SK1498A3 - Layered tablet for the controlled release of active substances - Google Patents

Layered tablet for the controlled release of active substances Download PDF

Info

Publication number: SK1498A3
Authority: SK; Slovakia
Prior art keywords: matrix; layer; layered; layered tablet; thickness
Prior art date: 1995-07-07

Application number

SK14-98A

Other languages

English (en)

Slovak (sk)

Inventor

Karsten Cremer

Original Assignee

Lohmann Therapie Syst Lts

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-07

Filing date

1996-06-24

Publication date

1998-09-09

1996-06-24 Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts

1998-09-09 Publication of SK1498A3 publication Critical patent/SK1498A3/sk

Links

239000007942 layered tablet Substances 0.000 title claims abstract description 46
239000013543 active substance Substances 0.000 title claims abstract description 45
238000013270 controlled release Methods 0.000 title claims abstract description 8
239000011159 matrix material Substances 0.000 claims abstract description 56
239000007788 liquid Substances 0.000 claims abstract description 17
239000008187 granular material Substances 0.000 claims abstract description 8
238000003825 pressing Methods 0.000 claims abstract description 7
239000012254 powdered material Substances 0.000 claims abstract 3
238000000576 coating method Methods 0.000 claims description 27
239000003826 tablet Substances 0.000 claims description 24
239000011248 coating agent Substances 0.000 claims description 23
239000004480 active ingredient Substances 0.000 claims description 19
239000000463 material Substances 0.000 claims description 15
239000000843 powder Substances 0.000 claims description 8
230000003628 erosive effect Effects 0.000 claims description 7
239000003814 drug Substances 0.000 claims description 5
230000000295 complement effect Effects 0.000 claims description 3
229920006254 polymer film Polymers 0.000 claims description 2
230000013011 mating Effects 0.000 claims 2
239000000758 substrate Substances 0.000 claims 2
238000001125 extrusion Methods 0.000 claims 1
230000002496 gastric effect Effects 0.000 claims 1
230000002401 inhibitory effect Effects 0.000 claims 1
239000008194 pharmaceutical composition Substances 0.000 claims 1
238000002360 preparation method Methods 0.000 claims 1
230000001934 delay Effects 0.000 abstract 1
239000010410 layer Substances 0.000 description 52
239000002609 medium Substances 0.000 description 15
238000004519 manufacturing process Methods 0.000 description 8
230000006835 compression Effects 0.000 description 6
238000007906 compression Methods 0.000 description 6
230000000694 effects Effects 0.000 description 6
238000009792 diffusion process Methods 0.000 description 5
238000000034 method Methods 0.000 description 5
238000000465 moulding Methods 0.000 description 5
229940079593 drug Drugs 0.000 description 4
210000001035 gastrointestinal tract Anatomy 0.000 description 4
239000012736 aqueous medium Substances 0.000 description 2
239000002775 capsule Substances 0.000 description 2
239000011247 coating layer Substances 0.000 description 2
239000012530 fluid Substances 0.000 description 2
238000012423 maintenance Methods 0.000 description 2
239000000203 mixture Substances 0.000 description 2
238000004806 packaging method and process Methods 0.000 description 2
239000002245 particle Substances 0.000 description 2
230000002093 peripheral effect Effects 0.000 description 2
239000000546 pharmaceutical excipient Substances 0.000 description 2
230000002035 prolonged effect Effects 0.000 description 2
230000008961 swelling Effects 0.000 description 2
238000012546 transfer Methods 0.000 description 2
230000002378 acidificating effect Effects 0.000 description 1
239000002318 adhesion promoter Substances 0.000 description 1
230000004888 barrier function Effects 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
230000001447 compensatory effect Effects 0.000 description 1
238000010276 construction Methods 0.000 description 1
230000007423 decrease Effects 0.000 description 1
230000003111 delayed effect Effects 0.000 description 1
239000002552 dosage form Substances 0.000 description 1
239000008298 dragée Substances 0.000 description 1
238000003255 drug test Methods 0.000 description 1
238000005516 engineering process Methods 0.000 description 1
239000007888 film coating Substances 0.000 description 1
238000009501 film coating Methods 0.000 description 1
210000004051 gastric juice Anatomy 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
230000000977 initiatory effect Effects 0.000 description 1
238000012545 processing Methods 0.000 description 1
230000000979 retarding effect Effects 0.000 description 1
230000002441 reversible effect Effects 0.000 description 1
239000007787 solid Substances 0.000 description 1
210000002784 stomach Anatomy 0.000 description 1
239000000126 substance Substances 0.000 description 1
239000013589 supplement Substances 0.000 description 1
230000002522 swelling effect Effects 0.000 description 1
238000012360 testing method Methods 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
238000002560 therapeutic procedure Methods 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Preparation (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Electrotherapy Devices (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Financial Or Insurance-Related Operations Such As Payment And Settlement (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

SK14-98A 1995-07-07 1996-06-24 Layered tablet for the controlled release of active substances SK1498A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19524753A DE19524753A1 (de)	1995-07-07	1995-07-07	Schichttablette zur kontrollierten Freisetzung von Wirkstoffen
PCT/EP1996/002736 WO1997002812A2 (fr)	1995-07-07	1996-06-24	Comprime stratifie pour la liberation controlee de substances actives

Publications (1)

Publication Number	Publication Date
SK1498A3 true SK1498A3 (en)	1998-09-09

Family

ID=7766243

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK14-98A SK1498A3 (en)	1995-07-07	1996-06-24	Layered tablet for the controlled release of active substances

Country Status (20)

Country	Link
US (1)	US6083533A (fr)
EP (1)	EP0837674B1 (fr)
JP (1)	JPH11510484A (fr)
KR (1)	KR100404121B1 (fr)
CN (1)	CN1190343A (fr)
AT (1)	ATE210972T1 (fr)
AU (1)	AU710828B2 (fr)
CZ (1)	CZ420997A3 (fr)
DE (2)	DE19524753A1 (fr)
DK (1)	DK0837674T3 (fr)
ES (1)	ES2170245T3 (fr)
HU (1)	HUP9901715A3 (fr)
MY (1)	MY113919A (fr)
NO (1)	NO976140L (fr)
NZ (1)	NZ312136A (fr)
PL (1)	PL324487A1 (fr)
PT (1)	PT837674E (fr)
SK (1)	SK1498A3 (fr)
WO (1)	WO1997002812A2 (fr)
ZA (1)	ZA965710B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6555139B2 (en)	1999-06-28	2003-04-29	Wockhardt Europe Limited	Preparation of micron-size pharmaceutical particles by microfluidization
USD481456S1 (en)	2002-01-30	2003-10-28	Smithkline Beecham P.L.C.	Capsule
HRP20020124A2 (en) *	2002-02-11	2003-10-31	Pliva D D	Sustained/controlled release solid formulation as a novel drug delivery system with reduced risk of dose dumping
US7309444B2 (en) *	2002-08-29	2007-12-18	Stellar Technology Company	Layered tablet water treatment compositions and method of use
US6852238B2 (en) *	2002-08-29	2005-02-08	Steller Technology Company	Layered tablet water treatment compositions and method of use
US20060251722A1 (en) *	2005-05-03	2006-11-09	Novavax, Inc.	Multi-component vitamin and mineral supplement for the optimal absorption of components
US20080286343A1 (en) *	2007-05-16	2008-11-20	Dzenana Cengic	Solid form
US8609330B2 (en)	2008-12-31	2013-12-17	3M Innovative Properties Company	Live Bioload detection using microparticles
BRPI0918693A2 (pt)	2008-12-31	2016-07-26	3M Innovative Properties Co	dispositivos para amostragem e métodos para concentração de microorganismos
WO2010129726A1 (fr) *	2009-05-06	2010-11-11	3M Innovative Properties Company	Articles à matrice comprenant un agent d'extraction cellulaire et procédés de biodétection associés
JP5972174B2 (ja)	2009-12-30	2016-08-17	スリーエムイノベイティブプロパティズカンパニー	微小粒子を用いた生きた生物負荷の検出法
WO2011082258A2 (fr)	2009-12-30	2011-07-07	Regents Of The University Of Minnesota	Ciment osseux et procédé correspondant
CN110538158A (zh) *	2019-09-10	2019-12-06	郑州百瑞动物药业有限公司	一种水产用长效缓释双层片状消毒剂及其制备方法
CN113768038A (zh) *	2021-09-14	2021-12-10	江苏省协同医药生物工程有限责任公司	一种精准定量实验动物功能性饲料及制备方法与设备

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US1248571A (en) *	1917-04-30	1917-12-04	Francis J Stokes	Machine for applying and compressing powder on tablets.
DE3221425A1 (de) *	1982-06-07	1983-12-08	Boehringer Ingelheim KG, 6507 Ingelheim	Hydrolyseempfindlichen wirkstoff enthaltende, lagerstabile tablette
DE3814532A1 (de) *	1988-04-29	1989-11-09	Bayer Ag	Dhp-retard-zubereitung
DE4100920A1 (de) *	1991-01-15	1992-07-16	Degussa	Wirkstoffzubereitung zur oralen verabreichung an wiederkaeuer
IT1256393B (it) *	1992-11-17	1995-12-04	Inverni Della Beffa Spa	Forme matriciali multistrato per il rilascio controllato di principi attivi
DE4341442C2 (de) *	1993-12-04	1998-11-05	Lohmann Therapie Syst Lts	Vorrichtung zur kontrollierten Freisetzung von Wirkstoffen sowie ihre Verwendung
DE4416926C2 (de) *	1994-05-13	2000-01-13	Lohmann Therapie Syst Lts	Verfahren zur Herstellung von Vorrichtungen zur kontrollierten Freisetzung von Wirkstoffen

1995
- 1995-07-07 DE DE19524753A patent/DE19524753A1/de not_active Withdrawn
1996
- 1996-06-24 HU HU9901715A patent/HUP9901715A3/hu unknown
- 1996-06-24 KR KR10-1998-0700083A patent/KR100404121B1/ko not_active Expired - Fee Related
- 1996-06-24 PL PL96324487A patent/PL324487A1/xx unknown
- 1996-06-24 AT AT96922890T patent/ATE210972T1/de not_active IP Right Cessation
- 1996-06-24 NZ NZ312136A patent/NZ312136A/xx unknown
- 1996-06-24 EP EP96922890A patent/EP0837674B1/fr not_active Expired - Lifetime
- 1996-06-24 AU AU63598/96A patent/AU710828B2/en not_active Ceased
- 1996-06-24 CN CN96195323A patent/CN1190343A/zh active Pending
- 1996-06-24 PT PT96922890T patent/PT837674E/pt unknown
- 1996-06-24 US US08/983,278 patent/US6083533A/en not_active Expired - Fee Related
- 1996-06-24 JP JP9505453A patent/JPH11510484A/ja active Pending
- 1996-06-24 CZ CZ974209A patent/CZ420997A3/cs unknown
- 1996-06-24 DK DK96922890T patent/DK0837674T3/da active
- 1996-06-24 WO PCT/EP1996/002736 patent/WO1997002812A2/fr active IP Right Grant
- 1996-06-24 ES ES96922890T patent/ES2170245T3/es not_active Expired - Lifetime
- 1996-06-24 DE DE59608511T patent/DE59608511D1/de not_active Expired - Fee Related
- 1996-06-24 SK SK14-98A patent/SK1498A3/sk unknown
- 1996-06-28 MY MYPI96002655A patent/MY113919A/en unknown
- 1996-07-05 ZA ZA965710A patent/ZA965710B/xx unknown
1997
- 1997-12-30 NO NO976140A patent/NO976140L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
ZA965710B (en)	1997-01-24
NZ312136A (en)	1999-02-25
WO1997002812A2 (fr)	1997-01-30
JPH11510484A (ja)	1999-09-14
AU6359896A (en)	1997-02-10
EP0837674A2 (fr)	1998-04-29
US6083533A (en)	2000-07-04
MX9800244A (es)	1998-07-31
CZ420997A3 (cs)	1998-06-17
MY113919A (en)	2002-06-29
DE19524753A1 (de)	1997-01-23
HUP9901715A3 (en)	2001-04-28
ES2170245T3 (es)	2002-08-01
PT837674E (pt)	2002-06-28
NO976140D0 (no)	1997-12-30
KR100404121B1 (ko)	2004-02-11
PL324487A1 (en)	1998-05-25
CN1190343A (zh)	1998-08-12
ATE210972T1 (de)	2002-01-15
WO1997002812A3 (fr)	1997-03-27
DE59608511D1 (de)	2002-01-31
NO976140L (no)	1997-12-30
HUP9901715A2 (hu)	1999-10-28
KR19990028783A (ko)	1999-04-15
DK0837674T3 (da)	2002-04-08
EP0837674B1 (fr)	2001-12-19
AU710828B2 (en)	1999-09-30

Publication	Publication Date	Title
SK1498A3 (en)	1998-09-09	Layered tablet for the controlled release of active substances
US6702683B2 (en)	2004-03-09	Metering and packaging of controlled release medication
CA2294744C (fr)	2006-10-17	Forme galenique effervescente constituee d'unites multiples
JP2024097068A (ja)	2024-07-17	特定の胃腸部位での制御放出の剤形
EP1416920B1 (fr)	2007-01-10	Systeme multiplexe de liberation de medicaments approprie a l'administration par voie orale
CZ189597A3 (cs)	1998-02-18	Dávkovací prostředek pro řízené uvolňování suspenze léčiva
JP2019520866A (ja)	2019-07-25	放出制御剤形
EP0542364A1 (fr)	1993-05-19	Dispositif à libération contrôlée
CA2348090A1 (fr)	2000-04-27	Systeme d'administration de medicaments par doses pulsees par voie orale
SK27099A3 (en)	1999-12-10	Tablet with controlled release of alfuzosine chlorhydrate
CN116018131A (zh)	2023-04-25	具有内腔的快速口腔分散片剂
DE3715224A1 (de)	1987-11-12	Dosierungsform zur stossweisen freisetzung eines arzneimittels
SK30396A3 (en)	1997-09-10	Beads, method for producing them and a pharmaceutical preparation containing the same
HUP0204122A2 (hu)	2003-03-28	Dioxo-tiazolidint és hetformint tartalmazó gyógyszerkészítmény és felhasználása
SK279964B6 (sk)	1999-06-11	Dávkovacia forma na riadené uvoľňovanie liečiva a
SK284552B6 (sk)	2005-06-02	Trojvrstvová tableta s riadeným uvoľňovaním účinnej zložky na orálne podávanie
JP2021001190A (ja)	2021-01-07	トリパルス放出型賦活薬製剤
KR102718549B1 (ko)	2024-10-17	약물 전달 시스템을 제조하기 위한 방법
CA2226147C (fr)	2005-11-15	Comprime stratifie pour la liberation controlee de substances actives
Panda et al.	2021	Bi-Layer Tablets: An Emerging State of Art Technology in Dosage Form Design
MXPA98000244A (en)	1998-11-09	Tablet in layers for the controlled release of acti prints
CA2206211C (fr)	2006-08-08	Dispositif de liberation controlee d'une suspension medicamenteuse
Thirupathaiah et al.	2016	TRILAYER SUSTAINED RELEASE DRUGS OF ANTILIPIDEMIC DRUGS BY GEOMATRIX TECHNOLOGY–REVIEW.