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PL2696848T3 - Freeze dried drug nanosuspensions - Google Patents

Freeze dried drug nanosuspensions

Info

Publication number
PL2696848T3
PL2696848T3 PL12713187T PL12713187T PL2696848T3 PL 2696848 T3 PL2696848 T3 PL 2696848T3 PL 12713187 T PL12713187 T PL 12713187T PL 12713187 T PL12713187 T PL 12713187T PL 2696848 T3 PL2696848 T3 PL 2696848T3
Authority
PL
Poland
Prior art keywords
freeze dried
dried drug
drug nanosuspensions
nanosuspensions
freeze
Prior art date
Application number
PL12713187T
Other languages
Polish (pl)
Inventor
Sabine Karine Katrien Inghelbrecht
Henning GIESELER
Jakob Andreas BEIROWSKI
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of PL2696848T3 publication Critical patent/PL2696848T3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL12713187T 2011-04-15 2012-04-13 Freeze dried drug nanosuspensions PL2696848T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161475811P 2011-04-15 2011-04-15
EP12713187.8A EP2696848B1 (en) 2011-04-15 2012-04-13 Freeze dried drug nanosuspensions
PCT/EP2012/056818 WO2012140220A1 (en) 2011-04-15 2012-04-13 Freeze dried drug nanosuspensions

Publications (1)

Publication Number Publication Date
PL2696848T3 true PL2696848T3 (en) 2020-12-28

Family

ID=45937395

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12713187T PL2696848T3 (en) 2011-04-15 2012-04-13 Freeze dried drug nanosuspensions

Country Status (22)

Country Link
US (5) US20140038996A1 (en)
EP (2) EP3799860B1 (en)
JP (1) JP6161593B2 (en)
CN (2) CN103764117A (en)
AU (1) AU2012241726C1 (en)
BR (1) BR112013026363B1 (en)
CA (1) CA2832410C (en)
CY (1) CY1123434T1 (en)
DK (1) DK2696848T3 (en)
ES (2) ES3037398T3 (en)
HK (1) HK1257447A1 (en)
HR (1) HRP20201241T1 (en)
HU (1) HUE050970T2 (en)
LT (1) LT2696848T (en)
MX (1) MX362344B (en)
PL (1) PL2696848T3 (en)
PT (1) PT2696848T (en)
RS (1) RS60651B1 (en)
RU (1) RU2643062C2 (en)
SI (1) SI2696848T1 (en)
SM (1) SMT202000504T1 (en)
WO (1) WO2012140220A1 (en)

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SMT202000447T1 (en) 2011-04-28 2020-09-10 Oncopeptides Ab Lyophilized preparation of cytotoxic dipeptides
US10285946B2 (en) 2012-10-26 2019-05-14 Oncopeptides Ab Lyophilized preparations of melphalan flufenamide
US20150246060A1 (en) 2013-03-15 2015-09-03 Iceutica Inc. Abiraterone Acetate Formulation and Methods of Use
SG11201507681PA (en) * 2013-03-15 2015-10-29 Iceutica Inc Abiraterone acetate formulation
US20150157646A1 (en) 2013-09-27 2015-06-11 Iceutica Inc. Abiraterone Steroid Formulation
HUP1500055A1 (en) * 2015-02-09 2016-08-29 Druggability Technologies Ip Holdco Ltd Complexes of abiraterone acetate, process for the preparation thereof and pharmaceutical compositions containing them
CN105902496B (en) * 2016-04-18 2019-10-25 沈阳药科大学 A treatment method for the solidification process of nano-suspension
US10507165B2 (en) * 2017-05-31 2019-12-17 Adienne Pharma & Biotech Sa Multi chamber flexible bag and methods of using same
RU2665383C9 (en) * 2017-06-22 2019-07-23 Общество с ограниченной ответственностью "Вириом" Pharmaceutical nanosuspension for treatment of hiv infection
CA3069069A1 (en) 2017-07-14 2019-01-17 Janssen Pharmaceutica Nv Long-acting formulations
RU2721562C1 (en) * 2019-06-04 2020-05-20 Автономная некоммерческая образовательная организация высшего образования "Сколковский институт науки и технологий" Method of loading inorganic nanoparticles or organic molecules into porous particles of micron or submicron size
CN111149795A (en) * 2020-01-14 2020-05-15 成都艾伟孚生物科技有限公司 Cryoprotectant and application thereof, sperm freezing liquid and preparation method thereof
CN113440529B (en) * 2020-03-25 2023-11-14 江苏恒瑞医药股份有限公司 Injectable pharmaceutical composition and preparation method thereof
WO2021222545A1 (en) * 2020-04-29 2021-11-04 The Texas A&M University System Naloxone nanoparticle compositions and methods thereof
JP2023533014A (en) 2020-07-09 2023-08-01 ヤンセン ファーマシューティカ エヌ.ベー. long-acting formulation
JP2023532982A (en) 2020-07-09 2023-08-01 ヤンセン ファーマシューティカ エヌ.ベー. long-acting formulation
WO2022008644A1 (en) 2020-07-09 2022-01-13 Janssen Pharmaceutica Nv Long-acting formulations
WO2022079739A1 (en) 2020-10-14 2022-04-21 Cipla Limited Fixed dose compositions of cabotegravir and rilpivirine
JP6886551B1 (en) * 2020-11-06 2021-06-16 医療法人祥和会 Local anesthetic for dentistry
CN112641950B (en) * 2021-01-12 2022-12-16 北京德立福瑞医药科技有限公司 Pharmaceutical composition containing insoluble antitumor active agent and preparation method thereof
WO2023108156A1 (en) * 2021-12-11 2023-06-15 Beloteca, Inc. Ziprasidone formulations
US20250127761A1 (en) * 2022-02-10 2025-04-24 Soligenix, Inc. Telmisartan Nanosuspension for Therapy of Respiratory Infections and Methods of Making and Using Same
TW202406551A (en) * 2022-04-22 2024-02-16 愛爾蘭商健生科學愛爾蘭無限公司 Freeze dried compositions
EP4593834A1 (en) 2022-09-28 2025-08-06 JANSSEN Pharmaceutica NV Long-acting formulations
WO2024068693A1 (en) 2022-09-28 2024-04-04 Janssen Pharmaceutica Nv Long-acting formulations
CN116115621A (en) * 2022-10-31 2023-05-16 广州鹏兴医药科技有限公司 Hydrochlorothiazide composition, preparation method thereof and hydrochlorothiazide microneedle transdermal patch
CN116421564B (en) * 2023-03-09 2024-11-12 云南中医药大学 Breviscapine nanoparticles and preparation method thereof
WO2025056094A1 (en) * 2023-09-15 2025-03-20 广州帝奇医药技术有限公司 Freeze-dried preparation, injection, and preparation method therefor
CN116919898B (en) * 2023-09-15 2023-12-19 北京星辉再生科技有限责任公司 Minoxidil nanocrystalline suspension composition, minoxidil nanocrystalline suspension, preparation method and application thereof

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US20050004049A1 (en) 1997-03-11 2005-01-06 Elan Pharma International Limited Novel griseofulvin compositions
WO2004050068A1 (en) * 2002-11-29 2004-06-17 Janssen Pharmaceutica N.V. Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base
CA2509101A1 (en) 2002-12-13 2004-07-01 Jagotec Ag A topical nanoparticulate spironolactone formulation
RU2331424C2 (en) * 2002-12-13 2008-08-20 Джеготек Аг Topical formulation, containing spironolactone nanoparticles
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Also Published As

Publication number Publication date
SMT202000504T1 (en) 2020-11-10
EP3799860A1 (en) 2021-04-07
US20220409616A1 (en) 2022-12-29
HRP20201241T1 (en) 2020-11-27
CA2832410C (en) 2019-07-23
EP3799860C0 (en) 2025-06-25
BR112013026363A2 (en) 2016-12-27
US10166231B2 (en) 2019-01-01
EP3799860B1 (en) 2025-06-25
HK1257447A1 (en) 2019-10-18
EP2696848B1 (en) 2020-07-22
AU2012241726C1 (en) 2017-09-14
CN103764117A (en) 2014-04-30
EP2696848A1 (en) 2014-02-19
WO2012140220A1 (en) 2012-10-18
US20160317534A1 (en) 2016-11-03
CA2832410A1 (en) 2012-10-18
RU2013150803A (en) 2015-05-20
CY1123434T1 (en) 2021-12-31
LT2696848T (en) 2020-09-10
PT2696848T (en) 2020-09-03
MX362344B (en) 2019-01-11
RU2643062C2 (en) 2018-01-30
BR112013026363B1 (en) 2021-10-13
US20190076428A1 (en) 2019-03-14
AU2012241726A1 (en) 2013-10-24
US20240148726A1 (en) 2024-05-09
DK2696848T3 (en) 2020-10-12
RS60651B1 (en) 2020-09-30
JP6161593B2 (en) 2017-07-12
AU2012241726B2 (en) 2017-04-27
US11389448B2 (en) 2022-07-19
JP2014515021A (en) 2014-06-26
HUE050970T2 (en) 2021-01-28
ES3037398T3 (en) 2025-10-01
MX2013011985A (en) 2013-11-04
CN108210469A (en) 2018-06-29
ES2823805T3 (en) 2021-05-10
US20140038996A1 (en) 2014-02-06
SI2696848T1 (en) 2020-10-30
US11819502B2 (en) 2023-11-21

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