+

SK9372000A3 - Substituted beta-alanines - Google Patents

Substituted beta-alanines Download PDF

Info

Publication number
SK9372000A3
SK9372000A3 SK937-2000A SK9372000A SK9372000A3 SK 9372000 A3 SK9372000 A3 SK 9372000A3 SK 9372000 A SK9372000 A SK 9372000A SK 9372000 A3 SK9372000 A3 SK 9372000A3
Authority
SK
Slovakia
Prior art keywords
compound
group
alkyl
acetyl
amino
Prior art date
Application number
SK937-2000A
Other languages
English (en)
Slovak (sk)
Inventor
Peter Charles Astles
Neil Victor Harris
Andrew David Morley
Original Assignee
Rhone Poulenc Rorer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9727532.5A external-priority patent/GB9727532D0/en
Application filed by Rhone Poulenc Rorer Ltd filed Critical Rhone Poulenc Rorer Ltd
Publication of SK9372000A3 publication Critical patent/SK9372000A3/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2632-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/272-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/42Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Polyamides (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
SK937-2000A 1997-12-23 1998-12-23 Substituted beta-alanines SK9372000A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9727532.5A GB9727532D0 (en) 1997-12-23 1997-12-23 Chemical compounds
US9260298P 1998-07-13 1998-07-13
PCT/GB1998/003859 WO1999033789A1 (fr) 1997-12-23 1998-12-23 β-ALANINES SUBSTITUEES

Publications (1)

Publication Number Publication Date
SK9372000A3 true SK9372000A3 (en) 2002-03-05

Family

ID=26312873

Family Applications (1)

Application Number Title Priority Date Filing Date
SK937-2000A SK9372000A3 (en) 1997-12-23 1998-12-23 Substituted beta-alanines

Country Status (19)

Country Link
EP (1) EP1042279B1 (fr)
JP (1) JP4555469B2 (fr)
KR (1) KR20010033520A (fr)
CN (1) CN1163477C (fr)
AT (1) ATE289991T1 (fr)
AU (1) AU747907B2 (fr)
BR (1) BR9814376A (fr)
CA (1) CA2316235A1 (fr)
CZ (1) CZ20002342A3 (fr)
DE (1) DE69829215T2 (fr)
ES (1) ES2235383T3 (fr)
HK (1) HK1034508A1 (fr)
HU (1) HUP0101701A3 (fr)
IL (1) IL136584A (fr)
NO (1) NO20003273D0 (fr)
NZ (1) NZ505363A (fr)
SK (1) SK9372000A3 (fr)
TR (1) TR200001947T2 (fr)
WO (1) WO1999033789A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0100336A3 (en) * 1998-01-23 2002-11-28 Novartis Ag Vla-4 antagonists, pharmaceutical compositions comprising them and process for preparing them
DE69937603T2 (de) * 1998-12-23 2008-10-23 Aventis Pharma Ltd., West Malling Dihydro-benzo(1,4)oxazine und tetrahydro-quinoxaline
CZ20012980A3 (cs) * 1999-02-18 2002-04-17 F. Hoffmann-La Roche Ag Thioamidové deriváty
IL149758A0 (en) 1999-12-28 2002-11-10 Pfizer Prod Inc Non-peptidyl inhibitors of vla-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases
DE10019755A1 (de) * 2000-04-20 2001-11-08 Bayer Ag Neue Aminoaryl/cycloalkylcarbonsäuren als Integrinantagonisten
FR2812633A1 (fr) * 2000-08-04 2002-02-08 Aventis Cropscience Sa Derives de phenyl(thio)urees et phenyl(thio)carbamates fongicides
GB2369357A (en) * 2000-10-09 2002-05-29 Bayer Ag Aliphatic, cyclic amino carboxylic acids as integrin antagonists
GB2367816A (en) 2000-10-09 2002-04-17 Bayer Ag Urea- and thiourea-containing derivatives of beta-amino acids
MXPA03003829A (es) * 2000-11-04 2003-07-28 Aventis Pharma Ltd Acidos alcanoicos substituidos.
RU2290403C2 (ru) 2000-12-28 2006-12-27 Дайити Фармасьютикал Ко., Лтд. Ингибиторы vla-4
GB2377933A (en) 2001-07-06 2003-01-29 Bayer Ag Succinic acid derivatives useful as integrin antagonists
TWI340134B (en) 2003-07-24 2011-04-11 Daiichi Seiyaku Co Cyclohexanecarboxylic acids
WO2006116399A2 (fr) * 2005-04-28 2006-11-02 Ferring B.V. Utilisation de nouveaux composes dans le traitement des maladies inflammatoires intestinales
WO2007069635A1 (fr) 2005-12-13 2007-06-21 Daiichi Sankyo Company, Limited Médicament inhibiteur de vla-4
EP2124996A4 (fr) 2007-02-20 2010-03-24 Merrimack Pharmaceuticals Inc Méthodes de traitement de la sclérose en plaques par administration d'une alpha-foetoprotéine combinée à un antagoniste de l'intégrine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6306840B1 (en) * 1995-01-23 2001-10-23 Biogen, Inc. Cell adhesion inhibitors
ES2161373T3 (es) * 1995-08-30 2001-12-01 Searle & Co Derivados de meta-guanidina, urea, tiourea o acido azaciclico-aminobenzoico como antagonistas de integrinas.
CA2250698A1 (fr) * 1996-03-29 1997-10-09 G.D. Searle & Co. Derives d'acide phenylpropanoique para-substitues, utilises comme antagonistes de l'integrine
AU2337097A (en) * 1996-03-29 1997-10-22 G.D. Searle & Co. Meta-substituted phenylene derivatives and their use as alphavbeta3 integrin antagonists or inhibitors
TR200001179T2 (tr) * 1997-10-31 2000-11-21 Aventis Pharma Ltd. Değiştirilmiş anilidler

Also Published As

Publication number Publication date
AU747907B2 (en) 2002-05-30
TR200001947T2 (tr) 2001-01-22
CN1283181A (zh) 2001-02-07
EP1042279A1 (fr) 2000-10-11
NZ505363A (en) 2005-02-25
AU1771999A (en) 1999-07-19
CN1163477C (zh) 2004-08-25
NO20003273L (no) 2000-06-22
WO1999033789A1 (fr) 1999-07-08
EP1042279B1 (fr) 2005-03-02
DE69829215D1 (de) 2005-04-07
ATE289991T1 (de) 2005-03-15
CZ20002342A3 (cs) 2001-11-14
IL136584A (en) 2005-03-20
BR9814376A (pt) 2000-10-10
DE69829215T2 (de) 2005-07-21
JP4555469B2 (ja) 2010-09-29
HUP0101701A2 (hu) 2001-11-28
IL136584A0 (en) 2001-06-14
NO20003273D0 (no) 2000-06-22
HK1034508A1 (en) 2001-10-26
HUP0101701A3 (en) 2003-02-28
KR20010033520A (ko) 2001-04-25
CA2316235A1 (fr) 1999-07-08
JP2001527061A (ja) 2001-12-25
ES2235383T3 (es) 2005-07-01

Similar Documents

Publication Publication Date Title
SK9372000A3 (en) Substituted beta-alanines
EP1114028B1 (fr) Bicycles aza modulant l'inhibition de l'adhesion cellulaire
EP1027328B1 (fr) Anilides substituees
EP1183254B1 (fr) Composes d'heteroaryle bicyclique substitue utilises comme antagonistes de l'integrine
EP1153017B1 (fr) Composes bicycliques et leur utilisation comme ligands du recepteur de l'integrine
JP2001523711A (ja) 細胞接着阻害薬としての環状アミノ酸誘導体
EP1392306B1 (fr) Tetrahydroisoquinolines substituees destinees au traitement des maladies inflammatoires
EP1177181B1 (fr) Composes bicycliques substitues
WO1999054321A1 (fr) Diamines substituees et leur utilisation en tant qu'inhibiteurs d'adhesion cellulaire
US6352977B1 (en) Substituted β-alanines
JP3786203B2 (ja) 置換アルカン酸
US6762199B2 (en) Indane derivatives
US6548533B2 (en) Ureido substituted pyrrolidines
ES2297943T3 (es) Dihidro-benzo(1,4)oxacinas y tetrahidroquinoxalinas.
MXPA00006218A (en) SUBSTITUTED&bgr;-ALANINES
JP4856314B2 (ja) 置換ピロリジン
点击 这是indexloc提供的php浏览器服务,不要输入任何密码和下载