RU2371364C1 - Container with internal mixing and liberated internal vessel and method of its filling - Google Patents

Abstract

FIELD: transportation, packing and storage.

SUBSTANCE: invention relates to container with internal mixing and liberated internal vessel in wherein it is possible to mix up at least two types of substances. Proposed container consists of container casing, external head and internal vessel. In container casing and internal vessel, materials of different types are kept independently, while previously mentioned head has inner and outer walls. Internal vessel is densely pressed, end-to-end, threaded or bayonet-jointed to external head to make internal vessel-external head assembly. External wall of internal vessel is furnished with ratchet, while internal wall of container casing neck is provided with cams mating the position of aforesaid ratchet. Above specified positions of ratchet and cams are selected to prevent rotation of internal vessel together with external head. The internal vessel is separated from external head in rotating external head for internal vessel to fall in container casing by gravity.

EFFECT: simple design, longer life and lower costs.

21 cl, 13 dwg

Description

Technical field

The present invention relates to an internal mixing container and a releasable inner vessel in which at least two types of contents can be mixed with each other, mainly liquid with liquid, liquid with a solid component or solid component with a solid component, and also specified container. In other words, at least two types of materials are packaged in the same container, in which it is possible to quickly mix and compose a composition of these two types of materials without damaging the container body during use.

State of the art

Packaging products in a container or vessel is a common packaging technology. However, in one conventional container, only one type of material may be contained. Separate packaging is required for packaging several types of materials. If the materials are used as a mixture, they can only be mixed outside the containers in which they are packaged. In this regard, at least two containers are necessary; this leads to the inconvenience of using many products that need to be mixed quickly at the place of use, for example, in the case of drugs, chemicals, food and beverages, disinfectants, strong detergents, agricultural chemicals, etc. In this regard, in order to overcome the disadvantages of containers known from the prior art, the present invention provides a container comprising a packaging container body in which at least two kinds of materials can be packed and sealed, said materials of at least two kinds, individually sealed and contained in the indicated case of the packaging container, can be quickly and automatically mixed without damaging the case during use.

The external plug heads of the internally mixed container and the releasable inner vessel of the present invention are helical mechanical cold plugs, hereinafter simply referred to as cold plugs. Compared to heat sealing, disclosed in PRC patent ZL200520051109.4 with publication number CN2805767Y and the title of the invention, “A large soft container for infusion with several cavities, containing a solid compartment for the drug, which can protect against light and prevent the penetration of oxygen into the filling its liquid and solid medicines ”, an advantage of the present invention is that cold sealing is carried out at room or low temperature so that fully preserve the active ingredients in the packaged materials in their original fresh condition. In contrast to this method, heat sealing in the above patent must be carried out at high temperature, which may adversely affect fresh active components in packaged materials near the place of sealing.

Regarding the method of internal mixing with the destruction of the diaphragm disclosed in the patent of the People's Republic of China No. ZL93241475.3 (publication number CN2191839Y, title of the invention, “Two-part membrane obtained by extrusion from raw materials”), and the method of internal mixing by punching an opening in aluminum foil, disclosed in PRC patent No. 95244597.2 (publication number CN2249214Y, title of the invention "Device for storing and adding reagents"), then both of them require the destruction or punching of any element, which leads to the possible introduction of particles azrushaemogo element into containers. The container with internal mixing and a releasable inner vessel of the present invention is characterized in that the internal mixing is carried out by rotating the outer head, leading to the release of the inner vessel and its falling into the container without destroying any elements of the container body. Thus, there is no danger of particles of various materials, the source of which are destructible elements, falling into the container, which guarantees the absence of contamination of materials packed in the container body with internal mixing.

SUMMARY OF THE INVENTION

The container of this invention consists of a container body, an external head, and an internal vessel. The external head has double walls, i.e. inner and outer walls of the outer head. Both the inner surface of the inner wall of the head and the inner surface of the outer wall of the head are threaded, and the thread on the inner surface of the outer wall of the head can be wound onto the thread that is provided with the outer surface of the neck of the container body. The thread on the inner surface of the inner wall of the head can be screwed onto the thread that is provided with the outer wall of the inner vessel. Below the thread on the outer wall of the inner vessel is a ratchet, the cams of which are in an orientation corresponding to the orientation of the ratchet on the inner wall of the neck of the container body. In addition, the inner wall of the head has an inner inclined surface in the lower part, and the corresponding part of the inner vessel has an external inclined surface.

During assembly, after the outer head and inner vessel are pressed end-to-end or threaded or bayonet-connected, a assembly jointly formed from the outer head and inner vessel will be inserted into the container body, and then the outer head will be tightened by rotation. From this moment, the outer head and inner vessel will be tightly connected to the container body, and the inner inclined surface of the inner wall of the head will abut against the outer inclined surface of the outer wall of the inner vessel, while the ratchet of the inner vessel will be tightly engaged with the cams on the inner wall of the neck of the container body. This completes the collection of the container with internal mixing and the released inner vessel.

For use, the outer head is unscrewed, however, the rotation of the inner vessel together with the outer head is prevented by tightly engaging the ratchet on the cams until the outer head simultaneously completes the threading of the neck of the container body with the inner vessel and the inner wall of the head completes the threading between them. At this moment, the inner vessel is freed from the outer head and falls into the container body under the action of gravity, which leads to automatic mixing of at least two types of materials in the container body.

The container body and the outer wall of the container head of the present invention are pressed against each other end-to-end and connected by thread or bayonet.

The upper part of the inner vessel and the inner wall of the head of the container of the present invention are butt-joined to each other and connected by thread or bayonet.

The outer head of the container can be placed anywhere in the body of the specified container.

The container of the present invention may be provided with one or more heads, as well as one or more internal vessels.

The configuration or shape of the indicated as well as the inner vessel may be arbitrarily selected.

The container of the present invention is a good packaging container with internal mixing, since the end-to-end connection and fastening of the container body, the external head and the inner vessel are carried out by means of a thread or a bayonet, so that various materials such as liquid material with liquid, liquid material with solid or solid material with solid, can be individually packed and enclosed in a common container, and mixing can be quickly performed inside the container. The internal mixing container of the present invention has a simple structure and is easy to manufacture, durable, inexpensive, and especially convenient to carry and use.

Since at least two materials are hermetically sealed and contained in the same container, when using the container with internal mixing and the released inner vessel of the present invention, it is guaranteed that the active components in these at least two types of materials will not be destroyed until instant preparation composition of them for use.

Due to these features, the container of the present invention is particularly suitable for packaging products comprising at least two types of materials, from which it is necessary to quickly prepare the composition and activate it at the place of work, in industries such as pharmaceuticals, food and beverages, chemicals, agricultural chemical products, disinfectants, as well as fire fighting equipment.

Due to these features, the container of the present invention can be used so that more and more new products can be used, from which it is necessary to quickly prepare the composition and activate it at the place of work, in industries such as pharmaceuticals, food and beverages, chemicals, agricultural chemicals products, disinfectants, and fire fighting equipment.

Brief Description of the Drawings

Figure 1 schematically shows the construction of a container with internal mixing and a released inner vessel.

Figure 2 schematically shows the assembled structure of the ratchet 5 and the cams 4 in the container.

Figure 3 schematically shows the design of a container used for separate packaging of sterile powder and a large volume of fluid for infusion, in which one released inner vessel is integrated into one container with internal mixing.

Figure 4 shows an industrial automatic process for filling a container in pharmaceuticals (sterile powder and a large volume of liquid for infusion or a sterile liquid and a large volume of liquid for infusion in a container with internal mixing).

5 schematically shows the construction of a container used for separate packaging of sterile fluid and a large volume of fluid for infusion, the sterile liquid drug being contained in the indicated inner vessel.

6 schematically shows the construction of a container used for separate packaging of two sterile powders and a large volume of fluid for infusion, in which two released internal vessels are integrated into one container with internal mixing.

Fig. 7 schematically shows the construction of a container used for separate packaging of sterile powder, sterile liquid and a large volume of infusion fluid, in which one released inner vessel containing sterile powder and one released inner vessel containing sterile liquid are integrated into one container with internal mixing.

Fig. 8 schematically shows the construction of a container used for separate packaging of two sterile fluids and a large volume of infusion fluid, in which two released internal vessels containing different liquid drugs are integrated into one container with internal mixing.

Fig.9 schematically shows the design of the container intended for food and drinks.

Figure 10 schematically shows the construction of a container for disinfectants and agricultural chemicals, in which three released internal vessels are integrated into one container with internal mixing.

11 schematically shows the construction of a container for chemical products or detergents, in which two released inner vessels are integrated into one container with internal mixing.

Description of preferred embodiments of the invention

A container with internal mixing and a releasable inner vessel of the present invention consists of a container body 1, an outer head 2 and an inner vessel 3. The outer head 2 has double walls, namely, the inner wall of the head 12 and the outer wall of the head 11. The inner vessel 3 is connected to the outer the head 2 by means of a thread MI, which is located on the upper part of the inner vessel 3 and on the inner wall of the head 12. Below the thread on the outer wall of the inner vessel 3 is a ratchet 5, the cams 4 being in position According to the orientation of the ratchet 5 on the inner wall of the neck of the container body 1. An MII thread is formed on the outer surface of the neck of the housing so that the container body 1 is tightly butt-welded and engaged with the outer wall of the head 11 of the outer head 2, and the inner vessel 3 is tightly connected butt and meshed with the inner wall of the head 12 of the outer head 2 by means of threads MI and MII, respectively. The inner inclined surface 13 is formed on the lower part of the inner wall of the head 12, and the outer inclined surface 14 is formed on the corresponding portion of the inner vessel 3. When the inner wall of the head 12 is tightly pressed end-to-end and connected to the inner vessel 3 by thread MI, the inner inclined surface 13 is tight pressed end-to-end to the outer inclined surface 14, resulting in increased sealing efficiency.

During assembly, after the outer head 2 and the inner vessel 3 are pressed end-to-end and threaded, the assembly formed from the outer head 2 and the inner vessel 3 is inserted into the container body 1. After that, the outer head is screwed on, with the assembly from the outer head 2 and the inner vessel 3 is tightly connected to the container body 1. In this case, the inner inclined surface 13 on the inner wall of the head 12 is pressed end-to-end against the outer inclined surface 14 of the outer wall of the inner vessel, while the ratchet 5 on the inner the vessel 3 is tightly engaged with the cams 4 on the inner wall of the neck of the container body. This completes the collection of the container with internal mixing and the released inner vessel.

In use, the outer head 2 is unscrewed, however, the rotation of the inner vessel 3 together with the outer head 2 is prevented due to the ratchet 5 and the cams 4 being engaged. When the outer head 2 extends beyond the stroke length of the MII thread on the neck of the container body, at the same time, the inner vessel 3 and the inner wall of the head 12 extend beyond the stroke length of the MI thread between them. At this moment, the inner vessel 3 is freed from the outer head 2 and falls inside the container body 1 under the action of gravity, which leads to automatic mixing of at least two types of materials in the container body 1.

Ratchet 5 and cams 4 can be designed in any shape, if this does not interfere with tight engagement and contact; the container body 1, the outer head 2 and the inner vessel 3 can be made of any shape.

Further, the present invention will be described in detail in the examples below.

Option 1

This embodiment relates to the use of a container with internal mixing and a releasable internal vessel in the pharmaceutical field (see FIG. 1, FIG. 2, FIG. 3 and FIG. 4).

In this case, the container with internal mixing and the released inner vessel consists of the container body 1, the outer head 2 and the inner vessel 3. The upper central part of the specified outer head 2 is hollow. The upper part of the inner vessel 3 is butt-joined and engaged with the inner wall 12 of the outer head 2 by means of a MI thread. The outer wall 11 of the outer head 2 is connected end-to-end and coupled to the container body 1 by means of an MII thread, see FIG. 3. Below the thread on the outer wall of the inner vessel 3 is a ratchet 5, the cams 4 being oriented in positions corresponding to the orientation of the ratchet 5 on the inner wall of the neck of the container body, see FIG. 2. An inner inclined surface 13 is formed on the lower part of the inner wall of the head 12, and an outer inclined surface 14 is formed on the corresponding portion of the inner vessel 3. When the inner wall of the head 12 is pressed firmly against the butt and is connected to the inner vessel 3 by thread MI, the inner inclined surface 13 is tight pressed end-to-end to the outer inclined surface 14 to increase the effectiveness of sealing, see Figure 3. The upper central part of the specified outer head 2 is closed with a rubber stopper 6. The assembly formed from the outer head 2 and the inner vessel 3 is packaged and sealed externally using foil 7, plastics, or other materials.

The body of the container 1 is made in the form of a cylindrical bottle made of polypropylene, metal or glass, the outer head 2 is a round head made of plastic, and the inner vessel 3 is a cylindrical bottle made of polypropylene. The principle of operation of this option can be explained as follows: a large volume of liquid for infusion is poured into the container body, usually a large volume of water, a large volume of glucose solution, a large volume of sodium chloride solution or a large volume of a mixed solution of glucose and sodium chloride (hereinafter simply referred to as large volume of fluid for infusion 9). The inner vessel 3 is filled with another type of drug. In this embodiment, the drug is a sterile powder 8. When using, remove the foil 7 and unscrew the outer head 2. Since the cams 4 on the inner wall of the neck of the container body are engaged with ratchet 5 on the outer wall of the inner vessel 3 to prevent rotation of the inner vessel 3 together with the outer head 2, the inner vessel 3 is separated from the outer head 2 and, under the action of gravity, falls inside the container body 1. At this point, the outer head is again twisted and the painting The container body 1 is formed, which leads to complete mixing of a large volume of infusion fluid 9 with sterile powder 8. In this technical solution, it is achieved that a large volume of infusion fluid 9 and sterile powder of the drug 8 are individually packed in the container body 1 and the inner vessel 3 during production, transportation and storage. However, the contents of the container body 1 and the inner vessel 3 will be quickly and automatically mixed immediately before use.

In order to use a container with internal mixing and a releasable internal vessel in pharmaceuticals, the corresponding industrial automatic filling line is described with reference to FIG. 4 as follows. The specified industrial line includes the following stages: manufacturing T1 bottles, disassembling T2 bottles, washing T3 bottles, filling a large amount of T4 infusion fluid, washing heads and internal vessels T5, sterilizing heads and internal vessels T6, assembling heads and internal vessels T6, inserting a unit from the head and internal vessel assembly T8, twisting the assembly from the head and internal vessel assembly and sealing T9, sterilization of a large volume of fluid for T10 infusion, leakage check on the T11 line, check with a T12 lamp, washing internal vessels T13, drying of internal vessels, T14, filling of internal vessels T15, washing of rubber tubes T16, sterilization of rubber tubes T17, insertion and pressing-in of rubber tubes T18, plugging of the head with foil T19, checking with a T20 lamp, marking and packaging of T21, etc. d. The procedure is characterized by the following features.

1. First, a large amount of fluid for infusion 9 is poured, then the final sterilization is performed (performed at stages T1-T12), followed by filling with sterile medicine and corking (performed at stages T13-T21). Filling with a large volume of fluid for T9 infusion, filling with sterile medicine and capping can be performed on a combined production line, moreover, a large volume of liquid for infusion and a sterile drug are introduced into the same container body, however, separate capping and packaging of a large volume of liquid for infusion 9 and another sterile drug.

2. This manufacturing process meets the requirements for the simultaneous production of large volumes of fluids for infusion and the production of sterile medicines. The final sterilization process is a common sterilization process for large volumes of infusion fluids, and the sterile drug filling process is also a common sterilization drug filling process.

3. Clogging T9 of a large volume of fluid for infusion 9 is performed separately from clogging T18 of a sterile drug, i.e. they are two separate blocking processes after filling with two different pharmaceuticals.

4. After a large volume of infusion fluid 9 and sterile drug powder 8 are filled in accordance with the above procedure, the external head is finally installed and sealed from the outside with foil 7, plastic or other materials that provide for weak areas or guides for simplicity removing or tearing the packaging used in order to gain access to the head for mixing sterile powder 8 and a large volume of infusion fluid 9.

5. Vacuum lyophilization technology is used to dry the internal T14 vessel on the line to ensure compliance with water content standards and sterile powder storage requirements.

Option 2

This embodiment relates to the use of a container with internal mixing and a releasable internal vessel in the pharmaceutical field (see FIG. 3, FIG. 4 and FIG. 5).

The difference between this option and option 1 is that the inner vessel 3 is filled with sterile liquid drug 10.

The difference between the two corresponding industrial automatic packaging lines in the pharmaceutical field is as follows: at the stage of drying the internal vessel T14, the line uses technology using sterilized heated air, while the quality requirements of sterile pharmaceutical liquid 10 are observed.

Option 3

This embodiment relates to the use of a container with internal mixing and a releasable internal vessel in the pharmaceutical field (see FIG. 3, FIG. 4 and FIG. 6).

The difference between this option and option 1 is that the container with internal mixing and the released inner vessel consists of a container body 1 and two external heads 2, two internal vessels 3 being inserted into the container body 1, and the upper part of each internal vessel 3 is connected with one outer head 2 via MI thread.

A large volume of fluid for infusion 9 is poured into the container body 1. The two indicated inner vessels 3 are filled with sterile pharmaceutical powder 8A and another sterile pharmaceutical powder 8B, respectively.

The difference between the two corresponding industrial automatic packaging lines in the pharmaceutical field is as follows: steps T1-T12 are performed to fill a large volume of T9 infusion fluid; To fill sterile powder 8A of the first inner vessel 3, steps T13-T20 are performed. According to the requirements of the rules for the organization of production and quality control of medicines (GMP), if sterile powders 8A and 8B can be packaged in separate containers on the same production line, then before filling the second inner vessel 3 with sterile pharmaceutical powder 8B, the filling line that used to fill the first inner vessel with 8A sterile powder, it must be washed, the surrounding area is cleaned, after which, in accordance with steps T13-T20, this same production line uses to be filled with 8B sterile pharmaceutical powder. In other words, after, in accordance with the described process, the first vessel 3 is filled with sterile powder 8A, the second sterile powder is filled in the same production line after the necessary washing and cleaning of the surrounding area in accordance with GMP requirements. According to GMP, if the sterile pharmaceutical powders 8A and 8B cannot be individually placed in the containers using the same production line, you need to add a second set of steps T13-T20 for the second sterile powder 8B, i.e. so that steps T13-T20 are performed for two inner vessels to be filled individually with sterile powders 8A and 8B on two production lines. After that, T21 is marked and packaged.

Option 4

This embodiment relates to the use of a container with internal mixing and a releasable internal vessel in the pharmaceutical field (see FIG. 3, FIG. 4 and FIG. 7).

The difference between this option and option 3 is that the container body 1 is filled with a large volume of fluid for infusion 9, and then the two inner vessels 3 are filled with sterile pharmaceutical powder 8 and sterile liquid drug 10, respectively.

The difference between the two corresponding industrial automatic packaging lines in the medical field is as follows: to fill a large volume of fluid for infusion 9, steps T1-T12 are performed; to fill the first inner vessel 3 with sterile pharmaceutical powder 8, steps T13-T20 are performed. To fill the second inner vessel 3 with sterile liquid drug 10, it is necessary to add a second set of steps T13-T20 to fill with the indicated sterile liquid, i.e. filling of two inner vessels with sterile powder 8 and sterile liquid 10 should be performed sequentially on two production lines T13-T20. After that, T21 is marked and packaged.

Drying with sterilized hot air in the case of a sterile liquid and vacuum lyophilization technology in the case of a sterile powder are used as the drying technology for the inner vessel T14.

Option 5

This embodiment relates to the use of a container with internal mixing and a releasable internal vessel in the pharmaceutical field (see FIG. 3, FIG. 4 and FIG. 8).

The difference between this option and option 3 is that the two inner vessels 3 are separately filled with two sterile pharmaceutical liquids 10.

A large volume of fluid for infusion 9 is poured into the container body 1. Two of these internal vessels 3 are filled with sterile liquid drug 10A and another sterile liquid 10B, respectively.

The difference between the two corresponding industrial automatic packaging lines in the pharmaceutical field is as follows: steps T1-T12 are performed to fill a large volume of T9 infusion fluid; to fill the first inner vessel 3 with sterile liquid 10A, steps T13-T20 are performed. According to the requirements of the rules for the organization of production and quality control of medicines (GMP), if sterile liquids 10A and 10B can be filled individually in containers on the same production line, then before filling the second inner vessel 3 with sterile liquid 10B, the filling line that used to fill the first inner vessel 3 with sterile liquid 10A, it must be washed, the surrounding area is cleaned, after which, in accordance with steps T13-T20, this same production line is used to fill filling with sterile liquid 10B. In other words, after, in accordance with the described process, the first vessel 3 is filled with sterile liquid 10A, the second sterile liquid can be filled in the same production line, if necessary after the required washing and cleaning of the surrounding area in accordance with GMP requirements. According to GMP, if the sterile pharmaceutical fluids 10A and 10B cannot be individually poured into containers using the same production line, you must add a second set of steps T13-T20 for the second sterile fluid 10B, i.e. for two internal vessels for filling with sterile fluids, 10A and 10B are filled separately on two T13-T20 production lines. After that, T21 is marked and packaged.

To dry the internal vessel T14 on the line, a technology using sterilized heated air is used in compliance with the quality requirements of sterile pharmaceutical liquid 10.

Option 6

This option relates to the use of a container with internal mixing and a released inner vessel for food and beverages (see Figure 1, Figure 2 and Figure 9).

As shown in FIG. 9, when applying the present invention in the field of food products and beverages (functional beverages), drinking mineral water, pure water or distilled water is poured into the container body 1. In the inner vessel 3 contains a nutrient solution or a culture of beneficial bacteria, and the nutrient solution is a functional plant extract (powder), honey, honey vinegar or honey paste. In use, the outer head 2 is unscrewed, while the inner vessel 3 automatically falls into the body of the container 1, so that the functional drink is mixed independently.

Option 7

This option relates to the use of a container with internal mixing and a released inner vessel for disinfectants and agricultural chemicals (see Figure 1, Figure 2 and Figure 10).

As shown in FIG. 10, when applying the present invention to self-mixing disinfectants or instant agricultural chemicals, the invention can be implemented in such a way that one or more external heads 2 are screwed onto the container body 1 from the outside, and accordingly one or more internal vessels 3, in order to realize activation and rapid preparation of a composition of two or more materials in one container body 1 (two are integrated into one container three, four, etc. internal vessels).

When using a container with internal mixing and a released inner vessel for disinfectants (or pesticides), the container body 1 is filled with a solution or ordinary water, and the other active component a, b, c ... is contained in the corresponding internal vessels 3 A, B, C ... c powder or liquid. During use, the external heads 2 D, E, F ... rotate in turn, so that the corresponding inner vessels 3 automatically fall inside the container body 1 and self-mixing and quick preparation of the required composition is achieved.

Option 8

This embodiment relates to the use of a container with internal mixing with a released inner vessel in the field of chemical products and detergents (see FIG. 1, FIG. 2 and FIG. 11).

As shown in FIG. 11, when the present invention is implemented as a container with internal mixing and a releasable inner vessel for chemical products and detergents, water or other reagents are poured into the container body 1, and other chemical products (active components, catalysts) a, b ... in the form of powders or liquids are placed in the corresponding inner vessels 3 A, B .... During use, when the corresponding external heads 2 D, E ... are rotated, the corresponding inner vessels 3 automatically fall inside the container body 1 and self-mixing and fast preparation of the required composition are achieved.

It should be noted that a specialist in the relevant field will be able to make many modifications or changes to the above options of the present invention without changing its essence. Therefore, it must be understood that the invention is not limited to the specific embodiments disclosed therein, and is intended to encompass all modifications and / or changes relating to it in accordance with the claims.

Claims (21)

1. A container with internal mixing and a releasable inner vessel, consisting of a container body (1), an external head (2) and an internal vessel (3), wherein different types of materials are independently contained in the container body (1) and the internal vessel (3), and the specified external head (2) has an inner wall of the head (12) and an outer wall of the head (11), characterized in that:
the inner vessel (3) is tightly pressed end-to-end and connected to the outer head (2) by means of a thread (Ml) or a bayonet between the upper part of the outer wall of the inner vessel (3) and the inner wall of the head (12), forming a node from the inner vessel (3) and external head (2); in addition, a thread or a bayonet is provided on the outer wall of the head (11) for tight butt pressing and connection with the neck of the container body (1); as well as
a ratchet (5) is provided on the outer wall of the inner vessel (3), and cams (4) are provided on the inner wall of the neck portion of the container body (1) in a position corresponding to the position of the ratchet (5), and the indicated ratchet and cams are selected in such a way to prevent rotation of the inner vessel (3) together with the outer head due to the engagement of the ratchet (5) with the cams (4) when unscrewing the outer head (2) after the assembled assembly is inserted into the neck of the container body (1) and the outer head is screwed ka (2); wherein the inner vessel (3) is separated from the outer head (2), and the inner vessel (3) falls into the container body (1) under the action of gravity. 2. The container according to claim 1, characterized in that the ratchet (5) is located in the area below the thread (Ml) on the outer wall of the inner vessel (3). 3. The container according to claim 1, characterized in that the inner vessel (3) and the inner wall of the head (12) extend beyond the length of the thread (M1) between them simultaneously so that the outer head (2) extends beyond the length of the thread on the neck of the container body. 4. The container according to claim 1, characterized in that the materials contained in the container body (1) and in the inner vessel (3) are gaseous, liquid or solid. 5. The container according to claim 1, characterized in that at least one external head (2) is present on any part of the body, and one internal vessel (3) corresponds to each external head (2). 6. The container according to claim 1, characterized in that an inner inclined surface (13) is formed on the lower part of the inner wall of the head (12), an outer inclined surface (14) is formed in the corresponding section of the inner vessel (3), and when the inner wall of the head (12) presses tightly against the butt and engages with the inner vessel (3) by means of a thread, the inner inclined surface (13) presses tightly against the outer inclined surface (14) to increase the sealing efficiency. 7. The container according to claim 1, characterized in that the outer head (2) and the neck of the container body (1) have a circular cross section. 8. The container according to claim 1, characterized in that the container body (1) is made of a polymer, metal material or glass, and the inner vessel (3) is made of a polymer material. 9. The container according to claim 8, characterized in that the container body (1) is made of polypropylene or polyethylene and the inner vessel (3) is made of polypropylene or polyethylene. 10. The container according to claim 1, characterized in that the external head (2) is hollow in the upper central part, through which the inner vessel (3) is filled, and the external head (2) is equipped with a rubber stopper (6) to seal it with a hollow central part. 11. The container according to claim 10, characterized in that the outer head (2) and the rubber stopper (6) are packaged and sealed as a unit by means of foil (7) or plastic, provided with weak sections or guides. 12. The container according to any one of claims 1 to 11, intended for use in the field of pharmaceuticals, food and beverages, chemicals, agricultural chemicals, disinfectants or detergents. 13. The container according to claim 1, characterized in that the container body (1) contains liquid, and in the inner vessel (3) contains liquid or solid drugs. 14. The container according to claim 1, characterized in that the container body (1) contains drinking mineral water, pure water or distilled water, and in the inner vessel (3) contains a nutrient solution or culture of beneficial bacteria. 15. The container of claim 14, wherein said nutrient solution is a functional plant extract (powder), honey, honey vinegar, or honey paste. 16. The method of filling the container with internal mixing and the released inner vessel according to claim 1, used for infusion of large volumes in the pharmaceutical field, comprising the following steps:
making bottles (T1), disassembling bottles (T2), washing bottles (T3), pouring a large amount of fluid for infusion (T4), washing the external heads and internal vessels (T5), sterilizing the external heads and internal vessels (T6), assembling the external the head and inner vessel (T7), insert the assembly from the head and inner vessel assembly (T8), tighten the assembly from the head and inner vessel assembly and sealing (T9), the final sterilization of a large volume of fluid for infusion (T10), check for leakage lines (T11), check with a lamp (T12), internal wash vessel (T13), drying the inner vessel (T14), filling the inner vessel through the top (T15), washing the rubber plugs (T16), sterilizing the rubber plugs (T17), inserting and fitting rubber plugs (T18), clogging the head with foil (T 19). 17. The method according to clause 16, characterized in that at first a large volume of fluid for infusion (9) is poured into the container body (1), and after its final sterilization, the inner vessels (3) are filled with other active pharmaceutical components and corked, filling the container body (1) with a large volume of fluid for infusion (9) and filling with at least one pharmaceutical component of the inner vessel (3) and corking it is carried out in a combined production line, so that the volume of fluid for infusion (9) and hile least one pharmaceutical component are sealed and packaged in the same container body (1), respectively. 18. The method according to clause 16, wherein the sterilization process is a common sterilization process for large volumes of infusion fluids, and the process of filling and capping active pharmacological components is a common process for filling and capping sterile pharmacological components. 19. The method according to clause 16, characterized in that when each inner vessel (3) is added to the container, the inner vessel is washed (T13), the inner vessel is dried (T14), the inner vessel is filled (T15), the rubber plugs are washed (T16) sterilization of rubber plugs (T17), insertion and pressing-in of rubber plugs (T18), sealing of the head with foil (T19). 20. The method according to clause 16, characterized in that if the pharmaceutical component is a liquid, the drying of the inner vessel (T14) is carried out using sterilized heated air. 21. The method according to clause 16, characterized in that if the pharmaceutical component is solid, the drying of the inner vessel (T14) is carried out by vacuum lyophilization.

Images