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TN2012000267A1 - Nouveaux derives azabicyclo [3.1.0] hex- 2 -yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent - Google Patents

Nouveaux derives azabicyclo [3.1.0] hex- 2 -yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Info

Publication number
TN2012000267A1
TN2012000267A1 TNP2012000267A TN2012000267A TN2012000267A1 TN 2012000267 A1 TN2012000267 A1 TN 2012000267A1 TN P2012000267 A TNP2012000267 A TN P2012000267A TN 2012000267 A TN2012000267 A TN 2012000267A TN 2012000267 A1 TN2012000267 A1 TN 2012000267A1
Authority
TN
Tunisia
Prior art keywords
hex
derivatives
preparing
pharmaceutical compositions
compositions containing
Prior art date
Application number
TNP2012000267A
Other languages
English (en)
Inventor
Patrick Gasara
Anne-Marie Chollet
Alain Dhainaut
Jean-Michel Henlin
Pierre Lestage
Fany Panayi
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42711699&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TN2012000267(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Servier Lab filed Critical Servier Lab
Publication of TN2012000267A1 publication Critical patent/TN2012000267A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Composés de formule (I) : dans laquelle : ALK représente une chaîne alkylène, W représente un groupement de formule (II) ou de formule (III) où R et R' sont tels que définis dans la description. Médicament.
TNP2012000267A 2009-12-09 2012-05-28 Nouveaux derives azabicyclo [3.1.0] hex- 2 -yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent TN2012000267A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0905953A FR2953521B1 (fr) 2009-12-09 2009-12-09 Nouveaux derives azabicyclo[3.1.0]hex-2-yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2010/000823 WO2011070253A1 (fr) 2009-12-09 2010-12-08 Derives azabicyclo [3.1.0] hex- 2 -yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
TN2012000267A1 true TN2012000267A1 (fr) 2013-12-12

Family

ID=42711699

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2012000267A TN2012000267A1 (fr) 2009-12-09 2012-05-28 Nouveaux derives azabicyclo [3.1.0] hex- 2 -yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Country Status (32)

Country Link
US (1) US20120283245A1 (fr)
EP (1) EP2509947A1 (fr)
JP (1) JP2013513589A (fr)
KR (1) KR20120102763A (fr)
CN (1) CN102652127A (fr)
AP (1) AP2012006352A0 (fr)
AR (1) AR079265A1 (fr)
AU (1) AU2010329762B2 (fr)
BR (1) BR112012013666A2 (fr)
CA (1) CA2782469C (fr)
CL (1) CL2012001479A1 (fr)
CO (1) CO6541535A2 (fr)
CR (1) CR20120286A (fr)
CU (1) CU20120091A7 (fr)
EA (1) EA201200849A1 (fr)
EC (1) ECSP12011950A (fr)
FR (1) FR2953521B1 (fr)
GE (1) GEP20156227B (fr)
IN (1) IN2012DN04966A (fr)
MA (1) MA33882B1 (fr)
MX (1) MX2012006578A (fr)
NI (1) NI201200099A (fr)
PE (1) PE20121475A1 (fr)
PH (1) PH12012501053A1 (fr)
SA (1) SA110320011B1 (fr)
SG (1) SG181082A1 (fr)
TN (1) TN2012000267A1 (fr)
TW (1) TW201200499A (fr)
UA (1) UA102950C2 (fr)
UY (1) UY33072A (fr)
WO (1) WO2011070253A1 (fr)
ZA (1) ZA201203943B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160048930A (ko) * 2013-09-09 2016-05-04 사노피 알츠하이머 질환의 치료에 사용하기 위해 콜린에스테라제 저해제와 조합된 h3 수용체 길항제

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2866647B1 (fr) * 2004-02-20 2006-10-27 Servier Lab Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB0507680D0 (en) * 2005-04-15 2005-05-25 Glaxo Group Ltd Compounds
ES2342979T3 (es) * 2005-11-30 2010-07-20 F. Hoffmann-La Roche Ag Derivados de indol-2-carboxamida sustituidos en 5.

Also Published As

Publication number Publication date
PH12012501053A1 (en) 2013-02-04
SG181082A1 (en) 2012-07-30
ECSP12011950A (es) 2012-07-31
CO6541535A2 (es) 2012-10-16
AU2010329762B2 (en) 2013-10-03
AU2010329762A1 (en) 2012-06-21
SA110320011B1 (ar) 2013-10-01
KR20120102763A (ko) 2012-09-18
ZA201203943B (en) 2013-08-28
IN2012DN04966A (fr) 2015-09-25
CU20120091A7 (es) 2012-07-31
TW201200499A (en) 2012-01-01
WO2011070253A1 (fr) 2011-06-16
PE20121475A1 (es) 2012-10-20
UA102950C2 (ru) 2013-08-27
WO2011070253A8 (fr) 2012-08-02
FR2953521A1 (fr) 2011-06-10
CA2782469A1 (fr) 2011-06-16
CA2782469C (fr) 2014-04-08
CL2012001479A1 (es) 2013-02-08
MX2012006578A (es) 2012-06-25
BR112012013666A2 (pt) 2016-04-19
MA33882B1 (fr) 2013-01-02
US20120283245A1 (en) 2012-11-08
GEP20156227B (en) 2015-01-26
FR2953521B1 (fr) 2011-11-18
NI201200099A (es) 2012-11-09
EP2509947A1 (fr) 2012-10-17
EA201200849A1 (ru) 2013-01-30
AP2012006352A0 (en) 2012-08-31
CN102652127A (zh) 2012-08-29
JP2013513589A (ja) 2013-04-22
AR079265A1 (es) 2012-01-04
UY33072A (es) 2011-05-31
CR20120286A (es) 2012-08-20

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