TN2009000398A1 - 5,6-dihydro-1h-pyridin-2-one compounds - Google Patents

5,6-dihydro-1h-pyridin-2-one compounds

Info

Publication number: TN2009000398A1
Authority: TN; Tunisia
Prior art keywords: compounds; pyridin; dihydro; hepatitis; virus
Prior art date: 2007-04-03

Application number

TNP2009000398A

Other languages

English (en)

Inventor

Chinh Viet Tran

Frank Ruebsam

Douglas Eric Murphy

Peter DRAGOVICH

Yuefen Zhou

Lijian Chen

David Kucera

Fritz Blatter

Martin Viertelhaus

Original Assignee

Anadys Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-04-03

Filing date

2009-09-30

Publication date

2010-12-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39831340&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TN2009000398(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-09-30 Application filed by Anadys Pharmaceuticals Inc filed Critical Anadys Pharmaceuticals Inc

2010-12-31 Publication of TN2009000398A1 publication Critical patent/TN2009000398A1/fr

Links

OXRRHYRRQWIHIV-UHFFFAOYSA-N 2,3-dihydro-1h-pyridin-6-one Chemical class O=C1NCCC=C1 OXRRHYRRQWIHIV-UHFFFAOYSA-N 0.000 title abstract 2
241000711549 Hepacivirus C Species 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/18—Bridged systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Psychology (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Materials For Medical Uses (AREA)

TNP2009000398A 2007-04-03 2009-09-30 5,6-dihydro-1h-pyridin-2-one compounds TN2009000398A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US90747807P	2007-04-03	2007-04-03
PCT/US2008/059164 WO2008124450A1 (fr)	2007-04-03	2008-04-02	Composés de 5,6-dihydro-1h-pyridine-2-un

Publications (1)

Publication Number	Publication Date
TN2009000398A1 true TN2009000398A1 (en)	2010-12-31

Family

ID=39831340

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TNP2009000398A TN2009000398A1 (en)	2007-04-03	2009-09-30	5,6-dihydro-1h-pyridin-2-one compounds

Country Status (23)

Country	Link
US (6)	US7939524B2 (fr)
EP (1)	EP2129224B1 (fr)
JP (2)	JP5739662B2 (fr)
KR (1)	KR101542516B1 (fr)
CN (2)	CN101677563B (fr)
AR (1)	AR065927A1 (fr)
AU (1)	AU2008237364B2 (fr)
BR (1)	BRPI0809685A2 (fr)
CA (1)	CA2682584C (fr)
CL (1)	CL2008000959A1 (fr)
EA (1)	EA017685B1 (fr)
ES (1)	ES2578302T3 (fr)
HK (2)	HK1137119A1 (fr)
IL (2)	IL201312A (fr)
MX (1)	MX2009010564A (fr)
MY (1)	MY157961A (fr)
NZ (1)	NZ580445A (fr)
PE (1)	PE20090220A1 (fr)
TN (1)	TN2009000398A1 (fr)
TW (2)	TWI481588B (fr)
UA (1)	UA100120C2 (fr)
WO (1)	WO2008124450A1 (fr)
ZA (1)	ZA200907673B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5306194B2 (ja)	2006-06-22	2013-10-02	アナディスファーマシューティカルズインク	ピロ［１，２−ｂ］ピリダジノン化合物
UA100120C2 (en)	2007-04-03	2012-11-26	Анадис Фармасьютикалз, Инк.	5,6-dihydro-1h-pyridin-2-one compounds
WO2009152166A1 (fr) *	2008-06-10	2009-12-17	Anadys Pharmaceuticals, Inc.	Composés de dioxyde-1,1 de thiadiazine[1,2,4]
WO2010042834A1 (fr)	2008-10-09	2010-04-15	Anadys Pharmaceuticals, Inc.	Procédé d'inhibition du virus de l'hépatite c par combinaison d'une 5,6-dihydro-1h-pyridin-2-one et d'un ou plusieurs composés antiviraux supplémentaires
TW201026675A (en) *	2008-10-09	2010-07-16	Anadys Pharmaceuticals Inc	5,6-dihydro-1H-pyridin-2-one compounds
KR20120092142A (ko)	2009-10-28	2012-08-20	애나디스 파마슈티칼스, 인코포레이티드	중수소화 5,6-다이하이드로-1ｈ-파이리딘-2-온 화합물
PH12012501216A1 (en)	2009-12-18	2012-11-05	Boehringer Ingelheim Int	Hcv combination therapy
US20120321590A1 (en)	2011-04-06	2012-12-20	Anadys Pharmaceuticals, Inc.	Bridged polycyclic compounds
US8815847B2 (en) *	2011-06-07	2014-08-26	Anadys Pharmaceuticals, Inc.	[1,2,4]thiadiazine 1,1-dioxide compounds for lowering serum uric acid
CN104812383A (zh) *	2012-06-12	2015-07-29	豪夫迈·罗氏有限公司	治疗hcv感染的治疗剂组合
CN105051010B (zh) *	2013-01-14	2017-07-28	豪夫迈·罗氏有限公司	制备n‑(4‑硝基‑2‑氨磺酰基‑苯基)‑丙酰胺酸甲酯和n‑(4‑氨基‑2‑氨磺酰基‑苯基)‑丙酰胺酸甲酯的新方法
SI3421468T1 (sl) *	2013-11-13	2021-03-31	Vertex Pharmaceuticals Incorporated	Postopki za pripravo inhibitorjev replikacije virusov influence
WO2016130043A1 (fr) *	2015-02-13	2016-08-18	Александ Васильевич ИВАЩЕНКО	Inhibiteurs de réplication du virus de l'hépatite b à base de benzo[1,2,4]thiadiazine et compositions pharmaceutiques pour traiter l'hépatite b
US20180126000A1 (en)	2016-06-02	2018-05-10	Abbvie Inc.	Glucocorticoid receptor agonist and immunoconjugates thereof
WO2019106609A1 (fr)	2017-12-01	2019-06-06	Abbvie Inc.	Agoniste du récepteur des glucocorticoïdes et immunoconjugués de celui-ci
CA3137584A1 (fr)	2019-04-29	2020-11-05	Solent Therapeutics, Llc	Derives de 1,1-dioxyde de 3-amino-4h-benzo[e][1,2,4]thiadiazine en tant qu'inhibiteurs de mrgx2
CN113292574B (zh) *	2020-02-21	2022-05-03	四川大学	一类手性多环的托品烷化合物及其制备方法和用途
US12274700B1 (en)	2020-10-30	2025-04-15	Accencio LLC	Methods of treating symptoms of coronavirus infection with RNA polymerase inhibitors
JP7435515B2 (ja) *	2021-03-17	2024-02-21	株式会社村田製作所	部品収容装置

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4171361A (en) *	1977-03-31	1979-10-16	Eli Lilly And Company	1-Substituted-3-amino-6,7-dialkoxy-1H-1,2,4-benzothiadiazine-1-oxides
US4889851A (en) *	1986-11-21	1989-12-26	Fujisawa Pharmaceutical Co, Ltd.	Benzothiadiazine compounds, and pharmaceutical composition comprising the same
AU2001261377A1 (en)	2000-05-10	2001-11-20	Smith Kline Beecham Corporation	Novel anti-infectives
AR036081A1 (es)	2001-06-07	2004-08-11	Smithkline Beecham Corp	Compuesto de 1,2-dihidroquinolina, su uso para preparar una composicion farmaceutica, metodos para prepararlo y compuestos del acido 2-aminobenzoico n-alquilado de utilidad como intermediarios en dichos metodos
WO2003059356A2 (fr)	2001-10-30	2003-07-24	Smithkline Beecham Corporation	Nouveaux anti-infectieux
CA2504385C (fr)	2002-11-01	2012-12-18	Abbott Laboratories	Agents anti-infectieux
DE60335564D1 (de) *	2002-11-01	2011-02-10	Abbott Lab	Antiinfektiöse mittel
US20050075331A1 (en) *	2003-10-06	2005-04-07	Pratt John K.	Anti-infective agents
US7601709B2 (en)	2003-02-07	2009-10-13	Enanta Pharmaceuticals, Inc.	Macrocyclic hepatitis C serine protease inhibitors
ES2378071T3 (es) *	2004-03-24	2012-04-04	Janssen Pharmaceutica Nv	Moduladores de cannabinoides de tetrahidro-indazol
US7439246B2 (en)	2004-06-28	2008-10-21	Bristol-Myers Squibb Company	Fused heterocyclic kinase inhibitors
DE602005015732D1 (de)	2004-08-23	2009-09-10	Hoffmann La Roche	Heterozyklische antivirale verbindungen
GT200500373A (es)	2004-12-17	2006-10-02		Compuestos de piridazinones
WO2006093801A1 (fr) *	2005-02-25	2006-09-08	Abbott Laboratories	Derives de thiadiazine utiles en tant qu’agents anti-infectieux
BRPI0607533A2 (pt)	2005-04-21	2009-09-15	Nippon Shinyaku Co Ltd	derivado de ftalazinona, composição farmacêutica, inibidor de fosfodiesterase do tipo 4,supressor da produção de tnf-alfa, agente preventivo ou terapêutico, preparado externo, bem como uso do referido derivado
MX2007013415A (es)	2005-05-04	2008-01-15	Hoffmann La Roche	Compuestos antivirales heterociclicos.
WO2008051637A2 (fr)	2006-06-22	2008-05-02	Anadys Pharmaceuticals, Inc.	Composés de pyridazinone
JP5306194B2 (ja) *	2006-06-22	2013-10-02	アナディスファーマシューティカルズインク	ピロ［１，２−ｂ］ピリダジノン化合物
TW200840572A (en) *	2006-12-12	2008-10-16	Anadys Pharmaceuticals Inc	5,6-dihydro-1H-pyridin-2-one compounds
WO2008073987A1 (fr)	2006-12-12	2008-06-19	Anadys Pharmaceuticals, Inc.	Composés [1,2-b]pyridazinone condensés saturés
US20080188466A1 (en)	2006-12-21	2008-08-07	Anadys Pharmaceuticals, Inc.	Pyridazinone compounds
WO2008082725A1 (fr)	2006-12-29	2008-07-10	Anadys Pharmaceuticals, Inc.	Composés de type pyridazinone
US20080227774A1 (en)	2007-03-15	2008-09-18	Frank Ruebsam	5,5-disubstituted-indolizinone compounds
UA100120C2 (en)	2007-04-03	2012-11-26	Анадис Фармасьютикалз, Инк.	5,6-dihydro-1h-pyridin-2-one compounds
US7834009B2 (en) *	2007-08-27	2010-11-16	Anadys Pharmaceuticals, Inc.	4-hydroxy-5,6-dihydro-1H-pyridin-2-one compounds

2008
- 2008-02-04 UA UAA200910844A patent/UA100120C2/ru unknown
- 2008-04-02 WO PCT/US2008/059164 patent/WO2008124450A1/fr active Application Filing
- 2008-04-02 PE PE2008000597A patent/PE20090220A1/es active IP Right Grant
- 2008-04-02 ES ES08733076.7T patent/ES2578302T3/es active Active
- 2008-04-02 EP EP08733076.7A patent/EP2129224B1/fr active Active
- 2008-04-02 CL CL2008000959A patent/CL2008000959A1/es unknown
- 2008-04-02 BR BRPI0809685A patent/BRPI0809685A2/pt not_active Application Discontinuation
- 2008-04-02 AU AU2008237364A patent/AU2008237364B2/en not_active Ceased
- 2008-04-02 JP JP2010502271A patent/JP5739662B2/ja not_active Expired - Fee Related
- 2008-04-02 NZ NZ580445A patent/NZ580445A/en not_active IP Right Cessation
- 2008-04-02 KR KR1020097023036A patent/KR101542516B1/ko not_active Expired - Fee Related
- 2008-04-02 MY MYPI20094109A patent/MY157961A/en unknown
- 2008-04-02 CA CA2682584A patent/CA2682584C/fr active Active
- 2008-04-02 TW TW103101356A patent/TWI481588B/zh not_active IP Right Cessation
- 2008-04-02 CN CN200880018225.2A patent/CN101677563B/zh not_active Expired - Fee Related
- 2008-04-02 CN CN201410217806.6A patent/CN104086540B/zh not_active Expired - Fee Related
- 2008-04-02 EA EA200970916A patent/EA017685B1/ru unknown
- 2008-04-02 TW TW097111924A patent/TWI427079B/zh not_active IP Right Cessation
- 2008-04-02 US US12/061,499 patent/US7939524B2/en active Active
- 2008-04-02 MX MX2009010564A patent/MX2009010564A/es active IP Right Grant
- 2008-04-03 AR ARP080101383A patent/AR065927A1/es active IP Right Grant
2009
- 2009-09-30 TN TNP2009000398A patent/TN2009000398A1/fr unknown
- 2009-10-01 IL IL201312A patent/IL201312A/en active IP Right Grant
- 2009-11-02 ZA ZA2009/07673A patent/ZA200907673B/en unknown
2010
- 2010-05-13 HK HK10104667.2A patent/HK1137119A1/zh not_active IP Right Cessation
2011
- 2011-03-08 US US13/043,167 patent/US8101800B2/en not_active Expired - Fee Related
2012
- 2012-01-23 US US13/356,063 patent/US8236948B2/en not_active Expired - Fee Related
- 2012-08-06 US US13/567,667 patent/US8546602B2/en active Active
2013
- 2013-04-11 IL IL225694A patent/IL225694A/en active IP Right Grant
- 2013-09-30 US US14/041,376 patent/US8765741B2/en active Active
2014
- 2014-06-10 US US14/300,306 patent/US9156832B2/en not_active Expired - Fee Related
2015
- 2015-02-10 HK HK15101490.6A patent/HK1201822A1/xx not_active IP Right Cessation
- 2015-02-16 JP JP2015027744A patent/JP5934403B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
MX2009010564A (es)	2009-10-26
EP2129224A1 (fr)	2009-12-09
US8546602B2 (en)	2013-10-01
US20100034773A1 (en)	2010-02-11
CL2008000959A1 (es)	2008-11-03
US7939524B2 (en)	2011-05-10
PE20090220A1 (es)	2009-03-12
EA017685B1 (ru)	2013-02-28
EA200970916A1 (ru)	2010-04-30
US9156832B2 (en)	2015-10-13
ZA200907673B (en)	2014-04-30
EP2129224B1 (fr)	2016-03-30
JP5934403B2 (ja)	2016-06-15
TWI427079B (zh)	2014-02-21
HK1201822A1 (en)	2015-09-11
ES2578302T3 (es)	2016-07-22
AU2008237364A1 (en)	2008-10-16
US20150065492A1 (en)	2015-03-05
IL201312A0 (en)	2010-05-31
CN104086540B (zh)	2017-04-12
US20140031346A1 (en)	2014-01-30
US8101800B2 (en)	2012-01-24
TWI481588B (zh)	2015-04-21
JP2010523586A (ja)	2010-07-15
TW201431830A (zh)	2014-08-16
JP5739662B2 (ja)	2015-06-24
KR101542516B1 (ko)	2015-08-06
CA2682584C (fr)	2017-03-14
AR065927A1 (es)	2009-07-08
AU2008237364B2 (en)	2014-03-06
WO2008124450A1 (fr)	2008-10-16
IL225694A (en)	2016-08-31
HK1137119A1 (zh)	2010-07-23
US8765741B2 (en)	2014-07-01
US20120130068A1 (en)	2012-05-24
BRPI0809685A2 (pt)	2016-09-27
CN101677563A (zh)	2010-03-24
UA100120C2 (en)	2012-11-26
CN104086540A (zh)	2014-10-08
NZ580445A (en)	2012-01-12
KR20090127437A (ko)	2009-12-11
EP2129224A4 (fr)	2011-01-05
US8236948B2 (en)	2012-08-07
CN101677563B (zh)	2014-06-25
IL201312A (en)	2015-05-31
IL225694A0 (en)	2013-06-27
CA2682584A1 (fr)	2008-10-16
US20110166344A1 (en)	2011-07-07
MY157961A (en)	2016-08-30
JP2015134783A (ja)	2015-07-27
US20120302744A1 (en)	2012-11-29
TW200906829A (en)	2009-02-16

Publication	Publication Date	Title
TN2009000398A1 (en)	2010-12-31	5,6-dihydro-1h-pyridin-2-one compounds
TW200635596A (en)	2006-10-16	Pyridazinone compounds
WO2008073982A3 (fr)	2008-07-31	Composés de 5,6-dihydro-1h-pyridine-2-one
HK1123733A1 (en)	2009-06-26	Viral hepatitis treatment
WO2007150001A8 (fr)	2008-02-28	Composés de la pyrro[1,2-b]pyridazinone
MX2009006846A (es)	2009-08-20	Derivados de tetraciclina para el tratamiento de infecciones bacterianas, virales y parasitarias.
WO2008127364A3 (fr)	2008-12-18	Composés antiviraux et utilisation de ceux-ci
EA201390538A1 (ru)	2014-02-28	Противовирусные соединения
MX2009004556A (es)	2009-07-10	Inhibidores de la proteasa ns3 del hcv.
WO2008115281A3 (fr)	2008-12-04	Composés de traitement d'infections virales
CO6190510A2 (es)	2010-08-19	Inhibidores del virus de la hepatitis c
MY152070A (en)	2014-08-15	Macrocyclic quinxaline compounds as hcv ns3 protease inhibitors
ATE551337T1 (de)	2012-04-15	Inhibitoren des hepatitis-c-virus
MX2011006631A (es)	2011-09-06	Inhibidores de proteasa ns3 del virus hcv.
IL196815A0 (en)	2009-11-18	Hepatitis c virus inhibitors
MX2010008749A (es)	2010-08-31	Inhibidores del virus de la hepatitis c.
WO2008144500A3 (fr)	2010-06-10	Dérivés d'oxyde de 1-méthyl-benzo[1,2,4]thiadizine
MX2010001416A (es)	2010-03-01	Compuesto para el tratamiento de la hepatitis c.
WO2011160024A3 (fr)	2013-07-18	Composés utiles en tant qu'agents antiviraux, compositions, et procédés d'utilisation
CL2009000119A1 (es)	2010-03-05	Compuestos derivados de amino-bencimidazoles sustituidos; composicion farmaceutica; y su uso en el tratamiento del alzheimer.
CL2007002671A1 (es)	2008-04-18	Compuestos derivados de octahidro-pirrolo[3,4-c]pirrol; composicion farmaceutica que la comprende; y uso del compuesto en el tratamiento del vih, sida o arc.
CL2008000629A1 (es)	2008-08-29	Compuestos macrociclicos derivados de 6-aril-4-mercapto-[1.3.5]triazina/[1.3]pirimidin-2-amina; composicion farmaceutica, utiles en el tratamiento del cancer.
TN2011000204A1 (en)	2012-12-17	Cycloundecadepsipeptide compounds and use of said compounds as a medicament
WO2008051637A3 (fr)	2008-08-28	Composés de pyridazinone
CL2008003602A1 (es)	2009-10-09	Compuestos derivados de triazolotriazinas y triazolopirazinas sustituidas; composicion farmaceutica; y su uso en el tratamiento y/o profilaxis de trastornos hematologicos.