RU2360715C1 - Pityriasis rosea (gibert's disease) treatment method - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: pityriasis rosea (Gibert's disease) treatment involves coating of the affected skin surface with Radochlorine gel 0.1% dosed 0.2 per 1 cm of the surface. Exposure of photosensitiser is 2 hours under a lightproof bandage. After gel is removed, the surface is exposure to laser light at wavelength 662 nm and light energy dose 200 J/cm. The exposure is contactless. The laser light source is a diode laser apparatus for photodynamic therapy "LAHTA-MILON".

EFFECT: reduced recovery time, prolonged recurrence-free period and high cosmetic effect of treatment.

2 cl, 2 ex

Description

The invention relates to medicine, namely to photodynamic therapy, and can be used to treat pink lichen (Giber disease).

The prototype of the invention is a method for the treatment of pink lichen with drugs (B.A. Berenbein, A.A. Studnitsin. Differential diagnosis of skin diseases. / - M .: Medicine, 1989. - 672 p .; Skin and sexually transmitted diseases. Ed. About .K.Shaposhnikova. / - M .: Medicine, 1985. - 368 p.). However, with this method, therapeutic efficacy and a high recurrence rate of the disease remain low.

The technical result is a reduction in recovery time, an increase in the relapse-free period and a high cosmetic effect of the treatment.

The specified technical result is achieved due to the fact that 0.1% Radochlorin gel is applied to the affected skin surface at a dose of 0.2 g per 1 cm ^{2 of the} surface, exposure for 2 hours under a lightproof dressing, and after removing the gel, the surface is treated with laser light with a wavelength of 662 nm at a dose of light energy of 200 J / cm ² , while the effect is contactless. As a source of laser radiation using a diode laser apparatus for photodynamic therapy "LAHTA-MILON".

The proposed method for the treatment of pink lichen (Giber disease) is carried out as follows: a 0.1% Radochlorin gel is applied to the entire affected surface and covered with a lightproof dressing. After 2 hours of exposure, the lightproof dressing is removed, excess gel is removed with a gauze and the surface is treated with laser light at a wavelength of 662 nm at a dose of light energy of 200 J / cm ² , the effect is contactless using a light guide with a microlens. Treatment is carried out once.

Dynamic monitoring is carried out after 1 week, 10 days, 1 month, 6 months and 12 months after treatment.

The authors in the patent and medical literature did not find information about the fame of the proposed method for the treatment of pink lichen using photodynamic therapy. Thus, the claimed invention meets the criterion of "novelty."

The authors found for the first time that the above set of distinguishing features of the method causes a quick and steady disappearance of disseminated rashes, a decrease in the recovery time, an increase in the relapse-free period and a high cosmetic effect of treatment, which makes it possible to obtain the indicated technical result. Thus, the claimed invention meets the criterion of "inventive step".

The proposed method is illustrated by the following examples.

Example 1. Patient N., 18 years old. Complaints on admission to the rash of an oval shape on the chest, back and limbs. Considers himself ill for about three years. Marks the seasonality of rashes, usually in spring. In the center of the spots, slightly noticeable dry folded scales are revealed, and on the periphery there is a red border free of scales. Slight itching in the affected areas. On the basis of the anamnesis and clinical picture, the patient was diagnosed with pink lichen (Giber disease).

The patient received the following treatment. A 0.1% Radochlorin gel at a dose of 0.2 g per 1 cm ^{2 was} applied to the entire affected surface of the skin and covered with a lightproof dressing. After 2 hours of exposure, the lightproof dressing was removed, excess gel was removed with a gauze and once the entire affected surface was treated with laser light at a wavelength of 662 nm at a dose of light energy of 200 J / cm ² . The exposure was carried out contactlessly using a light guide with a microlens. At the control examination 1 week after the treatment session, the patient does not show complaints. Skin areas subjected to photodynamic therapy are clean, without signs of damage. Control inspection after 10 days. The patient has no complaints. The skin is clean. Control examination after 1 month - no complaints, the entire surface treated without signs of damage. At the follow-up examination after 6 months, the patient does not complain, the treated areas are clean. Control examination 12 months after treatment - no complaints, the skin is clean, without signs of activation of the process.

Example 2. Patient C., 38 years old. Complaints upon receipt of a rash of pink-red color throughout the body and limbs, mild itching in the affected areas. Considers herself ill for about four years. On examination, the surface of the rashes is covered with small, bran-shaped scales, a pronounced red border, free of scales, on the periphery. On the basis of the anamnesis and clinical picture, the patient was diagnosed with pink lichen (Giber disease). A 0.1% Radochlorin gel at a dose of 0.2 g per 1 cm ^{2 of the} surface was applied to the patient on the entire affected surface. After that, the affected areas were covered with a lightproof dressing. After 2 hours of exposure, the light-tight bandage was removed and excess gel was removed with a gauze. After that, all affected areas of the skin were treated with laser light at a wavelength of 662 nm at a dose of light energy of 200 J / cm ² , the treatment was carried out with a light guide with a microlens, non-contact. At the control examination 1 week after the treatment session, the patient does not show complaints. Skin areas subjected to photodynamic therapy are clean. Control inspection after 10 days. The patient has no complaints. The skin is clean. Control examination after 1 month - no complaints, the skin is clean without signs of damage. At the follow-up examination after 6 months, the patient does not complain, the treated skin areas are clean. Control examination 12 months after treatment - no complaints, the skin is clean, without signs of activation of the process. Relapse of the disease was not observed.

This method treated 12 patients with a diagnosis of pink lichen. In all cases, the specified technical result was achieved. The proposed method is easily reproducible in a polyclinic and a hospital. Thus, the claimed invention meets the criterion of "industrial applicability".

Claims (2)

1. A method for the treatment of pink lichen (Giber disease), characterized in that 0.1% Radochlorin gel is applied to the affected skin surface at a dose of 0.2 g per 1 cm of surface, 2 hours exposure under a lightproof dressing, and after removing the gel treat the surface with laser light at a wavelength of 662 nm at a dose of light energy of 200 J / cm ² , while the effect is carried out non-contact. 2. The method according to claim 1, characterized in that as a source of laser radiation using a diode laser apparatus for photodynamic therapy "LAHTA-MILON".