SK7799A3 - Fusion polypeptides comprising an ige-binding domain and a hsa component, and their diagnostic and therapeutic uses - Google Patents

Fusion polypeptides comprising an ige-binding domain and a hsa component, and their diagnostic and therapeutic uses Download PDF

Info

Publication number: SK7799A3
Authority: SK; Slovakia
Prior art keywords: ige; hsa; polypeptide; leu; glu
Prior art date: 1996-07-26

Application number

SK77-99A

Other languages

English (en)

Slovak (sk)

Inventor

Mary E Digan

Philip Lake

Hermann Gram

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-26

Filing date

1997-07-25

Publication date

1999-07-12

1997-07-25 Application filed by Novartis Ag filed Critical Novartis Ag

1999-07-12 Publication of SK7799A3 publication Critical patent/SK7799A3/sk

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Toxicology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Cell Biology (AREA)
Physics & Mathematics (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pulmonology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

SK77-99A 1996-07-26 1997-07-25 Fusion polypeptides comprising an ige-binding domain and a hsa component, and their diagnostic and therapeutic uses SK7799A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US69021696A	1996-07-26	1996-07-26
PCT/EP1997/004066 WO1998004718A1 (fr)	1996-07-26	1997-07-25	Polypeptides de fusion comprenant un domaine de liaison ige et un composant hsa, et leurs utilisations diagnostiques et therapeutiques

Publications (1)

Publication Number	Publication Date
SK7799A3 true SK7799A3 (en)	1999-07-12

Family

ID=24771594

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK77-99A SK7799A3 (en)	1996-07-26	1997-07-25	Fusion polypeptides comprising an ige-binding domain and a hsa component, and their diagnostic and therapeutic uses

Country Status (28)

Country	Link
EP (1)	EP0917581B1 (fr)
JP (1)	JP3681402B2 (fr)
KR (1)	KR100502879B1 (fr)
CN (1)	CN1146664C (fr)
AR (1)	AR008077A1 (fr)
AT (1)	ATE383429T1 (fr)
AU (1)	AU722069B2 (fr)
BR (1)	BR9710605A (fr)
CA (1)	CA2261562C (fr)
CO (1)	CO4650184A1 (fr)
CZ (1)	CZ297634B6 (fr)
DE (1)	DE69738452T2 (fr)
ES (1)	ES2300114T3 (fr)
HK (1)	HK1020352A1 (fr)
ID (1)	ID19420A (fr)
IL (2)	IL128094A0 (fr)
MY (1)	MY120425A (fr)
NO (1)	NO323611B1 (fr)
NZ (1)	NZ333908A (fr)
PE (1)	PE99498A1 (fr)
PL (1)	PL189415B1 (fr)
PT (1)	PT917581E (fr)
RU (1)	RU2209211C2 (fr)
SK (1)	SK7799A3 (fr)
TR (1)	TR199900155T2 (fr)
TW (1)	TW565571B (fr)
WO (1)	WO1998004718A1 (fr)
ZA (1)	ZA976666B (fr)

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AU6755300A (en) *	1999-08-09	2001-03-05	Genaissance Pharmaceuticals, Inc.	Drug target isogenes: polymorphisms in the immunoglobulin e receptor i alpha subunit gene
US6946134B1 (en)	2000-04-12	2005-09-20	Human Genome Sciences, Inc.	Albumin fusion proteins
AU2001264563A1 (en)	2000-04-12	2001-10-30	Human Genome Sciences, Inc.	Albumin fusion proteins
DE10026998A1 (de) *	2000-05-31	2001-12-13	Fresenius Kabi De Gmbh	Verfahren zur Herstellung einer kosmetischen Zusammensetzung, die humanes Serum Albumin umfasst, welches aus transgenen nicht-menschlichen Säugern erhalten wurde
IL155812A0 (en)	2000-12-07	2003-12-23	Lilly Co Eli	Glp-1 fusion proteins
TWI329129B (en) *	2001-02-08	2010-08-21	Wyeth Corp	Modified and stabilized gdf propeptides and uses thereof
US7507413B2 (en)	2001-04-12	2009-03-24	Human Genome Sciences, Inc.	Albumin fusion proteins
PT1463751E (pt)	2001-12-21	2013-08-26	Human Genome Sciences Inc	Proteínas de fusão de albumina
WO2005003296A2 (fr)	2003-01-22	2005-01-13	Human Genome Sciences, Inc.	Proteines hybrides d'albumine
WO2010059315A1 (fr)	2008-11-18	2010-05-27	Merrimack Pharmaceuticals, Inc.	Lieurs de sérum-albumine humaine et conjugués de ceux-ci
CA2753813C (fr)	2009-02-27	2018-12-11	Novartis Ag	Procede de selection de cellules hotes eucaryotes exprimant une proteine heterologue
WO2012169735A2 (fr) *	2011-06-07	2012-12-13	(주)네오팜	Complexe comprenant des fragments hydrosolubles de fcεri et composition le contenant pour traiter les maladies allergiques médiées par l'ige
RU2506271C2 (ru) *	2011-06-22	2014-02-10	Учреждение Российской Академии Медицинских Наук Научно-исследовательский институт экспериментальной медицины Северо-западного отделения РАМН (НИИЭМ СЗО РАМН)	РЕКОМБИНАНТНЫЙ ПОЛИПЕПТИД А2, СЕЛЕКТИВНО СВЯЗЫВАЮЩИЙ HSA, РЕКОМБИНАНТНАЯ ДНК pa2, КОДИРУЮЩАЯ HSA-СВЯЗЫВАЮЩУЮ ЧАСТЬ ПОЛИПЕПТИДА A2, ЕГО ПРОДУЦЕНТ - РЕКОМБИНАНТНЫЙ ШТАММ Escherichia coli M15-A2, СОДЕРЖАЩИЙ РЕКОМБИНАНТНУЮ ПЛАЗМИДНУЮ ДНК pQE 32-pa2, ОБЕСПЕЧИВАЮЩУЮ ПОЛУЧЕНИЕ ПОЛИПЕПТИДА A2 И ПРИМЕНЕНИЕ ПОЛИПЕПТИДА А2 ДЛЯ ДИАГНОСТИКИ МИКРОАЛЬБУМИНУРИИ И ВЫДЕЛЕНИЯ HSA ИЗ СЫВОРОТКИ КРОВИ
WO2014036520A1 (fr)	2012-08-30	2014-03-06	Merrimack Pharmaceuticals, Inc.	Polythérapies comprenant des agents anti-erbb3
CN107979973A (zh) *	2015-05-04	2018-05-01	法国化学与生物科技实验室	Fc融合蛋白质的转基因生产
EP3192806A1 (fr)	2016-01-13	2017-07-19	Affiris AG	Chaîne alpha du récepteur de l'ige haute affinité (fceria)
WO2018089335A1 (fr)	2016-11-09	2018-05-17	North Carolina State University	Traitement de maladies allergiques au moyen d'une protéine chimérique
WO2019183437A1 (fr)	2018-03-23	2019-09-26	North Carolina State University	Procédés et compositions pour un anticorps dirigé contre un récepteur ige de haute affinité
PH12022550043A1 (en)	2019-07-08	2023-02-27	Gi Innovation Inc	Polypeptide dimer with high sialic acid content, comprising extracellular domain of alpha subunit of ige fc receptor, and pharmaceutical composition comprising same
KR20210006302A (ko) *	2019-07-08	2021-01-18	주식회사 프로젠	신규 il-10 변이체 단백질 및 그의 용도
CN111773392B (zh) *	2020-05-25	2023-04-07	河南省生物工程技术研究中心	一种人血白蛋白/寡核苷酸纳米颗粒及其制备方法和用途

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US4962035A (en) *	1987-12-01	1990-10-09	President And Fellows Of Harvard College	DNA encoding IgE receptor alpha-subunit or fragment thereof
GB8909916D0 (en) *	1989-04-29	1989-06-14	Delta Biotechnology Ltd	Polypeptides
CA2059842A1 (fr) *	1991-02-11	1992-08-12	Richard A. Chizzonite	Anticorps recepteurs d'ige

1997
- 1997-07-24 AR ARP970103340A patent/AR008077A1/es active IP Right Grant
- 1997-07-24 MY MYPI97003371A patent/MY120425A/en unknown
- 1997-07-24 PE PE1997000662A patent/PE99498A1/es not_active Application Discontinuation
- 1997-07-25 KR KR10-1999-7000621A patent/KR100502879B1/ko not_active Expired - Fee Related
- 1997-07-25 EP EP97940030A patent/EP0917581B1/fr not_active Expired - Lifetime
- 1997-07-25 TR TR1999/00155T patent/TR199900155T2/xx unknown
- 1997-07-25 RU RU99103326/13A patent/RU2209211C2/ru not_active IP Right Cessation
- 1997-07-25 ID IDP972592A patent/ID19420A/id unknown
- 1997-07-25 PT PT97940030T patent/PT917581E/pt unknown
- 1997-07-25 SK SK77-99A patent/SK7799A3/sk unknown
- 1997-07-25 CZ CZ0024699A patent/CZ297634B6/cs not_active IP Right Cessation
- 1997-07-25 WO PCT/EP1997/004066 patent/WO1998004718A1/fr active IP Right Grant
- 1997-07-25 DE DE69738452T patent/DE69738452T2/de not_active Expired - Lifetime
- 1997-07-25 BR BR9710605A patent/BR9710605A/pt not_active IP Right Cessation
- 1997-07-25 AT AT97940030T patent/ATE383429T1/de active
- 1997-07-25 ZA ZA976666A patent/ZA976666B/xx unknown
- 1997-07-25 CO CO97042651A patent/CO4650184A1/es unknown
- 1997-07-25 ES ES97940030T patent/ES2300114T3/es not_active Expired - Lifetime
- 1997-07-25 AU AU42025/97A patent/AU722069B2/en not_active Ceased
- 1997-07-25 IL IL12809497A patent/IL128094A0/xx active IP Right Grant
- 1997-07-25 CN CNB971976597A patent/CN1146664C/zh not_active Expired - Fee Related
- 1997-07-25 CA CA2261562A patent/CA2261562C/fr not_active Expired - Fee Related
- 1997-07-25 NZ NZ333908A patent/NZ333908A/en unknown
- 1997-07-25 JP JP50850498A patent/JP3681402B2/ja not_active Expired - Fee Related
- 1997-08-08 TW TW086111356A patent/TW565571B/zh not_active IP Right Cessation
1999
- 1999-01-18 IL IL128094A patent/IL128094A/en not_active IP Right Cessation
- 1999-01-25 PL PL97331356A patent/PL189415B1/pl not_active IP Right Cessation
- 1999-01-25 NO NO19990328A patent/NO323611B1/no not_active IP Right Cessation
- 1999-11-24 HK HK99105437A patent/HK1020352A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO990328L (no)	1999-02-19
CO4650184A1 (es)	1998-09-03
PL331356A1 (en)	1999-07-05
EP0917581B1 (fr)	2008-01-09
CZ297634B6 (cs)	2007-02-21
ID19420A (id)	1998-07-09
AU4202597A (en)	1998-02-20
TW565571B (en)	2003-12-11
DE69738452D1 (de)	2008-02-21
KR20000029563A (ko)	2000-05-25
KR100502879B1 (ko)	2005-07-25
CA2261562A1 (fr)	1998-02-05
PT917581E (pt)	2008-04-11
HK1020352A1 (en)	2000-04-14
PL189415B1 (pl)	2005-08-31
MY120425A (en)	2005-10-31
CZ24699A3 (cs)	1999-04-14
ZA976666B (en)	1999-01-25
ES2300114T3 (es)	2008-06-01
CN1146664C (zh)	2004-04-21
PE99498A1 (es)	1999-01-21
JP3681402B2 (ja)	2005-08-10
BR9710605A (pt)	1999-08-17
IL128094A0 (en)	1999-11-30
AR008077A1 (es)	1999-12-09
EP0917581A1 (fr)	1999-05-26
NZ333908A (en)	1999-10-28
TR199900155T2 (xx)	2000-08-21
WO1998004718A1 (fr)	1998-02-05
RU2209211C2 (ru)	2003-07-27
IL128094A (en)	2006-08-20
AU722069B2 (en)	2000-07-20
CN1229439A (zh)	1999-09-22
NO323611B1 (no)	2007-06-18
ATE383429T1 (de)	2008-01-15
CA2261562C (fr)	2011-04-05
JP2000516089A (ja)	2000-12-05
DE69738452T2 (de)	2008-12-24
NO990328D0 (no)	1999-01-25

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JP2008506635A (ja)	2008-03-06	Ｆｇｆ−２１融合タンパク質
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