限公司	免疫抑制性制剂
CN106456552A (zh) *	2014-04-10	2017-02-22	诺华股份有限公司	S1p调节剂的立即释放剂量方案
PT3129006T (pt) *	2014-04-10	2021-04-09	Novartis Ag	Formulação imunossupressora
CA2973540A1 (fr)	2015-02-26	2016-09-01	Novartis Ag	Traitement de maladie auto-immune chez un patient recevant en outre un betabloquant
MX378947B (es)	2015-07-03	2025-03-11	Astellas Pharma Inc	Composición farmacéutica estable para administración oral.
US11629124B2 (en)	2017-03-09	2023-04-18	Novartis Ag	Solid forms comprising an oxime ether compound, compositions and methods of use thereof
US11434200B2 (en)	2017-03-09	2022-09-06	Novartis Ag	Solid forms comprising an oxime ether compound and a coformer, compositions and methods of use thereof
CN111107837A (zh)	2017-09-27	2020-05-05	诺华股份有限公司	包含西普尼莫德的肠胃外制剂
MX2020007326A (es)	2017-09-29	2020-09-07	Novartis Ag	Regimen de dosificacion de siponimod.
MX2020007268A (es)	2017-09-29	2020-08-17	Novartis Ag	Regimen de dosificacion de siponimod.
CN109908095A (zh) *	2019-04-08	2019-06-21	肇庆学院	一种西尼莫德片剂及制备方法
WO2021214717A1 (fr)	2020-04-23	2021-10-28	Novartis Ag	Schéma posologique pour l'utilisation de siponimod pour le traitement du syndrome de détresse respiratoire aiguë
WO2023172508A1 (fr) *	2022-03-09	2023-09-14	Isp Investments Llc	Composition d'excipient co-traitée
WO2024126409A1 (fr)	2022-12-12	2024-06-20	Synthon B.V.	Composition pharmaceutique contenant du siponimod

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JP5269595B2 (ja)	2005-09-09	2013-08-21	アンジェリーニラボファームリミテッドライアビリティカンパニー	１日１回投与用トラゾドン組成物
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WO2008072056A1 (fr)	2006-12-14	2008-06-19	Pfizer Limited	Utilisation d'inhibiteurs de mtp pour traiter l'obésité au moyen de faibles doses et de doses augmentées
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KR20100021430A (ko)	2007-05-04	2010-02-24	노파르티스 아게	Ｓ1ｐ 수용체 조절제의 용도
AU2008310846C1 (en)	2007-10-12	2022-10-06	Novartis Ag	Compositions comprising sphingosine 1 phosphate (S1P) receptor modulators
US8785484B2 (en)	2008-03-17	2014-07-22	Actelion Pharmaceuticals Ltd	Dosing regimen for a selective S1P1 receptor agonist
WO2009155475A1 (fr)	2008-06-20	2009-12-23	Novartis Ag	Compositions pédiatriques pour le traitement de la sclérose en plaques
KR101608108B1 (ko)	2008-07-23	2016-03-31	노파르티스 아게	스핑고신 1 포스페이트 수용체 조절제 및 근육 염증을 치료하기 위한 그의 용도
PL2326325T3 (pl) *	2008-08-18	2015-04-30	Novartis Ag	Pochodna azetydyny do leczenia neuropatii obwodowych
ES2478842T3 (es) *	2008-12-18	2014-07-23	Novartis Ag	Sal clorhidrato del ácido 1-(4-(1-((E)-4-ciclohexil-3-trifluorometil-benziloxiimino)-etil)-2-etil-benzil)-azetidina-3-carboxílico
EP2379498B1 (fr) *	2008-12-18	2015-01-21	Novartis AG	Forme polymorphe de l' acide 1-(4-{1-[(e)-4-cyclohexyl-3-trifluorométhyl-benzyloxyimino]-éthyl}-2-éthyl-benzyl)-azétidine-3-carboxylique
PT2379497E (pt) *	2008-12-18	2013-11-29	Novartis Ag	Sal hemifumarato do ácido 1-(4-{1-[(e)-4-ciclo-hexil-3- trifluorometil-benziloxi-imino]-etil}-2-etil-benzil)- azetidina-3-carboxílico
AU2009329522B9 (en)	2008-12-19	2012-12-06	Novartis Ag	Mouthpiece for an inhaler
JP5657565B2 (ja)	2008-12-22	2015-01-21	ノバルティスアーゲー	Ｓ１ｐ受容体アゴニストの投与レジメン
NZ593065A (en)	2008-12-22	2012-11-30	Novartis Ag	Dosage regimen for a s1p receptor agonist
PH12012500520A1 (en)	2009-09-29	2012-10-22	Novartis Ag	Dosage regimen of an s1p receptor modulator
CN103458877B (zh)	2011-01-07	2016-06-08	诺华股份有限公司	免疫抑制性制剂
WO2012095853A1 (fr)	2011-01-10	2012-07-19	Novartis Pharma Ag	Formulations à libération modifiée comprenant des modulateurs des récepteurs sip
TW201320994A (zh)	2011-10-11	2013-06-01	Novartis Ag	投藥療程
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PT3129006T (pt)	2014-04-10	2021-04-09	Novartis Ag	Formulação imunossupressora

2012
- 2012-01-05 CN CN201280004869.2A patent/CN103458877B/zh active Active
- 2012-01-05 LT LT12700262T patent/LT2661261T/lt unknown
- 2012-01-05 DK DK12700262.4T patent/DK2661261T3/da active
- 2012-01-05 HU HUE12700262A patent/HUE045612T2/hu unknown
- 2012-01-05 EP EP12700262.4A patent/EP2661261B1/fr active Active
- 2012-01-05 UA UAA201307576A patent/UA114283C2/uk unknown
- 2012-01-05 JP JP2013547861A patent/JP6111202B2/ja active Active
- 2012-01-05 BR BR112013017302-5A patent/BR112013017302B1/pt active IP Right Grant
- 2012-01-05 KR KR1020197004860A patent/KR102166885B1/ko active Active
- 2012-01-05 WO PCT/EP2012/050151 patent/WO2012093161A1/fr active Application Filing
- 2012-01-05 JO JOP/2012/0005A patent/JO3619B1/ar active
- 2012-01-05 KR KR1020137020755A patent/KR101951966B1/ko active Active
- 2012-01-05 PH PH1/2013/501442A patent/PH12013501442B1/en unknown
- 2012-01-05 MA MA36170A patent/MA34897B1/fr unknown
- 2012-01-05 SI SI201231683T patent/SI2661261T1/sl unknown
- 2012-01-05 SG SG2013047923A patent/SG191286A1/en unknown
- 2012-01-05 PL PL12700262T patent/PL2661261T3/pl unknown
- 2012-01-05 EP EP19188018.6A patent/EP3590507A1/fr active Pending
- 2012-01-05 PT PT127002624T patent/PT2661261T/pt unknown
- 2012-01-05 MX MX2017007300A patent/MX371290B/es unknown
- 2012-01-05 CA CA2823616A patent/CA2823616C/fr active Active
- 2012-01-05 PE PE2013001522A patent/PE20140216A1/es active IP Right Grant
- 2012-01-05 EA EA201391018A patent/EA026144B9/ru active Protection Beyond IP Right Term
- 2012-01-05 AU AU2012204835A patent/AU2012204835B2/en active Active
- 2012-01-05 ES ES12700262T patent/ES2751920T3/es active Active
- 2012-01-05 MX MX2013007909A patent/MX357304B/es active IP Right Grant
- 2012-01-06 MY MYPI2013002251A patent/MY161162A/en unknown
- 2012-01-06 AR ARP120100047A patent/AR084801A1/es not_active Application Discontinuation
- 2012-01-06 TW TW104142389A patent/TWI583380B/zh active
- 2012-01-06 TW TW101100702A patent/TWI610672B/zh active
2013
- 2013-06-14 TN TNP2013000257A patent/TN2013000257A1/fr unknown
- 2013-06-14 US US13/917,730 patent/US20130273161A1/en not_active Abandoned
- 2013-06-18 ZA ZA2013/04465A patent/ZA201304465B/en unknown
- 2013-06-20 IL IL227094A patent/IL227094B/en active IP Right Grant
- 2013-07-05 GT GT201300178A patent/GT201300178A/es unknown
- 2013-07-05 CL CL2013001979A patent/CL2013001979A1/es unknown
- 2013-07-16 CO CO13168667A patent/CO6761402A2/es unknown
- 2013-08-07 EC ECSP13012812 patent/ECSP13012812A/es unknown
2017
- 2017-03-13 JP JP2017047220A patent/JP6324569B2/ja active Active
2019
- 2019-10-11 HR HRP20191842TT patent/HRP20191842T1/hr unknown
- 2019-10-22 CY CY20191101097T patent/CY1122182T1/el unknown
2020
- 2020-02-28 US US16/804,926 patent/US20200199069A1/en not_active Abandoned
2021
- 2021-04-14 US US17/230,175 patent/US12071402B2/en active Active
2022
- 2022-01-17 AR ARP220100086A patent/AR124662A2/es unknown
2024
- 2024-08-13 US US18/802,089 patent/US20250084034A1/en active Pending

Also Published As

Publication number	Publication date
KR20190025727A (ko)	2019-03-11
PE20140216A1 (es)	2014-03-01
MX2013007909A (es)	2013-08-29
JO3619B1 (ar)	2020-08-27
CY1122182T1 (el)	2020-11-25
JP6324569B2 (ja)	2018-05-16
CN103458877A (zh)	2013-12-18
AU2012204835B2 (en)	2015-07-09
KR20140037815A (ko)	2014-03-27
US20200199069A1 (en)	2020-06-25
PT2661261T (pt)	2019-10-25
SI2661261T1 (sl)	2019-11-29
US12071402B2 (en)	2024-08-27
JP2017141248A (ja)	2017-08-17
US20220064110A1 (en)	2022-03-03
MA34897B1 (fr)	2014-02-01
CN103458877B (zh)	2016-06-08
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ZA201304465B (en)	2014-02-26
LT2661261T (lt)	2019-10-25
EA026144B9 (ru)	2021-10-26
GT201300178A (es)	2014-12-30
PH12013501442A1 (en)	2013-09-09
US20130273161A1 (en)	2013-10-17
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DK2661261T3 (da)	2019-10-21
EP2661261A1 (fr)	2013-11-13
KR102166885B1 (ko)	2020-10-19
BR112013017302A2 (pt)	2016-10-25
AR084801A1 (es)	2013-06-26
TWI610672B (zh)	2018-01-11
HRP20191842T1 (hr)	2019-12-27
NZ612420A (en)	2015-05-29
CO6761402A2 (es)	2013-09-30
CA2823616A1 (fr)	2012-07-12
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JP6111202B2 (ja)	2017-04-05
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TWI583380B (zh)	2017-05-21
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MX357304B (es)	2018-07-04
UA114283C2 (uk)	2017-05-25
MY161162A (en)	2017-04-14
IL227094B (en)	2019-03-31
EP2661261B1 (fr)	2019-07-31
EA201391018A1 (ru)	2013-11-29
PH12013501442B1 (en)	2018-04-20
AR124662A2 (es)	2023-04-19
TW201249438A (en)	2012-12-16
KR101951966B1 (ko)	2019-02-25
BR112013017302B1 (pt)	2021-12-07
PL2661261T3 (pl)	2020-01-31
TW201609092A (zh)	2016-03-16
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US20250084034A1 (en)	2025-03-13

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