PL2366703T3 - Postać polimorficzna pochodnej 2-amino-(nitroarylo)-tiazolu - Google Patents

Postać polimorficzna pochodnej 2-amino-(nitroarylo)-tiazolu

Info

Publication number: PL2366703T3
Authority: PL; Poland
Prior art keywords: nitroaryl; amino; polymorph form; thiazole derivative; thiazole
Prior art date: 2007-02-13

Application number

PL11170200T

Other languages

English (en)

Inventor

Alain Moussy

Philippe Reginault

François Bellamy

Anne Lermet

Original Assignee

Ab Science

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-02-13

Filing date

2008-02-13

Publication date

2015-02-27

2008-02-13 Application filed by Ab Science filed Critical Ab Science

2015-02-27 Publication of PL2366703T3 publication Critical patent/PL2366703T3/pl

Links

GOJUJUVQIVIZAV-UHFFFAOYSA-N 2-amino-4,6-dichloropyrimidine-5-carbaldehyde Chemical group NC1=NC(Cl)=C(C=O)C(Cl)=N1 GOJUJUVQIVIZAV-UHFFFAOYSA-N 0.000 title 1
125000004999 nitroaryl group Chemical group 0.000 title 1
150000007979 thiazole derivatives Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Physical Education & Sports Medicine (AREA)
Oncology (AREA)
Hematology (AREA)
Orthopedic Medicine & Surgery (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Communicable Diseases (AREA)
Neurosurgery (AREA)
Transplantation (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Neurology (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Catalysts (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PL11170200T 2007-02-13 2008-02-13 Postać polimorficzna pochodnej 2-amino-(nitroarylo)-tiazolu PL2366703T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US88958707P	2007-02-13	2007-02-13
EP11170200.7A EP2366703B1 (en)	2007-02-13	2008-02-13	Polymorph form of 2-amino (nitroaryl) thiazole derivative
EP08708929A EP2118099B1 (en)	2007-02-13	2008-02-13	Process for the synthesis of 2-aminothiazole compounds as kinase inhibitors

Publications (1)

Publication Number	Publication Date
PL2366703T3 true PL2366703T3 (pl)	2015-02-27

Family

ID=39332208

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL08708929T PL2118099T3 (pl)	2007-02-13	2008-02-13	Proces syntezy związków 2-aminotiazolu jako inhibitorów kinazy
PL11170200T PL2366703T3 (pl)	2007-02-13	2008-02-13	Postać polimorficzna pochodnej 2-amino-(nitroarylo)-tiazolu

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
PL08708929T PL2118099T3 (pl)	2007-02-13	2008-02-13	Proces syntezy związków 2-aminotiazolu jako inhibitorów kinazy

Country Status (23)

Country	Link
US (3)	US8153792B2 (pl)
EP (2)	EP2118099B1 (pl)
JP (2)	JP5568312B2 (pl)
KR (1)	KR20090110851A (pl)
CN (2)	CN101657446B (pl)
AR (1)	AR065337A1 (pl)
AT (1)	ATE515506T1 (pl)
AU (1)	AU2008214679A1 (pl)
BR (1)	BRPI0807626B1 (pl)
CA (2)	CA2970628C (pl)
ES (2)	ES2369617T3 (pl)
HR (2)	HRP20110709T1 (pl)
IL (1)	IL200320A0 (pl)
MA (1)	MA31180B1 (pl)
MX (1)	MX2009008665A (pl)
NZ (1)	NZ578944A (pl)
PL (2)	PL2118099T3 (pl)
RU (2)	RU2456285C2 (pl)
SI (2)	SI2366703T1 (pl)
TN (1)	TN2009000342A1 (pl)
TW (1)	TWI406862B (pl)
WO (1)	WO2008098949A2 (pl)
ZA (1)	ZA200905981B (pl)

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US8450302B2 (en)	2002-08-02	2013-05-28	Ab Science	2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors
AR080048A1 (es)	2010-01-28	2012-03-07	Ab Science	Tratamiento del tumor del estroma gastrointestinal (gist) con masitinib
WO2011092338A1 (en)	2010-02-01	2011-08-04	Ab Science	Combined treatment of pancreatic cancer with gemcitabine and masitinib
AR080380A1 (es)	2010-03-09	2012-04-04	Ab Science	Tratamiento de la demencia tipo alzheimer con masitinib
TW201204360A (en)	2010-04-20	2012-02-01	Ab Science	Treatment of multiple sclerosis with MASITINIB
US20130267484A1 (en)	2010-06-02	2013-10-10	Ab Science	Treatment of rheumatoid arthritis with masitinib
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HUE057398T2 (hu)	2016-03-25	2022-05-28	Ab Science	A masitinib alkalmazása egy amiotrófiás laterálszklerózisos beteg alpopuláció kezelésére
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US10696638B2 (en)	2017-12-26	2020-06-30	Industrial Technology Research Institute	Compounds for inhibiting AGC kinase and pharmaceutical compositions comprising the same
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EP4106759A1 (en)	2020-02-20	2022-12-28	AB Science	Masitinib for the treatment of a multiple sclerosis patient subpopulation
US20230226043A1 (en)	2020-04-10	2023-07-20	Ab Science	Use of masitinib for the treatment of coronavirus disease 2019 (covid-19)
CA3201259A1 (en)	2020-12-16	2022-06-23	Alain Moussy	Masitinib for the treatment of alzheimer's disease
EP4175639B1 (en)	2021-05-17	2023-10-25	AB Science	Masitinib for the treatment of castrate-resistant prostate cancer
CN115850258B (zh) *	2022-12-27	2024-09-24	东北林业大学	一种马赛替尼的合成方法

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2008
- 2008-02-13 SI SI200831294T patent/SI2366703T1/sl unknown
- 2008-02-13 MX MX2009008665A patent/MX2009008665A/es active IP Right Grant
- 2008-02-13 AR ARP080100620A patent/AR065337A1/es active IP Right Grant
- 2008-02-13 EP EP08708929A patent/EP2118099B1/en active Active
- 2008-02-13 ES ES08708929T patent/ES2369617T3/es active Active
- 2008-02-13 CA CA2970628A patent/CA2970628C/en active Active
- 2008-02-13 PL PL08708929T patent/PL2118099T3/pl unknown
- 2008-02-13 BR BRPI0807626-0A patent/BRPI0807626B1/pt active IP Right Grant
- 2008-02-13 CN CN2008800049044A patent/CN101657446B/zh active Active
- 2008-02-13 AU AU2008214679A patent/AU2008214679A1/en not_active Abandoned
- 2008-02-13 PL PL11170200T patent/PL2366703T3/pl unknown
- 2008-02-13 ES ES11170200.7T patent/ES2522169T3/es active Active
- 2008-02-13 CA CA2677586A patent/CA2677586C/en active Active
- 2008-02-13 RU RU2009132186/04A patent/RU2456285C2/ru active
- 2008-02-13 US US12/526,827 patent/US8153792B2/en active Active
- 2008-02-13 NZ NZ578944A patent/NZ578944A/en unknown
- 2008-02-13 JP JP2009549405A patent/JP5568312B2/ja active Active
- 2008-02-13 AT AT08708929T patent/ATE515506T1/de not_active IP Right Cessation
- 2008-02-13 WO PCT/EP2008/051704 patent/WO2008098949A2/en active Application Filing
- 2008-02-13 KR KR1020097016822A patent/KR20090110851A/ko not_active Withdrawn
- 2008-02-13 SI SI200830399T patent/SI2118099T1/sl unknown
- 2008-02-13 CN CN201310141370.2A patent/CN103342701B/zh active Active
- 2008-02-13 TW TW097105021A patent/TWI406862B/zh not_active IP Right Cessation
- 2008-02-13 EP EP11170200.7A patent/EP2366703B1/en active Active
2009
- 2009-08-10 IL IL200320A patent/IL200320A0/en unknown
- 2009-08-11 MA MA32161A patent/MA31180B1/fr unknown
- 2009-08-11 TN TNP2009000342A patent/TN2009000342A1/fr unknown
- 2009-08-28 ZA ZA2009/05981A patent/ZA200905981B/en unknown
2011
- 2011-10-05 HR HR20110709T patent/HRP20110709T1/hr unknown
2012
- 2012-03-08 US US13/415,249 patent/US8492545B2/en active Active
- 2012-04-12 RU RU2012114234/04A patent/RU2491286C1/ru active
2013
- 2013-05-10 US US13/891,639 patent/US8940894B2/en active Active
- 2013-05-30 JP JP2013113789A patent/JP5784073B2/ja active Active
2014
- 2014-10-15 HR HRP20140986AT patent/HRP20140986T1/hr unknown

Also Published As

Publication number	Publication date
CN101657446A (zh)	2010-02-24
TN2009000342A1 (en)	2010-12-31
HRP20140986T1 (hr)	2014-11-21
AR065337A1 (es)	2009-06-03
CN103342701A (zh)	2013-10-09
EP2366703B1 (en)	2014-07-30
TW200848419A (en)	2008-12-16
CA2970628A1 (en)	2008-08-21
JP5568312B2 (ja)	2014-08-06
RU2456285C2 (ru)	2012-07-20
US20120196871A1 (en)	2012-08-02
RU2491286C1 (ru)	2013-08-27
KR20090110851A (ko)	2009-10-22
CN103342701B (zh)	2016-09-21
PL2118099T3 (pl)	2011-12-30
US8492545B2 (en)	2013-07-23
CA2970628C (en)	2019-08-27
ES2369617T3 (es)	2011-12-02
WO2008098949A3 (en)	2008-10-02
CA2677586A1 (en)	2008-08-21
RU2009132186A (ru)	2011-03-20
BRPI0807626B1 (pt)	2022-03-03
MA31180B1 (fr)	2010-02-01
US20100121063A1 (en)	2010-05-13
JP5784073B2 (ja)	2015-09-24
US8153792B2 (en)	2012-04-10
CN101657446B (zh)	2013-05-15
AU2008214679A1 (en)	2008-08-21
MX2009008665A (es)	2009-08-21
EP2118099A2 (en)	2009-11-18
EP2118099B1 (en)	2011-07-06
JP2010518141A (ja)	2010-05-27
IL200320A0 (en)	2010-04-29
CA2677586C (en)	2017-07-25
JP2013177437A (ja)	2013-09-09
ZA200905981B (en)	2010-11-24
ATE515506T1 (de)	2011-07-15
EP2366703A1 (en)	2011-09-21
NZ578944A (en)	2011-03-31
BRPI0807626A2 (pt)	2014-11-25
US20130289045A1 (en)	2013-10-31
SI2366703T1 (sl)	2014-10-30
WO2008098949A2 (en)	2008-08-21
TWI406862B (zh)	2013-09-01
HRP20110709T1 (hr)	2011-11-30
SI2118099T1 (sl)	2011-11-30
US8940894B2 (en)	2015-01-27
ES2522169T3 (es)	2014-11-13

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