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TN2009000181A1 - Agonist trkb antibodies and uses thereof - Google Patents

Agonist trkb antibodies and uses thereof

Info

Publication number
TN2009000181A1
TN2009000181A1 TNP2009000181A TN2009000181A TN2009000181A1 TN 2009000181 A1 TN2009000181 A1 TN 2009000181A1 TN P2009000181 A TNP2009000181 A TN P2009000181A TN 2009000181 A TN2009000181 A TN 2009000181A TN 2009000181 A1 TN2009000181 A1 TN 2009000181A1
Authority
TN
Tunisia
Prior art keywords
trkb antibodies
agonist
agonist trkb
antibodies
methods
Prior art date
Application number
TNP2009000181A
Other languages
English (en)
Inventor
Yan Wang
Steven B Cohen
Marc Nasoff
Original Assignee
Irm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Irm Llc filed Critical Irm Llc
Publication of TN2009000181A1 publication Critical patent/TN2009000181A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TNP2009000181A 2006-11-09 2009-05-08 Agonist trkb antibodies and uses thereof TN2009000181A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85816906P 2006-11-09 2006-11-09
PCT/US2007/083774 WO2008058127A2 (fr) 2006-11-09 2007-11-06 Anticorps d'agonistes de trkb et leurs utilisations

Publications (1)

Publication Number Publication Date
TN2009000181A1 true TN2009000181A1 (en) 2010-10-18

Family

ID=39365312

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2009000181A TN2009000181A1 (en) 2006-11-09 2009-05-08 Agonist trkb antibodies and uses thereof

Country Status (27)

Country Link
US (1) US20100150914A1 (fr)
EP (1) EP2087007A2 (fr)
JP (1) JP2010509354A (fr)
KR (1) KR20090088896A (fr)
CN (1) CN101573381A (fr)
AR (1) AR063640A1 (fr)
AU (1) AU2007316418A1 (fr)
BR (1) BRPI0719000A2 (fr)
CA (1) CA2669205A1 (fr)
CL (1) CL2007003236A1 (fr)
CO (1) CO6180432A2 (fr)
CR (1) CR10779A (fr)
DO (1) DOP2009000102A (fr)
EA (1) EA200970469A1 (fr)
EC (1) ECSP099392A (fr)
IL (1) IL198468A0 (fr)
MA (1) MA30922B1 (fr)
MX (1) MX2009004881A (fr)
NI (1) NI200900081U (fr)
NO (1) NO20092217L (fr)
PE (1) PE20081168A1 (fr)
RU (1) RU2009121641A (fr)
SM (1) SMAP200900040A (fr)
TN (1) TN2009000181A1 (fr)
TW (1) TW200829270A (fr)
WO (1) WO2008058127A2 (fr)
ZA (1) ZA200902943B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100089851A (ko) * 2007-10-23 2010-08-12 노파르티스 아게 호흡기 질환의 치료를 위한 ｔｒｋｂ 항체의 용도
TW200936608A (en) 2008-01-17 2009-09-01 Irm Llc Improved anti-TrkB antibodies
WO2010106187A2 (fr) * 2009-03-20 2010-09-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Inhibiteurs de cathepsine s pour la prévention ou le traitement de troubles associés à l'obésité
GB2491106A (en) * 2011-05-18 2012-11-28 Univ Basel Antibodies against tropomyosin-related kinase B receptors
CN104244981A (zh) * 2011-12-09 2014-12-24 诺和诺德A/S Glp-1激动剂
CN102944674B (zh) * 2012-11-05 2014-10-22 武汉远征世纪制药有限公司 一种检测TrkB受体pan-Tyr位点活性的ELISA试剂盒及其使用方法
CN102901815B (zh) * 2012-11-05 2014-10-22 武汉远征世纪制药有限公司 一种检测TrkB受体816/817位酪氨酸位点活性的ELISA试剂盒及其使用方法
WO2015173756A2 (fr) 2014-05-16 2015-11-19 Pfizer Inc. Anticorps bispécifiques
CN104524568B (zh) * 2015-01-08 2018-04-20 中国人民解放军第二军医大学 一种治疗肥胖症的药物组合物及其应用
EP3328898B8 (fr) * 2015-07-28 2024-04-10 6452728 Canada Corp. Compositions d'agoniste trkb ou trkc et méthodes de traitement de troubles otiques
CA3005491A1 (fr) 2015-11-17 2017-05-26 Glaxosmithkline Intellectual Property Development Limited Agonistes de liaison utilises pour le traitement de troubles neurologiques et d'autres troubles
US9914781B1 (en) 2016-11-08 2018-03-13 Glaxosmithkline Intellectual Property Development Limited Binding agonist for treatment of neurological and other disorders
US11866506B2 (en) 2017-04-21 2024-01-09 Mellitus, Llc Anti-CD59 antibodies
US10793634B2 (en) * 2017-06-09 2020-10-06 Boehringer Ingelheim International Gmbh Anti-TrkB antibodies
PH12020550409A1 (en) 2017-11-30 2021-04-12 Regeneron Pharma Anti-trkb monoclonal antibodies and methods of use
WO2019165421A1 (fr) * 2018-02-26 2019-08-29 Minerva Biotechnologies Corporation Procédés de diagnostic utilisant des anticorps anti-muc1*
CN110818797B (zh) * 2018-08-09 2022-11-04 东莞市朋志生物科技有限公司 一种抗人ca153蛋白的重组抗体
JP7633397B2 (ja) 2020-10-21 2025-02-19 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 眼の疾患の処置のための二重特異性抗ＶＥＧＦ及び抗ＴｒｋＢ結合分子
WO2023125485A1 (fr) * 2021-12-28 2023-07-06 4B Technologies (Beijing) Co., Limited Anticorps trkb et son application

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4308689A (en) 1988-09-02 1990-04-02 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
WO1991010737A1 (fr) 1990-01-11 1991-07-25 Molecular Affinities Corporation Production d'anticorps utilisant des librairies de genes
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
EP1471142B1 (fr) 1991-04-10 2008-11-19 The Scripps Research Institute Banques de récepteurs hétérodimères utilisant des phagémides
PT1024191E (pt) 1991-12-02 2008-12-22 Medical Res Council Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
JPH09506262A (ja) 1993-12-08 1997-06-24 ジェンザイム・コーポレイション 特異的抗体の製造方法
ES2201097T3 (es) 1994-01-31 2004-03-16 Trustees Of Boston University Bibliotecas de anticuerpos policlonales.
US5601820A (en) * 1994-07-07 1997-02-11 Children's Hospital Of Philadelphia Compositions and methods of making and using human full length TRK-B
WO2006133164A2 (fr) * 2005-06-06 2006-12-14 Wyeth Anticorps monoclonaux anti-trkb et utilisations de ceux-ci
WO2007088479A1 (fr) * 2006-02-02 2007-08-09 Rinat Neuroscience Corp. Procédés de traitement de l'obésité par administration d'un antagoniste trkb
KR20080091838A (ko) * 2006-02-02 2008-10-14 리나트 뉴로사이언스 코퍼레이션 Ｔｒｋｂ 작용제의 투여에 의한 원치않는 체중 감소 또는 섭식 장애의 치료 방법

Also Published As

Publication number Publication date
IL198468A0 (en) 2011-08-01
AR063640A1 (es) 2009-02-04
NI200900081U (es) 2010-03-16
US20100150914A1 (en) 2010-06-17
MX2009004881A (es) 2009-05-21
WO2008058127A3 (fr) 2008-10-02
TW200829270A (en) 2008-07-16
CO6180432A2 (es) 2010-07-19
AU2007316418A1 (en) 2008-05-15
ZA200902943B (en) 2010-05-26
MA30922B1 (fr) 2009-11-02
CN101573381A (zh) 2009-11-04
RU2009121641A (ru) 2010-12-20
CR10779A (es) 2009-07-03
ECSP099392A (es) 2009-07-31
CL2007003236A1 (es) 2008-06-13
NO20092217L (no) 2009-06-09
WO2008058127A2 (fr) 2008-05-15
EA200970469A1 (ru) 2010-04-30
BRPI0719000A2 (pt) 2013-12-10
JP2010509354A (ja) 2010-03-25
WO2008058127A9 (fr) 2008-08-21
DOP2009000102A (es) 2010-10-31
SMAP200900040A (it) 2010-01-19
PE20081168A1 (es) 2008-09-22
CA2669205A1 (fr) 2008-05-15
EP2087007A2 (fr) 2009-08-12
KR20090088896A (ko) 2009-08-20

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