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PT98464A - PROCESS FOR THE PREPARATION OF CYCLOPENTAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

PROCESS FOR THE PREPARATION OF CYCLOPENTAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
PT98464A
PT98464A PT98464A PT9846491A PT98464A PT 98464 A PT98464 A PT 98464A PT 98464 A PT98464 A PT 98464A PT 9846491 A PT9846491 A PT 9846491A PT 98464 A PT98464 A PT 98464A
Authority
PT
Portugal
Prior art keywords
derivatives
cyclopentan
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
PT98464A
Other languages
Portuguese (pt)
Other versions
PT98464B (en
Inventor
Helmut Vorbruggen
Ulrich Klar
Hartmut Rehwinkel
Karl-Heinz Thierauch
Peter Verhallen
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of PT98464A publication Critical patent/PT98464A/en
Publication of PT98464B publication Critical patent/PT98464B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to cyclopentane derivatives of formula (I) and their salts with physiologically tolerables bases and the $g(a), $g(b) or $g(g)-cyclodextrin clathrates and the liposome-encapsulated compounds of formula (I), a process for producing them and their pharmaceutical use.
PT98464A 1990-07-27 1991-07-26 PROCESS FOR THE PREPARATION OF CYCLOPENTAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PT98464B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4024347A DE4024347A1 (en) 1990-07-27 1990-07-27 CYCLOPENTANE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR PHARMACEUTICAL USE

Publications (2)

Publication Number Publication Date
PT98464A true PT98464A (en) 1992-05-29
PT98464B PT98464B (en) 1997-10-31

Family

ID=6411402

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98464A PT98464B (en) 1990-07-27 1991-07-26 PROCESS FOR THE PREPARATION OF CYCLOPENTAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (13)

Country Link
EP (1) EP0541594B1 (en)
JP (1) JPH06502390A (en)
AT (1) ATE122036T1 (en)
AU (1) AU8221291A (en)
CA (1) CA2088161A1 (en)
DE (3) DE4024347A1 (en)
DK (1) DK0541594T3 (en)
ES (1) ES2074721T3 (en)
IE (1) IE67507B1 (en)
IL (1) IL98970A0 (en)
PT (1) PT98464B (en)
WO (1) WO1992002495A1 (en)
ZA (1) ZA915905B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4036140A1 (en) * 1990-11-09 1992-05-14 Schering Ag 9-HALOGEN-11SS-HYDROXY-PROSTAGLANDIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
AU687906B2 (en) * 1993-12-15 1998-03-05 Alcon Laboratories, Inc. Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension
JP2001515882A (en) * 1997-09-09 2001-09-25 ザ プロクター アンド ギャンブル カンパニー Aromatic C16-C20 substituted tetrahydroprostaglandins useful as FP agonists
TR200000673T2 (en) * 1997-09-09 2000-11-21 The Procter & Gamble Company Aromatic C16-C20-substituted tetrahydro prostaglandins useful as FP agonists.
PL339213A1 (en) * 1997-09-09 2000-12-04 Procter & Gamble Aromatic c16-c20-substituted tetrahydroprostaglandines useful as fp agonists
EP1071648A2 (en) * 1998-03-13 2001-01-31 Merck Frosst Canada & Co. Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment
US6242493B1 (en) 1998-03-13 2001-06-05 Merck Frosst Canada & Co. Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment
CN1350521A (en) 1999-03-05 2002-05-22 宝洁公司 C16 unsaturated FP-selective prostaglanding analogs
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US7323591B2 (en) * 2006-01-10 2008-01-29 Allergan, Inc. Substituted cyclopentanes or cyclopentanones as therapeutic agents
CA2724271A1 (en) 2008-05-15 2009-11-19 Allergan, Inc. Therapeutic substituted cyclopentanes
CN102336754B (en) * 2010-07-15 2017-04-12 浙江奥翔药业股份有限公司 Method for synthesizing entecavir and intermediate compound thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1431561A (en) * 1973-01-31 1976-04-07 Ici Ltd Cyclopentane derivatives
IT1053781B (en) * 1974-09-25 1981-10-10 Erba C S P A Ora Farmitalia OMEGA NOR CICLOALCIL 13.14 DEIDRO PROSTAGLANDINE
FR2349328A1 (en) * 1976-04-30 1977-11-25 Roussel Uclaf (11)-Deoxy-prostaglandin analogues - for use as hypotensives, smooth-muscle contractants and luteolytic agents
DE3126924A1 (en) * 1981-07-03 1983-01-20 Schering Ag, 1000 Berlin Und 4619 Bergkamen 9-FLUOR PROSTAGLAND DERIVATIVES, METHOD FOR THE PRODUCTION AND USE AS A MEDICINAL PRODUCT
DE3325175A1 (en) * 1983-07-08 1985-01-17 Schering AG, 1000 Berlin und 4709 Bergkamen 11-HALOGEN PROSTANE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
DE3510978A1 (en) * 1985-03-22 1986-09-25 Schering AG, Berlin und Bergkamen, 1000 Berlin NEW 9-HALOGEN PROSTAGLANDINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
ES2054860T5 (en) * 1987-07-17 2003-11-01 Schering Ag DERIVATIVES OF 9-HALOGEN- (Z) -PROSTAGLANDINAS, PROCEDURE FOR ITS PREPARATION AND ITS USE AS MEDICATIONS.
DE3923797A1 (en) * 1989-07-14 1991-01-24 Schering Ag 9-FLUOR-PROSTAGLANDIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR PHARMACEUTICAL USE

Also Published As

Publication number Publication date
DE59105400D1 (en) 1995-06-08
WO1992002495A1 (en) 1992-02-20
EP0541594B1 (en) 1995-05-03
AU8221291A (en) 1992-03-02
CA2088161A1 (en) 1992-01-28
IE67507B1 (en) 1996-04-03
JPH06502390A (en) 1994-03-17
IL98970A0 (en) 1992-07-15
IE912654A1 (en) 1992-01-29
ES2074721T3 (en) 1995-09-16
EP0541594A1 (en) 1993-05-19
ZA915905B (en) 1992-04-29
ATE122036T1 (en) 1995-05-15
DK0541594T3 (en) 1995-10-02
DE4024347A1 (en) 1992-01-30
DE4191848D2 (en) 1993-10-07
PT98464B (en) 1997-10-31

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Legal Events

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BB1A Laying open of patent application

Effective date: 19920128

FG3A Patent granted, date of granting

Effective date: 19970707

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20000131

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