SI0876393T1 - 21-(2-oxo-tetrahydrofuran)-thio pregnane derivatives, a process for their production and pharmaceutical compositions containing them - Google Patents
21-(2-oxo-tetrahydrofuran)-thio pregnane derivatives, a process for their production and pharmaceutical compositions containing themInfo
- Publication number
- SI0876393T1 SI0876393T1 SI9630233T SI9630233T SI0876393T1 SI 0876393 T1 SI0876393 T1 SI 0876393T1 SI 9630233 T SI9630233 T SI 9630233T SI 9630233 T SI9630233 T SI 9630233T SI 0876393 T1 SI0876393 T1 SI 0876393T1
- Authority
- SI
- Slovenia
- Prior art keywords
- pct
- thio
- oxo
- tetrahydrofuran
- production
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 239000012453 solvate Substances 0.000 abstract 2
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000000043 antiallergic agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 150000003128 pregnanes Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9526630.0A GB9526630D0 (en) | 1995-12-29 | 1995-12-29 | Compounds |
| GBGB9613036.4A GB9613036D0 (en) | 1996-06-21 | 1996-06-21 | Compounds |
| EP96943204A EP0876393B1 (fr) | 1995-12-29 | 1996-12-19 | Derives de 21-(2-oxo-tetrahydrofurane)-thiopregnane, leur procede de preparation et compositions pharmaceutiques les contenant |
| PCT/GB1996/003153 WO1997024367A1 (fr) | 1995-12-29 | 1996-12-19 | Derives de 21-(2-oxo-tetrahydrofurane)-thiopregnane, leur procede de preparation et compositions pharmaceutiques les contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI0876393T1 true SI0876393T1 (en) | 2000-12-31 |
Family
ID=26308399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9630233T SI0876393T1 (en) | 1995-12-29 | 1996-12-19 | 21-(2-oxo-tetrahydrofuran)-thio pregnane derivatives, a process for their production and pharmaceutical compositions containing them |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6013244A (fr) |
| EP (1) | EP0876393B1 (fr) |
| JP (1) | JP2947945B2 (fr) |
| AT (1) | ATE194357T1 (fr) |
| AU (1) | AU1200097A (fr) |
| DE (1) | DE69609201T2 (fr) |
| DK (1) | DK0876393T3 (fr) |
| ES (1) | ES2150151T3 (fr) |
| GR (1) | GR3034563T3 (fr) |
| PT (1) | PT876393E (fr) |
| SI (1) | SI0876393T1 (fr) |
| WO (1) | WO1997024367A1 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2215310T3 (es) * | 1997-06-30 | 2004-10-01 | Glaxo Group Limited | Procedimiento para identificar compuestos que tienen una actividad sistemica reducida. |
| WO2004028545A1 (fr) * | 2002-09-25 | 2004-04-08 | Astrazeneca Ab | Combinaison d'un agoniste $g(b)2 a action prolongee et d'un glucocorticosteroide dans le traitement de maladies fibrotiques |
| WO2008124145A1 (fr) * | 2007-04-05 | 2008-10-16 | Government Of The U.S.A., As Represented By The Secretary, Department Of Health And Human Services | Composés stéroïdes, compositions et procédés de traitement |
| MX2010007024A (es) * | 2007-12-21 | 2010-09-30 | Schering Corp | Tioéteres c-21 como agonista del receptor de glucocorticoides. |
| WO2010147947A2 (fr) | 2009-06-16 | 2010-12-23 | Schering Corporation | Nouveaux [3,2-c] hétéroaryl stéroïdes en tant qu'agonistes des récepteurs glucocorticoïdes, compositions et utilisations de ceux-ci |
| WO2024125639A1 (fr) * | 2022-12-16 | 2024-06-20 | 津药生物科技（天津）有限公司 | Nouveau glucocorticoïde, son procédé de préparation et son utilisation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5420120A (en) * | 1993-12-17 | 1995-05-30 | Alcon Laboratories, Inc. | Anti-inflammatory glucocorticoid compounds for topical ophthalmic use |
-
1996
- 1996-12-19 WO PCT/GB1996/003153 patent/WO1997024367A1/fr active IP Right Grant
- 1996-12-19 EP EP96943204A patent/EP0876393B1/fr not_active Expired - Lifetime
- 1996-12-19 DE DE69609201T patent/DE69609201T2/de not_active Expired - Fee Related
- 1996-12-19 SI SI9630233T patent/SI0876393T1/xx unknown
- 1996-12-19 JP JP9524096A patent/JP2947945B2/ja not_active Expired - Fee Related
- 1996-12-19 AT AT96943204T patent/ATE194357T1/de not_active IP Right Cessation
- 1996-12-19 AU AU12000/97A patent/AU1200097A/en not_active Abandoned
- 1996-12-19 DK DK96943204T patent/DK0876393T3/da active
- 1996-12-19 PT PT96943204T patent/PT876393E/pt unknown
- 1996-12-19 US US09/091,749 patent/US6013244A/en not_active Expired - Fee Related
- 1996-12-19 ES ES96943204T patent/ES2150151T3/es not_active Expired - Lifetime
-
2000
- 2000-10-04 GR GR20000402253T patent/GR3034563T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997024367A1 (fr) | 1997-07-10 |
| PT876393E (pt) | 2000-12-29 |
| DK0876393T3 (da) | 2000-11-06 |
| ATE194357T1 (de) | 2000-07-15 |
| EP0876393B1 (fr) | 2000-07-05 |
| GR3034563T3 (en) | 2001-01-31 |
| JPH11501676A (ja) | 1999-02-09 |
| EP0876393A1 (fr) | 1998-11-11 |
| JP2947945B2 (ja) | 1999-09-13 |
| US6013244A (en) | 2000-01-11 |
| DE69609201T2 (de) | 2001-03-01 |
| ES2150151T3 (es) | 2000-11-16 |
| AU1200097A (en) | 1997-07-28 |
| DE69609201D1 (de) | 2000-08-10 |
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