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TN2011000610A1 - 2,4-diaminopyrimidines for the treatment of diseases characterised b y excessive or abnormal cell proliferation - Google Patents

2,4-diaminopyrimidines for the treatment of diseases characterised b y excessive or abnormal cell proliferation

Info

Publication number
TN2011000610A1
TN2011000610A1 TNP2011000610A TN2011000610A TN2011000610A1 TN 2011000610 A1 TN2011000610 A1 TN 2011000610A1 TN P2011000610 A TNP2011000610 A TN P2011000610A TN 2011000610 A TN2011000610 A TN 2011000610A TN 2011000610 A1 TN2011000610 A1 TN 2011000610A1
Authority
TN
Tunisia
Prior art keywords
excessive
treatment
cell proliferation
abnormal cell
diaminopyrimidines
Prior art date
Application number
TNP2011000610A
Inventor
Loannis Sapountzis
Heinz Stadtmueller
Daniel Kuhn
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2010/057408 external-priority patent/WO2010136559A1/en
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of TN2011000610A1 publication Critical patent/TN2011000610A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention encompasses compounds of general formula (1), wherein A, B, R1 to R5, Rx m, n and p are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, pharmaceutical preparations which contain such compounds and the use thereof [as] medicaments.
TNP2011000610A 2009-05-29 2011-11-28 2,4-diaminopyrimidines for the treatment of diseases characterised b y excessive or abnormal cell proliferation TN2011000610A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09161496 2009-05-29
PCT/EP2010/057408 WO2010136559A1 (en) 2009-05-29 2010-05-28 2, 4 -diaminopyrimidines for the treatment of diseases characterised by excessive or abnormal cell proliferation

Publications (1)

Publication Number Publication Date
TN2011000610A1 true TN2011000610A1 (en) 2013-05-24

Family

ID=41138982

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2011000610A TN2011000610A1 (en) 2009-05-29 2011-11-28 2,4-diaminopyrimidines for the treatment of diseases characterised b y excessive or abnormal cell proliferation

Country Status (1)

Country Link
TN (1) TN2011000610A1 (en)

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