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PL3018145T3 - Środki i sposoby leczenia chłoniaka rozlanego z dużych komórek B (DLBCL) - Google Patents

Środki i sposoby leczenia chłoniaka rozlanego z dużych komórek B (DLBCL)

Info

Publication number
PL3018145T3
PL3018145T3 PL15195076T PL15195076T PL3018145T3 PL 3018145 T3 PL3018145 T3 PL 3018145T3 PL 15195076 T PL15195076 T PL 15195076T PL 15195076 T PL15195076 T PL 15195076T PL 3018145 T3 PL3018145 T3 PL 3018145T3
Authority
PL
Poland
Prior art keywords
methods
treating dlbcl
dlbcl
treating
Prior art date
Application number
PL15195076T
Other languages
English (en)
Inventor
Gerhard Zugmaier
Dirk Nagorsen
Juergen Scheele
Original Assignee
Amgen Research (Munich) Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45023802&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3018145(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Research (Munich) Gmbh filed Critical Amgen Research (Munich) Gmbh
Publication of PL3018145T3 publication Critical patent/PL3018145T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Carbon And Carbon Compounds (AREA)
PL15195076T 2010-10-27 2011-10-27 Środki i sposoby leczenia chłoniaka rozlanego z dużych komórek B (DLBCL) PL3018145T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40710710P 2010-10-27 2010-10-27
EP11787633.4A EP2632954B2 (en) 2010-10-27 2011-10-27 Means and methods for treating dlbcl
EP15195076.3A EP3018145B1 (en) 2010-10-27 2011-10-27 Means and methods for treating dlbcl

Publications (1)

Publication Number Publication Date
PL3018145T3 true PL3018145T3 (pl) 2018-09-28

Family

ID=45023802

Family Applications (3)

Application Number Title Priority Date Filing Date
PL15195076T PL3018145T3 (pl) 2010-10-27 2011-10-27 Środki i sposoby leczenia chłoniaka rozlanego z dużych komórek B (DLBCL)
PL18164175T PL3412687T3 (pl) 2010-10-27 2011-10-27 Sposoby leczenia dlbcl
PL11787633T PL2632954T5 (pl) 2010-10-27 2011-10-27 Środki i sposoby leczenia DLBCL

Family Applications After (2)

Application Number Title Priority Date Filing Date
PL18164175T PL3412687T3 (pl) 2010-10-27 2011-10-27 Sposoby leczenia dlbcl
PL11787633T PL2632954T5 (pl) 2010-10-27 2011-10-27 Środki i sposoby leczenia DLBCL

Country Status (32)

Country Link
US (2) US9192665B2 (pl)
EP (3) EP2632954B2 (pl)
JP (3) JP5997168B2 (pl)
KR (1) KR101889995B1 (pl)
CN (2) CN105251003B (pl)
AU (1) AU2011322581B2 (pl)
CA (1) CA2815119C (pl)
CL (1) CL2013001138A1 (pl)
CR (1) CR20130245A (pl)
CY (3) CY1117155T1 (pl)
DK (3) DK3412687T3 (pl)
EA (1) EA032139B1 (pl)
ES (3) ES2787044T3 (pl)
HK (1) HK1188229A1 (pl)
HR (2) HRP20151444T4 (pl)
HU (3) HUE037786T2 (pl)
IL (3) IL225924A (pl)
LT (2) LT3412687T (pl)
MA (1) MA34619B1 (pl)
ME (1) ME02311B (pl)
MY (1) MY163057A (pl)
NZ (2) NZ609201A (pl)
PH (1) PH12013500826A1 (pl)
PL (3) PL3018145T3 (pl)
PT (3) PT3018145T (pl)
RS (3) RS60094B1 (pl)
SG (1) SG189869A1 (pl)
SI (3) SI2632954T2 (pl)
SM (3) SMT201800319T1 (pl)
TR (1) TR201808019T4 (pl)
UA (1) UA111175C2 (pl)
WO (1) WO2012055961A1 (pl)

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DK1874821T3 (da) 2005-04-26 2013-07-08 Trion Pharma Gmbh Kombination af antistoffer med glykokortikoider til behandling af kræft
ES2787044T3 (es) * 2010-10-27 2020-10-14 Amgen Res Munich Gmbh Métodos para tratar LDCBG
EP3831386A1 (en) 2010-11-10 2021-06-09 Amgen Research (Munich) GmbH Prevention of adverse effects caused by cd3 specific binding domains
JO3529B1 (ar) * 2013-02-08 2020-07-05 Amgen Res Munich Gmbh مضاد التصاق خلايا الدم البيض من أجل التخفيف من الاثار السلبية الممكنة الناتجة عن مجالات ارتباط cd3- المحدد
EP3057994B1 (en) 2013-10-15 2020-09-23 The Scripps Research Institute Peptidic chimeric antigen receptor t cell switches and uses thereof
WO2016154621A1 (en) 2015-03-26 2016-09-29 The California Institute For Biomedical Research SWITCHABLE NON-scFv CHIMERIC RECEPTORS, SWITCHES, AND USES THEREOF
WO2016168773A2 (en) 2015-04-15 2016-10-20 The California Institute For Biomedical Research Optimized pne-based chimeric receptor t cell switches and uses thereof
IL255697B2 (en) 2015-05-18 2023-11-01 Tcr2 Therapeutics Inc Compositions and methods for tcr reprogramming using fusion proteins
IL299203A (en) * 2015-10-13 2023-02-01 Eureka Therapeutics Inc ׂ A Delaware Corp Antibody factors specific for human differentiation group 19 and their uses
JP2019532017A (ja) * 2016-07-14 2019-11-07 フレッド ハッチンソン キャンサー リサーチ センター がんを治療するための異なるエピトープ結合を示す複数の二重特異性結合ドメイン構築物
JP7109789B2 (ja) 2016-08-02 2022-08-01 ティーシーアール2 セラピューティクス インク. 融合タンパク質を使用したtcrの再プログラム化のための組成物及び方法
WO2018067993A1 (en) 2016-10-07 2018-04-12 TCR2 Therapeutics Inc. Compositions and methods for t-cell receptors reprogramming using fusion proteins
JP7149935B2 (ja) 2016-10-19 2022-10-07 ザ スクリプス リサーチ インスティテュート ヒト化された標的化部分および/または最適化されたキメラ抗原受容体相互作用ドメインを有する、キメラ抗原受容体エフェクター細胞スイッチ、ならびにその使用
CN110177803A (zh) 2016-11-22 2019-08-27 T细胞受体治疗公司 用于使用融合蛋白进行tcr重新编程的组合物和方法
US10537585B2 (en) 2017-12-18 2020-01-21 Dexcel Pharma Technologies Ltd. Compositions comprising dexamethasone
WO2019133847A1 (en) 2017-12-29 2019-07-04 Oncorus, Inc. Oncolytic viral delivery of therapeutic polypeptides
WO2020099513A1 (en) * 2018-11-13 2020-05-22 Lipoxen Technologies Limited Glycopolysialylation of blinatumomab
AU2020267378B2 (en) * 2019-05-03 2025-01-30 Kite Pharma, Inc. Methods of administering chimeric antigen receptor immunotherapy
WO2020232247A1 (en) 2019-05-14 2020-11-19 Provention Bio, Inc. Methods and compositions for preventing type 1 diabetes
US12221481B2 (en) 2019-05-21 2025-02-11 Novartis Ag CD19 binding molecules and uses thereof
US12006366B2 (en) 2020-06-11 2024-06-11 Provention Bio, Inc. Methods and compositions for preventing type 1 diabetes
CA3204063A1 (en) * 2020-12-04 2022-06-09 Morphosys Ag Anti-cd19 combination therapy
EP4284512B1 (en) 2021-01-28 2025-03-26 Regeneron Pharmaceuticals, Inc. Compositions and methods for treating cytokine release syndrome
KR20250004700A (ko) 2022-04-11 2025-01-08 리제너론 파마슈티칼스 인코포레이티드 보편적 종양 세포 사멸을 위한 조성물 및 방법
WO2024173830A2 (en) 2023-02-17 2024-08-22 Regeneron Pharmaceuticals, Inc. Induced nk cells responsive to cd3/taa bispecific antibodies

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02500329A (ja) 1987-05-21 1990-02-08 クリエイテイブ・バイオマリキユールズ・インコーポレーテツド ターゲット化多機能蛋白質
KR100508289B1 (ko) 1998-04-21 2005-08-17 마이크로메트 에이지 Cd19×cd3 특이 폴리펩티드 및 그의 용도
US7635472B2 (en) 2003-05-31 2009-12-22 Micromet Ag Pharmaceutical compositions comprising bispecific anti-cd3, anti-cd19 antibody constructs for the treatment of b-cell related disorders
AU2004293182B2 (en) 2003-11-28 2010-02-18 Amgen Research (Munich) Gmbh Compositions comprising polypeptides
KR101289537B1 (ko) 2005-02-15 2013-07-31 듀크 유니버시티 항-cd19 항체 및 종양학에서 이의 용도
DK1874821T3 (da) * 2005-04-26 2013-07-08 Trion Pharma Gmbh Kombination af antistoffer med glykokortikoider til behandling af kræft
CN101331151A (zh) * 2005-12-16 2008-12-24 麦克罗梅特股份公司 治疗肿瘤性疾病的方式和方法
ES2532124T3 (es) * 2005-12-16 2015-03-24 Amgen Research (Munich) Gmbh Medios y procedimientos para el tratamiento de enfermedades tumorales
EP2066349B1 (en) 2006-09-08 2012-03-28 MedImmune, LLC Humanized anti-cd19 antibodies and their use in treatment of tumors, transplantation and autoimmune diseases
CN109456410B (zh) 2007-04-03 2022-01-28 安进研发(慕尼黑)股份有限公司 跨物种特异性CD3-ε结合结构域
AU2009313040B2 (en) * 2008-11-07 2015-07-09 Amgen Research (Munich) Gmbh Treatment of acute lymphoblastic leukemia
JP6092625B2 (ja) 2009-10-27 2017-03-08 アムゲン リサーチ (ミュンヘン) ゲーエムベーハー CD19xCD3二重特異性抗体を投与するための投与計画
ES2787044T3 (es) * 2010-10-27 2020-10-14 Amgen Res Munich Gmbh Métodos para tratar LDCBG

Also Published As

Publication number Publication date
CN103459425B (zh) 2015-11-25
US20130287778A1 (en) 2013-10-31
ES2563439T3 (es) 2016-03-15
EA032139B1 (ru) 2019-04-30
HRP20151444T4 (hr) 2021-08-20
LT3018145T (lt) 2018-05-10
CN105251003B (zh) 2019-08-02
SMT201600050B (it) 2016-04-29
PT3412687T (pt) 2020-04-03
HK1188229A1 (zh) 2014-04-25
IL225924A (en) 2017-12-31
HUE048639T2 (hu) 2020-08-28
HUE037786T2 (hu) 2018-09-28
EA201390387A1 (ru) 2013-10-30
SMT201800319T1 (it) 2018-07-17
RS54525B1 (en) 2016-06-30
AU2011322581B2 (en) 2015-04-23
SI3018145T1 (en) 2018-08-31
IL225924A0 (en) 2013-06-27
HUE027678T2 (en) 2016-11-28
ES2675299T3 (es) 2018-07-10
KR20140019298A (ko) 2014-02-14
DK3018145T3 (en) 2018-05-28
CY1117155T1 (el) 2017-04-05
JP6254220B2 (ja) 2017-12-27
WO2012055961A1 (en) 2012-05-03
CN103459425A (zh) 2013-12-18
JP6522722B2 (ja) 2019-05-29
CR20130245A (es) 2013-09-20
JP5997168B2 (ja) 2016-09-28
NZ609201A (en) 2015-01-30
EP3018145A1 (en) 2016-05-11
UA111175C2 (uk) 2016-04-11
NZ719768A (en) 2021-07-30
PT2632954E (pt) 2016-02-03
US20160208001A1 (en) 2016-07-21
US9192665B2 (en) 2015-11-24
SI3412687T1 (sl) 2020-07-31
EP2632954A1 (en) 2013-09-04
TR201808019T4 (tr) 2018-06-21
PH12013500826A1 (en) 2013-06-17
HRP20180882T1 (hr) 2018-07-27
EP3412687B1 (en) 2020-03-18
RS57260B1 (sr) 2018-08-31
NZ701715A (en) 2016-05-27
SG189869A1 (en) 2013-06-28
LT3412687T (lt) 2020-07-27
ES2563439T5 (es) 2022-02-04
IL256110A (en) 2018-02-28
RS60094B1 (sr) 2020-05-29
CN105251003A (zh) 2016-01-20
CY1120227T1 (el) 2018-12-12
PL2632954T3 (pl) 2016-05-31
PT3018145T (pt) 2018-05-17
PL3412687T3 (pl) 2020-07-27
CL2013001138A1 (es) 2014-11-14
CA2815119A1 (en) 2012-05-03
ME02311B (me) 2016-06-20
KR101889995B1 (ko) 2018-08-20
JP2013540799A (ja) 2013-11-07
US10696744B2 (en) 2020-06-30
EP2632954B1 (en) 2015-11-25
MA34619B1 (fr) 2013-10-02
AU2011322581A1 (en) 2013-05-09
CY1123251T1 (el) 2021-10-29
DK2632954T3 (en) 2016-02-01
EP3412687A1 (en) 2018-12-12
ES2787044T3 (es) 2020-10-14
SI2632954T1 (sl) 2016-02-29
SMT202000232T1 (it) 2020-07-08
MY163057A (en) 2017-08-15
IL256110B (en) 2018-08-30
CA2815119C (en) 2023-01-10
PL2632954T5 (pl) 2021-11-02
IL260774B (en) 2019-02-28
HRP20151444T1 (hr) 2016-01-29
SI2632954T2 (sl) 2021-11-30
EP2632954B2 (en) 2021-07-07
DK3412687T3 (da) 2020-05-11
EP3018145B1 (en) 2018-04-04
RS54525B2 (sr) 2021-08-31
DK2632954T4 (da) 2021-08-09
JP2018039838A (ja) 2018-03-15
JP2016164192A (ja) 2016-09-08

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