PL2993186T3 - Przeciwciało monoklonalne i sposób jego otrzymywania - Google Patents
Przeciwciało monoklonalne i sposób jego otrzymywaniaInfo
- Publication number
- PL2993186T3 PL2993186T3 PL15171431T PL15171431T PL2993186T3 PL 2993186 T3 PL2993186 T3 PL 2993186T3 PL 15171431 T PL15171431 T PL 15171431T PL 15171431 T PL15171431 T PL 15171431T PL 2993186 T3 PL2993186 T3 PL 2993186T3
- Authority
- PL
- Poland
- Prior art keywords
- monoclonal antibody
- monoclonal
- antibody
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN650CH2008 | 2008-03-14 | ||
EP15171431.8A EP2993186B1 (en) | 2008-03-14 | 2008-09-04 | A monoclonal antibody and a method thereof |
EP08873217A EP2265644A4 (en) | 2008-03-14 | 2008-09-04 | MONOCLONAL ANTIBODY AND CORRESPONDING METHOD |
PCT/IN2008/000562 WO2009113083A1 (en) | 2008-03-14 | 2008-09-04 | A monoclonal antibody and a method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2993186T3 true PL2993186T3 (pl) | 2020-02-28 |
Family
ID=41064805
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL15171431T PL2993186T3 (pl) | 2008-03-14 | 2008-09-04 | Przeciwciało monoklonalne i sposób jego otrzymywania |
Country Status (26)
Country | Link |
---|---|
US (7) | US8524233B2 (pl) |
EP (2) | EP2993186B1 (pl) |
JP (3) | JP2011513479A (pl) |
KR (1) | KR20100126811A (pl) |
CN (1) | CN101970493A (pl) |
AR (1) | AR072247A1 (pl) |
AU (1) | AU2008352540B2 (pl) |
BR (1) | BRPI0822447A2 (pl) |
CA (1) | CA2716919C (pl) |
CL (1) | CL2009000618A1 (pl) |
CO (1) | CO6331445A2 (pl) |
DK (1) | DK2993186T3 (pl) |
EA (1) | EA201001467A1 (pl) |
ES (1) | ES2759075T3 (pl) |
HK (1) | HK1223941A1 (pl) |
IL (1) | IL207917A0 (pl) |
MX (1) | MX2010010085A (pl) |
MY (1) | MY159517A (pl) |
NZ (1) | NZ587632A (pl) |
PL (1) | PL2993186T3 (pl) |
PT (1) | PT2993186T (pl) |
TW (1) | TWI485160B (pl) |
UA (1) | UA104587C2 (pl) |
UY (1) | UY31710A (pl) |
WO (1) | WO2009113083A1 (pl) |
ZA (1) | ZA201005843B (pl) |
Families Citing this family (31)
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PT2119453E (pt) * | 2006-12-26 | 2015-09-01 | Ct De Inmunolgã A Molecular | Composições farmacêuticas capazes de induzir apoptose em células tumorais, úteis para o diagnóstico e o tratamento da leucemia linfocítica crónica de células |
EA201001467A1 (ru) | 2008-03-14 | 2011-06-30 | Биокон Лимитед | Моноклональное антитело и способ его использования |
US8822663B2 (en) | 2010-08-06 | 2014-09-02 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
CN104531812A (zh) | 2010-10-01 | 2015-04-22 | 现代治疗公司 | 设计核酸及其使用方法 |
US8710200B2 (en) | 2011-03-31 | 2014-04-29 | Moderna Therapeutics, Inc. | Engineered nucleic acids encoding a modified erythropoietin and their expression |
US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
HUE057725T2 (hu) | 2011-10-03 | 2022-06-28 | Modernatx Inc | Módosított nukleozidok, nukleotidok és nukleinsavak és ezek felhasználása |
LT2791160T (lt) | 2011-12-16 | 2022-06-10 | Modernatx, Inc. | Modifikuotos mrnr sudėtys |
US9254311B2 (en) | 2012-04-02 | 2016-02-09 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins |
AU2013243954A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
PT2922554T (pt) | 2012-11-26 | 2022-06-28 | Modernatx Inc | Arn modificado nas porções terminais |
US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
WO2015011660A1 (en) * | 2013-07-23 | 2015-01-29 | Biocon Limited | Methods for controlling fucosylation levels in proteins |
DK3024485T3 (da) | 2013-07-23 | 2020-12-07 | Biocon Ltd | Anvendelse af en CD6-bindingspartner og fremgangsmåde baseret derpå |
EP3052106A4 (en) | 2013-09-30 | 2017-07-19 | ModernaTX, Inc. | Polynucleotides encoding immune modulating polypeptides |
AU2014329452B2 (en) | 2013-10-03 | 2019-06-20 | Moderna Therapeutics, Inc. | Polynucleotides encoding low density lipoprotein receptor |
CN104497141B (zh) * | 2014-12-31 | 2017-10-10 | 百泰生物药业有限公司 | 抗人cd6分子的治疗性抗体 |
JP6930916B2 (ja) * | 2015-02-12 | 2021-09-01 | ユニヴァーシティ オブ サザン カリフォルニアUniversity of Southern California | 疾患予防および治療における成長ホルモン受容体の遮断剤 |
US10562975B2 (en) | 2016-06-15 | 2020-02-18 | The Regents Of The University Of Michigan | CD6 antibody for treatment of T-cell mediated diseases or disorders |
EP3528846A4 (en) * | 2016-10-18 | 2020-06-03 | Biocon Limited | USE OF ITOLIZUMAB TO REDUCE PHOSPHORYLATION OF CD6 |
PL3529274T3 (pl) * | 2016-10-21 | 2024-09-09 | Biocon Limited | Przeciwciało monoklonalne i sposób jego stosowania w leczeniu tocznia |
CN108178797B (zh) * | 2017-12-29 | 2020-12-01 | 西南大学 | 一种抗家蚕BmSRC多克隆抗血清、制备方法及应用 |
EP3759140A1 (en) | 2018-02-27 | 2021-01-06 | Equillium, Inc. | Anti cd6 antibodies for treating severe asthma |
JP7376564B2 (ja) * | 2018-06-29 | 2023-11-08 | シティ・オブ・ホープ | 特定の自己免疫疾患を治療するためのcd6標的キメラ抗原受容体 |
CN113490511B (zh) * | 2019-02-26 | 2024-07-09 | 伊奎利厄姆股份有限公司 | 用于治疗狼疮的抗cd6抗体组合物和方法 |
WO2020232247A1 (en) | 2019-05-14 | 2020-11-19 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
US20230151107A1 (en) * | 2020-04-04 | 2023-05-18 | Biocon Limited | Anti-cd6 antibody compositions and methods for treating and reducing negative effects of a coronavirus including covid-19 |
US12006366B2 (en) | 2020-06-11 | 2024-06-11 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
AU2022344418A1 (en) | 2021-09-08 | 2024-04-04 | Centro De Inmunologia Molecular | Use of anti-cd6 monoclonal antibodies in the prevention of cellular and organ damage resulting from hyper- inflammatory response |
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JPH09508784A (ja) | 1993-11-02 | 1997-09-09 | デューク ユニヴァーシティー | Cd6リガンド |
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BR9708231A (pt) | 1996-03-20 | 1999-08-03 | Hoechst Marion Roussel Inc | Compostos tricíclicos que têm uma atividade face a integrinas principalmente face à integrina alfavbeta3 seu processo de preparação e os intermediários desse processo sua aplicação a título de medicamentos e composiçóes farmacêuticas que os contêm |
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DK1176981T3 (da) | 1999-05-07 | 2006-04-10 | Genentech Inc | Behandling af autoimmune sygdomme med antagonister som binder til B celleoverflademarkörer |
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ES2192128B1 (es) | 2001-04-27 | 2005-01-01 | Universidad De Vigo | Anticuerpo monoclonal humano que reconoce especificamente la molecula humana cd69, y su uso en terapia. |
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EP2119452B1 (en) | 2006-12-26 | 2020-03-04 | Centro de Inmunologia Molecular | Pharmaceutical composition, comprising an anti-cd6 monoclonal antibody used in the diagnosis and treatment of rheumatoid arthritis |
PT2119453E (pt) | 2006-12-26 | 2015-09-01 | Ct De Inmunolgã A Molecular | Composições farmacêuticas capazes de induzir apoptose em células tumorais, úteis para o diagnóstico e o tratamento da leucemia linfocítica crónica de células |
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MX2012005863A (es) | 2009-11-20 | 2013-01-18 | Centro Inmunologia Molecular | Formulaciones de anticuerpos. |
CN102559636B (zh) | 2011-12-30 | 2014-03-12 | 百泰生物药业有限公司 | 用于白血病和自身免疫疾病的抗体融合蛋白及其制备方法 |
DK3024485T3 (da) | 2013-07-23 | 2020-12-07 | Biocon Ltd | Anvendelse af en CD6-bindingspartner og fremgangsmåde baseret derpå |
WO2015011660A1 (en) | 2013-07-23 | 2015-01-29 | Biocon Limited | Methods for controlling fucosylation levels in proteins |
US10562975B2 (en) | 2016-06-15 | 2020-02-18 | The Regents Of The University Of Michigan | CD6 antibody for treatment of T-cell mediated diseases or disorders |
WO2018024896A1 (en) | 2016-08-05 | 2018-02-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | EX VIVO GENERATION OF γδ FOXP3+ REGULATORY T CELLS AND THERAPEUTIC USES THEREOF |
EP3528846A4 (en) | 2016-10-18 | 2020-06-03 | Biocon Limited | USE OF ITOLIZUMAB TO REDUCE PHOSPHORYLATION OF CD6 |
PL3529274T3 (pl) | 2016-10-21 | 2024-09-09 | Biocon Limited | Przeciwciało monoklonalne i sposób jego stosowania w leczeniu tocznia |
EP3759140A1 (en) | 2018-02-27 | 2021-01-06 | Equillium, Inc. | Anti cd6 antibodies for treating severe asthma |
CN113490511B (zh) | 2019-02-26 | 2024-07-09 | 伊奎利厄姆股份有限公司 | 用于治疗狼疮的抗cd6抗体组合物和方法 |
US20230151107A1 (en) | 2020-04-04 | 2023-05-18 | Biocon Limited | Anti-cd6 antibody compositions and methods for treating and reducing negative effects of a coronavirus including covid-19 |
MX2023006595A (es) | 2020-12-04 | 2023-08-11 | Equillium Inc | Metodos para dirigir selectivamente celulas con cd6alto y para disminuir la actividad de linfocitos tef. |
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